High-speed spectral nanocytology for early cancer screening

Journal of Biomedical Optics

Volumn 18, Issue 11, 2013, Pages

  Chandler, John E ^a   Subramanian, Hariharan ^a   Maneval, Charles D ^a   White, Craig A ^a   Levenson, Richard M ^b   Backman, Vadim ^a  

^a Northwestern University   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

cancer screening; cellular nanoarchitecture; light scattering spectroscopic microscopy

Indexed keywords

ACOUSTO-OPTIC TUNABLE FILTERS; CANCER SCREENING; CLINICAL DIAGNOSTICS; DIAGNOSTIC BIOMARKERS; EPIDERMAL GROWTH FACTOR RECEPTORS; HUMAN COLON CANCER CELLS; LUNG CANCER SCREENING; NANO-ARCHITECTURE;

CELL CULTURE; NANOSTRUCTURES; PIXELS;

DISEASES;

ALGORITHM; ARTICLE; CHEMISTRY; CYTOLOGY; EARLY DIAGNOSIS; EQUIPMENT; HT 29 CELL LINE; HUMAN; IMAGE QUALITY; LUNG TUMOR; METHODOLOGY; NANOMEDICINE; SENSITIVITY AND SPECIFICITY; SPECTROSCOPY; ULTRASTRUCTURE;

ALGORITHMS; CYTOLOGICAL TECHNIQUES; EARLY DETECTION OF CANCER; HT29 CELLS; HUMANS; LUNG NEOPLASMS; NANOMEDICINE; PHANTOMS, IMAGING; SENSITIVITY AND SPECIFICITY; SPECTRUM ANALYSIS;

EID: 84892588110     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.JBO.18.11.117002     Document Type: Article

References (31)

1. A. M. Minino et al., "Deaths: final data for 2008," Natl. Vital Stat. Rep. 59, 1-126 (2011).
2. J. Vansteenkiste et al., "Screening and early detection of lung cancer," Ann. Oncol. 23(Suppl 10), x320-x327 (2012).
3. F. S. Miller, L. E. Nagel, and M. B. Kenny-Moynihan, "Implementation of the ThinPrep imaging system in a high-volume metropolitan laboratory," Diagn. Cytopathol. 35(4), 213-217 (2007). (Pubitemid 46516675)
4. A. W. Levi et al., "Implementation of FocalPoint GS location-guided imaging system: experience in a clinical setting," Cancer Cytopathol. 120(2), 126-133 (2012).
5. T. M. Elsheikh et al., "Increasing cytotechnologist workload above 100 slides per day using the ThinPrep imaging system leads to significant reductions in screening accuracy," Cancer Cytopathol. 118(2), 75-82 (2010).
6. A. W. Levi et al., "Increasing cytotechnologist workload above 100 slides per day using the BD FocalPoint GS imaging system negatively affects screening performance," Am. J. Clin. Pathol. 138(6), 811-815 (2012).
7. T. M. Elsheikh et al., "American society of cytopathology workload recommendations for automated pap test screening: developed by the productivity and quality assurance in the era of automated screening task force," Diagn. Cytopathol. 41(2), 174-178 (2013).
8. S. S. Kecheril et al., "Automated lung cancer detection by the analysis of glandular cells in sputum cytology images using scale space features," Signal Image Video Process., 1-13 (2013).
9. S. Doyle et al., "A boosted Bayesian multiresolution classifier for prostate cancer detection from digitized needle biopsies," IEEE Trans. Biomed. Eng. 59(5), 1205-1218 (2012).
10. P. Filipczuk, M. Kowal, and A. Obuchowicz, "Automatic breast cancer diagnosis based on K-means clustering and adaptive thresholding hybrid segmentation," Image Process. Commun. Challenges 3. 102, 295-302 (2011).
11. N. Ikeda et al., "Malignancy associated changes in bronchial epithelial cells and clinical application as a biomarker," Lung Cancer 19(3), 161-166 (1998). (Pubitemid 28238466)
12. B. Susnik et al., "Malignancy-associated changes in the breast-changes in chromatin distribution in epithelial-cells in normal-appearing tissue adjacent to carcinoma," Anal. Quant. Cytol. Histol. 17(1), 62-68 (1995).
13. M. Us-Krasovec et al., "Malignancy associated changes in epithelial cells of buccal mucosa: a potential cancer detection test," Anal. Quant. Cytol. Histol. 27(5), 254-262 (2005). (Pubitemid 41504426)
14. R. A. Kemp et al., "Detection of malignancy associated changes in cervical cell nuclei using feed-forward neural networks," Anal. Cell. Pathol. 14(1), 31-40 (1997). (Pubitemid 27418105)
15. H. K. Roy et al., "Optical detection of buccal epithelial nanoarchitectural alterations in patients harboring lung cancer: implications for screening," Cancer Res. 70(20), 7748-7754 (2010).
16. H. Subramanian et al., "Optical methodology for detecting histologically unapparent nanoscale consequences of genetic alterations in biological cells," Proc. Natl. Acad. Sci. U. S. A. 105(51), 20118-20123 (2008).
17. H. Subramanian et al., "Nanoscale cellular changes in field carcinogenesis detected by partial wave spectroscopy," Cancer Res. 69(13), 5357-5363 (2009).
18. S. Chaitchik et al., "An evaluation of the SCM test for the diagnosis of cancer of the breast," Eur. J. Cancer Clin. Oncol. 24(5), 861-866 (1988).
19. M. Deutsch and A. Weinreb, "Validation of the SCM-test for the diagnosis of cancer," Eur. J. Cancer Clin. Oncol. 19(2), 187-193 (1983). (Pubitemid 13155856)
20. C. MacAulay et al., "Malignancy-associated changes in bronchial epithelial cells in biopsy specimens," Anal. Quant. Cytol. Histol. 17(1), 55-61 (1995).
21. Y. Liu et al., "Elastic backscattering spectroscopic microscopy," Opt. Lett. 30(18), 2445-2447 (2005). (Pubitemid 41463515)
22. J. S. Kim et al., "The influence of chromosome density variations on the increase in nuclear disorder strength in carcinogenesis," Phys. Biol. 8(1), 015004 (2011).
23. Y. Stypula et al., "Understanding biological mechanisms of nuclear disorder strength in early carcinogenesis," Gastroenterology 140, S765-S766 (2011).
24. L. Cherkezyan et al., "Targeted alteration of real and imaginary refractive index of biological cells by histological staining," Opt. Lett. 37(10), 1601-1603 (2012).
25. E. Hughlett and P. Kaiser, "An autofocus technique for imaging microscopy," in ICASSP-92-1992 Int. Conf. Acoustics, Speech, and Signal Processing, Vols. 3, pp. C93-C96 (1992).
26. D. Damania et al., "Insights into the field carcinogenesis of ovarian cancer based on the nanocytology of endocervical and endometrial epithelial cells," Int. J. Cancer 133(5), 1143-1152 (2013).
27. D. Damania et al., "Nanocytology of rectal colonocytes to assess risk of colon cancer based on field cancerization," Cancer Res. 72(11), 2720-2727 (2012).
28. H. Subramanian et al., "Nanoscale cellular changes in field carcinogenesis detected by partial wave spectroscopy," Cancer Res. 69(13), 5357-5363 (2009).
29. R. Siegel, D. Naishadham, and A. Jemal, "Cancer statistics, 2012," CA Cancer J. Clin. 62(1), 10-29 (2012).
30. D. R. Aberle et al., "Reduced lung-cancer mortality with low-dose computed tomographic screening," N. Engl. J. Med. 365, 395-409 (2011).
31. P. B. Bach et al., "Benefits and harms of CT screening for lung cancer: a systematic review," JAMA 307, 2418-2429 (2012).