Diabetes mellitus without metformin intake is associated with worse oncologic outcomes after radical nephroureterectomy for upper tract urothelial carcinoma

European Journal of Surgical Oncology

Volumn 40, Issue 1, 2014, Pages 113-120

  Rieken, M ^a,b   Xylinas, E ^a,c   Kluth, L ^a,d   Trinh, Q D ^m   Lee, R K ^a   Fajkovic, H ^l   Novara, G ^g   Margulis, V ^h   Lotan, Y ^h   Martinez Salamanca, J I ⁱ   Matsumoto, K ^j   Seitz, C ^l   Remzi, M ^k   Karakiewicz, P I ^f   Scherr, D S ^a   Briganti, A ^e   Kautzky Willer, A ^l   Bachmann, A ^b   Shariat, S F ^a,l  

^a NEW YORK PRESBYTERIAN HOSPITAL   (United States)

^b UNIVERSITY HOSPITAL BASEL   (Switzerland)

^c Institut Cochin   (France)

^d UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^e VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

^f UNIVERSITÉ DE MONTRÉAL   (Canada)

^g UNIVERSITY OF PADOVA   (Italy)

^h UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

ⁱ HOSPITAL UNIVERSITARIO PUERTA DE HIERRO   (Spain)

^j KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^k Landesklinikum Korneuburg ^*  (Austria)

^l MEDICAL UNIVERSITY OF VIENNA   (Austria)

^m BRIGHAM AND WOMEN S HOSPITAL   (United States)

more..

Author keywords

Diabetes mellitus; Metformin; Surgery; Upper tract urothelial carcinoma

Indexed keywords

METFORMIN;

ADULT; AGED; ARTICLE; CANCER ADJUVANT THERAPY; CANCER LOCALIZATION; CANCER MORTALITY; CANCER PATIENT; CANCER SURGERY; CANCER SURVIVAL; CONTROLLED STUDY; CORRELATIONAL STUDY; DIABETES MELLITUS; DIABETIC PATIENT; DISEASE SEVERITY; DRUG USE; FEMALE; FOLLOW UP; HUMAN; LYMPH NODE METASTASIS; LYMPH VESSEL METASTASIS; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; NEPHROURETERECTOMY; PRIORITY JOURNAL; RECURRENCE FREE SURVIVAL; RECURRENT DISEASE; RETROSPECTIVE STUDY; TRANSITIONAL CELL CARCINOMA; TUMOR INVASION;

DIABETES MELLITUS; METFORMIN; SURGERY; UPPER TRACT UROTHELIAL CARCINOMA;

AGED; CARCINOMA, TRANSITIONAL CELL; DIABETES MELLITUS; FEMALE; FOLLOW-UP STUDIES; HUMANS; HYPOGLYCEMIC AGENTS; KAPLAN-MEIER ESTIMATE; KIDNEY NEOPLASMS; LYMPHATIC METASTASIS; MALE; METFORMIN; MIDDLE AGED; NEOPLASM GRADING; NEOPLASM INVASIVENESS; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; NEPHRECTOMY; PROPORTIONAL HAZARDS MODELS; RETROSPECTIVE STUDIES; TREATMENT OUTCOME; URETERAL NEOPLASMS; URETEROSCOPY; UROLOGIC SURGICAL PROCEDURES;

EID: 84892526938     PISSN: 07487983     EISSN: 15322157     Source Type: Journal    
DOI: 10.1016/j.ejso.2013.09.016     Document Type: Article

References (30)

1. M. Rink, D. Sjoberg, and E. Comploj et al. Risk of cancer-specific mortality following recurrence after radical nephroureterectomy Ann Surg Oncol 19 13 2012 4337 4344
2. R. Siegel, D. Naishadham, and A. Jemal Cancer statistics, 2012 CA Cancer J Clin 62 1 2012 10 29
3. V. Margulis, S.F. Shariat, and S.F. Matin et al. Outcomes of radical nephroureterectomy: a series from the Upper Tract Urothelial Carcinoma Collaboration Cancer 115 6 2009 1224 1233
4. M. Roupret, R. Zigeuner, and J. Palou et al. European guidelines for the diagnosis and management of upper urinary tract urothelial cell carcinomas: 2011 update Eur Urol 59 4 2011 584 594
5. A.A. Onitilo, J.M. Engel, I. Glurich, R.V. Stankowski, G.M. Williams, and S.A. Doi Diabetes and cancer I: risk, survival, and implications for screening Cancer Causes Control 23 6 2012 967 981
6. E.C. Hwang, Y.J. Kim, and I.S. Hwang et al. Impact of diabetes mellitus on recurrence and progression in patients with non-muscle invasive bladder carcinoma: a retrospective cohort study Int J Urol Off - J Jpn Urol Assoc. 18 11 2011 769 776
7. J.M. Evans, L.A. Donnelly, A.M. Emslie-Smith, D.R. Alessi, and A.D. Morris Metformin and reduced risk of cancer in diabetic patients BMJ 330 7503 2005 1304 1305
8. G.W. Landman, N. Kleefstra, K.J. van Hateren, K.H. Groenier, R.O. Gans, and H.J. Bilo Metformin associated with lower cancer mortality in type 2 diabetes: ZODIAC-16 Diabetes Care 33 2 2010 322 326
9. A. Decensi, M. Puntoni, and P. Goodwin et al. Metformin and cancer risk in diabetic patients: a systematic review and meta-analysis Cancer Prev Res. 3 11 2010 1451 1461
10. E. Xylinas, M. Rink, and E.K. Cha et al. Impact of Distal Ureter Management on Oncologic Outcomes Following Radical Nephroureterectomy for Upper Tract Urothelial Carcinoma Eur Urol 2012 [in press] http://dx.doi.org/10.1016/j. eururo.2012.04.052
11. J.I. Epstein, M.B. Amin, V.R. Reuter, F.K. Mostofi, and B.C.C. Comm The World Health Organization International Society of Urological Pathology consensus classification of urothelial (transitional cell) neoplasms of the urinary bladder Am J Surg Pathol 22 12 1998 1435 1448
12. M. Rink, H. Fajkovic, and E.K. Cha et al. Death certificates are valid for the determination of cause of death in patients with upper and lower tract urothelial carcinoma Eur Urol 61 4 2012 854 855
13. D.E. Spratt, C. Zhang, Z.S. Zumsteg, X. Pei, Z. Zhang, and M.J. Zelefsky Metformin and prostate cancer: reduced development of castration-resistant disease and prostate cancer mortality Eur Urol 63 4 2013 709 716
14. J.Y. Jeon, D.H. Jeong, and M.G. Park et al. Impact of diabetes on oncologic outcome of colorectal cancer patients: colon vs. rectal cancer PloS one 8 2 2013 e55196
15. M.M. Zanders, D. Boll, L.N. van Steenbergen, L.V. van de Poll-Franse, and H.R. Haak Effect of diabetes on endometrial cancer recurrence and survival Maturitas 74 1 2013 37 43
16. J.J. Oh, S.K. Hong, S. Lee, S.J. Sohn, and S.E. Lee Diabetes mellitus is associated with short prostate-specific antigen doubling time after radical prostatectomy Int Urol Nephrol 45 1 2013 121 127
17. C.F. Snyder, K.B. Stein, and B.B. Barone et al. Does pre-existing diabetes affect prostate cancer prognosis? A systematic review Prostate Cancer Prostatic Dis 13 1 2010 58 64
18. C.T. Ting, R.C. Chen, C.C. Chen, M.H. Liu, D. Chu, and N.W. Kuo Diabetes worsens the surgical outcomes in cirrhotic patients with hepatocellular carcinoma Tohoku J Exp Med 227 1 2012 73 81
19. J. Varlotto, L.N. Medford-Davis, and A. Recht et al. Confirmation of the role of diabetes in the local recurrence of surgically resected non-small cell lung cancer Lung cancer 75 3 2012 381 390
20. S. Liu, Y. Li, T. Lin, X. Fan, Y. Liang, and U. Heemann High dose human insulin and insulin glargine promote T24 bladder cancer cell proliferation via PI3K-independent activation of Akt Diabetes Res Clin Pract 91 2 2011 177 182
21. D. Metalli, F. Lovat, and F. Tripodi et al. The insulin-like growth factor receptor I promotes motility and invasion of bladder cancer cells through Akt- and mitogen-activated protein kinase-dependent activation of paxillin Am J Pathol 176 6 2010 2997 3006
22. M. Jalving, J.A. Gietema, and J.D. Lefrandt et al. Metformin: taking away the candy for cancer? Eur J Cancer 46 13 2010 2369 2380
23. Z. Zhu, X. Zhang, and Z. Shen et al. Diabetes mellitus and risk of bladder cancer: a meta-analysis of cohort studies PloS one 8 2 2013 e56662
24. W.Y. Shau, Y.Y. Shao, and Y.C. Yeh et al. Diabetes mellitus is associated with increased mortality in patients receiving curative therapy for hepatocellular carcinoma Oncologist 17 6 2012 856 862
25. L.V. van de Poll-Franse, H.R. Haak, J.W. Coebergh, M.L. Janssen-Heijnen, and V.E. Lemmens Disease-specific mortality among stage I-III colorectal cancer patients with diabetes: a large population-based analysis Diabetologia 55 8 2012 2163 2172
26. W.W. Chen, Y.Y. Shao, and W.Y. Shau et al. The impact of diabetes mellitus on prognosis of early breast cancer in Asia Oncologist 17 4 2012 485 491
27. C.C. Newton, S.M. Gapstur, P.T. Campbell, and E.J. Jacobs Type 2 diabetes mellitus, insulin-use and risk of bladder cancer in a large cohort study Int J Cancer 132 9 2013 May 1 2186 2191
28. I.N. Colmers, S.L. Bowker, S.R. Majumdar, and J.A. Johnson Use of thiazolidinediones and the risk of bladder cancer among people with type 2 diabetes: a meta-analysis CMAJ: Can Med Assoc J - J de l'Association medicale canadienne 184 12 2012 E675 E683
29. R. Mamtani, K. Haynes, and W.B. Bilker et al. Association between longer therapy with thiazolidinediones and risk of bladder cancer: a cohort study J Natl Cancer Inst 104 18 2012 1411 1421
30. D. Hillaire-Buys, J.L. Faillie, and J.L. Montastruc Pioglitazone and bladder cancer Lancet 378 9802 2011 1543 1544 author reply 4-5