Exploring the minimally frustrated energy landscape of unfolded ACBP

Journal of Molecular Biology

Volumn 426, Issue 3, 2014, Pages 722-734

  Ozenne, Valéry ^a   Noel, Jeffrey K ^b   Heidarsson, Pétur O ^c   Brander, Søren ^c   Poulsen, Flemming M ^c   Jensen, Malene Ringkjøbing ^a   Kragelund, Birthe B ^c   Blackledge, Martin ^a   Danielsson, Jens ^c,d  

^a INSTITUT DE BIOLOGIE STRUCTURALE   (France)

^b RICE UNIVERSITY   (United States)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

ensemble selection; protein folding; residual structure; transient contacts; unfolded free energy landscape

Indexed keywords

ACYL COENZYME BINDING PROTEIN; BINDING PROTEIN; GLOBULAR PROTEIN; INTRINSICALLY DISORDERED PROTEIN; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; COMPUTER MODEL; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; ENZYME BINDING; ESCHERICHIA COLI; HYDROPHOBICITY; MOLECULAR DYNAMICS; NONHUMAN; POINT MUTATION; PREDICTIVE VALUE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; PROTEIN UNFOLDING; PROTON NUCLEAR MAGNETIC RESONANCE; SIGNAL TRANSDUCTION; STATIC ELECTRICITY; WILD TYPE; ENERGY; PROTEIN STABILITY; PROTEIN STRUCTURE;

ACBP; ACYL CO-ENZYME BINDING PROTEIN; ENSEMBLE SELECTION; FLUORESCENCE RESONANCE ENERGY TRANSFER; FRET; PARAMAGNETIC RELAXATION ENHANCEMENT; PRE; PROTEIN FOLDING; RESIDUAL STRUCTURE; SECONDARY STRUCTURE PROPENSITY; SSP; TRANSIENT CONTACTS; TRANSITION-STATE ENSEMBLE; TSE; UNFOLDED FREE-ENERGY LANDSCAPE;

ANIMALS; CATTLE; DIAZEPAM BINDING INHIBITOR; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; POINT MUTATION; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN FOLDING;

EID: 84892500140     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2013.10.031     Document Type: Article

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