-
1
-
-
42949171158
-
-
American Cancer Society, Atlanta, GA American Cancer Society
-
American Cancer Society Global cancer facts and figures 2008, American Cancer Society, Atlanta, GA. 2nd ed.
-
(2008)
Global cancer facts and figures
-
-
-
2
-
-
0024337144
-
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
-
Slamon D.J., Godolphin W., Jones L.A., et al. Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 1989, 244:707-712.
-
(1989)
Science
, vol.244
, pp. 707-712
-
-
Slamon, D.J.1
Godolphin, W.2
Jones, L.A.3
-
3
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
Slamon D.J., Leyland-Jones B., Shak S., et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. NEngl J Med 2001, 344:783-792.
-
(2001)
NEngl J Med
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
-
4
-
-
80053539103
-
Adjuvant trastuzumab in HER2-positive breast cancer
-
Slamon D., Eiermann W., Robert N., et al. Adjuvant trastuzumab in HER2-positive breast cancer. NEngl J Med 2011, 365:1273-1283.
-
(2011)
NEngl J Med
, vol.365
, pp. 1273-1283
-
-
Slamon, D.1
Eiermann, W.2
Robert, N.3
-
5
-
-
22344446208
-
Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: the M77001 study group
-
Marty M., Cognetti F., Maraninchi D., et al. Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: the M77001 study group. JClin Oncol 2005, 23:4265-4274.
-
(2005)
JClin Oncol
, vol.23
, pp. 4265-4274
-
-
Marty, M.1
Cognetti, F.2
Maraninchi, D.3
-
6
-
-
79952041937
-
Treatment with trastuzumab for 1 year after adjuvant chemotherapy in patients with HER2-positive early breast cancer: a 4-year follow-up of a randomised controlled trial
-
Gianni L., Dafni U., Gelber R.D., et al. Treatment with trastuzumab for 1 year after adjuvant chemotherapy in patients with HER2-positive early breast cancer: a 4-year follow-up of a randomised controlled trial. Lancet Oncol 2011, 12:236-244.
-
(2011)
Lancet Oncol
, vol.12
, pp. 236-244
-
-
Gianni, L.1
Dafni, U.2
Gelber, R.D.3
-
7
-
-
65549170412
-
Mechanisms of trastuzumab resistance in breast cancer
-
Tolaney S.M., Krop I.E. Mechanisms of trastuzumab resistance in breast cancer. Anticancer Agents Med Chem 2009, 9:348-355.
-
(2009)
Anticancer Agents Med Chem
, vol.9
, pp. 348-355
-
-
Tolaney, S.M.1
Krop, I.E.2
-
8
-
-
0029813044
-
Treatment of advanced breast cancer: current status
-
Piccart M. Treatment of advanced breast cancer: current status. Anticancer Drugs 1996, 7(Suppl. 2):5-7.
-
(1996)
Anticancer Drugs
, vol.7
, Issue.SUPPL. 2
, pp. 5-7
-
-
Piccart, M.1
-
9
-
-
33645538673
-
Analysis of trastuzumab and chemotherapy in advanced breast cancer after the failure of at least one earlier combination: an observational study
-
Bartsch R., Wenzel C., Hussian D., et al. Analysis of trastuzumab and chemotherapy in advanced breast cancer after the failure of at least one earlier combination: an observational study. BMC Cancer 2006, 6:63.
-
(2006)
BMC Cancer
, vol.6
, pp. 63
-
-
Bartsch, R.1
Wenzel, C.2
Hussian, D.3
-
10
-
-
84892483559
-
®) retreatment in patients who relapse following adjuvant trastuzumab therapy: preliminary efficacy data from the RHEA trial
-
Abstract 245
-
®) retreatment in patients who relapse following adjuvant trastuzumab therapy: preliminary efficacy data from the RHEA trial. ASCO Breast 2007, Abstract 245.
-
(2007)
ASCO Breast
-
-
Bell, R.1
Feng-Yi, F.2
Barrios, C.H.3
-
11
-
-
57849117384
-
New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1)
-
Eisenhauer E.A., Therasse P., Bogarts J., et al. New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur J Cancer 2009, 45:228-247.
-
(2009)
Eur J Cancer
, vol.45
, pp. 228-247
-
-
Eisenhauer, E.A.1
Therasse, P.2
Bogarts, J.3
-
12
-
-
0003809049
-
-
American Joint Committee on Cancer, Chicago, IL, American Joint Committee on Cancer (AJCC)
-
American Joint Committee on Cancer (AJCC) Cancer staging manual 1997, American Joint Committee on Cancer, Chicago, IL. 5th ed.
-
(1997)
Cancer staging manual
-
-
-
13
-
-
0001072895
-
The use of confidence or fiducial limits illustrated in the case of the binomial
-
Clopper C.J., Pearson E.S. The use of confidence or fiducial limits illustrated in the case of the binomial. Biometrika 1934, 26:404-413.
-
(1934)
Biometrika
, vol.26
, pp. 404-413
-
-
Clopper, C.J.1
Pearson, E.S.2
-
15
-
-
34249672864
-
Trastuzumab: triumphs and tribulations
-
Nahta R., Esteva F.J. Trastuzumab: triumphs and tribulations. Oncogene 2007, 26:3637-3643.
-
(2007)
Oncogene
, vol.26
, pp. 3637-3643
-
-
Nahta, R.1
Esteva, F.J.2
-
16
-
-
72449139053
-
Randomized phase III trial of trastuzumab monotherapy followed by trastuzumab plus docetaxel versus trastuzumab plus docetaxel as first-line therapy in patients with HER2-positive metastatic breast cancer: the JO17360 Trial Group
-
Inoue K., Nakagami K., Mizutani M., et al. Randomized phase III trial of trastuzumab monotherapy followed by trastuzumab plus docetaxel versus trastuzumab plus docetaxel as first-line therapy in patients with HER2-positive metastatic breast cancer: the JO17360 Trial Group. Breast Cancer Res Treat 2010, 119:127-136.
-
(2010)
Breast Cancer Res Treat
, vol.119
, pp. 127-136
-
-
Inoue, K.1
Nakagami, K.2
Mizutani, M.3
-
17
-
-
84892483799
-
-
Trastuzumab, summary of product characteristics [cited March 2012]. Available at:
-
Trastuzumab, summary of product characteristics [cited March 2012]. Available at: http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/000278/WC500074922.pdf.
-
-
-
-
18
-
-
77949893849
-
Randomized phase II trial of first-line trastuzumab plus docetaxel and capecitabine compared with trastuzumab plus docetaxel in HER2-positive metastatic breast cancer
-
Wardley A.M., Pivot X., Morales-Vasquez F., et al. Randomized phase II trial of first-line trastuzumab plus docetaxel and capecitabine compared with trastuzumab plus docetaxel in HER2-positive metastatic breast cancer. JClin Oncol 2010, 28:976-983.
-
(2010)
JClin Oncol
, vol.28
, pp. 976-983
-
-
Wardley, A.M.1
Pivot, X.2
Morales-Vasquez, F.3
-
19
-
-
0032850677
-
Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
-
Cobleigh M.A., Vogel C.L., Tripathy D., et al. Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. JClin Oncol 1999, 17:2639-2648.
-
(1999)
JClin Oncol
, vol.17
, pp. 2639-2648
-
-
Cobleigh, M.A.1
Vogel, C.L.2
Tripathy, D.3
-
20
-
-
84892483262
-
-
Original efficacy data [cited March 2012]. Available at:
-
Original efficacy data [cited March 2012]. Available at: http://www.rochetrials.com/studyResultGet.action?studyResultNumber=WO16229.
-
-
-
-
21
-
-
84892476224
-
-
Original efficacy data [cited March 2012]. Available at:
-
Original efficacy data [cited March 2012]. Available at: http://www.rochetrials.com/studyResultGet.action?studyResultNumber=MO16982.
-
-
-
-
22
-
-
84862914692
-
Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer
-
Baselga J., Cortés J., Kim S.B., et al. Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer. NEngl J Med 2012, 366:109-119.
-
(2012)
NEngl J Med
, vol.366
, pp. 109-119
-
-
Baselga, J.1
Cortés, J.2
Kim, S.B.3
-
23
-
-
52049088286
-
Cardiac toxicity and efficacy of trastuzumab combined with pertuzumab in patients with trastuzumab-insensitive human epidermal growth factor receptor 2-positive metastatic breast cancer
-
Portera C.C., Walshe J.M., Rosing D.R., et al. Cardiac toxicity and efficacy of trastuzumab combined with pertuzumab in patients with trastuzumab-insensitive human epidermal growth factor receptor 2-positive metastatic breast cancer. Clin Cancer Res 2008, 14:2710-2716.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 2710-2716
-
-
Portera, C.C.1
Walshe, J.M.2
Rosing, D.R.3
-
24
-
-
77949884661
-
Randomized study of lapatinib alone or in combination with trastuzumab in women with ErbB2-positive, trastuzumab-refractory metastatic breast cancer
-
Blackwell K.L., Burstein H.J., Storniolo A.M., et al. Randomized study of lapatinib alone or in combination with trastuzumab in women with ErbB2-positive, trastuzumab-refractory metastatic breast cancer. JClin Oncol 2010, 28:1124-1130.
-
(2010)
JClin Oncol
, vol.28
, pp. 1124-1130
-
-
Blackwell, K.L.1
Burstein, H.J.2
Storniolo, A.M.3
-
25
-
-
77949903478
-
Phase II trial of pertuzumab and trastuzumab in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer that progressed during prior trastuzumab therapy
-
Baselga J., Gelmon K.A., Verma S., et al. Phase II trial of pertuzumab and trastuzumab in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer that progressed during prior trastuzumab therapy. JClin Oncol 2010, 28:1138-1144.
-
(2010)
JClin Oncol
, vol.28
, pp. 1138-1144
-
-
Baselga, J.1
Gelmon, K.A.2
Verma, S.3
-
26
-
-
84868520609
-
Trastuzumab emtansine for HER2-positive advanced breast cancer
-
Verma S., Miles D., Gianni L., et al. Trastuzumab emtansine for HER2-positive advanced breast cancer. NEngl J Med 2012, 367:1783-1791.
-
(2012)
NEngl J Med
, vol.367
, pp. 1783-1791
-
-
Verma, S.1
Miles, D.2
Gianni, L.3
-
27
-
-
80051751593
-
Phase I/II study of trastuzumab in combination with everolimus (RAD001) in patients with HER2-overexpressing metastatic breast cancer who progressed on trastuzumab-based therapy
-
Morrow P.K., Wulf G.M., Ensor J., et al. Phase I/II study of trastuzumab in combination with everolimus (RAD001) in patients with HER2-overexpressing metastatic breast cancer who progressed on trastuzumab-based therapy. JClin Oncol 2011, 29:3126-3132.
-
(2011)
JClin Oncol
, vol.29
, pp. 3126-3132
-
-
Morrow, P.K.1
Wulf, G.M.2
Ensor, J.3
-
28
-
-
78650984926
-
Phase I study of everolimus plus weekly paclitaxel and trastuzumab in patients with metastatic breast cancer pretreated with trastuzumab
-
Andre F., Campone M., O'Regan R., et al. Phase I study of everolimus plus weekly paclitaxel and trastuzumab in patients with metastatic breast cancer pretreated with trastuzumab. JClin Oncol 2010, 28:5110-5115.
-
(2010)
JClin Oncol
, vol.28
, pp. 5110-5115
-
-
Andre, F.1
Campone, M.2
O'Regan, R.3
-
29
-
-
78650967232
-
Phase I trial of oral mTOR inhibitor everolimus in combination with trastuzumab and vinorelbine in pre-treated patients with HER2-overexpressing metastatic breast cancer
-
Jerusalem G., Fasolo A., Dieras V., et al. Phase I trial of oral mTOR inhibitor everolimus in combination with trastuzumab and vinorelbine in pre-treated patients with HER2-overexpressing metastatic breast cancer. Breast Cancer Res Treat 2011, 125:447-455.
-
(2011)
Breast Cancer Res Treat
, vol.125
, pp. 447-455
-
-
Jerusalem, G.1
Fasolo, A.2
Dieras, V.3
-
30
-
-
80053402731
-
Human epidermal growth factor receptor 2-positive breast cancer relapsing post-adjuvant trastuzumab: pattern of recurrence, treatment and outcome
-
Krell J., James C.R., Shah D., et al. Human epidermal growth factor receptor 2-positive breast cancer relapsing post-adjuvant trastuzumab: pattern of recurrence, treatment and outcome. Clin Breast Cancer 2011, 11:153-160.
-
(2011)
Clin Breast Cancer
, vol.11
, pp. 153-160
-
-
Krell, J.1
James, C.R.2
Shah, D.3
-
31
-
-
84892477069
-
First results of a phase II study of bevacizumab in combination with trastuzumab and capecitabine as first-line treatment of HER2+ LA/MBC
-
abstract 571
-
Tjulandin S., Makhson A., Gligorov J., et al. First results of a phase II study of bevacizumab in combination with trastuzumab and capecitabine as first-line treatment of HER2+ LA/MBC. JClin Oncol 2011, 29(Suppl.). abstract 571.
-
(2011)
JClin Oncol
, vol.29
, Issue.SUPPL.
-
-
Tjulandin, S.1
Makhson, A.2
Gligorov, J.3
|