Meditative analgesia: The current state of the field

Annals of the New York Academy of Sciences

Volumn 1307, Issue 1, 2014, Pages 55-63

  Grant, Joshua A ^a  

^a MAX PLANCK INSTITUTE FOR HUMAN COGNITIVE AND BRAIN SCIENCES   (Germany)

Author keywords

Analgesia; Cognition; Emotion; Meditation; Mindfulness; Pain

Indexed keywords

ANALGESIA; ANALGESIC ACTIVITY; ANTICIPATION; ARTICLE; ATTENTION; EXPERIMENTAL PAIN; FOCUSED ATTENTION; HUMAN; LONGITUDINAL STUDY; MEDITATION; MINDFULNESS; MODULATION; MONITORING; NOCICEPTIVE STIMULATION; OPEN MONITORING; PAIN; PERSONAL EXPERIENCE;

ANALGESIA; COGNITION; EMOTION; MEDITATION; MINDFULNESS; PAIN;

ANALGESIA; ATTENTION; BRAIN; BRAIN MAPPING; BUDDHISM; COGNITION; EMPATHY; HUMANS; MEDITATION; MINDFULNESS; PAIN; PAIN MANAGEMENT; PAIN MEASUREMENT;

EID: 84892483426     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/nyas.12282     Document Type: Article

References (59)

1. Melzack, R. & K.L. Casey 1968. "Sensory, motivational, and central control determinants of pain." In The Skin Senses. D.R. Kenshalo, Ed.: 423-435. Springfield, IL: Thomas.
2. Apkarian, A.V. et al. 2005. Human brain mechanisms of pain perception and regulation in health and disease. Eur. J. Pain 9: 463-484.
3. Coghill, R.C. et al. 1999. Pain intensity processing within the human brain: a bilateral, distributed mechanism. J. Neurophysiol. 82: 1934-1943.
4. Rainville, P. et al. 1997. Pain affect encoded in human anterior cingulate but not somatosensory cortex. Science 277: 968-971.
5. Strigo, I.A. et al. 2003. Differentiation of visceral and cutaneous pain in the human brain. J. Neurophysiol. 89: 3294-3303.
6. Villemure, C. & M.C. Bushnell 2009. Mood influences supraspinal pain processing separately from attention. J. Neurosci. 29: 705-715.
7. Laverdure-Dupont, D. et al. 2009. Changes in rapid eye movement sleep associated with placebo-induced expectations and analgesia. J. Neurosci. 29: 11745-11752.
8. Ploghaus, A. et al. 2001. Exacerbation of pain by anxiety is associated with activity in a hippocampal network. J. Neurosci. 21: 9896-9903.
9. Fields, H.L. 2000. Pain modulation: expectation, opioid analgesia and virtual pain. Prog Brain Res. 122: 245-253.
10. May, A. & C. Gaser 2006. Magnetic resonance-based morphometry: a window into structural plasticity of the brain. Curr. Opin. Neurol. 19: 407-411.
11. Lutz, A. et al. 2008. Attention regulation and monitoring in meditation. Trends Cogn. Sci. 12: 163-169.
12. Travis, F. & J. Shear 2010. Focused attention, open monitoring and automatic self-transcending: categories to organize meditations from Vedic, Buddhist and Chinese traditions. Conscious Cogn. 19: 1110-1118.
13. Austin, J.H. 1999. Zen and the Brain: Toward an Understanding of Meditation and Consciousness. Cambridge, MA: MIT Press.
14. Zautra, A.J. et al. 2010. The effects of slow breathing on affective responses to pain stimuli: an experimental study. Pain 149: 12-18.
15. Jain, S. et al. 2007. A randomized controlled trial of mindfulness meditation versus relaxation training: effects on distress, positive states of mind, rumination, and distraction. Ann. Behav. Med. 33: 11-21.
16. Thibodeau, M.A. et al. 2013. Pain-related anxiety influences pain perception differently in men and women: a quantitative sensory test across thermal pain modalities. Pain 154: 419-426.
17. Corbetta, M. & G.L. Shulman 2002. Control of goal-directed and stimulus-driven attention in the brain. Nat. Rev. Neurosci. 3: 201-215.
18. Bushnell, M.C. et al. 1999. Pain perception: is there a role for primary somatosensory cortex? Proc. Natl. Acad. Sci. U. S. A. 96: 7705-7709.
19. Bantick, S.J. et al. 2002. Imaging how attention modulates pain in humans using functional MRI. Brain 125: 310-319.
20. Tracey, I. et al. 2002. Imaging attentional modulation of pain in the periaqueductal gray in humans. J. Neurosci. 22: 2748-2752.
21. Valet, M. et al. 2004. Distraction modulates connectivity of the cingulo-frontal cortex and the midbrain during pain-an fMRI analysis. Pain 109: 399-408.
22. Zeidan, F. et al. 2010. Mindfulness meditation improves cognition: evidence of brief mental training. Conscious Cogn. 19: 597-605.
23. Kakigi, R. et al. 2005. Intracerebral pain processing in a Yoga Master who claims not to feel pain during meditation. Eur. J. Pain 9: 581-589.
24. Grant, J.A. et al. 2013. Cortical thickness, mental absorption and meditative practice: possible implications for disorders of attention. Biol. Psychol. 92: 275-281.
25. Orme-Johnson, D.W. et al. 2006. Neuroimaging of meditation's effect on brain reactivity to pain. Neuroreport 17: 1359-1363.
26. Grant, J.A. & P. Rainville 2009. Pain sensitivity and analgesic effects of mindful states in Zen meditators: a cross-sectional study. Psychosom. Med. 71: 106-114.
27. Perlman, D.M. et al. 2010. Differential effects on pain intensity and unpleasantness of two meditation practices. Emotion 10: 65-71.
28. Holzel, B.K. et al. 2011. How does mindfulness meditation work? Proposing mechanisms of action from a conceptual and neural perspective. Perspect. Psychol. Sci. 537: 537-559.
29. Vago, D.R. & D.A. Silbersweig 2012. Self-awareness, self-regulation, and self-transcendence (S-ART): a framework for understanding the neurobiological mechanisms of mindfulness. Front. Hum. Neurosci. 6: 296.
30. Kingston, J. et al. 2007. A pilot randomized control trial investigating the effect of mindfulness practice on pain tolerance, psychological well-being, and physiological activity. J. Psychosom. Res. 62: 297-300.
31. Grant, J.A., J. Courtemanche & P. Rainville 2011. A non-elaborative mental stance and decoupling of executive and pain-related cortices predicts low pain sensitivity in Zen meditators. Pain 152: 150-156.
32. Gard, T. et al. 2012. Pain attenuation through mindfulness is associated with decreased cognitive control and increased sensory processing in the brain. Cereb. Cortex 11: 2692-2702.
33. Lutz, A. et al. 2013. Altered anterior insula activation during anticipation and experience of painful stimuli in expert meditators. Neuroimage 64: 538-546.
34. Rolls, E.T. 2008. Functions of the orbitofrontal and pregenual cingulate cortex in taste, olfaction, appetite and emotion. Acta. Physiol. Hung. 95: 131-164.
35. Suzuki, W.A. 2008. Associative learning signals in the brain. Prog. Brain Res. 169: 305-320.
36. Bechara, A., H. Damasio & A.R. Damasio 2003. Role of the amygdala in decision-making. Ann N.Y. Acad. Sci. 985: 356-369.
37. Ofen, N. et al. 2012. The development of brain systems associated with successful memory retrieval of scenes. J. Neurosci. 32: 10012-10020.
38. Mitchell, J.P. 2009. Inferences about mental states. Philos. Trans. R. Soc. Lond. B Biol. Sci. 364: 1309-1316.
39. Seeley, W.W. et al. 2007. Dissociable intrinsic connectivity networks for salience processing and executive control. J. Neurosci. 27: 2349-2356.
40. Wiech, K., M. Ploner & I. Tracey 2008. Neurocognitive aspects of pain perception. Trends Cogn. Sci. 12: 306-313.
41. Ochsner, K.N., J.A. Silvers & J.T. Buhle 2012. Functional imaging studies of emotion regulation: a synthetic review and evolving model of the cognitive control of emotion. Ann. N.Y. Acad. Sci. 1251: E1-E24.
42. Kerr, C.E. et al. 2013. Mindfulness starts with the body: somatosensory attention and top-down modulation of cortical alpha rhythms in mindfulness meditation. Front. Hum. Neurosci. 7: 12.
43. Taylor, V.A. et al. 2011. Impact of mindfulness on the neural responses to emotional pictures in experienced and beginner meditators. Neuroimage 57: 1524-1533.
44. Brewer, J.A., H.M. Elwafi & J.H. Davis 2013. Craving to quit: psychological models and neurobiological mechanisms of mindfulness training as treatment for addictions. Psychol. Addict. Behav. 27: 366-379.
45. Zeidan, F. et al. 2011. Brain mechanisms supporting the modulation of pain by mindfulness meditation. J. Neurosci. 31: 5540-5548.
46. Zeidan, F. et al. 2012. Mindfulness meditation-related pain relief: evidence for unique brain mechanisms in the regulation of pain. Neurosci. Lett. 520: 165-173.
47. Brown, C.A. & A.K. Jones 2010. Meditation experience predicts less negative appraisal of pain: electrophysiological evidence for the involvement of anticipatory neural responses. Pain 150: 428-438.
48. Tracey, I. & P.W. Mantyh 2007. The cerebral signature for pain perception and its modulation. Neuron 55: 377-391.
49. Depue, R.A. & J.V. Morrone-Strupinsky 2005. A neurobehavioral model of affiliative bonding: implications for conceptualizing a human trait of affiliation. Behav. Brain Sci. 28: 313-350; discussion 350-395.
50. Panksepp, J. et al. 1980. Endogenous opioids and social behavior. Neurosci. Biobehav. Rev. 4: 473-487.
51. Panksepp, J., E. Nelson & S. Siviy 1994. Brain opioids and mother-infant social motivation. Acta. Paediatr. Suppl. 397: 40-46.
52. Hein, G. et al. 2010. Neural responses to ingroup and outgroup members' suffering predict individual differences in costly helping. Neuron 68: 149-160.
53. Leiberg, S., O. Klimecki & T. Singer 2011. Short-term compassion training increases prosocial behavior in a newly developed prosocial game. PLoSOne 6: e17798.
54. Singer, T. et al. 2004. Empathy for pain involves the affective but not sensory components of pain. Science 303: 1157-1162.
55. Simon-Thomas, E.R. et al. 2011. An fMRI study of caring vs self-focus during induced compassion and pride. Soc. Cogn. Affect. Neurosci. 7: 635-648.
56. Klimecki, O.M. et al. 2013. Functional neural plasticity and associated changes in positive affect after compassion training. Cereb. Cortex 23: 1552-1561.
57. Grant, J.A. 2013. "Being with pain: a discussion of meditation-based analgesia." In Compassion: Bridging Practice and Science. A Multimedia Book. T. Singer & M. Bolz, Eds.; 252-269. Munich, Germany: Max Planck Society.
58. Brown, C.A. & A. Jones 2013. Psychobiological correlates of improved mental health in patients with musculoskeletal pain after a mindfulness-based pain management program. Clin. J. Pain 29: 233-244.
59. Grant, J.A. et al. 2010. Cortical thickness and pain sensitivity in Zen meditators. Emotion 10: 43-53.