-
1
-
-
79961046696
-
Diagnosis and management of stable chronic obstructive pulmonary disease: a clinical practice guideline update from the American College of Physicians, American College of Chest Physicians, American Thoracic Society, and European Respiratory Society
-
Qaseem A., Wilt T.J., Weinberger S.E., Hanania N.A., Criner G., van der Molen T., et al. Diagnosis and management of stable chronic obstructive pulmonary disease: a clinical practice guideline update from the American College of Physicians, American College of Chest Physicians, American Thoracic Society, and European Respiratory Society. Ann Intern Med 2011, 155:179-191.
-
(2011)
Ann Intern Med
, vol.155
, pp. 179-191
-
-
Qaseem, A.1
Wilt, T.J.2
Weinberger, S.E.3
Hanania, N.A.4
Criner, G.5
van der Molen, T.6
-
2
-
-
84873956600
-
Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease, GOLD executive summary
-
Vestbo J., Hurd S.S., Agusti A.G., Jones P.W., Vogelmeier C., Anzueto A., et al. Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease, GOLD executive summary. Am J Respir Crit Care Med 2013, 187:347-365.
-
(2013)
Am J Respir Crit Care Med
, vol.187
, pp. 347-365
-
-
Vestbo, J.1
Hurd, S.S.2
Agusti, A.G.3
Jones, P.W.4
Vogelmeier, C.5
Anzueto, A.6
-
3
-
-
84859424158
-
Chronic obstructive pulmonary disease
-
Decramer M., Janssens W., Miravitlles M. Chronic obstructive pulmonary disease. Lancet 2012, 379:1341-1351.
-
(2012)
Lancet
, vol.379
, pp. 1341-1351
-
-
Decramer, M.1
Janssens, W.2
Miravitlles, M.3
-
4
-
-
31844435204
-
Chronic obstructive pulmonary disease: current burden and future projections
-
Lopez A.D., Shibuya K., Rao C., Mathers C.D., Hansell A.L., Held L.S., et al. Chronic obstructive pulmonary disease: current burden and future projections. Eur Respir J 2006, 27:397-412.
-
(2006)
Eur Respir J
, vol.27
, pp. 397-412
-
-
Lopez, A.D.1
Shibuya, K.2
Rao, C.3
Mathers, C.D.4
Hansell, A.L.5
Held, L.S.6
-
5
-
-
80051893217
-
Clinical and economic burden of patients diagnosed with COPD with comorbid cardiovascular disease
-
Dalal A.A., Shah M., Lunacsek O., Hanania N.A. Clinical and economic burden of patients diagnosed with COPD with comorbid cardiovascular disease. Respir Med 2011, 105:1516-1522.
-
(2011)
Respir Med
, vol.105
, pp. 1516-1522
-
-
Dalal, A.A.1
Shah, M.2
Lunacsek, O.3
Hanania, N.A.4
-
6
-
-
57049135358
-
Inhaled corticosteroids in patients with stable chronic obstructive pulmonary disease: a systematic review and meta-analysis
-
Drummond M.B., Dasenbrook E.C., Pitz M.W., Murphy D.J., Fan E. Inhaled corticosteroids in patients with stable chronic obstructive pulmonary disease: a systematic review and meta-analysis. JAMA 2008, 300:2407-2416.
-
(2008)
JAMA
, vol.300
, pp. 2407-2416
-
-
Drummond, M.B.1
Dasenbrook, E.C.2
Pitz, M.W.3
Murphy, D.J.4
Fan, E.5
-
7
-
-
70350121951
-
Safety and efficacy of combined long-acting beta-agonists and inhaled corticosteroids vs long-acting beta-agonists monotherapy for stable COPD: a systematic review
-
Rodrigo G.J., Castro-Rodriguez J.A., Plaza V. Safety and efficacy of combined long-acting beta-agonists and inhaled corticosteroids vs long-acting beta-agonists monotherapy for stable COPD: a systematic review. Chest 2009, 136:1029-1038.
-
(2009)
Chest
, vol.136
, pp. 1029-1038
-
-
Rodrigo, G.J.1
Castro-Rodriguez, J.A.2
Plaza, V.3
-
8
-
-
53749102775
-
A 4-year trial of tiotropium in chronic obstructive pulmonary disease
-
Tashkin D.P., Celli B., Senn S., Burkhart D., Kesten S., Menjoge S., et al. A 4-year trial of tiotropium in chronic obstructive pulmonary disease. N Engl J Med 2008, 359:1543-1554.
-
(2008)
N Engl J Med
, vol.359
, pp. 1543-1554
-
-
Tashkin, D.P.1
Celli, B.2
Senn, S.3
Burkhart, D.4
Kesten, S.5
Menjoge, S.6
-
9
-
-
84892434544
-
Inhaled corticosteroid is associated with an increased risk of tuberculosis in patients with chronic obstructive pulmonary disease
-
[Epub ahead of print]
-
Kim J.H., Park J.S., Kim K.H., Jeong H.C., Kim E.K., Lee J.H. Inhaled corticosteroid is associated with an increased risk of tuberculosis in patients with chronic obstructive pulmonary disease. Chest 2012 Oct 20, [Epub ahead of print].
-
(2012)
Chest
-
-
Kim, J.H.1
Park, J.S.2
Kim, K.H.3
Jeong, H.C.4
Kim, E.K.5
Lee, J.H.6
-
10
-
-
77953105482
-
The preclinical pharmacology of roflumilast-a selective, oral phosphodiesterase 4 inhibitor in development for chronic obstructive pulmonary disease
-
Hatzelmann A., Morcillo E.J., Lungarella G., Adnot S., Sanjar S., Beume R., et al. The preclinical pharmacology of roflumilast-a selective, oral phosphodiesterase 4 inhibitor in development for chronic obstructive pulmonary disease. Pulm Pharmacol Ther 2010, 23:235-256.
-
(2010)
Pulm Pharmacol Ther
, vol.23
, pp. 235-256
-
-
Hatzelmann, A.1
Morcillo, E.J.2
Lungarella, G.3
Adnot, S.4
Sanjar, S.5
Beume, R.6
-
11
-
-
84864622679
-
-
Forest Pharmaceuticals, Inc, St. Louis, MO
-
Daliresp [package insert] 2011, Forest Pharmaceuticals, Inc, St. Louis, MO.
-
(2011)
Daliresp [package insert]
-
-
-
12
-
-
69149103642
-
Roflumilast in symptomatic chronic obstructive pulmonary disease: two randomised clinical trials
-
Calverley P.M., Rabe K.F., Goehring U.M., Kristiansen S., Fabbri L.M., Martinez F.J. Roflumilast in symptomatic chronic obstructive pulmonary disease: two randomised clinical trials. Lancet 2009, 374:685-694.
-
(2009)
Lancet
, vol.374
, pp. 685-694
-
-
Calverley, P.M.1
Rabe, K.F.2
Goehring, U.M.3
Kristiansen, S.4
Fabbri, L.M.5
Martinez, F.J.6
-
13
-
-
69149098943
-
Roflumilast in moderate-to-severe chronic obstructive pulmonary disease treated with longacting bronchodilators: two randomised clinical trials
-
Fabbri L.M., Calverley P.M., Izquierdo-Alonso J.L., Bundschuh D.S., Brose M., Martinez F.J., et al. Roflumilast in moderate-to-severe chronic obstructive pulmonary disease treated with longacting bronchodilators: two randomised clinical trials. Lancet 2009, 374:695-703.
-
(2009)
Lancet
, vol.374
, pp. 695-703
-
-
Fabbri, L.M.1
Calverley, P.M.2
Izquierdo-Alonso, J.L.3
Bundschuh, D.S.4
Brose, M.5
Martinez, F.J.6
-
14
-
-
79251588730
-
Reduction of exacerbations by the PDE4 inhibitor roflumilast-the importance of defining different subsets of patients with COPD
-
Rennard S.I., Calverley P.M., Goehring U.M., Bredenbroker D., Martinez F.J. Reduction of exacerbations by the PDE4 inhibitor roflumilast-the importance of defining different subsets of patients with COPD. Respir Res 2011, 12:18.
-
(2011)
Respir Res
, vol.12
, pp. 18
-
-
Rennard, S.I.1
Calverley, P.M.2
Goehring, U.M.3
Bredenbroker, D.4
Martinez, F.J.5
-
15
-
-
80155129530
-
Roflumilast in Asian patients with COPD: a randomized placebo-controlled trial
-
Lee S.D., Hui D.S., Mahayiddin A.A., Roa C.C., Kwa K.H., Goehring U.M., et al. Roflumilast in Asian patients with COPD: a randomized placebo-controlled trial. Respirology 2011, 16:1249-1257.
-
(2011)
Respirology
, vol.16
, pp. 1249-1257
-
-
Lee, S.D.1
Hui, D.S.2
Mahayiddin, A.A.3
Roa, C.C.4
Kwa, K.H.5
Goehring, U.M.6
-
16
-
-
84860473468
-
Physiological effects of roflumilast at rest and during exercise in COPD
-
O'Donnell D.E., Bredenbroker D., Brose M., Webb K.A. Physiological effects of roflumilast at rest and during exercise in COPD. Eur Respir J 2012, 39:1104-1112.
-
(2012)
Eur Respir J
, vol.39
, pp. 1104-1112
-
-
O'Donnell, D.E.1
Bredenbroker, D.2
Brose, M.3
Webb, K.A.4
-
17
-
-
23744451716
-
Roflumilast-an oral anti-inflammatory treatment for chronic obstructive pulmonary disease: a randomised controlled trial
-
Rabe K.F., Bateman E.D., O'Donnell D., Witte S., Bredenbroker D., Bethke T.D. Roflumilast-an oral anti-inflammatory treatment for chronic obstructive pulmonary disease: a randomised controlled trial. Lancet 2005, 366:563-571.
-
(2005)
Lancet
, vol.366
, pp. 563-571
-
-
Rabe, K.F.1
Bateman, E.D.2
O'Donnell, D.3
Witte, S.4
Bredenbroker, D.5
Bethke, T.D.6
-
18
-
-
34447310046
-
Effect of 1-year treatment with roflumilast in severe chronic obstructive pulmonary disease
-
Calverley P.M., Sanchez-Toril F., McIvor A., Teichmann P., Bredenbroeker D., Fabbri L.M. Effect of 1-year treatment with roflumilast in severe chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2007, 176:154-161.
-
(2007)
Am J Respir Crit Care Med
, vol.176
, pp. 154-161
-
-
Calverley, P.M.1
Sanchez-Toril, F.2
McIvor, A.3
Teichmann, P.4
Bredenbroeker, D.5
Fabbri, L.M.6
-
19
-
-
36749063803
-
Reduction in sputum neutrophil and eosinophil numbers by the PDE4 inhibitor roflumilast in patients with COPD
-
Grootendorst D.C., Gauw S.A., Verhoosel R.M., Sterk P.J., Hospers J.J., Bredenbroker D., et al. Reduction in sputum neutrophil and eosinophil numbers by the PDE4 inhibitor roflumilast in patients with COPD. Thorax 2007, 62:1081-1087.
-
(2007)
Thorax
, vol.62
, pp. 1081-1087
-
-
Grootendorst, D.C.1
Gauw, S.A.2
Verhoosel, R.M.3
Sterk, P.J.4
Hospers, J.J.5
Bredenbroker, D.6
-
20
-
-
79956098321
-
PDE4-inhibitors: a novel, targeted therapy for obstructive airways disease
-
Diamant Z., Spina D. PDE4-inhibitors: a novel, targeted therapy for obstructive airways disease. Pulm Pharmacol Ther 2011, 24:353-360.
-
(2011)
Pulm Pharmacol Ther
, vol.24
, pp. 353-360
-
-
Diamant, Z.1
Spina, D.2
-
21
-
-
84864552152
-
Roflumilast-a phosphodiesterase-4 inhibitor licensed for add-on therapy in severe COPD
-
Taegtmeyer A.B., Leuppi J.D., Kullak-Ublick G.A. Roflumilast-a phosphodiesterase-4 inhibitor licensed for add-on therapy in severe COPD. Swiss Med Wkly 2012, 142:w13628.
-
(2012)
Swiss Med Wkly
, vol.142
-
-
Taegtmeyer, A.B.1
Leuppi, J.D.2
Kullak-Ublick, G.A.3
-
22
-
-
84862290893
-
Selective PDE inhibitors as novel treatments for respiratory diseases
-
Page C.P., Spina D. Selective PDE inhibitors as novel treatments for respiratory diseases. Curr Opin Pharmacol 2012, 12:275-286.
-
(2012)
Curr Opin Pharmacol
, vol.12
, pp. 275-286
-
-
Page, C.P.1
Spina, D.2
-
25
-
-
68549101842
-
The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration
-
Liberati A., Altman D.G., Tetzlaff J., Mulrow C., Gotzsche P.C., Ioannidis J.P., et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. BMJ 2009, 339:b2700.
-
(2009)
BMJ
, vol.339
-
-
Liberati, A.1
Altman, D.G.2
Tetzlaff, J.3
Mulrow, C.4
Gotzsche, P.C.5
Ioannidis, J.P.6
-
27
-
-
11844307130
-
Roflumilast, a new, orally active phosphodiesterase 4 inhibitor, is effective in the treatment of chronic obstructive pulmonary disease
-
Bredenbroker D., Syed J., Leichtl S., Rathgeb F., Wurst W. Roflumilast, a new, orally active phosphodiesterase 4 inhibitor, is effective in the treatment of chronic obstructive pulmonary disease. Eur Respir J 2002, 20(Suppl. 38):374S.
-
(2002)
Eur Respir J
, vol.20
, Issue.SUPPL. 38
-
-
Bredenbroker, D.1
Syed, J.2
Leichtl, S.3
Rathgeb, F.4
Wurst, W.5
-
28
-
-
33646938884
-
The effect of rofiumilast treatment and subsequent withdrawal in patients with COPD
-
Boszormenyi-Nagy G., Pieters W.R., Steffen H., Timar M., Vinkler I., Teichmann P., et al. The effect of rofiumilast treatment and subsequent withdrawal in patients with COPD. Am J Respir Crit Care Med 2005, 169:A544.
-
(2005)
Am J Respir Crit Care Med
, vol.169
-
-
Boszormenyi-Nagy, G.1
Pieters, W.R.2
Steffen, H.3
Timar, M.4
Vinkler, I.5
Teichmann, P.6
-
29
-
-
20144382361
-
Minimal clinically important differences in COPD lung function
-
Donohue J.F. Minimal clinically important differences in COPD lung function. COPD 2005, 2:111-124.
-
(2005)
COPD
, vol.2
, pp. 111-124
-
-
Donohue, J.F.1
-
30
-
-
20144385478
-
Minimal clinically important difference-exacerbations of COPD
-
Calverley P.M. Minimal clinically important difference-exacerbations of COPD. COPD 2005, 2:143-148.
-
(2005)
COPD
, vol.2
, pp. 143-148
-
-
Calverley, P.M.1
-
31
-
-
21544475914
-
Pulmonary rehabilitation in chronic obstructive pulmonary disease
-
Troosters T., Casaburi R., Gosselink R., Decramer M. Pulmonary rehabilitation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2005, 172:19-38.
-
(2005)
Am J Respir Crit Care Med
, vol.172
, pp. 19-38
-
-
Troosters, T.1
Casaburi, R.2
Gosselink, R.3
Decramer, M.4
-
32
-
-
20144362569
-
St. George's respiratory questionnaire: MCID
-
Jones P.W. St. George's respiratory questionnaire: MCID. COPD 2005, 2:75-79.
-
(2005)
COPD
, vol.2
, pp. 75-79
-
-
Jones, P.W.1
-
33
-
-
84873661428
-
Efficacy and safety of roflumilast in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis
-
Oba Y., Lone N.A. Efficacy and safety of roflumilast in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis. Ther Adv Respir Dis 2013, 7:13-24.
-
(2013)
Ther Adv Respir Dis
, vol.7
, pp. 13-24
-
-
Oba, Y.1
Lone, N.A.2
-
34
-
-
84871373004
-
Effect of tiotropium vs. salmeterol on exacerbations: GOLD II and maintenance therapy naive patients
-
Vogelmeier C., Fabbri L.M., Rabe K.F., Beeh K.M., Schmidt H., Metzdorf N., et al. Effect of tiotropium vs. salmeterol on exacerbations: GOLD II and maintenance therapy naive patients. Respir Med 2013, 107:75-83.
-
(2013)
Respir Med
, vol.107
, pp. 75-83
-
-
Vogelmeier, C.1
Fabbri, L.M.2
Rabe, K.F.3
Beeh, K.M.4
Schmidt, H.5
Metzdorf, N.6
-
35
-
-
0037425745
-
Combined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease: a randomised controlled trial
-
Calverley P., Pauwels R., Vestbo J., Jones P., Pride N., Gulsvik A., et al. Combined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease: a randomised controlled trial. Lancet 2003, 361:449-456.
-
(2003)
Lancet
, vol.361
, pp. 449-456
-
-
Calverley, P.1
Pauwels, R.2
Vestbo, J.3
Jones, P.4
Pride, N.5
Gulsvik, A.6
-
36
-
-
84883558031
-
Efficacy of roflumilast in the chronic obstructive pulmonary disease frequent exacerbator phenotype
-
[Epub ahead of print]
-
Wedzicha J.A., Rabe K.F., Martinez F.J., Bredenbroker D., Brose M., Goehring U.M., et al. Efficacy of roflumilast in the chronic obstructive pulmonary disease frequent exacerbator phenotype. Chest 2012 Nov 3, [Epub ahead of print].
-
(2012)
Chest
-
-
Wedzicha, J.A.1
Rabe, K.F.2
Martinez, F.J.3
Bredenbroker, D.4
Brose, M.5
Goehring, U.M.6
-
37
-
-
34547191725
-
A 1-year prospective cost-effectiveness analysis of roflumilast for the treatment of patients with severe chronic obstructive pulmonary disease
-
Rutten-van Molken M.P., van Nooten F.E., Lindemann M., Caeser M., Calverley P.M. A 1-year prospective cost-effectiveness analysis of roflumilast for the treatment of patients with severe chronic obstructive pulmonary disease. Pharmacoeconomics 2007, 25:695-711.
-
(2007)
Pharmacoeconomics
, vol.25
, pp. 695-711
-
-
Rutten-van Molken, M.P.1
van Nooten, F.E.2
Lindemann, M.3
Caeser, M.4
Calverley, P.M.5
-
38
-
-
84864826489
-
Drug safety in COPD revisited: what is the number needed to analyzeα
-
Rabe K.F. Drug safety in COPD revisited: what is the number needed to analyzeα. Chest 2012, 142:271-274.
-
(2012)
Chest
, vol.142
, pp. 271-274
-
-
Rabe, K.F.1
-
39
-
-
84860306689
-
Cost-effectiveness of available treatment options for patients suffering from severe COPD in the UK: a fully incremental analysis
-
Hertel N., Kotchie R.W., Samyshkin Y., Radford M., Humphreys S., Jameson K. Cost-effectiveness of available treatment options for patients suffering from severe COPD in the UK: a fully incremental analysis. Int J Chron Obstruct Pulmon Dis 2012, 7:183-199.
-
(2012)
Int J Chron Obstruct Pulmon Dis
, vol.7
, pp. 183-199
-
-
Hertel, N.1
Kotchie, R.W.2
Samyshkin, Y.3
Radford, M.4
Humphreys, S.5
Jameson, K.6
|