Predictive value of thrombus attenuation on thin-slice non-contrast CT for persistent occlusion after intravenous thrombolysis

Cerebrovascular Diseases

Volumn 37, Issue 2, 2014, Pages 116-122

  Niesten, J M ^a   Van Der Schaaf, I C ^a   Van Der Graaf, Y ^a   Kappelle, L J ^a   Biessels, G J ^a   Horsch, A D ^a   Dankbaar, J W ^a   Luitse, M J A ^a   Van Seeters, T ^a   Smit, E J ^a   Mali, W P Th M ^a   Velthuis, B K ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Attenuation; CT; IV rtPA; Recanalization; Stroke

Indexed keywords

ALTEPLASE;

AGED; ARTICLE; BLOOD CLOT LYSIS; COMPUTED TOMOGRAPHY SCANNER; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; FEMALE; FOLLOW UP; HUMAN; INTERNAL CAROTID ARTERY OCCLUSION; MAJOR CLINICAL STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NON CONTRAST COMPUTER ASSISTED TOMOGRAPHY; OCCLUSIVE CEREBROVASCULAR DISEASE; PREDICTIVE VALUE; PRIORITY JOURNAL; RECANALIZATION; BRAIN INFARCTION; BRAIN ISCHEMIA; COMPUTED TOMOGRAPHIC ANGIOGRAPHY; DENSITY; OCCLUSION; THIN SLICE NON CONTRAST COMPUTER ASSISTED TOMOGRAPHY; THROMBUS;

ADULT; AGED; AGED, 80 AND OVER; FEMALE; HUMANS; INTRACRANIAL THROMBOSIS; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; STROKE; THROMBOLYTIC THERAPY; THROMBOSIS; TISSUE PLASMINOGEN ACTIVATOR; TOMOGRAPHY, X-RAY COMPUTED; TREATMENT OUTCOME;

EID: 84892411339     PISSN: 10159770     EISSN: 14219786     Source Type: Journal    
DOI: 10.1159/000357420     Document Type: Article

References (40)

1. Rha JH, Saver JL: The impact of recanalization on ischemic stroke outcome: a meta-analysis. Stroke 2007; 38:967-973.
2. Saver JL: Time is brain-quantified. Stroke 2006; 37:263-266.
3. Mazighi M, Serfaty JM, Labreuche J, Laissy JP, Meseguer E, Lavallee PC, Cabrejo L, Slaoui T, Guidoux C, Lapergue B, Klein IF, Olivot JM, Abboud H, Simon O, Niclot P, Nifle C, Touboul PJ, Raphaeli G, Gohin C, Claeys ES, Amarenco P: Comparison of intravenous alteplase with a combined intra-venous-endovascular approach in patients with stroke and confirmed arterial occlusion (RECANALISE study): a prospective cohort study. Lancet Neurol 2009; 8: 802-809.
4. Jang IK, Gold HK, Ziskind AA, Fallon JT, Holt RE, Leinbach RC, May JW, Collen D: Differential sensitivity of erythrocyte-rich and platelet-rich arterial thrombi to lysis with recombinant tissue-type plasminogen activator. A possible explanation for resistance to coronary thrombolysis. Circulation 1989; 79: 920-928.
5. Caplan LR: Antiplatelet therapy in stroke prevention: present and future. Cerebrovasc Dis 2006; 21(suppl 1):1-6.
6. Kim EY, Lee SK, Kim DJ, Suh SH, Kim J, Heo JH, Kim DI: Detection of thrombus in acute ischemic stroke: value of thin-section non-contrast-computed tomography. Stroke 2005; 36:2745-2747.
7. Riedel CH, Zoubie J, Ulmer S, Gierthmuehlen J, Jansen O: Thin-slice reconstructions of nonenhanced CT images allow for detection of thrombus in acute stroke. Stroke 2012; 43: 2319-2323.
8. Nam HS, Kim EY, Kim SH, Kim YD, Kim J, Lee HS, Nam CM, Heo JH: Prediction of thrombus resolution after intravenous thrombolysis assessed by CT-based thrombus imaging. Thromb Haemost 2012; 107:786-794.
9. Kim EY, Heo JH, Lee SK, Kim DJ, Suh SH, Kim J, Kim DI: Prediction of thrombolytic efficacy in acute ischemic stroke using thin-section noncontrast CT. Neurology 2006; 67: 1846-1848.
10. Moulin T, Tatu L, Vuillier F, Cattin F: Brain CT scan for acute cerebral infarction: early signs of ischemia (in French). Rev Neurol (Paris) 1999; 155:649-655.
11. Kirchhof K, Welzel T, Mecke C, Zoubaa S, Sartor K: Differentiation of white, mixed, and red thrombi: value of CT in estimation of the prognosis of thrombolysis phantom study. Radiology 2003; 228:126-130.
12. Adams HP Jr, Bendixen BH, Kappelle LJ, Bill-er J, Love BB, Gordon DL, Marsh EE 3rd: Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. Toast. Trial of Org 10172 in Acute Stroke Treatment. Stroke 1993; 24:35-41.
13. Chen CJ, Tseng YC, Lee TH, Hsu HL, See LC: Multisection CT angiography compared with catheter angiography in diagnosing vertebral artery dissection. AJNR Am J Neuroradiol 2004; 25:769-774.
14. Kim YK, Schulman S: Cervical artery dissection: pathology, epidemiology and management. Thromb Res 2009; 123:810-821.
15. Puetz V, Dzialowski I, Hill MD, Subramani-am S, Sylaja PN, Krol A, O'Reilly C, Hudon ME, Hu WY, Coutts SB, Barber PA, Watson T, Roy J, Demchuk AM: Intracranial thrombus extent predicts clinical outcome, final in-farct size and hemorrhagic transformation in ischemic stroke: the clot burden score. Int J Stroke 2008; 3:230-236.
16. Tomsick T, Broderick J, Carrozella J, Khatri P, Hill M, Palesch Y, Khoury J: Revasculariza-tion results in the Interventional Management of Stroke II trial. AJNR Am J Neurora-diol 2008; 29:582-587.
17. Yoo AJ, Simonsen CZ, Prabhakaran S, Chaudhry ZA, Issa MA, Fugate JE, Linfante I, Liebeskind DS, Khatri P, Jovin TG, Kallmes DF, Dabus G, Zaidat OO: Refining angio-graphic biomarkers of revascularization: improving outcome prediction after intra-arte-rial therapy. Stroke 2013; 44:2509-2512.
18. Barreto AD, Albright KC, Hallevi H, Grotta JC, Noser EA, Khaja AM, Shaltoni HM, Gon-zales NR, Illoh K, Martin-Schild S, Campbell MS 3rd, Weir RU, Savitz SI: Thrombus burden is associated with clinical outcome after intra-arterial therapy for acute ischemic stroke. Stroke 2008; 39:3231-3235.
19. Saqqur M, Uchino K, Demchuk AM, Molina CA, Garami Z, Calleja S, Akhtar N, Orouk FO, Salam A, Shuaib A, Alexandrov AV: Site of arterial occlusion identified by transcranial Doppler predicts the response to intravenous thrombolysis for stroke. Stroke 2007; 38:948-954.
20. Murphy A, Symons SP, Hopyan J, Aviv RI: Factors influencing clinically meaningful re-canalization after IV-rtPA in acute ischemic stroke. AJNR Am J Neuroradiol 2013; 34:146-152.
21. Molina CA, Alexandrov AV, Demchuk AM, Saqqur M, Uchino K, Alvarez-Sabin J: Improving the predictive accuracy of recanaliza-tion on stroke outcome in patients treated with tissue plasminogen activator. Stroke 2004; 35:151-156.
22. Kimura K, Iguchi Y, Shibazaki K, Aoki J, Watanabe M, Matsumoto N, Yamashita S: Early stroke treatment with IV t-PA associated with early recanalization. J Neurol Sci 2010; 295:53-57.
23. Swets JA: Measuring the accuracy of diagnostic systems. Science 1988; 240:1285-1293.
24. DeLong ER, DeLong DM, Clarke-Pearson DL: Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics 1988; 44:837-845.
25. Puig J, Pedraza S, Demchuk A, Daunis IEJ, Termes H, Blasco G, Soria G, Boada I, Re-mollo S, Banos J, Serena J, Castellanos M: Quantification of thrombus Hounsfield units on noncontrast CT predicts stroke subtype and early recanalization after intravenous recombinant tissue plasminogen activator. AJNR Am J Neuroradiol 2012; 33: 90-96.
26. Moftakhar P, English JD, Cooke DL, Kim WT, Stout C, Smith WS, Dowd CF, Higashida RT, Halbach VV, Hetts SW: Density of thrombus on admission CT predicts revascu-larization efficacy in large vessel occlusion acute ischemic stroke. Stroke 2013; 44:243-245.
27. Yilmaz U, Roth C, Reith W, Papanagiotou P: Thrombus attenuation does not predict an-giographic results of mechanical thrombec-tomy with stent retrievers. AJNR Am J Neu-roradiol 2013; 34:2184-2186.
28. Ahmed N, Wahlgren N, Grond M, Hennerici M, Lees KR, Mikulik R, Parsons M, Roine RO, Toni D, Ringleb P: Implementation and outcome of thrombolysis with alteplase 3-4.5 h after an acute stroke: an updated analysis from SITS-ISTR. Lancet Neurol 2010; 9:866-874.
29. Yeo LL, Paliwal P, Teoh HL, Seet RC, Chan BP, Liang S, Venketasubramanian N, Rathakrishnan R, Ahmad A, Ng KW, Loh PK, Ong JJ, Wakerley BR, Chong VF, Bathla G, Sharma VK: Timing of recanalization after intravenous thrombolysis and functional outcomes after acute ischemic stroke. JAMA Neurol 2013; 70:353-358.
30. Niesten JM, van der Schaaf IC, Biessels GJ, van Otterloo AE, van Seeters T, Horsch AD, Luitse MJ, van der Graaf Y, Kappelle LJ, Mali WP, Velthuis BK: Relationship between thrombus attenuation and different stroke subtypes. Neuroradiology 2013; 55:1071-1079.
31. Cho KH, Lee DH, Kwon SU, Choi CG, Kim SJ, Suh DC, Kim JS, Kang DW: Factors and outcomes associated with recanalization timing after thrombolysis. Cerebrovasc Dis 2012; 33:255-261.
32. Molina CA, Montaner J, Arenillas JF, Ribo M, Rubiera M, Alvarez-Sabin J: Differential pattern of tissue plasminogen activator-induced proximal middle cerebral artery recanaliza-tion among stroke subtypes. Stroke 2004; 35: 486-490.
33. Rocha S, Pires A, Gomes J, Rocha J, Sousa F, Pinho J, Rodrigues M, Ferreira C, Machado A, Mare R, Fontes JR: Intravenous thrombolysis is more effective in ischemic cardioembolic strokes than in non-cardioembolic? Arq Neu-ropsiquiatr 2011; 69:905-909.
34. Hsia AW, Sachdev HS, Tomlinson J, Hamilton SA, Tong DC: Efficacy of IV tissue plas-minogen activator in acute stroke: does stroke subtype really matter? Neurology 2003; 61: 71-75.
35. Riedel CH, Zimmermann P, Jensen-Konder-ing U, Stingele R, Deuschl G, Jansen O: The importance of size: successful recanalization by intravenous thrombolysis in acute anterior stroke depends on thrombus length. Stroke 2011; 42:1775-1777.
36. Ernst R, Pancioli A, Tomsick T, Kissela B, Woo D, Kanter D, Jauch E, Carrozzella J, Spilker J, Broderick J: Combined intravenous and intra-arterial recombinant tissue plas-minogen activator in acute ischemic stroke. Stroke 2000; 31:2552-2557.
37. Tandberg Askevold E, Naess H, Thomassen L: Predictors for recanalization after intravenous thrombolysis in acute ischemic stroke. J Stroke Cerebrovasc Dis 2007; 16: 21-24.
38. Roberts HC, Dillon WP, Furlan AJ, Wechsler LR, Rowley HA, Fischbein NJ, Higashida RT, Kase C, Schulz GA, Lu Y, Firszt CM: Computed tomographic findings in patients undergoing intra-arterial thromboly-sis for acute ischemic stroke due to middle cerebral artery occlusion-results from the PROACT II trial. Stroke 2002; 33: 1557-1565.
39. Manelfe C, Larrue V, von Kummer R, Bozzao L, Ringleb P, Bastianello S, Iweins F, Lesaffre E: Association of hyperdense middle cerebral artery sign with clinical outcome in patients treated with tissue plasminogen activator. Stroke 1999; 30:769-772.
40. Fitzsimmons PR, Biswas S, Hill AM, Kumar R, Cullen C, White RP, Sharma AK, Durairaj R: The hyperdense internal carotid artery sign: prevalence and prognostic relevance in stroke thrombolysis. Stroke Res Treat 2011; 2011:843607.