Expression of estrogen receptor α and β in esophageal squamous cell carcinoma

Oncology Reports

Volumn 30, Issue 6, 2013, Pages 2771-2776

  Dong, Jing ^a   Jiang, Shi Wen ^a,c   Niu, Yanru ^a   Chen, Ling ^a   Liu, Shuyan ^a   Ma, Tianzhong ^a   Chen, Xiancai ^a   Xu, Liyan ^a,b   Su, Zhongjing ^a   Chen, Haibin ^a,b  

^a SHANTOU UNIVERSITY MEDICAL COLLEGE   (China)

^b Key Laboratory of Oncomolecular Biology in Chaoshan Littoral Area   (China)

^c MERCER UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Esophageal carcinoma; Estrogen receptor; Histopathology; Immunohistochemistry

Indexed keywords

ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA;

ADULT; AGE; ARTICLE; CANCER GRADING; CANCER PATIENT; CANCER PROGNOSIS; CORRELATION ANALYSIS; CORRELATION COEFFICIENT; DOWN REGULATION; EPITHELIUM; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; FEMALE; GENDER; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; KAPLAN MEIER METHOD; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; TUMOR CLASSIFICATION; TUMOR INVASION; TUMOR VOLUME; UPREGULATION;

AGED; CARCINOMA, SQUAMOUS CELL; ESOPHAGEAL NEOPLASMS; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; NEOPLASM GRADING; PROGNOSIS;

EID: 84892410053     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2013.2770     Document Type: Article

References (28)

1. Jemal A, Bray F, Center MM, Ferlay J, Ward E and Forman D: Global cancer statistics. CA Cancer J Clin 61: 69-90, 2011.
2. Sugimachi K, Matsuoka H, Matsufuji H, Maekawa S, Kai H and Okudaira Y: Survival rates of women with carcinoma of the esophagus exceed those of men. Surg Gynecol Obstet 164: 541-544, 1987.
3. Matsuoka H, Sugimachi K, Ueo H, Kuwano H, Nakano S and Nakayama M: Sex hormone response of a newly established squamous cell line derived from clinical esophageal carcinoma. Cancer Res 47: 4134-4140, 1987.
4. Ueo H, Matsuoka H, Sugimachi K, Kuwano H, Mori M and Akiyoshi T: Inhibitory effects of estrogen on the growth of a human esophageal carcinoma cell line. Cancer Res 50: 7212-7215, 1990.
5. Derakhshan MH, Liptrot S, Paul J, Brown IL, Morrison D and McColl KE: Oesophageal and gastric intestinal-type adenocarcinomas show the same male predominance due to a 17 year delayed development in females. Gut 58: 16-23, 2009.
6. Niikawa H, Suzuki T, Miki Y, et al: Intratumoral estrogens and estrogen receptors in human non-small cell lung carcinoma. Clin Cancer Res 14: 4417-4426, 2008.
7. Mauro LV, Dalurzo M, Carlini MJ, et al: Estrogen receptor β and epidermal growth factor receptor as early-stage prognostic biomarkers of non-small cell lung cancer. Oncol Rep 24: 1331-1338, 2010.
8. Teng J, Wang ZY, Jarrard DF and Bjorling DE: Roles of estrogen receptor alpha and beta in modulating urothelial cell proliferation. Endocr Relat Cancer 15: 351-364, 2008.
9. Rath-Wolfson L, Purim O, Ram E, Morgenstern S, Koren R and Brenner B: Expression of estrogen receptor β1 in colorectal cancer: Correlation with clinicopathological variables. Oncol Rep 27: 2017-2022, 2012.
10. Hogan AM, Collins D, Baird AW and Winter DC: Estrogen and gastrointestinal malignancy. Mol Cell Endocrinol 307: 19-24, 2009.
11. Woo IS, Park MJ, Choi SW, et al: Loss of estrogen receptor-α expression is associated with hypermethylation near its ATG start codon in gastric cancer cell lines. Oncol Rep 11: 617-622, 2004.
12. Peng B, Lu B, Leygue E and Murphy LC: Putative functional characteristics of human estrogen receptor-beta isoforms. J Mol Endocrinol 30: 13-29, 2003.
13. Utsumi Y, Nakamura T, Nagasue N, Kubota H and Morikawa S: Role of estrogen receptors in the growth of human esophageal carcinoma. Cancer 64: 88-93, 1989.
14. Utsumi Y, Nakamura T, Nagasue N, Kubota H, Harada T and Morikawa S: Effect of 17 beta-estradiol on the growth of an estrogen receptor-positive human esophageal carcinoma cell line. Cancer 67: 2284-2289, 1991.
15. Nozoe T, Oyama T, Takenoyama M, Hanagiri T, Sugio K and Yasumoto K: Significance of immunohistochemical expression of estrogen receptors alpha and beta in squamous cell carcinoma of the esophagus. Clin Cancer Res 13: 4046-4050, 2007.
16. Kalayarasan R, Ananthakrishnan N, Kate V and Basu D: Estrogen and progesterone receptors in esophageal carcinoma. Dis Esophagus 21: 298-303, 2008.
17. Wang QM, Yuan L, Qi YJ, Ma ZY and Wang LD: Estrogen analogues: promising target for prevention and treatment of esophageal squamous cell carcinoma in high risk areas. Med Sci Monit 16: HY19-HY22, 2010.
18. Zuguchi M, Miki Y, Onodera Y, et al: Estrogen receptor alpha and beta in esophageal squamous cell carcinoma. Cancer Sci 103: 1348-1355, 2012.
19. Yang H, Sukocheva OA, Hussey DJ and Watson DI: Estrogen, male dominance and esophageal adenocarcinoma: is there a link? World J Gastroenterol 18: 393-400, 2012.
20. Wang QM, Qi YJ, Jiang Q, Ma YF and Wang LD: Relevance of serum estradiol and estrogen receptor beta expression from a high-incidence area for esophageal squamous cell carcinoma in China. Med Oncol 28: 188-193, 2011.
21. McDonnell DP and Norris JD: Connections and regulation of the human estrogen receptor. Science 296: 1642-1644, 2002.
22. Kawai H, Ishii A, Washiya K, et al: Estrogen receptor alpha and beta are prognostic factors in non-small cell lung cancer. Clin Cancer Res 11: 5084-5089, 2005.
23. Liu S, Zhu N and Chen H: Expression patterns of human DAB2IP protein in fetal tissues. Biotech Histochem 87: 350-359, 2012.
24. Bredfeldt TG, Greathouse KL, Safe SH, Hung MC, Bedford MT and Walker CL: Xenoestrogen-induced regulation of EZH2 and histone methylation via estrogen receptor signaling to PI3K/AKT. Mol Endocrinol 24: 993-1006, 2010.
25. He LR, Liu MZ, Li BK, et al: Prognostic impact of H3K27me3 expression on locoregional progression after chemoradiotherapy in esophageal squamous cell carcinoma. BMC Cancer 9: 461, 2009.
26. He LR, Liu MZ, Li BK, et al: High expression of EZH2 is associated with tumor aggressiveness and poor prognosis in patients with esophageal squamous cell carcinoma treated with definitive chemoradiotherapy. Int J Cancer 127: 138-147, 2010.
27. Zhao G, Nie Y, Lv M, et al: ERbeta-mediated estradiol enhances epithelial mesenchymal transition of lung adenocarcinoma through increasing transcription of midkine. Mol Endocrinol 26: 1304-1315, 2012.
28. Zhao G, Zhao S, Wang T, Zhang S, Lu K, Yu L and Hou Y: Estrogen receptor beta signaling regulates the progression of Chinese non-small cell lung cancer. J Steroid Biochem Mol Biol 124: 47-57, 2011.