메뉴 건너뛰기




Volumn 23, Issue 2, 2014, Pages 145-148

Prospects for new antibacterials: Can we do better?

Author keywords

Antibacterial development; Carbapenem resistant enterobacteria; Efflux pumps; Hospital acquired infections; Inactivating enzymes; Multiresistant bacteria; New antibacterials; New targets

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANTIBIOTIC AGENT; CARBAPENEM DERIVATIVE; CEPHALOSPORIN DERIVATIVE; FOLIC ACID ANTAGONIST; GLYCOPEPTIDE; KETOLIDE; OXAZOLIDINONE DERIVATIVE; TELITHROMYCIN;

EID: 84892393378     PISSN: 13543784     EISSN: 17447658     Source Type: Journal    
DOI: 10.1517/13543784.2014.847087     Document Type: Review
Times cited : (7)

References (25)
  • 1
    • 59449088862 scopus 로고    scopus 로고
    • Antibioticresistant bugs in the 21st century-A clinical super-challenge
    • Arias CA, Murray BE. Antibioticresistant bugs in the 21st century-a clinical super-challenge. N Engl J Med 2009;360:439-43
    • (2009) N Engl J Med , vol.360 , pp. 439-443
    • Arias, C.A.1    Murray, B.E.2
  • 2
    • 57749107808 scopus 로고    scopus 로고
    • Bad bugs, no drugs: No ESKAPE! An update from the Infectious Diseases Society of America
    • Boucher HW, Talbot GH, Bradley JS, et al. Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America. Clin Infect Dis 2009; 48:1-12
    • (2009) Clin Infect Dis , vol.48 , pp. 1-12
    • Boucher, H.W.1    Talbot, G.H.2    Bradley, J.S.3
  • 3
    • 70349446050 scopus 로고    scopus 로고
    • The changing epidemiology of resistance
    • Hawkey PM, Jones AM. The changing epidemiology of resistance. J Antimicrob Chemother 2009; 64(Suppl 1):i3-10
    • (2009) J Antimicrob Chemother , vol.64 , Issue.SUPPL. 1
    • Hawkey, P.M.1    Jones, A.M.2
  • 5
    • 60549087911 scopus 로고    scopus 로고
    • Plan to combat extensively drug-resistant tuberculosis: Recommendations of the Federal Tuberculosis Task Force
    • Centers for Disease Control and Prevention (CDC)
    • Centers for Disease Control and Prevention (CDC). Plan to combat extensively drug-resistant tuberculosis: recommendations of the Federal Tuberculosis Task Force. MMWR Recomm Rep 2009;58(RR-3):1-43
    • (2009) MMWR Recomm Rep , vol.58 , pp. 1-43
  • 6
    • 33846696731 scopus 로고    scopus 로고
    • Community-associated methicillin-resistant Staphylococcus aureus isolates causing healthcare-associated infections
    • Maree CL, Daum RS, Boyle-Vavra S, et al. Community-associated methicillinresistant Staphylococcus aureus isolates and healthcare-associated infections. Emerg Infect Dis 2007;13:236-42 (Pubitemid 46193166)
    • (2007) Emerging Infectious Diseases , vol.13 , Issue.2 , pp. 236-242
    • Maree, C.L.1    Daum, R.S.2    Boyle-Vavra, S.3    Matayoshi, K.4    Miller, L.G.5
  • 8
    • 84878850292 scopus 로고    scopus 로고
    • Increasing prevalence of carbapenem-resistant Enterobacteriaceae and strategies to avert a looming crisis
    • Watkins RR, Bonomo RA. Increasing prevalence of carbapenem-resistant Enterobacteriaceae and strategies to avert a looming crisis. Expert Rev Anti Infect Ther 2013;11:543-5
    • (2013) Expert Rev Anti Infect Ther , vol.11 , pp. 543-545
    • Watkins, R.R.1    Bonomo, R.A.2
  • 9
    • 84874586090 scopus 로고    scopus 로고
    • Investigation of antibiotic resistance in the genomic era of multidrug-resistant Gram-negative bacilli, especially Enterobacteriaceae, Pseudomonas and Acinetobacter
    • Diene SM, Rolain JM. Investigation of antibiotic resistance in the genomic era of multidrug-resistant Gram-negative bacilli, especially Enterobacteriaceae, Pseudomonas and Acinetobacter. Expert Rev Anti Infect Ther 2013; 11:277-96
    • (2013) Expert Rev Anti Infect Ther , vol.11 , pp. 277-296
    • Diene, S.M.1    Rolain, J.M.2
  • 10
    • 84881045151 scopus 로고    scopus 로고
    • In vitro sensitivity of Acinetobacter baumannii and Pseudomonas aeruginosa to carbapenems among intensive care unit patients
    • Guzek A, Korzeniewski K, Nitsch-Osuch A, et al. In vitro sensitivity of Acinetobacter baumannii and Pseudomonas aeruginosa to carbapenems among intensive care unit patients. Adv Exp Med Biol 2013;788:109-16
    • (2013) Adv Exp Med Biol , vol.788 , pp. 109-116
    • Guzek, A.1    Korzeniewski, K.2    Nitsch-Osuch, A.3
  • 11
    • 34347407844 scopus 로고    scopus 로고
    • Clostridium difficile: Changing epidemiology and new treatment options
    • DOI 10.1097/QCO.0b013e32818be71d, PII 0000143220070800000006
    • Kuijper EJ, van Dissel JT, Wilcox MH. Clostridium difficile: changing epidemiology and new treatment options. Curr Opin Infect Dis 2007;20:376-83 (Pubitemid 47026234)
    • (2007) Current Opinion in Infectious Diseases , vol.20 , Issue.4 , pp. 376-383
    • Kuijper, E.J.1    Van Dissel, J.T.2    Wilcox, M.H.3
  • 12
    • 84873038467 scopus 로고    scopus 로고
    • Fecal microbiota transplantation-an old therapy comes of age
    • Kelly CP. Fecal microbiota transplantation-an old therapy comes of age. N Engl J Med 2013;368:474-5
    • (2013) N Engl J Med , vol.368 , pp. 474-475
    • Kelly, C.P.1
  • 13
    • 27844473756 scopus 로고    scopus 로고
    • Outlook: The profit problem in antibiotic R&D
    • DOI 10.1038/nrd1878, PII N1878
    • Nathan C, Goldberg FM. Outlook: the profit problem in antibiotic R&D. Nat Rev Drug Discov 2005;4:887-91 (Pubitemid 41637690)
    • (2005) Nature Reviews Drug Discovery , vol.4 , Issue.11 , pp. 887-891
    • Nathan, C.1    Goldberg, F.M.2
  • 14
    • 79952427389 scopus 로고    scopus 로고
    • Preserving the lifesaving power of antimicrobial agents
    • Hughes JM. Preserving the lifesaving power of antimicrobial agents. JAMA 2011;305:1027-8
    • (2011) JAMA , vol.305 , pp. 1027-1028
    • Hughes, J.M.1
  • 15
    • 35748958975 scopus 로고    scopus 로고
    • Late stage antibacterial drugs in the clinical pipeline
    • DOI 10.1016/j.mib.2007.08.007, PII S1369527407001221, Antimicrobials/Genomics
    • Projan SJ, Bradford PA. Late stage antibacterial drugs in the clinical pipeline. Curr Opin Microbiol 2007;10:441-6 (Pubitemid 350052689)
    • (2007) Current Opinion in Microbiology , vol.10 , Issue.5 , pp. 441-446
    • Projan, S.J.1    Bradford, P.A.2
  • 16
    • 84864387245 scopus 로고    scopus 로고
    • Adverse effects of antimicrobials via predictable or idiosyncratic inhibition of host mitochondrial components
    • Barnhill AE, Brewer MT, Carlson SA. Adverse effects of antimicrobials via predictable or idiosyncratic inhibition of host mitochondrial components. Antimicrob Agents Chemother 2012;56:4046-51
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 4046-4051
    • Barnhill, A.E.1    Brewer, M.T.2    Carlson, S.A.3
  • 17
    • 58949090373 scopus 로고    scopus 로고
    • Telithromycin-associated hepatotoxicity: Clinical spectrum and causality assessment of 42 cases
    • Brinker AD, Wassel RT, Lyndly J, et al. Telithromycin-associated hepatotoxicity: clinical spectrum and causality assessment of 42 cases. Hepatology 2009;49:250-7
    • (2009) Hepatology , vol.49 , pp. 250-257
    • Brinker, A.D.1    Wassel, R.T.2    Lyndly, J.3
  • 18
    • 84861406845 scopus 로고    scopus 로고
    • Eosinophilic pneumonia in patients treated with daptomycin: Review of the literature and US FDA adverse event reporting system reports
    • Kim PW, Sorbello AF, Wassel RT, et al. Eosinophilic pneumonia in patients treated with daptomycin: review of the literature and US FDA adverse event reporting system reports. Drug Saf 2012;35(6):447-57
    • (2012) Drug Saf , vol.35 , Issue.6 , pp. 447-457
    • Kim, P.W.1    Sorbello, A.F.2    Wassel, R.T.3
  • 19
    • 40949099893 scopus 로고    scopus 로고
    • New antibacterial agents for treating infections caused by multi-drug resistant gram-negative bacteria
    • DOI 10.1517/13543784.17.3.297
    • O'Neill AJ. New antibacterial agents for treating infections caused by multi-drug resistant Gram-negative bacteria. Expert Opin Investig Drugs 2008;17: 297-302 (Pubitemid 351578182)
    • (2008) Expert Opinion on Investigational Drugs , vol.17 , Issue.3 , pp. 297-302
    • O'Neill, A.J.1
  • 20
    • 55249125476 scopus 로고    scopus 로고
    • Potential of old-generation antibiotics to address current need for new antibiotics
    • Falagas ME, Grammatikos AP, Michalopoulos A. Potential of old-generation antibiotics to address current need for new antibiotics. Expert Rev Anti Infect Ther 2008;6: 593-600
    • (2008) Expert Rev Anti Infect Ther , vol.6 , pp. 593-600
    • Falagas, M.E.1    Grammatikos, A.P.2    Michalopoulos, A.3
  • 21
    • 84889582557 scopus 로고    scopus 로고
    • Health care-associated infections: A meta-analysis of costs and financial impact on the US health care system
    • Published online September 02
    • Zimlichman E, Henderson D, Tamir O, et al. Health care-associated infections: a meta-analysis of costs and financial impact on the US health care system. JAMA Intern Med; Published online September 02, 2013
    • (2013) JAMA Intern Med
    • Zimlichman, E.1    Henderson, D.2    Tamir, O.3
  • 22
    • 84880790088 scopus 로고    scopus 로고
    • The price of drugs for chronic myeloid leukemia (CML) is a reflection of the unsustainable prices of cancer drugs: From the perspective of a large group of CML experts
    • Experts in Chronic Myeloid Leukemia (119)
    • Experts in Chronic Myeloid Leukemia (119). The price of drugs for chronic myeloid leukemia (CML) is a reflection of the unsustainable prices of cancer drugs: from the perspective of a large group of CML experts. Blood 2013; 121:4439-42
    • (2013) Blood , vol.121 , pp. 4439-4442
  • 23
    • 65249146929 scopus 로고    scopus 로고
    • Multidrug resistance in bacteria
    • Nikaido H. Multidrug resistance in bacteria. Annu Rev Biochem 2009; 78:119-46
    • (2009) Annu Rev Biochem , vol.78 , pp. 119-146
    • Nikaido, H.1
  • 24
    • 84255195549 scopus 로고    scopus 로고
    • Understanding the regulatory hurdles for antibacterial drug development in the post-Ketek world
    • Echols RM. Understanding the regulatory hurdles for antibacterial drug development in the post-Ketek world. Ann NY Acad Sci 2011;1241:153-61
    • (2011) Ann NY Acad Sci , vol.1241 , pp. 153-161
    • Echols, R.M.1
  • 25
    • 84874238564 scopus 로고    scopus 로고
    • A comprehensive regulatory framework to address the unmet need for new antibacterial treatments
    • Rex JH, Eisenstein BI, Alder J, et al. A comprehensive regulatory framework to address the unmet need for new antibacterial treatments. Lancet Infect Dis 2013;13:269-75
    • (2013) Lancet Infect Dis , vol.13 , pp. 269-275
    • Rex, J.H.1    Eisenstein, B.I.2    Alder, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.