Rationale and design of a randomized, double-blind, placebo controlled multicenter trial to study efficacy, security, and long term effects of intermittent repeated levosimendan administration in patients with advanced heart failure: LAICA study

Cardiovascular Drugs and Therapy

Volumn 27, Issue 6, 2013, Pages 573-579

  García González, Martín J ^a   De Mora Martín, Manuel ^b   López Fernández, Silvia ^c   López Díaz, Javier ^d   Martínez Sellés, Manuel ^e   Romero García, José ^f   Cordero, Marco ^a   Lara Padrón, Antonio ^a   Marrero Rodríguez, Francisco ^a   Del Mar Garcia Saiz M ^a   Aldea Perona, Ana ^a  

^a HOSPITAL UNIVERSITARIO DE CANARIAS   (Spain)

^b HOSPITAL REGIONAL UNIVERSITARIO DE MÁLAGA   (Spain)

^c HOSPITAL UNIVERSITARIO VIRGEN DE LAS NIEVES   (Spain)

^d HOSPITAL CLÍNICO UNIVERSITARIO DE VALLADOLID   (Spain)

^e HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

^f Hospital UniversitarioFundación Jiménez Díaz   (Spain)

Author keywords

Advanced heart failure; Efficacy; Levosimendan; Outpatients; Repeated administration; Safety

Indexed keywords

LEVOSIMENDAN; PLACEBO;

ADULT; AGED; ARTICLE; CONTINUOUS INFUSION; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; FOLLOW UP; HEART FAILURE; HOSPITAL ADMISSION; HUMAN; INFORMATION PROCESSING; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MORTALITY; MULTICENTER STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SAMPLE SIZE; VERY ELDERLY; YOUNG ADULT;

CARDIOTONIC AGENTS; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; HEART FAILURE; HOSPITALIZATION; HUMANS; HYDRAZONES; PYRIDAZINES;

EID: 84892368263     PISSN: 09203206     EISSN: 15737241     Source Type: Journal    
DOI: 10.1007/s10557-013-6476-7     Document Type: Article

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