-
2
-
-
84875223342
-
PTEN losses exhibit heterogeneity in multifocal prostatic adenocarcinoma and are associated with higher Gleason grade
-
Yoshimoto M, Ding K, Sweet JM, Ludkovski O, Trottier G, et al. (2013) PTEN losses exhibit heterogeneity in multifocal prostatic adenocarcinoma and are associated with higher Gleason grade. Mod Pathol 26: 435-447.
-
(2013)
Mod Pathol
, vol.26
, pp. 435-447
-
-
Yoshimoto, M.1
Ding, K.2
Sweet, J.M.3
Ludkovski, O.4
Trottier, G.5
-
3
-
-
79953038262
-
PTEN loss in the continuum of common cancers, rare syndromes and mouse models
-
Hollander MC, Blumenthal GM, Dennis PA (2011) PTEN loss in the continuum of common cancers, rare syndromes and mouse models. Nat Rev Cancer 11: 289-301.
-
(2011)
Nat Rev Cancer
, vol.11
, pp. 289-301
-
-
Hollander, M.C.1
Blumenthal, G.M.2
Dennis, P.A.3
-
4
-
-
66749188650
-
Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate
-
Carver BS, Tran J, Gopalan A, Chen Z, Shaikh S, et al. (2009) Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate. Nat Genet 41: 619-624.
-
(2009)
Nat Genet
, vol.41
, pp. 619-624
-
-
Carver, B.S.1
Tran, J.2
Gopalan, A.3
Chen, Z.4
Shaikh, S.5
-
5
-
-
84859416889
-
Pten loss and RAS/MAPK activation cooperate to promote EMT and metastasis initiated from prostate cancer stem/progenitor cells
-
Mulholland DJ, Kobayashi N, Ruscetti M, Zhi A, Tran LM, et al. (2012) Pten loss and RAS/MAPK activation cooperate to promote EMT and metastasis initiated from prostate cancer stem/progenitor cells. Cancer Res 72: 1878-1889.
-
(2012)
Cancer Res
, vol.72
, pp. 1878-1889
-
-
Mulholland, D.J.1
Kobayashi, N.2
Ruscetti, M.3
Zhi, A.4
Tran, L.M.5
-
6
-
-
84864365646
-
JNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostate
-
Hubner A, Mulholland DJ, Standen CL, Karasarides M, Cavanagh-Kyros J, et al. (2012) JNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostate. Proc Natl Acad Sci U S A 109: 12046-12051.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 12046-12051
-
-
Hubner, A.1
Mulholland, D.J.2
Standen, C.L.3
Karasarides, M.4
Cavanagh-Kyros, J.5
-
7
-
-
66149141021
-
PTEN and the PI3-kinase pathway in cancer
-
Chalhoub N, Baker SJ (2009) PTEN and the PI3-kinase pathway in cancer. Annu Rev Pathol 4: 127-150.
-
(2009)
Annu Rev Pathol
, vol.4
, pp. 127-150
-
-
Chalhoub, N.1
Baker, S.J.2
-
9
-
-
77954890370
-
PTEN and TRP53 independently suppress Nanog expression in spermatogonial stem cells
-
Kuijk EW, van Mil A, Brinkhof B, Penning LC, Colenbrander B, et al. (2010) PTEN and TRP53 independently suppress Nanog expression in spermatogonial stem cells. Stem Cells Dev 19: 979-988.
-
(2010)
Stem Cells Dev
, vol.19
, pp. 979-988
-
-
Kuijk, E.W.1
Van Mil, A.2
Brinkhof, B.3
Penning, L.C.4
Colenbrander, B.5
-
10
-
-
77955329636
-
Plzf regulates germline progenitor self-renewal by opposing mTORC1
-
Hobbs RM, Seandel M, Falciatori I, Rafii S, Pandolfi PP (2010) Plzf regulates germline progenitor self-renewal by opposing mTORC1. Cell 142: 468-479.
-
(2010)
Cell
, vol.142
, pp. 468-479
-
-
Hobbs, R.M.1
Seandel, M.2
Falciatori, I.3
Rafii, S.4
Pandolfi, P.P.5
-
11
-
-
41849128523
-
The FoxO code
-
DOI 10.1038/onc.2008.21, PII ONC200821
-
Calnan DR, Brunet A (2008) The FoxO code. Oncogene 27: 2276-2288. (Pubitemid 351501779)
-
(2008)
Oncogene
, vol.27
, Issue.16
, pp. 2276-2288
-
-
Calnan, D.R.1
Brunet, A.2
-
12
-
-
49849093007
-
Unravelling the tumor-suppressive functions of FOXO proteins
-
Dansen TB, Burgering BM (2008) Unravelling the tumor-suppressive functions of FOXO proteins. Trends Cell Biol 18: 421-429.
-
(2008)
Trends Cell Biol
, vol.18
, pp. 421-429
-
-
Dansen, T.B.1
Burgering, B.M.2
-
13
-
-
17144430994
-
KIP1 promoter transactivation
-
DOI 10.1158/1541-7786.MCR-04-0163
-
Lynch RL, Konicek BW, McNulty AM, Hanna KR, Lewis JE, et al. (2005) The progression of LNCaP human prostate cancer cells to androgen independence involves decreased FOXO3a expression and reduced p27KIP1 promoter transactivation. Mol Cancer Res 3: 163-169. (Pubitemid 40524899)
-
(2005)
Molecular Cancer Research
, vol.3
, Issue.3
, pp. 163-169
-
-
Lynch, R.L.1
Konicek, B.W.2
McNulty, A.M.3
Hanna, K.R.4
Lewis, J.E.5
Neubauer, B.L.6
Graff, J.R.7
-
14
-
-
80455176679
-
Applications of post-translational modifications of FoxO family proteins in biological functions
-
Zhao Y, Wang Y, Zhu WG (2011) Applications of post-translational modifications of FoxO family proteins in biological functions. J Mol Cell Biol 3: 276-282.
-
(2011)
J Mol Cell Biol
, vol.3
, pp. 276-282
-
-
Zhao, Y.1
Wang, Y.2
Zhu, W.G.3
-
15
-
-
79251536870
-
PTEN genomic deletion is an early event associated with ERG gene rearrangements in prostate cancer
-
Bismar TA, Yoshimoto M, Vollmer RT, Duan Q, Firszt M, et al. (2011) PTEN genomic deletion is an early event associated with ERG gene rearrangements in prostate cancer. BJU Int 107: 477-485.
-
(2011)
BJU Int
, vol.107
, pp. 477-485
-
-
Bismar, T.A.1
Yoshimoto, M.2
Vollmer, R.T.3
Duan, Q.4
Firszt, M.5
-
16
-
-
84864716473
-
Copy number alterations of c-MYC and PTEN are prognostic factors for relapse after prostate cancer radiotherapy
-
Zafarana G, Ishkanian AS, Malloff CA, Locke JA, Sykes J, et al. (2012) Copy number alterations of c-MYC and PTEN are prognostic factors for relapse after prostate cancer radiotherapy. Cancer 118: 4053-4062.
-
(2012)
Cancer
, vol.118
, pp. 4053-4062
-
-
Zafarana, G.1
Ishkanian, A.S.2
Malloff, C.A.3
Locke, J.A.4
Sykes, J.5
-
17
-
-
79953803691
-
PTEN deletion and heme oxygenase-1 overexpression cooperate in prostate cancer progression and are associated with adverse clinical outcome
-
Li Y, Su J, DingZhang X, Zhang J, Yoshimoto M, et al. (2011) PTEN deletion and heme oxygenase-1 overexpression cooperate in prostate cancer progression and are associated with adverse clinical outcome. J Pathol 224: 90-100.
-
(2011)
J Pathol
, vol.224
, pp. 90-100
-
-
Li, Y.1
Su, J.2
DingZhang, X.3
Zhang, J.4
Yoshimoto, M.5
-
18
-
-
33747842237
-
Interphase FISH analysis of PTEN in histologic sections shows genomic deletions in 68% of primary prostate cancer and 23% of high-grade prostatic intra-epithelial neoplasias
-
DOI 10.1016/j.cancergencyto.2006.04.003, PII S0165460806002524
-
Yoshimoto M, Cutz JC, Nuin PA, Joshua AM, Bayani J, et al. (2006) Interphase FISH analysis of PTEN in histologic sections shows genomic deletions in 68% of primary prostate cancer and 23% of high-grade prostatic intra-epithelial neoplasias. Cancer Genet Cytogenet 169: 128-137. (Pubitemid 44287105)
-
(2006)
Cancer Genetics and Cytogenetics
, vol.169
, Issue.2
, pp. 128-137
-
-
Yoshimoto, M.1
Cutz, J.-C.2
Nuin, P.A.S.3
Joshua, A.M.4
Bayani, J.5
Evans, A.J.6
Zielenska, M.7
Squire, J.A.8
-
19
-
-
77949652932
-
The promyelocytic leukemia zinc-finger gene, PLZF, is frequently downregulated in malignant mesothelioma cells and contributes to cell survival
-
Cheung M, Pei J, Pei Y, Jhanwar SC, Pass HI, et al. (2010) The promyelocytic leukemia zinc-finger gene, PLZF, is frequently downregulated in malignant mesothelioma cells and contributes to cell survival. Oncogene 29: 1633-1640.
-
(2010)
Oncogene
, vol.29
, pp. 1633-1640
-
-
Cheung, M.1
Pei, J.2
Pei, Y.3
Jhanwar, S.C.4
Pass, H.I.5
-
20
-
-
33745310485
-
PLZF regulates Pbx1 transcription and Pbx1-HoxC8 complex leads to androgen-independent prostate cancer proliferation
-
DOI 10.1002/pros.20443
-
Kikugawa T, Kinugasa Y, Shiraishi K, Nanba D, Nakashiro K, et al. (2006) PLZF regulates Pbx1 transcription and Pbx1-HoxC8 complex leads to androgen-independent prostate cancer proliferation. Prostate 66: 1092-1099. (Pubitemid 43939214)
-
(2006)
Prostate
, vol.66
, Issue.10
, pp. 1092-1099
-
-
Kikugawa, T.1
Kinugasa, Y.2
Shiraishi, K.3
Nanba, D.4
Nakashiro, K.-I.5
Tanji, N.6
Yokoyama, M.7
Higashiyama, S.8
-
21
-
-
84879207760
-
The promyelocytic leukemia zinc finger protein: Two decades of molecular oncology
-
Suliman BA, Xu D, Williams BR (2012) The promyelocytic leukemia zinc finger protein: two decades of molecular oncology. Front Oncol 2: 74.
-
(2012)
Front Oncol
, vol.2
, pp. 74
-
-
Suliman, B.A.1
Xu, D.2
Williams, B.R.3
-
22
-
-
0001281430
-
Leukemia translocation protein PLZF inhibits cell growth and expression of cyclin A
-
DOI 10.1038/sj.onc.1202375
-
Yeyati PL, Shaknovich R, Boterashvili S, Li J, Ball HJ, et al. (1999) Leukemia translocation protein PLZF inhibits cell growth and expression of cyclin A. Oncogene 18: 925-934. (Pubitemid 29086269)
-
(1999)
Oncogene
, vol.18
, Issue.4
, pp. 925-934
-
-
Yeyati, P.L.1
Shaknovich, R.2
Boterashvili, S.3
Li, J.4
Ball, H.J.5
Waxman, S.6
Nason-Burchenal, K.7
Dmitrovsky, E.8
Zelent, A.9
Licht, J.D.10
-
23
-
-
0344629425
-
Growth Suppression by Acute Promyelocytic Leukemia-Associated Protein PLZF Is Mediated by Repression of c-myc Expression
-
DOI 10.1128/MCB.23.24.9375-9388.2003
-
McConnell MJ, Chevallier N, Berkofsky-Fessler W, Giltnane JM, Malani RB, et al. (2003) Growth suppression by acute promyelocytic leukemia-associated protein PLZF is mediated by repression of c-myc expression. Mol Cell Biol 23: 9375-9388. (Pubitemid 37499823)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.24
, pp. 9375-9388
-
-
McConnell, M.J.1
Chevallier, N.2
Berkofsky-Fessler, W.3
Giltnane, J.M.4
Malani, R.B.5
Staudt, L.M.6
Licht, J.D.7
-
24
-
-
34748862280
-
Repression of kit expression by Plzf in germ cells
-
DOI 10.1128/MCB.00479-07
-
Filipponi D, Hobbs RM, Ottolenghi S, Rossi P, Jannini EA, et al. (2007) Repression of kit expression by Plzf in germ cells. Mol Cell Biol 27: 6770-6781. (Pubitemid 47483628)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.19
, pp. 6770-6781
-
-
Filipponi, D.1
Hobbs, R.M.2
Ottolenghi, S.3
Rossi, P.4
Jannini, E.A.5
Pandolfi, P.P.6
Dolci, S.7
-
25
-
-
13044286010
-
Genomic sequence, structural organization, molecular evolution, and aberrant rearrangement of promyelocytic leukemia zinc finger gene
-
DOI 10.1073/pnas.96.20.11422
-
Zhang T, Xiong H, Kan LX, Zhang CK, Jiao XF, et al. (1999) Genomic sequence, structural organization, molecular evolution, and aberrant rearrangement of promyelocytic leukemia zinc finger gene. Proc Natl Acad Sci U S A 96: 11422-11427. (Pubitemid 29487396)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.20
, pp. 11422-11427
-
-
Zhang, T.1
Xiong, H.2
Kan, L.-X.3
Zhang, C.-K.4
Jiao, X.-F.5
Fu, G.6
Zhang, Q.-H.7
Lu, L.8
Tong, J.-H.9
Gu, B.-W.10
Yu, M.11
Liu, J.-X.12
Licht, J.13
Waxman, S.14
Zelent, A.15
Chen, E.16
Chen, S.-J.17
-
26
-
-
0033582929
-
Akt promotes cell survival by phosphorylating and inhibiting a forkhead transcription factor
-
Brunet A, Bonni A, Zigmond MJ, Lin MZ, Juo P, et al. (1999) Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 96: 857-868. (Pubitemid 29165088)
-
(1999)
Cell
, vol.96
, Issue.6
, pp. 857-868
-
-
Brunet, A.1
Bonni, A.2
Zigmond, M.J.3
Lin, M.Z.4
Juo, P.5
Hu, L.S.6
Anderson, M.J.7
Arden, K.C.8
Blenis, J.9
Greenberg, M.E.10
-
27
-
-
0027411688
-
Fusion between a novel Kruppel-like zinc finger gene and the retinoic acid receptor-alpha locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemia
-
Chen Z, Brand NJ, Chen A, Chen SJ, Tong JH, et al. (1993) Fusion between a novel Kruppel-like zinc finger gene and the retinoic acid receptor-alpha locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemia. EMBO J 12: 1161-1167. (Pubitemid 23095865)
-
(1993)
EMBO Journal
, vol.12
, Issue.3
, pp. 1161-1167
-
-
Chen, Z.1
Brand, N.J.2
Chen, A.3
Chen, S.-J.4
Tong, J.-H.5
Wang, Z.-Y.6
Waxman, S.7
Zelent, A.8
-
28
-
-
0034123470
-
Plzf regulates limb and axial skeletal patterning
-
DOI 10.1038/76014
-
Barna M, Hawe N, Niswander L, Pandolfi PP (2000) Plzf regulates limb and axial skeletal patterning. Nat Genet 25: 166-172. (Pubitemid 30394986)
-
(2000)
Nature Genetics
, vol.25
, Issue.2
, pp. 166-172
-
-
Barna, M.1
Hawe, N.2
Lee, N.3
Pandolfi, P.P.4
-
29
-
-
14844318507
-
The promyelotic leukemia zinc finger promotes osteoblastic differentiation of human mesenchymal stem cells as an upstream regulator of CBFA1
-
DOI 10.1074/jbc.M409442200
-
Ikeda R, Yoshida K, Tsukahara S, Sakamoto Y, Tanaka H, et al. (2005) The promyelotic leukemia zinc finger promotes osteoblastic differentiation of human mesenchymal stem cells as an upstream regulator of CBFA1. J Biol Chem 280: 8523-8530. (Pubitemid 40349757)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.9
, pp. 8523-8530
-
-
Ikeda, R.1
Yoshida, K.2
Tsukahara, S.3
Sakamoto, Y.4
Tanaka, H.5
Furukawa, K.-I.6
Inoue, I.7
-
30
-
-
2642522727
-
Plzf is required in adult male germ cells for stem cell self-renewal
-
DOI 10.1038/ng1366
-
Buaas FW, Kirsh AL, Sharma M, McLean DJ, Morris JL, et al. (2004) Plzf is required in adult male germ cells for stem cell self-renewal. Nat Genet 36: 647-652. (Pubitemid 38715995)
-
(2004)
Nature Genetics
, vol.36
, Issue.6
, pp. 647-652
-
-
Buaas, F.W.1
Kirsh, A.L.2
Sharma, M.3
McLean, D.J.4
Morris, J.L.5
Griswold, M.D.6
De Rooij, D.G.7
Braun, R.E.8
-
31
-
-
42349087828
-
The promyelocytic leukemia zinc finger-microRNA-221/-222 pathway controls melanoma progression through multiple oncogenic mechanisms
-
DOI 10.1158/0008-5472.CAN-07-2538
-
Felicetti F, Errico MC, Bottero L, Segnalini P, Stoppacciaro A, et al. (2008) The promyelocytic leukemia zinc finger-microRNA-221/-222 pathway controls melanoma progression through multiple oncogenic mechanisms. Cancer Res 68: 2745-2754. (Pubitemid 351556272)
-
(2008)
Cancer Research
, vol.68
, Issue.8
, pp. 2745-2754
-
-
Felicetti, F.1
Errico, M.C.2
Bottero, L.3
Segnalini, P.4
Stoppacciaro, A.5
Biffoni, M.6
Felli, N.7
Mattia, G.8
Petrini, M.9
Colombo, M.P.10
Peschle, C.11
Care, A.12
-
32
-
-
20744456118
-
Histone acetyltransferase activity of p300 is required for transcriptional repression by the promyelocytic leukemia zinc finger protein
-
DOI 10.1128/MCB.25.13.5552-5566.2005
-
Guidez F, Howell L, Isalan M, Cebrat M, Alani RM, et al. (2005) Histone acetyltransferase activity of p300 is required for transcriptional repression by the promyelocytic leukemia zinc finger protein. Mol Cell Biol 25: 5552-5566. (Pubitemid 40853590)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.13
, pp. 5552-5566
-
-
Guidez, F.1
Howell, L.2
Isalan, M.3
Cebrat, M.4
Alani, R.M.5
Ivins, S.6
Hormaeche, I.7
McConnell, M.J.8
Pierce, S.9
Cole, P.A.10
Licht, J.11
Zelent, A.12
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