Adjuvant volumetric-modulated arc therapy with simultaneous integrated boost in endometrial cancer. Planning and toxicity comparison

Acta Oncologica

Volumn 53, Issue 2, 2014, Pages 251-258

  Macchia, Gabriella ^a   Cilla, Savino ^a   Morganti, Alessio Giuseppe ^a,b   Deodato, Francesco ^a   Legge, Francesco ^a   Piermattei, Angelo ^a   Chiantera, Vito ^a   Scambia, Giovanni ^b   Valentini, Vincenzo ^b   Ferrandina, Gabriella ^a,b  

^a CATHOLIC UNIVERSITY   (Italy)

^b FONDAZIONE POLICLINICO UNIVERSITARIO A GEMELLI IRCCS   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; BLADDER CAPACITY; BODY MASS; CANCER ADJUVANT THERAPY; CANCER RADIOTHERAPY; CANCER STAGING; COMPARATIVE STUDY; COMPUTER ASSISTED RADIOTHERAPY; DIARRHEA; ENDOMETRIUM CANCER; HUMAN; INTENSITY MODULATED RADIATION THERAPY; LEUKOPENIA; LYMPH NODE DISSECTION; MAJOR CLINICAL STUDY; MIDDLE AGED; ORGANS AT RISK; PELVIS LYMPH NODE; PELVIS LYMPHADENECTOMY; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROSPECTIVE STUDY; RADIATION DOSE; RADIATION INJURY; RECTUM; SKIN TOXICITY; SMALL INTESTINE; TREATMENT PLANNING; VERY ELDERLY; ACUTE TOXICITY; ANEMIA; BLEEDING; CLINICAL ARTICLE; CONFORMITY INDEX; CONTROLLED STUDY; DOSIMETRY; DYSURIA; FEMALE; GASTROINTESTINAL TOXICITY; GENITOURINARY TOXICITY; INTERMEDIATE RISK PATIENT; PLANNING TARGET VOLUME; POSTOPERATIVE CARE; RADIATION DOSE DISTRIBUTION; SIMULTANEOUS INTEGRATED BOOST VOLUMETRIC MODULATED ARC THERAPY; STATISTICAL PARAMETERS; TENESMUS; THREE DIMENSIONAL CONFORMAL RADIOTHERAPY; URINARY FREQUENCY; URINARY URGENCY; VAGINA; VAGINAL VAULT;

ADULT; AGED; AGED, 80 AND OVER; ENDOMETRIAL NEOPLASMS; FEMALE; HUMANS; MIDDLE AGED; ORGANS AT RISK; RADIOTHERAPY DOSAGE; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RADIOTHERAPY, INTENSITY-MODULATED;

EID: 84892161403     PISSN: 0284186X     EISSN: 1651226X     Source Type: Journal    
DOI: 10.3109/0284186X.2013.819997     Document Type: Article

References (25)

1. NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) . Uterine Neoplasms Version 3. 2012 . NCCN.org
2. Creutzberg CL, v an Putten WL, K oper PC , L ybeert ML , Jobsen JJ , W á rl á m-Rodenhuis CC , et al . Surgery and postoperative radiotherapy versus surgery alone for patients with stage-1 endometrial carcinoma: Multicentre randomised trial . PORTEC Study Group. Post Operative Radiation Therapy in Endometrial Carcinoma. Lancet 2000 ; 355 : 1404-11
3. Lauve A , M orris M , S chmidt-Ullrich R , W u Q, M ohan R , Abayomi O , et al . Simultaneous integrated boost intensitymodulated radiotherapy for locally advanced head-and-neck squamous cell carcinomas: II-clinical results . Int J Radiat Oncol Biol Phys 2004 ; 60 : 374-87
4. Mundt AJ , M ell LK, R oeske JC . P reliminary analysis of chronic gastrointestinal toxicity in gynecology patients treated with intensity-modulated whole pelvic radiation therapy . Int J Radiat Oncol Biol Phys 2003 ; 56 : 1354-60
5. Tierney RM , Powell MA , M utch DG , G ibb RK , R ader JS , Grigsby PW . Acute toxicity of postoperative IMRT and chemotherapy for endometrial cancer . Radiat Med 2007 ; 25 : 439-45
6. Shih K K, M ilgrom S A , A bu-Rustum N R , K ollmeier MA , Gardner GJ , Tew WP , et al . Postoperative pelvic intensitymodulated radiotherapy in high risk endometrial cancer . Gynecol Oncol 2013 ; 128 : 535-9
7. Jhingran A , W inter K, P ortelance L, M iller BE, S alehpour MR , Gaur R , et al . Effi cacy and safety of IMRT after surgery in patients with endometrial cancer: RTOG 0418 phase II study . Int J Radiat Oncol Biol Phys 2011 ; 81 : S45
8. Otto K . V olumetric modulated arc therapy: IMRT in a single gantry arc . Med Phys 2008 ; 35 : 310-7
9. Aznar MC , P etersen PM , L ogadottir A , L indberg H, Korreman SS , Kjr-Kristoffersen F , et al . Rotational radiotherapy for prostate cancer in clinical practice . Radiother Oncol 2010 ; 97 : 480-4
10. Cilla S , C aravatta L, P icardi V , S abatino D , M acchia G , Diges ù C , et al . Volumetric modulated arc therapy with simultaneous integrated boost for locally advanced rectal cancer . Clin Oncol (R Coll Radiol) 2012 ; 24 : 261-8
11. Yang R , J iang W, W ang J . A novel conformal arc technique for postoperative whole pelvic radiotherapy for endometrial cancer . Int J Gynecol Cancer 2009 ; 19 : 1574-9
12. Macchia G , F errandina G , D eodato F , B ibb ò R , M assaccesi M , Ippolito E , et al . 3D conformal postoperative radiotherapy with concomitant boost in uterine cancer: Results of a phase I-II study (ADA-RT-1) . Gynecol Oncol 2011 ; 120 : 485-8
13. Weiss E, H irnle P , A rnold-Bofi nger H, H ess CF, Bamberg M . Therapeutic outcome and relation of acute and late side effects in the adjuvant radiotherapy of endometrial carcinoma stage I and II . Radiother Oncol 1999 ; 53 : 37-44
14. Cilla S , M acchia G , D iges ù C, D eodato F , S abatino D , Morganti AG , et al . Endocavitary in vivo dosimetry for IMRT treatments of gynecologic tumors . Med Dosim 2011 ; 36 : 455-62
15. Cilla S , M acchia G , S abatino D , D iges ù C, D eodato F , Piermattei A , et al . Applicator-guided volumetric-modulated arc therapy for low-risk endometrial cancer . Med Dosim 2013 ; 38 : 5-15
16. Macchia G , C illa S , F errandina G , P adula GD , D eodato F , Diges ù C , et al . Postoperative intensity-modulated radiotherapy in low-risk endometrial cancers: Final results of a Phase I study . Int J Radiat Oncol Biol Phys 2010 ; 76 : 1390-5
17. Small Jr W , M ell L K, A nderson P , C reutzberg C , D e Los Santos J , Gaffney D , et al . Consensus guidelines for delineation of clinical target volume for intensity-modulated pelvic radiotherapy in postoperative treatment of endometrial and cervical cancer . Int J Radiat Oncol Biol Phys 2008 ; 71 : 428-34
18. Bzdusek K, F riberger H, E riksson K, H ardemark B , Robinson D , Kaus M . Development and evaluation of an effi cient approach to volumetric arc therapy planning . Med Phys 2009 ; 36 : 2328-39
19. Deodato F , C illa S , M assaccesi M , M acchia G , I ppolito E , Caravatta L , et al . Daily on-line set-up correction in 3D-conformal radiotherapy: Is it feasible? Tumori 2012 ; 98 : 441-4
20. Morganti AG , D eodato F , Z izzari S , C illa S , D igesu ' C, Macchia G , et al . Complexity index (COMIX) and not type of treatment predicts undetected errors in radiotherapy planning and delivery . Radiother Oncol 2008 ; 89 : 320-9
21. Cilla S , V iola P , A zario L, G rimaldi L, C raus M , D 'O nofrio G , et al . Comparison of measured and computed portal dose for IMRT treatments J Appl Clin Med Phys 2006 ; 7 : 64-79
22. Van Esch A , C lermont C, D evillers M , I ori M , H uyskens DP . On-line quality assurance of rotational radiotherapy treatment delivery by means of a 2D ion chamber array and the Octavius phantom . Med Phys 2007 ; 34 : 3825-37
23. Baglan KL, F razier RC , Y an D , H uang RR , M artinez AA , Robertson JM . The dose-volume relationship of acute small bowel toxicity from concurrent 5-FU-based chemotherapy and radiation therapy for rectal cancer . Int J Radiat Oncol Biol Phys 2002 ; 52 : 176-83
24. Wong E, D 'S ouza DP , C hen JZ, L ock M , R odrigues G , C oad T , et al . Intensity-modulated arc therapy for treatment of high-risk endometrial malignancies . Int J Radiat Oncol Biol Phys 2005 ; 61 : 830-41
25. Vandecasteele K , T ummers P , M akar A , v an Eijkeren M , Delrue L , Denys H , et al . Postoperative intensity-modulated arc therapy for cervical and endometrial cancer: A prospective report on toxicity . Int J Radiat Oncol Biol Phys 2012 ; 84 : 408-14 .