-
1
-
-
0035811625
-
Hepatitis C Virus Infection
-
Lauer GM, Walker BD. Hepatitis C Virus Infection. N Engl J Med. 2001;345:41-52.
-
(2001)
N Engl J Med
, vol.345
, pp. 41-52
-
-
Lauer, G.M.1
Walker, B.D.2
-
2
-
-
79953173221
-
Boceprevir for untreated chronic HCV genotype 1 infection
-
Poordad F, McCone J Jr, Bacon BR, et al. Boceprevir for untreated chronic HCV genotype 1 infection. N Engl J Med. 2011;364(13):1195-1206.
-
(2011)
N Engl J Med
, vol.364
, Issue.13
, pp. 1195-1206
-
-
Poordad, F.1
McCone Jr., J.2
Bacon, B.R.3
-
3
-
-
79959438789
-
Telaprevir for previously untreated chronic hepatitis C virus infection
-
Jacobson IM, McHutchison JG, Dusheiko G, et al. Telaprevir for previously untreated chronic hepatitis C virus infection. N Engl J Med. 2011;364(25):2405-2416.
-
(2011)
N Engl J Med
, vol.364
, Issue.25
, pp. 2405-2416
-
-
Jacobson, I.M.1
McHutchison, J.G.2
Dusheiko, G.3
-
4
-
-
80052826527
-
Response-guided telaprevir combination treatment for hepatitis C virus infection
-
Sherman KE, Flamm SL, Afdhal NH, et al. Response-guided telaprevir combination treatment for hepatitis C virus infection. N Engl J Med. 2011;365(11):1014-1024.
-
(2011)
N Engl J Med
, vol.365
, Issue.11
, pp. 1014-1024
-
-
Sherman, K.E.1
Flamm, S.L.2
Afdhal, N.H.3
-
5
-
-
79953176289
-
Boceprevir for previously treated chronic HCV genotype 1 infection
-
Bacon BR, Gordon SC, Lawitz E, et al. Boceprevir for previously treated chronic HCV genotype 1 infection. N Engl J Med. 2011;364(13): 1207-1217.
-
(2011)
N Engl J Med
, vol.364
, Issue.13
, pp. 1207-1217
-
-
Bacon, B.R.1
Gordon, S.C.2
Lawitz, E.3
-
6
-
-
79959381354
-
Telaprevir for retreatment of HCV infection
-
Zeuzem S, Andreone P, Pol S, et al. Telaprevir for retreatment of HCV infection. N Engl J Med. 2011;364(25):2417-2428.
-
(2011)
N Engl J Med
, vol.364
, Issue.25
, pp. 2417-2428
-
-
Zeuzem, S.1
Andreone, P.2
Pol, S.3
-
7
-
-
84863649118
-
Hepatitis C therapy in non-genotype 1 patients: The near future
-
Wartelle-Bladou C, Le Folgoc G, Bourliere M, Lecomte L. Hepatitis C therapy in non-genotype 1 patients: the near future. J Viral Hepat. 2012;19(8):525-536.
-
(2012)
J Viral Hepat
, vol.19
, Issue.8
, pp. 525-536
-
-
Wartelle-Bladou, C.1
Le Folgoc, G.2
Bourliere, M.3
Lecomte, L.4
-
8
-
-
84855924980
-
Dermatological side effects of hepatitis C and its treatment: Patient management in the era of direct-acting antivirals
-
Cacoub P, Bourliere M, Lubbe J, et al. Dermatological side effects of hepatitis C and its treatment: patient management in the era of direct-acting antivirals. J Hepatol. 2012;56(2):455-463.
-
(2012)
J Hepatol
, vol.56
, Issue.2
, pp. 455-463
-
-
Cacoub, P.1
Bourliere, M.2
Lubbe, J.3
-
9
-
-
84863529543
-
Ribavirin dose modifcation in treatment-naive and previously treated patients who received telaprevir combination treatment: No impact on sustained virologic response in phase 3 studies [abstract]
-
Sulkowski MS, Roberts S, Afdhal NH, et al. Ribavirin dose modifcation in treatment-naive and previously treated patients who received telaprevir combination treatment: no impact on sustained virologic response in phase 3 studies [abstract]. J Hepatol. 2012;56(Suppl 2): S459-S460.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Sulkowski, M.S.1
Roberts, S.2
Afdhal, N.H.3
-
10
-
-
84891727750
-
Timing and magnitude of ribavirin dose reduction do not impact sustained virologic response rates with boceprevir + peginterferon alfa-2b/ribavirin in the anemia management study in chronic HCV genotype 1 patients [abstract]
-
Poordad F, Lawitz E, Reddy KR, et al. Timing and magnitude of ribavirin dose reduction do not impact sustained virologic response rates with boceprevir + peginterferon alfa-2b/ribavirin in the anemia management study in chronic HCV genotype 1 patients [abstract]. Hepatology. 2012;56(Suppl S1):269A-270A.
-
(2012)
Hepatology
, vol.56
, Issue.SUPPL. S1
-
-
Poordad, F.1
Lawitz, E.2
Reddy, K.R.3
-
11
-
-
84877923863
-
Boceprevir combined with peginterferon alfa-2b/ribavirin in treatment-naive chronic HCV genotype 1 patients with compensated cirrhosis: Sustained virologic response and safety subanalyses from the anemia management study [abstract]
-
Lawitz E, Zeuzem S, Nyberg LM, Nelson DR, Rossaro L, Balart LA, et al. Boceprevir combined with peginterferon alfa-2b/ribavirin in treatment-naive chronic HCV genotype 1 patients with compensated cirrhosis: sustained virologic response and safety subanalyses from the anemia management study [abstract]. Hepatology. 2012; 56(Suppl):216A.
-
(2012)
Hepatology
, vol.56
, Issue.SUPPL.
-
-
Lawitz, E.1
Zeuzem, S.2
Nyberg, L.M.3
Nelson, D.R.4
Rossaro, L.5
Balart, L.A.6
-
12
-
-
80051920720
-
Second-wave protease inhibitors: Choosing an heir
-
Ciesek S, von Hahn T, Manns MP. Second-wave protease inhibitors: choosing an heir. Clin Liver Dis. 2011;15(3):597-609.
-
(2011)
Clin Liver Dis
, vol.15
, Issue.3
, pp. 597-609
-
-
Ciesek, S.1
von Hahn, T.2
Manns, M.P.3
-
13
-
-
79956073556
-
New protease inhibitors for HCV - help is on the way
-
Fusco DN, Chung RT. New protease inhibitors for HCV - help is on the way. J Hepatol. 2011;54(6):1087-1089.
-
(2011)
J Hepatol
, vol.54
, Issue.6
, pp. 1087-1089
-
-
Fusco, D.N.1
Chung, R.T.2
-
14
-
-
78650928878
-
New direct-acting antivirals' combination for the treatment of chronic hepatitis C
-
Asselah T, Marcellin P. New direct-acting antivirals' combination for the treatment of chronic hepatitis C. Liver Int. 2011;31(Suppl 1):68-77.
-
(2011)
Liver Int
, vol.31
, Issue.SUPPL. 1
, pp. 68-77
-
-
Asselah, T.1
Marcellin, P.2
-
15
-
-
84856906043
-
TMC 435 in combination with peginterferon and ribavirin in treatment naive HCV genotype 1 patients: Final results of the PILLAR phase IIB study [abstract]
-
Fried M, Buti M, Dore GJ, Flisiak R, Ferenci P, Jacobson IM, et al. TMC 435 in combination with peginterferon and ribavirin in treatment naive HCV genotype 1 patients: Final results of the PILLAR phase IIB study [abstract]. Hepatology. 2011;54(Suppl S1):1429A.
-
(2011)
Hepatology
, vol.54
, Issue.SUPPL. S1
-
-
Fried, M.1
Buti, M.2
Dore, G.J.3
Flisiak, R.4
Ferenci, P.5
Jacobson, I.M.6
-
16
-
-
84870398673
-
TMC435 in HCV genotype 1 patients who have failed previous pegylated interferon ribavirin treatment: Final SVR24 results of the ASPIRE trial [abstract]
-
Zeuzem S, Berg T, Gane E, et al. TMC435 in HCV genotype 1 patients who have failed previous pegylated interferon ribavirin treatment: Final SVR24 results of the ASPIRE trial [abstract]. J Hepatol. 2012;56(Suppl 2): S1-S2.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Zeuzem, S.1
Berg, T.2
Gane, E.3
-
17
-
-
79960470493
-
Silen-C1: Sustained virologic response and safety of BI201335 combined with peginterferon alfa-2a and ribavirin in treatment naive patients with chronic genotype 1 infection [abstract]
-
Sulkowski M, Ceasu E, Asselah T, et al. Silen-C1: sustained virologic response and safety of BI201335 combined with peginterferon alfa-2a and ribavirin in treatment naive patients with chronic genotype 1 infection [abstract]. J Hepatol. 2011;54(Suppl 1):S27.
-
(2011)
J Hepatol
, vol.54
, Issue.SUPPL. 1
-
-
Sulkowski, M.1
Ceasu, E.2
Asselah, T.3
-
18
-
-
79960453309
-
SILEN-C2: Sustained virologic response and safety of BI 201335 combined with peginterferon alfa-2A and ribavirin in chronic HCV genotype 1 patients with non-response to P/R [abstract]
-
Sulkowski M, Bourliere M, Bronowicki J P, et al. SILEN-C2: Sustained virologic response and safety of BI 201335 combined with peginterferon alfa-2A and ribavirin in chronic HCV genotype 1 patients with non-response to P/R [abstract]. J Hepatol. 2011;54(Suppl 1):S30.
-
(2011)
J Hepatol
, vol.54
, Issue.SUPPL. 1
-
-
Sulkowski, M.1
Bourliere, M.2
Bronowicki, J.P.3
-
19
-
-
84863696020
-
Rapid and sustained achievement of undetectable HCV RNA during treatment with ritonavir-boosted danoprevir/PEGIFN alfa-2A/RBV in HCV genotype 1 or 4 patients: DAUPHINE week 12 interim analysis [abstract]
-
Everson G, Cooper C, Hezode C, et al. Rapid and sustained achievement of undetectable HCV RNA during treatment with ritonavir-boosted danoprevir/PEGIFN alfa-2A/RBV in HCV genotype 1 or 4 patients: DAUPHINE week 12 interim analysis [abstract]. J Hepatol. 2012;56(Suppl 2):S466.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Everson, G.1
Cooper, C.2
Hezode, C.3
-
20
-
-
84878136958
-
Up to 100% SVR4 rates with ritonavir-boosted danoprevir, mericit-abine and ribavirin with or without peginterferon alfa-2a in HCV genotype 1-infected partial and null responders: Results from the MATTERHORN study [abstract]
-
Feld JJ, Jacobson I, Jensen DM, Foster GR, Pol S, Tam E, et al. Up to 100% SVR4 rates with ritonavir-boosted danoprevir, mericit-abine and ribavirin with or without peginterferon alfa-2a in HCV genotype 1-infected partial and null responders: results from the MATTERHORN study [abstract]. Hepatology. 2012;56(Suppl): 231A-232A.
-
(2012)
Hepatology
, vol.56
, Issue.SUPPL.
-
-
Feld, J.J.1
Jacobson, I.2
Jensen, D.M.3
Foster, G.R.4
Pol, S.5
Tam, E.6
-
21
-
-
84865563661
-
Vaniprevir with pegylated interferon alpha-2a and ribavirin in treatment-naive patients with chronic hepatitis C: A randomized phase II study
-
Manns M P, Gane E, Rodriguez-Torres M, et al. Vaniprevir with pegylated interferon alpha-2a and ribavirin in treatment-naive patients with chronic hepatitis C: a randomized phase II study. Hepatology. 2012;56(3):884-893.
-
(2012)
Hepatology
, vol.56
, Issue.3
, pp. 884-893
-
-
Manns, M.P.1
Gane, E.2
Rodriguez-Torres, M.3
-
22
-
-
84867265860
-
A phase 2B study of MK 7009 (vaniprevir) in patients with genotype 1 HCV infection who have failed previous pegylated interferon and ribavirin treatment [abstract]
-
Lawitz E, Rodriguez-Torres M, Stoehr A, Gane EJ, Serfaty L, Bhanja S, et al. A phase 2B study of MK 7009 (vaniprevir) in patients with genotype 1 HCV infection who have failed previous pegylated interferon and ribavirin treatment [abstract]. Hepatology. 2011;54: 1434A-1435A.
-
(2011)
Hepatology
, vol.54
-
-
Lawitz, E.1
Rodriguez-Torres, M.2
Stoehr, A.3
Gane, E.J.4
Serfaty, L.5
Bhanja, S.6
-
23
-
-
84870435875
-
ABT-450/ritonavir combined with pegylated interferon alpha-2A and ribavirin after 3 days mono-therapy in genotype 1 HCV-infected treatment-naive subjects: 12 weeks sustained virologic response and safety results [abstract]
-
Lawitz E, Poordad F, DeJesus E, et al. ABT-450/ritonavir combined with pegylated interferon alpha-2A and ribavirin after 3 days mono-therapy in genotype 1 HCV-infected treatment-naive subjects: 12 weeks sustained virologic response and safety results [abstract]. J Hepatol. 2012;56(Suppl 2):S470.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Lawitz, E.1
Poordad, F.2
Dejesus, E.3
-
24
-
-
84892150117
-
Continued high virologic response rates with ACH-1625 daily dosing plus pegIFN-alpha-2A in a 28 days and 12 week phase 2a trial [abstract]
-
Poordad F, Lalezari J, Lawitz E, Van Vlierberghe H, Shiffman ML, et al. Continued high virologic response rates with ACH-1625 daily dosing plus pegIFN-alpha-2A in a 28 days and 12 week phase 2a trial [abstract]. J Hepatol. 2012;56(Suppl 2):S455.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Poordad, F.1
Lalezari, J.2
Lawitz, E.3
van Vlierberghe, H.4
Shiffman, M.L.5
-
25
-
-
84866324555
-
Asunaprevir, an NS3 protease inhibitor in combination with peginterferon and ribavirin in treatment-naive patients with genotype 1 chronic hepatitis C infection [abstract]
-
Bronowicki J-P, Pol S, Thuluvath P, et al. Asunaprevir, an NS3 protease inhibitor in combination with peginterferon and ribavirin in treatment-naive patients with genotype 1 chronic hepatitis C infection [abstract]. J Hepatol. 2012;56(Suppl 2):S431-S432.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Bronowicki, J.-P.1
Pol, S.2
Thuluvath, P.3
-
26
-
-
84856159009
-
Preliminary study of two antiviral agents for hepatitis C genotype 1
-
Lok AS, Gardiner D F, Lawitz E, et al. Preliminary study of two antiviral agents for hepatitis C genotype 1. N Engl J Med. 2012;366(3): 216-224.
-
(2012)
N Engl J Med
, vol.366
, Issue.3
, pp. 216-224
-
-
Lok, A.S.1
Gardiner, D.F.2
Lawitz, E.3
-
27
-
-
84856457988
-
A phase IIA, open label study to assess the antiviral activity of TMC435 monotherapy in patients infected with HCV genotypes 2-6
-
Moreno C, Berg T, Tanwandee T, et al. A phase IIA, open label study to assess the antiviral activity of TMC435 monotherapy in patients infected with HCV genotypes 2-6. Hepatology. 2010;52(Suppl):749A-750A.
-
(2010)
Hepatology
, vol.52
, Issue.SUPPL.
-
-
Moreno, C.1
Berg, T.2
Tanwandee, T.3
-
28
-
-
84879602635
-
Ritonavir-boosted danoprevir plus peginterferon alfa-2a/ribavirin demonstrates up to 100% SVR24 with 12 or 24 weeks of total treatment in treatment-naive patients with genotype 4 infection in the DAUPHINE study [abstract]
-
Hezode C, Shiffman ML, Cooper C, et al. Ritonavir-boosted danoprevir plus peginterferon alfa-2a/ribavirin demonstrates up to 100% SVR24 with 12 or 24 weeks of total treatment in treatment-naive patients with genotype 4 infection in the DAUPHINE study [abstract]. Hepatology. 2012;56(Suppl):557A.
-
(2012)
Hepatology
, vol.56
, Issue.SUPPL.
-
-
Hezode, C.1
Shiffman, M.L.2
Cooper, C.3
-
29
-
-
78751608735
-
Safety and antiviral activity of MK-5172 a novel HCV NS3/4A protease inhibitors with potent activity against known resistance mutants in genotype 1 and 3 HCV-infected patients [abstract]
-
Brainard DM, Petry A, Van Dyck K, et al. Safety and antiviral activity of MK-5172 a novel HCV NS3/4A protease inhibitors with potent activity against known resistance mutants in genotype 1 and 3 HCV-infected patients [abstract]. Hepatolog y. 2010;52(Suppl):706A-707A.
-
(2010)
Hepatolog Y
, vol.52
, Issue.SUPPL.
-
-
Brainard, D.M.1
Petry, A.2
van Dyck, K.3
-
31
-
-
80052070428
-
The HCV NS5B nucleoside and non-nucleoside inhibitors
-
Membreno FE, Lawitz EJ. The HCV NS5B nucleoside and non-nucleoside inhibitors. Clin Liver Dis. 2011;15(3):611-626.
-
(2011)
Clin Liver Dis
, vol.15
, Issue.3
, pp. 611-626
-
-
Membreno, F.E.1
Lawitz, E.J.2
-
32
-
-
84863680448
-
Effcacy and safety of mericitabine in combination with PEG-IFN alfa-2A/RBV in G1/4 treatment naive HCV patients: Final analysis from the PROPEL study [abstract]
-
Wedemeyer H, Jensen D, Herring R Jr, et al. Effcacy and safety of mericitabine in combination with PEG-IFN alfa-2A/RBV in G1/4 treatment naive HCV patients: Final analysis from the PROPEL study [abstract]. J Hepatol. 2012;56(Suppl 2):S481-S482.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Wedemeyer, H.1
Jensen, D.2
Herring Jr., R.3
-
33
-
-
84863650706
-
SVR-12 among G1/4 treatment-naive patients receiving mericitabine in combination with PEG-IFN alfa-2A/ RBV: Interim analysis from the JUMP-C study [abstract]
-
Pockros P, Jensen D, Tsai N, et al. SVR-12 among G1/4 treatment-naive patients receiving mericitabine in combination with PEG-IFN alfa-2A/ RBV: interim analysis from the JUMP-C study [abstract]. J Hepatol. 2012;56(Suppl 2):S477-S478.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Pockros, P.1
Jensen, D.2
Tsai, N.3
-
34
-
-
77958162291
-
Sustained virologic response following RG7128 1500 mg BID/PEG-IFN/RBV for 28 days in HCV genotype 2/3 prior non responders [abstract]
-
Gane EJ, Rodriguez-Torres M, Nelson DE, et al. Sustained virologic response following RG7128 1500 mg BID/PEG-IFN/RBV for 28 days in HCV genotype 2/3 prior non responders [abstract]. J Hepatol. 2010;52(Suppl 1):S16.
-
(2010)
J Hepatol
, vol.52
, Issue.SUPPL. 1
-
-
Gane, E.J.1
Rodriguez-Torres, M.2
Nelson, D.E.3
-
35
-
-
84871814966
-
Nucleotide polymerase inhibitor sofosbuvir plus ribavirin for hepatitis C
-
Gane EJ, Stedman CA, Hyland RH, et al. Nucleotide polymerase inhibitor sofosbuvir plus ribavirin for hepatitis C. N Engl J Med. 2013;368(1): 34-44.
-
(2013)
N Engl J Med
, vol.368
, Issue.1
, pp. 34-44
-
-
Gane, E.J.1
Stedman, C.A.2
Hyland, R.H.3
-
36
-
-
84872045978
-
Once daily sofosbuvir (GS-7977) plus ribavirin in patients with HCV genotypes 1, 2 and 3: The ELECTRON trial
-
Gane EJ, Stedman CA, Hyland RH, et al. Once daily sofosbuvir (GS-7977) plus ribavirin in patients with HCV genotypes 1, 2 and 3: The ELECTRON trial. Hepatology. 2012;56(Suppl):306A.
-
(2012)
Hepatology
, vol.56
, Issue.SUPPL.
-
-
Gane, E.J.1
Stedman, C.A.2
Hyland, R.H.3
-
37
-
-
79960471533
-
Once daily PSI-7977 plus PEGIFN/RBV in a phase 2B trial: Rapid virologic suppression in treatment-naive patients with HCV GT2/GT3 [abstract]
-
Lalezari J, Lawitz E, Rodriguez-Torres M, et al. Once daily PSI-7977 plus PEGIFN/RBV in a phase 2B trial: Rapid virologic suppression in treatment-naive patients with HCV GT2/GT3 [abstract]. J Hepatol. 2011;54(Suppl 1):S28.
-
(2011)
J Hepatol
, vol.54
, Issue.SUPPL. 1
-
-
Lalezari, J.1
Lawitz, E.2
Rodriguez-Torres, M.3
-
38
-
-
84869837557
-
PSI-7977 PROTON and ELECTRON: 100% concordance of SV4 with SVR24 in HCV GT1, GT2 and GT3 [abstract]
-
Lawitz E, Gane E, Stedman C, et al. PSI-7977 PROTON and ELECTRON: 100% concordance of SV4 with SVR24 in HCV GT1, GT2 and GT3 [abstract]. J Hepatol. 2012;56(Suppl 2):S4.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Lawitz, E.1
Gane, E.2
Stedman, C.3
-
39
-
-
84872011904
-
Once daily sofosbuvir (GS-7977) plus PEG/RBV: High early response rates are maintained during post-treatment follow-up in treatment naive patients with HCV genotype 1, 4 and 6 infection in the ATOMIC study [abstract]
-
Hassanein T, Lawitz E, Crespo I, et al. Once daily sofosbuvir (GS-7977) plus PEG/RBV: high early response rates are maintained during post-treatment follow-up in treatment naive patients with HCV genotype 1, 4 and 6 infection in the ATOMIC study [abstract]. Hepatology. 2012;56(Suppl):307A.
-
(2012)
Hepatology
, vol.56
, Issue.SUPPL.
-
-
Hassanein, T.1
Lawitz, E.2
Crespo, I.3
-
40
-
-
84862696759
-
Rapid and strong antiviral activity of the non-nucleosidic NS5B polymerase inhibitor BI 207127 in combination with peginterferon alfa 2a and ribavirin
-
Larrey D, Lohse AW, de Ledinghen V, et al. Rapid and strong antiviral activity of the non-nucleosidic NS5B polymerase inhibitor BI 207127 in combination with peginterferon alfa 2a and ribavirin. J Hepatol. 2012;57(1):39-46.
-
(2012)
J Hepatol
, vol.57
, Issue.1
, pp. 39-46
-
-
Larrey, D.1
Lohse, A.W.2
de Ledinghen, V.3
-
41
-
-
78751620008
-
Virologic response rates following 4 weeks of flibuvir in combination with pegylated interferon alfa-2A and ribavirin in chronically-infected HCV genotype-1 patients [abstract]
-
Jacobson I, Pockros PJ, Lalezari J, et al. Virologic response rates following 4 weeks of flibuvir in combination with pegylated interferon alfa-2A and ribavirin in chronically-infected HCV genotype-1 patients [abstract]. J Hepatol. 2010;52(Suppl 1):S465.
-
(2010)
J Hepatol
, vol.52
, Issue.SUPPL. 1
-
-
Jacobson, I.1
Pockros, P.J.2
Lalezari, J.3
-
42
-
-
77954745283
-
Safety and antiviral activity of the HCV non-nucleoside polymerase inhibitor VX-222 in treatment-naive genotype 1 HCV infected patients [abstract]
-
Rodriguez-Torres M, Lawitz E, Conway B, et al. Safety and antiviral activity of the HCV non-nucleoside polymerase inhibitor VX-222 in treatment-naive genotype 1 HCV infected patients [abstract]. J Hepatol. 2010;52(Suppl 1):S14.
-
(2010)
J Hepatol
, vol.52
, Issue.SUPPL. 1
-
-
Rodriguez-Torres, M.1
Lawitz, E.2
Conway, B.3
-
43
-
-
78751637124
-
Safety and antiviral activity of ANA 598 in combination with pegylated interferon alfa-2A plus ribavirin in treatment-naive genotype 1 chronic HCV patients [abstract]
-
Lawitz E, Rodriguez-Torres M, Rustgi VK, et al. Safety and antiviral activity of ANA 598 in combination with pegylated interferon alfa-2A plus ribavirin in treatment-naive genotype 1 chronic HCV patients [abstract]. Hepatolog y. 2010;52(Suppl):334A-335A.
-
(2010)
Hepatolog Y
, vol.52
, Issue.SUPPL.
-
-
Lawitz, E.1
Rodriguez-Torres, M.2
Rustgi, V.K.3
-
44
-
-
84870431451
-
ABT-072 or ABT-333 combined with pegylated interferon and ribavirin after 3 days monotherapy in HCV genotype 1 infected treatment-naive subjects: 12 week sustained virologic response and safety results [abstract]
-
Poordad F, Lawitz E, DeJesus E, et al. ABT-072 or ABT-333 combined with pegylated interferon and ribavirin after 3 days monotherapy in HCV genotype 1 infected treatment-naive subjects: 12 week sustained virologic response and safety results [abstract]. J Hepatol. 2012; 56(Suppl 2):S478.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Poordad, F.1
Lawitz, E.2
Dejesus, E.3
-
45
-
-
79960747322
-
A phase 2B trial comparing 24 to 48 weeks treatment with tegobuvir (GS-9190)/PEG/RBV to 48 weeks treatment with PEG/RBV for chronic genotype 1 HCV infection [abstract]
-
Lawitz E, Jacobson I, Godofsky E, et al. A phase 2B trial comparing 24 to 48 weeks treatment with tegobuvir (GS-9190)/PEG/RBV to 48 weeks treatment with PEG/RBV for chronic genotype 1 HCV infection [abstract]. J Hepatol. 2011;54(Suppl 1):S181.
-
(2011)
J Hepatol
, vol.54
, Issue.SUPPL. 1
-
-
Lawitz, E.1
Jacobson, I.2
Godofsky, E.3
-
46
-
-
84870024853
-
HCV NS5A inhibitors in development
-
Suk-Fong Lok A. HCV NS5A inhibitors in development. Clin Liver Dis. 2013;17:111-121.
-
(2013)
Clin Liver Dis
, vol.17
, pp. 111-121
-
-
Suk-Fong Lok, A.1
-
47
-
-
84878119417
-
Daclatasvir an NS5A replication complex inhibitor, combined with peginterferon alfa-2a and ribavirin in treatment naive HCV genotype 1or 4 subjects: Phase 2b COMMAND-1 SVR12 results [abstract]
-
Hezode C, Hirschfield GM, Ghesquiere W, et al. Daclatasvir an NS5A replication complex inhibitor, combined with peginterferon alfa-2a and ribavirin in treatment naive HCV genotype 1or 4 subjects: phase 2b COMMAND-1 SVR12 results [abstract]. Hepatology. 2012; 56(Suppl):553A.
-
(2012)
Hepatology
, vol.56
, Issue.SUPPL.
-
-
Hezode, C.1
Hirschfield, G.M.2
Ghesquiere, W.3
-
48
-
-
84865282780
-
Triple therapy with daclatasvir, peginterferon alfa-2a and ribavirin in HCV infected prior null and partial responders: 12 weeks results of phase 2b COMMAND-2 trial [abstract]
-
Ratziu V, Gadano A, Pol S, et al. Triple therapy with daclatasvir, peginterferon alfa-2a and ribavirin in HCV infected prior null and partial responders: 12 weeks results of phase 2b COMMAND-2 trial [abstract]. J Hepatol. 2012;56(Suppl 2):S478-S479.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Ratziu, V.1
Gadano, A.2
Pol, S.3
-
49
-
-
84892162602
-
Twelve or 16 week treatment with daclatasvir combined with peginterferon alfa and ribavirin for hepatitis C virus genotype 2 or 3 infection: COMMAND GT2/3 study [abstract]
-
Dore GJ, Lawitz E, Hezode C, et al. Twelve or 16 week treatment with daclatasvir combined with peginterferon alfa and ribavirin for hepatitis C virus genotype 2 or 3 infection: COMMAND GT2/3 study [abstract]. Hepatology. 2012;56(Suppl):558A-559A.
-
(2012)
Hepatology
, vol.56
, Issue.SUPPL.
-
-
Dore, G.J.1
Lawitz, E.2
Hezode, C.3
-
50
-
-
84872033846
-
Sustained virologic response in chronic HCV genotype 1-infected null responders with the combination of daclatasvir and asunaprevir with or without peginter-feron alfa-2a/ribavirin [abstract]
-
Lok AS, Gardiner D F, Hezode C, et al. Sustained virologic response in chronic HCV genotype 1-infected null responders with the combination of daclatasvir and asunaprevir with or without peginter-feron alfa-2a/ribavirin [abstract]. Hepatology. 2012;56(Suppl): 230A.
-
(2012)
Hepatology
, vol.56
, Issue.SUPPL.
-
-
Lok, A.S.1
Gardiner, D.F.2
Hezode, C.3
-
51
-
-
84872022905
-
High rate of sustained virologic response with all-oral combination of daclatasvir (NS5A inhibitor) plus sofosbuvir (Nucleotide NS5B inhibitor) with or without ribavirin, in treatment-naive patients chronically infected with HCV genotype 1,2 or 3 [abstract
-
LB-2
-
Sulkowski MS, Gardiner DF, Rodriguez-Torres M, et al. High rate of sustained virologic response with all-oral combination of daclatasvir (NS5A inhibitor) plus sofosbuvir (Nucleotide NS5B inhibitor) with or without ribavirin, in treatment-naive patients chronically infected with HCV genotype 1,2 or 3 [abstract]. Hepatology. 2012; 56(Suppl):LB-2.
-
(2012)
Hepatology
, vol.56
, Issue.SUPPL.
-
-
Sulkowski, M.S.1
Gardiner, D.F.2
Rodriguez-Torres, M.3
-
52
-
-
84866784148
-
ABT-267 combined with pegylated interferon alpha-2A and ribavirin in genotype 1 HCV-infected treatment-naive subject: 12 week antiviral and safety analysis [abstract]
-
Sullivan GJ, Rodriguez-Torres M, Lawitz E, et al. ABT-267 combined with pegylated interferon alpha-2A and ribavirin in genotype 1 HCV-infected treatment-naive subject: 12 week antiviral and safety analysis [abstract]. J Hepatol. 2012;56(Suppl 2):S480.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Sullivan, G.J.1
Rodriguez-Torres, M.2
Lawitz, E.3
-
53
-
-
84863678711
-
High sustained virologic response rate in treatment-naive HCV genotype 1A and 1B patients treated for 12 weeks with an interferon-free all-oral quad regimen: Interim results [abstract]
-
Sulkowski MS, Rodriguez-Torres M, Lawitz E, et al. High sustained virologic response rate in treatment-naive HCV genotype 1A and 1B patients treated for 12 weeks with an interferon-free all-oral quad regimen: interim results [abstract]. J Hepatol. 2012;56(Suppl 2):S560.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Sulkowski, M.S.1
Rodriguez-Torres, M.2
Lawitz, E.3
-
54
-
-
40949117600
-
The cyclophilin inhibitor Debio-025 shows potent anti-hepatitis C effect in patients coinfected with hepatitis C and human immunodefciency virus
-
Flisiak R, Horban A, Gallay P, et al. The cyclophilin inhibitor Debio-025 shows potent anti-hepatitis C effect in patients coinfected with hepatitis C and human immunodefciency virus. Hepatology. 2008;47(3): 817-826.
-
(2008)
Hepatology
, vol.47
, Issue.3
, pp. 817-826
-
-
Flisiak, R.1
Horban, A.2
Gallay, P.3
-
56
-
-
84870030071
-
Alisporivir plus peginterferon/ ribavirin in HCV genotype 1 treatment-experienced patients achieves primary endpoint with superior effcacy at treatment week 12 compared to retreatment with PR [abstract]
-
Alberti A, Chuang WL, Flisiak R, et al. Alisporivir plus peginterferon/ ribavirin in HCV genotype 1 treatment-experienced patients achieves primary endpoint with superior effcacy at treatment week 12 compared to retreatment with PR [abstract]. J Hepatol. 2012;56(Suppl 2): S553-S554.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Alberti, A.1
Chuang, W.L.2
Flisiak, R.3
-
57
-
-
84863704212
-
Alisporivir plus ribavirin is highly effective as interferon-free or interferon-add-on regimen in previously untreated HCV-GT2or GT3 patients: SVR12 results from VITAL-1 phase 2b study [abstract]
-
Pawlostky J-M, Sarin SK, Foster G, et al. Alisporivir plus ribavirin is highly effective as interferon-free or interferon-add-on regimen in previously untreated HCV-GT2or GT3 patients: SVR12 results from VITAL-1 phase 2b study [abstract]. J Hepatol. 2012;56(Suppl 2):S553.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Pawlostky, J.-M.1
Sarin, S.K.2
Foster, G.3
-
58
-
-
84890123431
-
Significant improvement of complete EVR in HCVAC phase II clinical trial when adding TG4040 therapeutic vaccine to PEGIFN alfa-2A and ribavirin [abstract]
-
Wedemeyer H, Janczewska E, Wlodzimierz M, et al. Significant improvement of complete EVR in HCVAC phase II clinical trial when adding TG4040 therapeutic vaccine to PEGIFN alfa-2A and ribavirin [abstract]. J Hepatol. 2012;56(Suppl 2):S552.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Wedemeyer, H.1
Janczewska, E.2
Wlodzimierz, M.3
-
59
-
-
84863720486
-
High-dose silibinin rescue treatment for HCV-infected patients showing suboptimal virologic response to standard combination therapy
-
Biermer M, Schlosser B, Fulop B, et al. High-dose silibinin rescue treatment for HCV-infected patients showing suboptimal virologic response to standard combination therapy. J Viral Hepat. 2012;19(8): 547-553.
-
(2012)
J Viral Hepat
, vol.19
, Issue.8
, pp. 547-553
-
-
Biermer, M.1
Schlosser, B.2
Fulop, B.3
-
60
-
-
84880283111
-
Peginterferon Lambda-1a compared to peginterferon alpha-2a in treatment-naive patients with HCV genotype 1 or 4. SVR24 from EMERGE phase 2b [abstract]
-
Muir AJ, Hillson JA, Gray TE, et al. Peginterferon Lambda-1a compared to peginterferon alpha-2a in treatment-naive patients with HCV genotype 1 or 4. SVR24 from EMERGE phase 2b [abstract]. Hepatol-ogy. 2012;56(Suppl):299A.
-
(2012)
Hepatol-ogy
, vol.56
, Issue.SUPPL.
-
-
Muir, A.J.1
Hillson, J.A.2
Gray, T.E.3
-
61
-
-
78049527728
-
Oral combination therapy with a nucleoside polymerase inhibitor (RG7128) and danoprevir for chronic hepatitis C genotype 1 infection (INFORM-1): A randomised, double-blind, placebo-controlled, dose-escalation trial
-
Gane EJ, Roberts SK, Stedman CA, et al. Oral combination therapy with a nucleoside polymerase inhibitor (RG7128) and danoprevir for chronic hepatitis C genotype 1 infection (INFORM-1): a randomised, double-blind, placebo-controlled, dose-escalation trial. Lancet. 2010;376(9751):1467-1475.
-
(2010)
Lancet
, vol.376
, Issue.9751
, pp. 1467-1475
-
-
Gane, E.J.1
Roberts, S.K.2
Stedman, C.A.3
-
62
-
-
84866119318
-
Interferon-free treatment with a combination of mericitabine and danoprevir/R with or without riba-virin in treatment-naive HCV genotype 1 infected patients [abstract]
-
Gane EJ, Pockros P, Zeuzem S, et al. Interferon-free treatment with a combination of mericitabine and danoprevir/R with or without riba-virin in treatment-naive HCV genotype 1 infected patients [abstract]. J Hepatol. 2012;56(Suppl 2):S555-S556.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Gane, E.J.1
Pockros, P.2
Zeuzem, S.3
-
63
-
-
81855228070
-
Effcacy of the protease inhibitor BI 201335, polymerase inhibitor BI 207127, and ribavirin in patients with chronic HCV infection
-
Zeuzem S, Asselah T, Angus P, et al. Effcacy of the protease inhibitor BI 201335, polymerase inhibitor BI 207127, and ribavirin in patients with chronic HCV infection. Gastroenterology. 2011;141(6):2047-2055.
-
(2011)
Gastroenterology
, vol.141
, Issue.6
, pp. 2047-2055
-
-
Zeuzem, S.1
Asselah, T.2
Angus, P.3
-
64
-
-
84866244136
-
SVR4 and SVR12 with an interferon-free regimen of BI201335 and BI207127 +/- ribavirin in treatment naive patients with chronic genotype 1 HCV infection; interim results of SOUND-C2 [abstract]
-
Zeuzem S, Soriano V, Asselah T, et al. SVR4 and SVR12 with an interferon-free regimen of BI201335 and BI207127 +/- ribavirin in treatment naive patients with chronic genotype 1 HCV infection; interim results of SOUND-C2 [abstract]. J Hepatol. 2012; 56(Suppl 2):S45.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Zeuzem, S.1
Soriano, V.2
Asselah, T.3
-
65
-
-
84872026703
-
Interferon-free combination treatment with HCV NS3/NS4 protease inhibitor BI201335 and the non nucleoside NS5B inhibitor BI 207127 with or without ribavirin: Final results of SOUND-C2 and predictors of response [abstract]
-
Zeuzem S, Soriano V, Asselah T, et al. Interferon-free combination treatment with HCV NS3/NS4 protease inhibitor BI201335 and the non nucleoside NS5B inhibitor BI 207127 with or without ribavirin: Final results of SOUND-C2 and predictors of response [abstract]. Hepatology. 2012;56(Suppl):308A-309A.
-
(2012)
Hepatology
, vol.56
, Issue.SUPPL.
-
-
Zeuzem, S.1
Soriano, V.2
Asselah, T.3
-
66
-
-
80051915933
-
VX-222 with TVR alone or in combination with peginterferon alfa-2a and ribavirin in treatment naive patients with chronic hepatitis C: ZENITH study interim results [abstract]
-
Di Bisceglie AM, Nelson DR, Gane E, et al. VX-222 with TVR alone or in combination with peginterferon alfa-2a and ribavirin in treatment naive patients with chronic hepatitis C: ZENITH study interim results [abstract]. J Hepatol. 2011;54(Suppl 1):S540.
-
(2011)
J Hepatol
, vol.54
, Issue.SUPPL. 1
-
-
Di Bisceglie, A.M.1
Nelson, D.R.2
Gane, E.3
-
67
-
-
84872026579
-
VX-222, telaprevir and riba-virin in treatment-naive patients with genotype 1 chronic hepatitis C: Results of the ZENITH study interferon-free regimen [abstract]
-
Jacobson I, Sulkowski MS, Gane EJ, et al. VX-222, telaprevir and riba-virin in treatment-naive patients with genotype 1 chronic hepatitis C: results of the ZENITH study interferon-free regimen [abstract]. Hepa-tolog y. 2012;56(Suppl):308A.
-
(2012)
Hepa-tolog Y
, vol.56
, Issue.SUPPL.
-
-
Jacobson, I.1
Sulkowski, M.S.2
Gane, E.J.3
-
68
-
-
78650957102
-
Dual, triple and quadruple combination treatment with a protease inhibitor (GS-9256) and a polymerase inhibitor (GS-9190) alone and in combination with ribavirin (RBV) or PegIFN/RBV for up to 28 days in treatment naive genotype 1 HCV subjects [abstract]
-
Zeuzem S, Buggisch P, Agarwal K, et al. Dual, triple and quadruple combination treatment with a protease inhibitor (GS-9256) and a polymerase inhibitor (GS-9190) alone and in combination with ribavirin (RBV) or PegIFN/RBV for up to 28 days in treatment naive genotype 1 HCV subjects [abstract]. Hepatology. 2010;52(Suppl):400A.
-
(2010)
Hepatology
, vol.52
, Issue.SUPPL.
-
-
Zeuzem, S.1
Buggisch, P.2
Agarwal, K.3
-
69
-
-
84864379265
-
12 week interferon-free regimen of ABT-450/R + ABT-333 + ribavirin achieved SVR12 in more than 90% of treatment-naive HCV genotype 1 infected subjects and 47% of previous non-responders [abstract]
-
Poordad F, Lawitz E, Kowdley K V, et al. 12 week interferon-free regimen of ABT-450/R + ABT-333 + ribavirin achieved SVR12 in more than 90% of treatment-naive HCV genotype 1 infected subjects and 47% of previous non-responders [abstract]. J Hepatol. 2012;56(Suppl 2): S549-S550.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Poordad, F.1
Lawitz, E.2
Kowdley, K.V.3
-
70
-
-
84879602765
-
A 12 week interferon-free treatment regimen with ABT-450/R, ABT-267, ABT-333 and ribavirin achieves a SVR12 rates (observed data) of 99% in treatment-naive patients and 93% in prior null responders with HCV genotype 1 infection
-
LB-1
-
Kowdley K V, Lawitz E, Poordad F, et al. A 12 week interferon-free treatment regimen with ABT-450/R, ABT-267, ABT-333 and ribavirin achieves a SVR12 rates (observed data) of 99% in treatment-naive patients and 93% in prior null responders with HCV genotype 1 infection Hepatology. 2012;56(Suppl):LB-1.
-
(2012)
Hepatology
, vol.56
, Issue.SUPPL.
-
-
Kowdley, K.V.1
Lawitz, E.2
Poordad, F.3
-
71
-
-
84867566926
-
A 12 week interferon-free regimen of ABT-450/R, ABT-072 and ribavirin was well tolerated and achieved sustained virologic response in 91% treatment-naive HCV IL28B-CC genotype1 infected subjects [abstract]
-
Lawitz E, Poordad F, Kowdley K V, et al. A 12 week interferon-free regimen of ABT-450/R, ABT-072 and ribavirin was well tolerated and achieved sustained virologic response in 91% treatment-naive HCV IL28B-CC genotype1 infected subjects [abstract]. J Hepatol. 2012;56(Suppl 2):S7.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Lawitz, E.1
Poordad, F.2
Kowdley, K.V.3
-
72
-
-
84857395452
-
Dual therapy with the nonstruc-tural protein 5A inhibitor, daclatasvir, and the nonstructural protein 3 protease inhibitor, asunaprevir, in hepatitis C virus genotype 1b-infected null responders
-
Chayama K, Takahashi S, Toyota J, et al. Dual therapy with the nonstruc-tural protein 5A inhibitor, daclatasvir, and the nonstructural protein 3 protease inhibitor, asunaprevir, in hepatitis C virus genotype 1b-infected null responders. Hepatology. 2012;55(3):742-748.
-
(2012)
Hepatology
, vol.55
, Issue.3
, pp. 742-748
-
-
Chayama, K.1
Takahashi, S.2
Toyota, J.3
-
73
-
-
84863678711
-
Potent viral suppression with the all-oral combination of daclatasvir (NS5A inhibitor) and GS-7977 (nucleotide NS5B inhibitor +/- ribavirin in treatment-naive patients with chronic HCV GT1,2, or 3 [abstract]
-
Sulkowski M, Gardiner D, Lawitz E, et al. Potent viral suppression with the all-oral combination of daclatasvir (NS5A inhibitor) and GS-7977 (nucleotide NS5B inhibitor +/- ribavirin in treatment-naive patients with chronic HCV GT1,2, or 3 [abstract]. J Hepatol. 2012;56(Suppl 2):S560.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Sulkowski, M.1
Gardiner, D.2
Lawitz, E.3
-
74
-
-
84880288564
-
An interferon-free, ribavirin-free 12-week regimen of daclatasvir, asunaprevir and BMS-791325 yielded SVR4 of 94% in treatment-naive patients with genotype 1 chronic hepatitis C virus infection [abstract]
-
LB-3
-
Everson GT, Sims KD, Rodriguez-Torres M, et al. An interferon-free, ribavirin-free 12-week regimen of daclatasvir, asunaprevir and BMS-791325 yielded SVR4 of 94% in treatment-naive patients with genotype 1 chronic hepatitis C virus infection [abstract]. Hepatology. 2012;56(Suppl):LB-3.
-
(2012)
Hepatology
, vol.56
, Issue.SUPPL.
-
-
Everson, G.T.1
Sims, K.D.2
Rodriguez-Torres, M.3
-
75
-
-
84865418147
-
VX222/Telaprevir in combination with peginterferon alfa-2A and ribavirin in treatment-naive genotype 1 HCV patients treated for 12 weeks: ZENITH study, SVR12 interil analysis [abstract]
-
Nelson DR, Gane EJ, Jacobson IM, et al. VX222/Telaprevir in combination with peginterferon alfa-2A and ribavirin in treatment-naive genotype 1 HCV patients treated for 12 weeks: ZENITH study, SVR12 interil analysis [abstract]. Hepatolog y. 2011;54(Suppl):1435A.
-
(2011)
Hepatolog Y
, vol.54
, Issue.SUPPL.
-
-
Nelson, D.R.1
Gane, E.J.2
Jacobson, I.M.3
-
77
-
-
84863700658
-
Worldwide experience treating chronic hepatitis C with peginterferon alfa/ribavirin: Final results from 7163 naive mono-infected patients enrolled in the large multinational PROPHESYS cohort study
-
Marcellin P, Cheinquer H, Curescu M, et al. Worldwide experience treating chronic hepatitis C with peginterferon alfa/ribavirin: Final results from 7163 naive mono-infected patients enrolled in the large multinational PROPHESYS cohort study. Hepatology. 2011; 54(Suppl):824A.
-
(2011)
Hepatology
, vol.54
, Issue.SUPPL.
-
-
Marcellin, P.1
Cheinquer, H.2
Curescu, M.3
-
78
-
-
79960453276
-
EASL Clinical Practice Guidelines: Management of hepatitis C virus infection
-
European Association for the Study of the Liver
-
European Association for the Study of the Liver. EASL Clinical Practice Guidelines: management of hepatitis C virus infection. J Hepatol. 2011;55(2):245-264.
-
(2011)
J Hepatol
, vol.55
, Issue.2
, pp. 245-264
-
-
-
79
-
-
80052116134
-
Telaprevir alone or with peginter-feron and ribavirin reduces HCV RNA in patients with chronic genotype 2 but not genotype 3 infections
-
e1
-
Foster GR, Hezode C, Bronowicki J P, et al. Telaprevir alone or with peginter-feron and ribavirin reduces HCV RNA in patients with chronic genotype 2 but not genotype 3 infections. Gastroenterology. 2011;141(3):881-889. e1.
-
(2011)
Gastroenterology
, vol.141
, Issue.3
, pp. 881-889
-
-
Foster, G.R.1
Hezode, C.2
Bronowicki, J.P.3
-
80
-
-
78751631356
-
Activity of telaprevir or in combination with peginterferon alfa-2a and ribavirin in treatment naive genotype 4 hepatitis C patients. Final results of study C210. [abstract]
-
Benhamou Y, Moussalli J, Ratziu V, et al. Activity of telaprevir or in combination with peginterferon alfa-2a and ribavirin in treatment naive genotype 4 hepatitis C patients. Final results of study C210. [abstract]. Hepatology. 2010;52(Suppl):719A-720A.
-
(2010)
Hepatology
, vol.52
, Issue.SUPPL.
-
-
Benhamou, Y.1
Moussalli, J.2
Ratziu, V.3
-
81
-
-
84892180762
-
-
Silva MO, Kasserra C, Gupta A, Treitel M, Hughes E, O'Mara E. Antiviral activity of boceprevir monotherapy in treatment-naive subjects with chronic hepatitis C genotype 2/3 A PASL Feb 17-20, 2011. 2011;10:13-66.
-
(2011)
Antiviral Activity of Boceprevir Monotherapy In Treatment-naive Subjects With Chronic Hepatitis C Genotype 2/3 a PASL Feb 17-20, 2011
, vol.10
, pp. 13-66
-
-
Silva, M.O.1
Kasserra, C.2
Gupta, A.3
Treitel, M.4
Hughes, E.5
O'Mara, E.6
-
82
-
-
84864387126
-
MK-5172, a selective inhibitor of hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants
-
Summa V, Ludmerer S W, McCauley JA, et al. MK-5172, a selective inhibitor of hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants. Antimicrob Agents Chemother. 2012;56(8):4161-4167.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, Issue.8
, pp. 4161-4167
-
-
Summa, V.1
Ludmerer, S.W.2
McCauley, J.A.3
-
83
-
-
33646015668
-
The non-immunosuppressive cyclosporin DEBIO-025 is a potent inhibitor of hepatitis C virus replication in vitro
-
Paeshuyse J, Kaul A, De Clercq E, et al. The non-immunosuppressive cyclosporin DEBIO-025 is a potent inhibitor of hepatitis C virus replication in vitro. Hepatology. 2006;43(4):761-770.
-
(2006)
Hepatology
, vol.43
, Issue.4
, pp. 761-770
-
-
Paeshuyse, J.1
Kaul, A.2
de Clercq, E.3
-
84
-
-
84861188748
-
Antiviral activity of TMC435 mono-therapy in patients infected with HCV genotypes 2-6: TMC435-C202, a phase IIa, open-label study
-
Moreno C, Berg T, Tanwandee T, et al. Antiviral activity of TMC435 mono-therapy in patients infected with HCV genotypes 2-6: TMC435-C202, a phase IIa, open-label study. J Hepatol. 2012;56(6):1247-1253.
-
(2012)
J Hepatol
, vol.56
, Issue.6
, pp. 1247-1253
-
-
Moreno, C.1
Berg, T.2
Tanwandee, T.3
-
85
-
-
84863650706
-
SVR12 among G1/4 treatement naive patients receiving mericitabine in combination with PEG-IFN alfa-2a/ ribavirin; Interim analysis from the JUMP-C study [abstract]
-
Pockros P, Jensen D, Tsai N, et al. SVR12 among G1/4 treatement naive patients receiving mericitabine in combination with PEG-IFN alfa-2a/ ribavirin; Interim analysis from the JUMP-C study [abstract]. J Hepatol. 2012;56(Suppl 2):S477-S478.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Pockros, P.1
Jensen, D.2
Tsai, N.3
-
86
-
-
84863703699
-
ATOMIC: 97% RVR for PSI-7977 + PEG/RBV × 12 week regimen in HCV GT1: An end to response-guided therapy [abstract]?
-
Kowdley K V, Lawitz E, Crespo I, et al. ATOMIC: 97% RVR for PSI-7977 + PEG/RBV × 12 week regimen in HCV GT1: an end to response-guided therapy [abstract]? J Hepatol. 2012;56(Suppl 2):S1.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Kowdley, K.V.1
Lawitz, E.2
Crespo, I.3
-
87
-
-
84871206253
-
Safety and effcacy of telaprevir or boceprevir in combination with peginterferon alfa/ribavirin in 455 cirrhotic non responders. Week 16 analysis of the French early access program (ANRS CO20-CUPIC) in real-life setting [abstract]
-
Hezode C, Dorival C, Zoulim F, et al. Safety and effcacy of telaprevir or boceprevir in combination with peginterferon alfa/ribavirin in 455 cirrhotic non responders. Week 16 analysis of the French early access program (ANRS CO20-CUPIC) in real-life setting [abstract]. Hepatolog y. 2012;56(Suppl):217A.
-
(2012)
Hepatolog Y
, vol.56
, Issue.SUPPL.
-
-
Hezode, C.1
Dorival, C.2
Zoulim, F.3
-
88
-
-
84868104783
-
Effcacy and safety of protease inhibitors for severe hepatitis C recurrence after liver transplantation: A frst multicentric experience [abstract]
-
Coilly A, Roche B, Botta-Fridlund D, et al. Effcacy and safety of protease inhibitors for severe hepatitis C recurrence after liver transplantation: A frst multicentric experience [abstract]. J Hepatol. 2012; 56(Suppl 2):S21.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Coilly, A.1
Roche, B.2
Botta-Fridlund, D.3
-
89
-
-
84872042782
-
How to optimize HCV therapy in genotype 1 patients with cirrhosis
-
Bourliere M, Wendt A, Fontaine H, Hezode C, Pol S, Bronowicki J P. How to optimize HCV therapy in genotype 1 patients with cirrhosis. Liver Int. 2013;33(Suppl 1):46-55.
-
(2013)
Liver Int
, vol.33
, Issue.SUPPL. 1
, pp. 46-55
-
-
Bourliere, M.1
Wendt, A.2
Fontaine, H.3
Hezode, C.4
Pol, S.5
Bronowicki, J.P.6
-
90
-
-
84872045267
-
The effect of hepatic impairment on the pharmacokinetics and antiviral activity of PSI-7977 in hepatitis C infected subjects treated for seven days [abstract]
-
Lawitz E, Rodriguez-Torres M, Cornpropst MT, et al. The effect of hepatic impairment on the pharmacokinetics and antiviral activity of PSI-7977 in hepatitis C infected subjects treated for seven days [abstract]. J Hepatol. 2012;56(Suppl 2):S445-S446.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Lawitz, E.1
Rodriguez-Torres, M.2
Cornpropst, M.T.3
-
91
-
-
84878128350
-
Effcacy and safety of the interferon-free combination of BI 201335 + BI 207127 with or without ribavirin in treatment-naive patients with HCV genotype 1 infection and compensated liver cirrhosis: Results from the SOUND-C2 study [abstract]
-
Soriano V, Gane EJ, Angus P W, et al. Effcacy and safety of the interferon-free combination of BI 201335 + BI 207127 with or without ribavirin in treatment-naive patients with HCV genotype 1 infection and compensated liver cirrhosis: results from the SOUND-C2 study [abstract]. Hepatology. 2012;56(Suppl 1):234A.
-
(2012)
Hepatology
, vol.56
, Issue.SUPPL. 1
-
-
Soriano, V.1
Gane, E.J.2
Angus, P.W.3
-
92
-
-
84888884057
-
12 weeks response- guided treatment with the NS5A inhibitor, GS-5885, the NS3 protease inhibitor, GS-9451, plus pegylated interferon and ribavirin in treatment naive genotype 1 hepatitis C infected patients
-
Marcellin P, Manns M, Janczewska E, et al. 12 weeks response- guided treatment with the NS5A inhibitor, GS-5885, the NS3 protease inhibitor, GS-9451, plus pegylated interferon and ribavirin in treatment naive genotype 1 hepatitis C infected patients. J Hepatol. 2013;58(2):S355.
-
(2013)
J Hepatol
, vol.58
, Issue.2
-
-
Marcellin, P.1
Manns, M.2
Janczewska, E.3
-
93
-
-
84881314421
-
GS-5885 + GS- 9451 + PEGinterferon and ribavirin for six or twelve weeks achieves high SVR12 rates in treatment naive genotype1 IL28B CC patients
-
Thompson A, Han S, Shiffman M, et al. (2013) GS-5885 + GS- 9451 + PEGinterferon and ribavirin for six or twelve weeks achieves high SVR12 rates in treatment naive genotype1 IL28B CC patients. J Hepatol. 2013;58(2):S29.
-
(2013)
J Hepatol. 2013
, vol.58
, Issue.2
-
-
Thompson, A.1
Han, S.2
Shiffman, M.3
-
94
-
-
84892168710
-
Combination of the NS5A inhibitor GS-5885, the NS3 protease inhibitor GS-9451 and pegylated interferon plus riba- virin in treatment experienced patients with genotype 1 hepatitis C infection
-
Everson G, Di Bisceglie A, Vierling J, et al. (2013) Combination of the NS5A inhibitor GS-5885, the NS3 protease inhibitor GS-9451 and pegylated interferon plus riba- virin in treatment experienced patients with genotype 1 hepatitis C infection. J Hepatol. 58(2):S6.
-
(2013)
J Hepatol
, vol.58
, Issue.2
-
-
Everson, G.1
Di Bisceglie, A.2
Vierling, J.3
-
95
-
-
84892186761
-
SVR4 results of a once daily regimen of simeprevir (TMC-435) plus sofosbuvir (GS-7977) with or without ribavirin in HCV GT-1 null respon- ders. DDW Orlando May 18-21, 2013
-
Abstract Sa
-
Lawitz E, Ghalib R, Rodriguez-Torres M. SVR4 results of a once daily regimen of simeprevir (TMC-435) plus sofosbuvir (GS-7977) with or without ribavirin in HCV GT-1 null respon- ders. DDW Orlando May 18-21, 2013. Gastroenterology. Abstract Sa 2013;144(1):374-375.
-
(2013)
Gastroenterology
, vol.144
, Issue.1
, pp. 374-375
-
-
Lawitz, E.1
Ghalib, R.2
Rodriguez-Torres, M.3
-
96
-
-
84879198467
-
Simeprevir (TMC 435) with PEGinterferon/ribavirin for treatment of chronic HCV genotype-1 infection in treat-ment-naive patients: Results from Quest -2. A phase III trial
-
Manns M, Marcellin P, Poordad F, De Araujo E, Buti M, Horsmans Y, et al. Simeprevir (TMC 435) with PEGinterferon/ribavirin for treatment of chronic HCV genotype-1 infection in treat-ment-naive patients: results from Quest -2. A phase III trial. J Hepatol. 2013;58(Suppl 1): S568.
-
(2013)
J Hepatol
, vol.58
, Issue.SUPPL. 1
-
-
Manns, M.1
Marcellin, P.2
Poordad, F.3
de Araujo, E.4
Buti, M.5
Horsmans, Y.6
-
97
-
-
84879198467
-
Simeprevir (TMC 435) with PEGinterferon/ribavirin for chronic HCV geno- type-1 infection in treatment naive patients: Results from Quest-1, a phase III trial
-
98
-
Jacobson I, Dore G, Foster G, Fried M, Radu M, Rafalskiy V, et al. Simeprevir (TMC 435) with PEGinterferon/ribavirin for chronic HCV geno- type-1 infection in treatment naive patients: results from Quest-1, a phase III trial. J Hepatol. 2013;58(Suppl 1):S574.98.
-
(2013)
J Hepatol
, vol.58
, Issue.SUPPL. 1
-
-
Jacobson, I.1
Dore, G.2
Foster, G.3
Fried, M.4
Radu, M.5
Rafalskiy, V.6
-
98
-
-
84870398673
-
TMC435 in HCV genotype 1 patients who have failed previous pegylated interferon ribavirin treatment: Final SVR24 results of the ASPIRE trial
-
Zeuzem S, Berg T, Gane E et al. TMC435 in HCV genotype 1 patients who have failed previous pegylated interferon ribavirin treatment: final SVR24 results of the ASPIRE trial. J Hepatol. 2012;56(Suppl 2):S1.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Zeuzem, S.1
Berg, T.2
Gane, E.3
-
99
-
-
84878976866
-
Sofosbuvir with pegylated interferon alfa-2a and ribavirin for treat- ment-naive patients with hepatitis C genotype-1 infection (ATOMIC): An open-label, randomised, multicentre phase 2 trial
-
Kowdley K, Lawitz E, Crespo I, et al. Sofosbuvir with pegylated interferon alfa-2a and ribavirin for treat- ment-naive patients with hepatitis C genotype-1 infection (ATOMIC): an open-label, randomised, multicentre phase 2 trial. Lancet. 2013;381:2100-2107.
-
(2013)
Lancet
, vol.381
, pp. 2100-2107
-
-
Kowdley, K.1
Lawitz, E.2
Crespo, I.3
-
100
-
-
84869837557
-
PSI-7977 proton and electron: 100% concordance of SV4 with SVR24 in HCV GT1, GT2 and GT3
-
Lawitz E, Gane E, Stedman C, et al. PSI-7977 proton and electron: 100% concordance of SV4 with SVR24 in HCV GT1, GT2 and GT3. J Hepatol. 2012;56(Suppl 2):S4.
-
(2012)
J Hepatol
, vol.56
, Issue.SUPPL. 2
-
-
Lawitz, E.1
Gane, E.2
Stedman, C.3
-
101
-
-
84876740954
-
Sofosbuvir in combination with peginterferon alfa-2a and ribavirin for non-cirrhotic, treatment-naive patients with geno- types 1, 2, and 3 hepatitis C infection: A randomised, double-blind, phase 2 trial
-
Lawitz E, Lalezari J, Hassanein T, et al. Sofosbuvir in combination with peginterferon alfa-2a and ribavirin for non-cirrhotic, treatment-naive patients with geno- types 1, 2, and 3 hepatitis C infection: a randomised, double-blind, phase 2 trial. Lancet Infect Dis13. 2013:401-408.
-
(2013)
Lancet Infect Dis13
, pp. 401-408
-
-
Lawitz, E.1
Lalezari, J.2
Hassanein, T.3
-
102
-
-
84877730954
-
Sofosbuvir for previously untreated chronic hepatitis C infection
-
Lawitz E, Mangia A, Wyles D, et al. Sofosbuvir for previously untreated chronic hepatitis C infection. N Engl J Med. 2013. 368:1878-1887.
-
(2013)
N Engl J Med
, vol.368
, pp. 1878-1887
-
-
Lawitz, E.1
Mangia, A.2
Wyles, D.3
-
103
-
-
84880964894
-
Sofosbuvir (GS-7977) plus peginterferon/ribavirin in treatment-naive patients with HCV genotype 1: A randomized, 28-day, dose-ranging trial
-
Rodriguez-Torres M, Lawitz E, Kowdley K, et al. Sofosbuvir (GS-7977) plus peginterferon/ribavirin in treatment-naive patients with HCV genotype 1: a randomized, 28-day, dose-ranging trial. J Hepatol. 2013:58:663-668.
-
(2013)
J Hepatol
, vol.58
, pp. 663-668
-
-
Rodriguez-Torres, M.1
Lawitz, E.2
Kowdley, K.3
-
104
-
-
84871814966
-
Nucleotide polymerase inhibitor sofosbuvir plus riba- virin for hepatitis C
-
Gane E, Stedman C, Hyland R, et al. Nucleotide polymerase inhibitor sofosbuvir plus riba- virin for hepatitis C. N Engl J Med. 2013;368: 34-44.
-
(2013)
N Engl J Med
, vol.368
, pp. 34-44
-
-
Gane, E.1
Stedman, C.2
Hyland, R.3
-
105
-
-
84880271996
-
All-oral sofosbuvir- based 12 week regimen for the treatment of chronic HCV infection: The Electron study
-
Gane E, Stedman C, Hyland R, et al. All-oral sofosbuvir- based 12 week regimen for the treatment of chronic HCV infection: the Electron study. J Hepatol. 2013;58(Suppl. 1):S6-S7.
-
(2013)
J Hepatol
, vol.58
, Issue.SUPPL. 1
-
-
Gane, E.1
Stedman, C.2
Hyland, R.3
-
106
-
-
84890635280
-
SVR4 results of a once daily regimen of simeprevir (TMC-435) plus sofosbuvir (GS-7977) with or without ribavirin in HCV GT-1 null respon-ders
-
Lawitz, E, Ghalib R, Rodriguez-Torres M. SVR4 results of a once daily regimen of simeprevir (TMC-435) plus sofosbuvir (GS-7977) with or without ribavirin in HCV GT-1 null respon-ders. DDW Orlando. 2013;18-21.
-
(2013)
DDW Orlando
, pp. 18-21
-
-
Lawitz, E.1
Ghalib, R.2
Rodriguez-Torres, M.3
-
107
-
-
84888884057
-
12 weeks response-guided treatment with the NS5A inhibitor, GS-5885, the NS3 protease inhibitor, GS-9451, plus pegylated interferon and ribavirin in treatment naive genotype 1 hepatitis C infected patients
-
Marcellin P, Manns M, Janczewska E, et al. 12 weeks response-guided treatment with the NS5A inhibitor, GS-5885, the NS3 protease inhibitor, GS-9451, plus pegylated interferon and ribavirin in treatment naive genotype 1 hepatitis C infected patients. J Hepatol. 2013;58(Suppl 2): S355.
-
(2013)
J Hepatol
, vol.58
, Issue.SUPPL. 2
-
-
Marcellin, P.1
Manns, M.2
Janczewska, E.3
-
108
-
-
84881314421
-
GS-5885 {thorn} GS- 9451 {thorn} PEG interferon and ribavirin for six or twelve weeks achieves high SVR12 rates in treatment naive genotype 1 IL28B CC patients
-
Thompson A, Han S, Shiffman M, et al. GS-5885 {thorn} GS- 9451 {thorn} PEG interferon and ribavirin for six or twelve weeks achieves high SVR12 rates in treatment naive genotype 1 IL28B CC patients. J Hepatol. 2013;58(Suppl 2):S29.
-
(2013)
J Hepatol
, vol.58
, Issue.SUPPL. 2
-
-
Thompson, A.1
Han, S.2
Shiffman, M.3
-
109
-
-
84892168710
-
Combination of the NS5A inhibitor GS-5885, the NS3 protease inhibitor GS-9451 and pegylated interferon plus riba-virin in treatment experienced patients with genotype 1 hepatitis C infection
-
Everson G, Di Bisceglie A, Vierling J, et al. Combination of the NS5A inhibitor GS-5885, the NS3 protease inhibitor GS-9451 and pegylated interferon plus riba-virin in treatment experienced patients with genotype 1 hepatitis C infection. J Hepatol. 2013;58(Suppl 2):S6.
-
(2013)
J Hepatol
, vol.58
, Issue.SUPPL. 2
-
-
Everson, G.1
Di Bisceglie, A.2
Vierling, J.3
-
110
-
-
84863678711
-
Potent viral suppression with the all-oral combination of daclatas-vir (NS5A inhibitor) and GS-7977 (nucleotide NS5B inhibitor {thorn}/- ribavirin in treatment-naive patients with chronic HCV GT1,2, or 3
-
Sulkowski M, Gardiner D, Lawitz E, et al. Potent viral suppression with the all-oral combination of daclatas-vir (NS5A inhibitor) and GS-7977 (nucleotide NS5B inhibitor {thorn}/- ribavirin in treatment-naive patients with chronic HCV GT1,2, or 3. J Hepatol. 2012;56:S560.
-
(2012)
J Hepatol
, vol.56
-
-
Sulkowski, M.1
Gardiner, D.2
Lawitz, E.3
-
111
-
-
84880292800
-
Sustained virologic response with daclatasvir plus sofosbuvir with or without ribavirin in chronic HCV genotype 1 infected patients who previously failed tel-aprevir or borceprevir
-
Sulkowski M, Gardiner D, Rodriguez-Torres M, et al. Sustained virologic response with daclatasvir plus sofosbuvir with or without ribavirin in chronic HCV genotype 1 infected patients who previously failed tel-aprevir or borceprevir. J Hepatol. 2013;58(Suppl 2): S570.
-
(2013)
J Hepatol
, vol.58
, Issue.SUPPL. 2
-
-
Sulkowski, M.1
Gardiner, D.2
Rodriguez-Torres, M.3
|