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Volumn 8, Issue 12, 2013, Pages 1492-1501

Contributions of KRAS and RAL in non-small-cell lung cancer growth and progression

Author keywords

GTPase; Non small cell lung cancer; Prognosis; RAL; RAS

Indexed keywords

GLYCINE; K RAS PROTEIN; RAL PROTEIN; KRAS PROTEIN, HUMAN; MESSENGER RNA; ONCOPROTEIN; RALA PROTEIN, HUMAN; RALB PROTEIN, HUMAN; RAS PROTEIN;

EID: 84892146436     PISSN: 15560864     EISSN: 15561380     Source Type: Journal    
DOI: 10.1097/JTO.0000000000000007     Document Type: Article
Times cited : (40)

References (24)
  • 2
    • 0037805547 scopus 로고    scopus 로고
    • RAS oncogenes: The first 30 years
    • Malumbres M, Barbacid M. RAS oncogenes: the first 30 years. Nat Rev Cancer 2003;3:459-465.
    • (2003) Nat Rev Cancer , vol.3 , pp. 459-465
    • Malumbres, M.1    Barbacid, M.2
  • 3
    • 77956805993 scopus 로고    scopus 로고
    • KRAS gene mutations in lung cancer: Particulars established and issues unresolved
    • Okudela K, Woo T, Kitamura H. KRAS gene mutations in lung cancer: particulars established and issues unresolved. Pathol Int 2010;60:651-660.
    • (2010) Pathol Int , vol.60 , pp. 651-660
    • Okudela, K.1    Woo, T.2    Kitamura, H.3
  • 4
    • 65349107082 scopus 로고    scopus 로고
    • KRAS mutations in non-small cell lung cancer
    • Riely GJ, Marks J, Pao W. KRAS mutations in non-small cell lung cancer. Proc Am Thorac Soc 2009;6:201-205.
    • (2009) Proc Am Thorac Soc , vol.6 , pp. 201-205
    • Riely, G.J.1    Marks, J.2    Pao, W.3
  • 5
    • 77349091545 scopus 로고    scopus 로고
    • Biological and clinical significance of KRAS mutations in lung cancer: An oncogenic driver that contrasts with EGFR mutation
    • Suda K, Tomizawa K, Mitsudomi T. Biological and clinical significance of KRAS mutations in lung cancer: an oncogenic driver that contrasts with EGFR mutation. Cancer Metastasis Rev 2010;29:49-60.
    • (2010) Cancer Metastasis Rev , vol.29 , pp. 49-60
    • Suda, K.1    Tomizawa, K.2    Mitsudomi, T.3
  • 6
    • 0021362206 scopus 로고
    • Malignant activation of a K-ras oncogene in lung carcinoma but not in normal tissue of the same patient
    • Santos E, Martin-Zanca D, Reddy E P, Pierotti MA, Della Porta G, Barbacid M. Malignant activation of a K-ras oncogene in lung carcinoma but not in normal tissue of the same patient. Science 1984;223:661-664.
    • (1984) Science , vol.223 , pp. 661-664
    • Santos, E.1    Martin-Zanca, D.2    Reddy, E.P.3    Pierotti, M.A.4    Della Porta, G.5    Barbacid, M.6
  • 7
  • 9
    • 19944430434 scopus 로고    scopus 로고
    • The role of RAS oncogene in survival of patients with lung cancer: A systematic review of the literature with meta-analysis
    • Mascaux C, Iannino N, Martin B, et al. The role of RAS oncogene in survival of patients with lung cancer: a systematic review of the literature with meta-analysis. Br J Cancer 2005;92:131-139.
    • (2005) Br J Cancer , vol.92 , pp. 131-139
    • Mascaux, C.1    Iannino, N.2    Martin, B.3
  • 10
    • 33845448647 scopus 로고    scopus 로고
    • Divergent roles for RalA and RalB in malignant growth of human pancreatic carcinoma cells
    • Lim KH, O'Hayer K, Adam SJ, et al. Divergent roles for RalA and RalB in malignant growth of human pancreatic carcinoma cells. Curr Biol 2006;16:2385-2394.
    • (2006) Curr Biol , vol.16 , pp. 2385-2394
    • Lim, K.H.1    O'Hayer, K.2    Adam, S.J.3
  • 11
    • 35648970538 scopus 로고    scopus 로고
    • Activation of the RalGEF/ral pathway promotes prostate cancer metastasis to bone
    • Yin J, Pollock C, Tracy K, et al. Activation of the RalGEF/Ral pathway promotes prostate cancer metastasis to bone. Mol Cell Biol 2007;27:7538-7550.
    • (2007) Mol Cell Biol , vol.27 , pp. 7538-7550
    • Yin, J.1    Pollock, C.2    Tracy, K.3
  • 14
    • 38849147752 scopus 로고    scopus 로고
    • Ral GTPases and cancer: Linchpin support of the tumorigenic platform
    • Bodemann BO, White MA. Ral GTPases and cancer: linchpin support of the tumorigenic platform. Nat Rev Cancer 2008;8:133-140.
    • (2008) Nat Rev Cancer , vol.8 , pp. 133-140
    • Bodemann, B.O.1    White, M.A.2
  • 15
    • 84868593574 scopus 로고    scopus 로고
    • Genetic deletion of RALA and RALB small GTPases reveals redundant functions in development and tumorigenesis
    • Peschard P, McCarthy A, Leblanc-Dominguez V, et al. Genetic deletion of RALA and RALB small GTPases reveals redundant functions in development and tumorigenesis. Curr Biol 2012;22:2063-2068.
    • (2012) Curr Biol , vol.22 , pp. 2063-2068
    • Peschard, P.1    McCarthy, A.2    Leblanc-Dominguez, V.3
  • 16
    • 84863116014 scopus 로고    scopus 로고
    • Effect of KRAS oncogene substitutions on protein behavior: Implications for signaling and clinical outcome
    • Ihle NT, Byers LA, Kim ES, et al. Effect of KRAS oncogene substitutions on protein behavior: implications for signaling and clinical outcome. J Natl Cancer Inst 2012;104:228-239.
    • (2012) J Natl Cancer Inst , vol.104 , pp. 228-239
    • Ihle, N.T.1    Byers, L.A.2    Kim, E.S.3
  • 17
    • 23844472876 scopus 로고    scopus 로고
    • RalA and RalB: Antagonistic relatives in cancer cell migration
    • Oxford G, Owens CR, Titus BJ, et al. RalA and RalB: antagonistic relatives in cancer cell migration. Cancer Res 2005;65:7111-7120.
    • (2005) Cancer Res , vol.65 , pp. 7111-7120
    • Oxford, G.1    Owens, C.R.2    Titus, B.J.3
  • 18
    • 84865202387 scopus 로고    scopus 로고
    • 3-phosphoinositide-dependent kinase 1 controls breast tumor growth in a kinase-dependent but akt-independent manner
    • Gagliardi PA, di Blasio L, Orso F, et al. 3-phosphoinositide-dependent kinase 1 controls breast tumor growth in a kinase-dependent but Akt-independent manner. Neoplasia 2012;14:719-731.
    • (2012) Neoplasia , vol.14 , pp. 719-731
    • Gagliardi, P.A.1    Di Blasio, L.2    Orso, F.3
  • 20
    • 0041846652 scopus 로고    scopus 로고
    • Ral-GTPases: Approaching their 15 minutes of fame
    • Feig LA. Ral-GTPases: approaching their 15 minutes of fame. Trends Cell Biol 2003;13:419-425.
    • (2003) Trends Cell Biol , vol.13 , pp. 419-425
    • Feig, L.A.1
  • 21
    • 84863911673 scopus 로고    scopus 로고
    • Transcriptional signatures of ral GTPase are associated with aggressive clinicopathologic characteristics in human cancer
    • Smith SC, Baras AS, Owens CR, Dancik G, Theodorescu D. Transcriptional signatures of Ral GTPase are associated with aggressive clinicopathologic characteristics in human cancer. Cancer Res 2012;72:3480-3491.
    • (2012) Cancer Res , vol.72 , pp. 3480-3491
    • Smith, S.C.1    Baras, A.S.2    Owens, C.R.3    Dancik, G.4    Theodorescu, D.5
  • 22
    • 0031472912 scopus 로고    scopus 로고
    • Colocalization of ras and ral on the membrane is required for rasdependent ral activation through ral GDP dissociation stimulator
    • Kishida S, Koyama S, Matsubara K, Kishida M, Matsuura Y, Kikuchi A. Colocalization of Ras and Ral on the membrane is required for Rasdependent Ral activation through Ral GDP dissociation stimulator. Oncogene 1997;15:2899-2907.
    • (1997) Oncogene , vol.15 , pp. 2899-2907
    • Kishida, S.1    Koyama, S.2    Matsubara, K.3    Kishida, M.4    Matsuura, Y.5    Kikuchi, A.6
  • 23
    • 0033545328 scopus 로고    scopus 로고
    • Plasma membrane recruitment of RalGDS is critical for ras-dependent ral activation
    • Matsubara K, Kishida S, Matsuura Y, Kitayama H, Noda M, Kikuchi A. Plasma membrane recruitment of RalGDS is critical for Ras-dependent Ral activation. Oncogene 1999;18:1303-1312.
    • (1999) Oncogene , vol.18 , pp. 1303-1312
    • Matsubara, K.1    Kishida, S.2    Matsuura, Y.3    Kitayama, H.4    Noda, M.5    Kikuchi, A.6
  • 24
    • 65649108558 scopus 로고    scopus 로고
    • A gene expression signature associated with "K-ras addiction" reveals regulators of EMT and tumor cell survival
    • Singh A, Greninger P, Rhodes D, et al. A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival. Cancer Cell 2009;15:489-500.
    • (2009) Cancer Cell , vol.15 , pp. 489-500
    • Singh, A.1    Greninger, P.2    Rhodes, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.