-
1
-
-
0022779153
-
The ral gene: A new ras related gene isolated by the use of a synthetic probe
-
Chardin P, Tavitian A. The ral gene: a new ras related gene isolated by the use of a synthetic probe. EMBO J 1986;5:2203-8.
-
(1986)
EMBO J
, vol.5
, pp. 2203-2208
-
-
Chardin, P.1
Tavitian, A.2
-
2
-
-
0030022174
-
Ral-GTPases mediate a distinct downstream signaling pathway from Ras that facilitates cellular transformation
-
Urano T, Emkey R, Feig LA. Ral-GTPases mediate a distinct downstream signaling pathway from Ras that facilitates cellular transformation. EMBO J 1996;15:810-6.
-
(1996)
EMBO J
, vol.15
, pp. 810-816
-
-
Urano, T.1
Emkey, R.2
Feig, L.A.3
-
4
-
-
0033029811
-
Ras caught in another affair: The exchange factors for Ral
-
Wolthuis RM, Bos JL. Ras caught in another affair: the exchange factors for Ral. Curr Opin Genet Dev 1999;9:112-7.
-
(1999)
Curr Opin Genet Dev
, vol.9
, pp. 112-117
-
-
Wolthuis, R.M.1
Bos, J.L.2
-
5
-
-
20444393402
-
Ral GTPases: Corrupting the exocyst in cancer cells
-
Camonis JH, White MA. Ral GTPases: corrupting the exocyst in cancer cells. Trends Cell Biol 2005;15:327-32.
-
(2005)
Trends Cell Biol
, vol.15
, pp. 327-332
-
-
Camonis, J.H.1
White, M.A.2
-
6
-
-
20444410041
-
Activation of RalA is critical for Ras-induced tumorigenesis of human cells
-
Lim KH, Baines AT, Fiordalisi JJ, et al. Activation of RalA is critical for Ras-induced tumorigenesis of human cells. Cancer Cell 2005;7: 533-45.
-
(2005)
Cancer Cell
, vol.7
, pp. 533-545
-
-
Lim, K.H.1
Baines, A.T.2
Fiordalisi, J.J.3
-
7
-
-
0041846652
-
Ral-GTPases: Approaching their 15 minutes of fame
-
Feig LA. Ral-GTPases: approaching their 15 minutes of fame. Trends Cell Biol 2003;13:419-25.
-
(2003)
Trends Cell Biol
, vol.13
, pp. 419-425
-
-
Feig, L.A.1
-
9
-
-
30644463689
-
RalB mobilizes the exocyst to drive cell migration
-
Rosse C, Hatzoglou A, Parrini MC, White MA, Chavrier P, Camonis J. RalB mobilizes the exocyst to drive cell migration. Mol Cell Biol 2006; 26:727-34.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 727-734
-
-
Rosse, C.1
Hatzoglou, A.2
Parrini, M.C.3
White, M.A.4
Chavrier, P.5
Camonis, J.6
-
10
-
-
23844472876
-
RalA and RalB: Antagonistic relatives in cancer cell migration
-
Oxford G, Owens CR, Titus BJ, et al. RalA and RalB: antagonistic relatives in cancer cell migration. Cancer Res 2005;65:7111-20.
-
(2005)
Cancer Res
, vol.65
, pp. 7111-7120
-
-
Oxford, G.1
Owens, C.R.2
Titus, B.J.3
-
11
-
-
35648970538
-
Activation of the RalGEF/Ral pathway promotes prostate cancer metastasis to bone
-
Yin J, Pollock C, Tracy K, et al. Activation of the RalGEF/Ral pathway promotes prostate cancer metastasis to bone. Mol Cell Biol 2007;27: 7538-50.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 7538-7550
-
-
Yin, J.1
Pollock, C.2
Tracy, K.3
-
12
-
-
33845448647
-
Divergent roles for RalA and RalB in malignant growth of human pancreatic carcinoma cells
-
Lim KH, O'Hayer K, Adam SJ, et al. Divergent roles for RalA and RalB in malignant growth of human pancreatic carcinoma cells. Curr Biol 2006;16:2385-94.
-
(2006)
Curr Biol
, vol.16
, pp. 2385-2394
-
-
Lim, K.H.1
O'Hayer, K.2
Adam, S.J.3
-
13
-
-
13244256872
-
The small G-protein RalA stimulates metastasis of transformed cells
-
Tchevkina E, Agapova L, Dyakova N, Martinjuk A, Komelkov A, Tatosyan A. The small G-protein RalA stimulates metastasis of transformed cells. Oncogene 2005;24:329-35.
-
(2005)
Oncogene
, vol.24
, pp. 329-335
-
-
Tchevkina, E.1
Agapova, L.2
Dyakova, N.3
Martinjuk, A.4
Komelkov, A.5
Tatosyan, A.6
-
14
-
-
0034899045
-
Signal pathways which promote invasion and metastasis: Critical and distinct contributions of extracellular signal-regulated kinase and Ral-specific guanine exchange factor pathways
-
Ward Y, Wang W, Woodhouse E, Linnoila I, Liotta L, Kelly K. Signal pathways which promote invasion and metastasis: critical and distinct contributions of extracellular signal-regulated kinase and Ral-specific guanine exchange factor pathways. Mol Cell Biol 2001;21:5958-69.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 5958-5969
-
-
Ward, Y.1
Wang, W.2
Woodhouse, E.3
Linnoila, I.4
Liotta, L.5
Kelly, K.6
-
15
-
-
38849147752
-
Ral GTPases and cancer: Linchpin support of the tumorigenic platform
-
Bodemann BO, White MA. Ral GTPases and cancer: linchpin support of the tumorigenic platform. Nat Rev Cancer 2008;8:133-40.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 133-140
-
-
Bodemann, B.O.1
White, M.A.2
-
16
-
-
0042353628
-
RAL GTPases are linchpin modulators of human tumour-cell proliferation and survival
-
Chien Y, White MA. RAL GTPases are linchpin modulators of human tumour-cell proliferation and survival. EMBO Rep 2003;4:800-6.
-
(2003)
EMBO Rep
, vol.4
, pp. 800-806
-
-
Chien, Y.1
White, M.A.2
-
17
-
-
36048968159
-
Geranylgeranyltransferase I inhibitors target RalB to inhibit anchorage-dependent growth and induce apoptosis and RalA to inhibit anchorage-independent growth
-
Falsetti SC, Wang DA, Peng H, et al. Geranylgeranyltransferase I inhibitors target RalB to inhibit anchorage-dependent growth and induce apoptosis and RalA to inhibit anchorage-independent growth. Mol Cell Biol 2007;27:8003-14.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 8003-8014
-
-
Falsetti, S.C.1
Wang, D.A.2
Peng, H.3
-
18
-
-
2942711520
-
RalA but not RalB enhances polarized delivery of membrane proteins to the basolateral surface of epithelial cells
-
Shipitsin M, Feig LA. RalA but not RalB enhances polarized delivery of membrane proteins to the basolateral surface of epithelial cells. Mol Cell Biol 2004;24:5746-56.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 5746-5756
-
-
Shipitsin, M.1
Feig, L.A.2
-
19
-
-
20144373746
-
Identification of V23RalA-Ser194 as a critical mediator for Aurora-A-induced cellular motility and transformation by small pool expression screening
-
Wu JC, Chen TY, Yu CT, et al. Identification of V23RalA-Ser194 as a critical mediator for Aurora-A-induced cellular motility and transformation by small pool expression screening. J Biol Chem 2005;280: 9013-22.
-
(2005)
J Biol Chem
, vol.280
, pp. 9013-9022
-
-
Wu, J.C.1
Chen, T.Y.2
Yu, C.T.3
-
20
-
-
34249291096
-
The tumor suppressor PP2A Aβ regulates the RalA GTPase
-
Sablina AA, Chen W, Arroyo JD, et al. The tumor suppressor PP2A Aβ regulates the RalA GTPase. Cell 2007;129:969-82.
-
(2007)
Cell
, vol.129
, pp. 969-982
-
-
Sablina, A.A.1
Chen, W.2
Arroyo, J.D.3
-
21
-
-
73549119929
-
Aurora-A phosphorylates, activates, and relocalizes the small GTPase RalA
-
Lim KH, Brady DC, Kashatus DF, et al. Aurora-A phosphorylates, activates, and relocalizes the small GTPase RalA. Mol Cell Biol 2010; 30:508-23.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 508-523
-
-
Lim, K.H.1
Brady, D.C.2
Kashatus, D.F.3
-
22
-
-
0017184335
-
Binding of adenosine 3′,5′-monophosphate dependent protein kinase regulatory subunit to immobilized cyclic nucleotide derivatives
-
Dills WL, Jr., Beavo JA, Bechtel PJ, Myers KR, Sakai LJ, Krebs EG. Binding of adenosine 3′,5′-monophosphate dependent protein kinase regulatory subunit to immobilized cyclic nucleotide derivatives. Biochemistry 1976;15:3724-31.
-
(1976)
Biochemistry
, vol.15
, pp. 3724-3731
-
-
Dills Jr., W.L.1
Beavo, J.A.2
Bechtel, P.J.3
Myers, K.R.4
Sakai, L.J.5
Krebs, E.G.6
-
23
-
-
0035800812
-
Histamine-induced vasoconstriction involves phosphorylation of a specific inhibitor protein for myosin phosphatase by protein kinase C α and δ isoforms
-
Eto M, Kitazawa T, Yazawa M, Mukai H, Ono Y, Brautigan DL. Histamine-induced vasoconstriction involves phosphorylation of a specific inhibitor protein for myosin phosphatase by protein kinase C α and δ isoforms. J Biol Chem 2001;276:29072-8.
-
(2001)
J Biol Chem
, vol.276
, pp. 29072-29078
-
-
Eto, M.1
Kitazawa, T.2
Yazawa, M.3
Mukai, H.4
Ono, Y.5
Brautigan, D.L.6
-
24
-
-
2942590333
-
Activation of Aurora-A kinase by protein phosphatase inhibitor-2, a bifunctional signaling protein
-
Satinover DL, Leach CA, Stukenberg PT, Brautigan DL. Activation of Aurora-A kinase by protein phosphatase inhibitor-2, a bifunctional signaling protein. Proc Natl Acad Sci U S A 2004;101:8625-30.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 8625-8630
-
-
Satinover, D.L.1
Leach, C.A.2
Stukenberg, P.T.3
Brautigan, D.L.4
-
25
-
-
0036168098
-
The role of Ral A in epidermal growth factor receptor-regulated cell motility
-
Gildea JJ, Harding MA, Seraj MJ, Gulding KM, Theodorescu D. The role of Ral A in epidermal growth factor receptor-regulated cell motility. Cancer Res 2002;62:982-5.
-
(2002)
Cancer Res
, vol.62
, pp. 982-985
-
-
Gildea, J.J.1
Harding, M.A.2
Seraj, M.J.3
Gulding, K.M.4
Theodorescu, D.5
-
26
-
-
33846846542
-
Neuromedin U is regulated by the metastasis suppressor RhoGDI2 and is a novel promoter of tumor formation, lung metastasis and cancer cachexia
-
Wu Y, McRoberts K, Berr SS, Frierson HF, Jr., Conaway M, Theodorescu D. Neuromedin U is regulated by the metastasis suppressor RhoGDI2 and is a novel promoter of tumor formation, lung metastasis and cancer cachexia. Oncogene 2007;26:765-73.
-
(2007)
Oncogene
, vol.26
, pp. 765-773
-
-
Wu, Y.1
McRoberts, K.2
Berr, S.S.3
Frierson Jr., H.F.4
Conaway, M.5
Theodorescu, D.6
-
27
-
-
0032929056
-
Effect of phosphorylation on activities of Rap1A to interact with Raf-1 and to suppress Ras-dependent Raf-1 activation
-
Hu CD, Kariya K, Okada T, Qi X, Song C, Kataoka T. Effect of phosphorylation on activities of Rap1A to interact with Raf-1 and to suppress Ras-dependent Raf-1 activation. J Biol Chem 1999;274:48-51.
-
(1999)
J Biol Chem
, vol.274
, pp. 48-51
-
-
Hu, C.D.1
Kariya, K.2
Okada, T.3
Qi, X.4
Song, C.5
Kataoka, T.6
-
28
-
-
0025917451
-
Rap1A is a substrate for cyclic AMP-dependent protein kinase in human neutrophils
-
Quilliam LA, Mueller H, Bohl BP, et al. Rap1A is a substrate for cyclic AMP-dependent protein kinase in human neutrophils. J Immunol 1991;147:1628-35.
-
(1991)
J Immunol
, vol.147
, pp. 1628-1635
-
-
Quilliam, L.A.1
Mueller, H.2
Bohl, B.P.3
-
29
-
-
0027474508
-
Mutational analysis of the cAMP-dependent protein kinase-mediated phosphorylation site of Rap1b
-
Altschuler D, Lapetina EG. Mutational analysis of the cAMP-dependent protein kinase-mediated phosphorylation site of Rap1b. J Biol Chem 1993;268:7527-31.
-
(1993)
J Biol Chem
, vol.268
, pp. 7527-7531
-
-
Altschuler, D.1
Lapetina, E.G.2
-
30
-
-
0025823451
-
The cAMP-dependent protein kinase phosphorylates the rap1 protein in vitro as well as in intact fibroblasts, but not the closely related rap2 protein
-
Lerosey I, Pizon V, Tavitian A, de Gunzburg J. The cAMP-dependent protein kinase phosphorylates the rap1 protein in vitro as well as in intact fibroblasts, but not the closely related rap2 protein. Biochem Biophys Res Commun 1991;175:430-6.
-
(1991)
Biochem Biophys Res Commun
, vol.175
, pp. 430-436
-
-
Lerosey, I.1
Pizon, V.2
Tavitian, A.3
De Gunzburg, J.4
-
31
-
-
0030040750
-
Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes
-
Lang P, Gesbert F, Delespine-Carmagnat M, Stancou R, Pouchelet M, Bertoglio J. Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes. EMBO J 1996;15:510-9.
-
(1996)
EMBO J
, vol.15
, pp. 510-519
-
-
Lang, P.1
Gesbert, F.2
Delespine-Carmagnat, M.3
Stancou, R.4
Pouchelet, M.5
Bertoglio, J.6
-
32
-
-
0037081858
-
Phosphorylation states of Cdc42 and RhoA regulate their interactions with Rho GDP dissociation inhibitor and their extraction from biological membranes
-
Forget MA, Desrosiers RR, Gingras D, Beliveau R. Phosphorylation states of Cdc42 and RhoA regulate their interactions with Rho GDP dissociation inhibitor and their extraction from biological membranes. Biochem J 2002;361:243-54.
-
(2002)
Biochem J
, vol.361
, pp. 243-254
-
-
Forget, M.A.1
Desrosiers, R.R.2
Gingras, D.3
Beliveau, R.4
-
33
-
-
34250703569
-
Classical PKC isoforms in cancer
-
Martiny-Baron G, Fabbro D. Classical PKC isoforms in cancer. Pharmacol Res 2007;55:477-86.
-
(2007)
Pharmacol Res
, vol.55
, pp. 477-486
-
-
Martiny-Baron, G.1
Fabbro, D.2
-
35
-
-
33947603008
-
Protein kinase C and other diacylglycerol effectors in cancer
-
Griner EM, Kazanietz MG. Protein kinase C and other diacylglycerol effectors in cancer. Nat Rev Cancer 2007;7:281-94.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 281-294
-
-
Griner, E.M.1
Kazanietz, M.G.2
-
36
-
-
0025651192
-
Inhibition of invasion of invasive human bladder carcinoma cells by protein kinase C inhibitor staurosporine
-
Schwartz GK, Redwood SM, Ohnuma T, Holland JF, Droller MJ, Liu BC. Inhibition of invasion of invasive human bladder carcinoma cells by protein kinase C inhibitor staurosporine. J Natl Cancer Inst 1990; 82:1753-6.
-
(1990)
J Natl Cancer Inst
, vol.82
, pp. 1753-1756
-
-
Schwartz, G.K.1
Redwood, S.M.2
Ohnuma, T.3
Holland, J.F.4
Droller, M.J.5
Liu, B.C.6
-
37
-
-
0034899079
-
Protein kinase C signalling pathway is involved in the regulation of vascular endothelial growth factor expression in human bladder transitional carcinoma cells
-
Chabannes E, Fauconnet S, Bernardini S, Wallerand H, Adessi G, Bittard H. Protein kinase C signalling pathway is involved in the regulation of vascular endothelial growth factor expression in human bladder transitional carcinoma cells. Cell Signal 2001;13: 585-91.
-
(2001)
Cell Signal
, vol.13
, pp. 585-591
-
-
Chabannes, E.1
Fauconnet, S.2
Bernardini, S.3
Wallerand, H.4
Adessi, G.5
Bittard, H.6
-
38
-
-
33947212879
-
RalA regulates vascular endothelial growth factor-C (VEGF-C) synthesis in prostate cancer cells during androgen ablation
-
Rinaldo F, Li J, Wang E, Muders M, Datta K. RalA regulates vascular endothelial growth factor-C (VEGF-C) synthesis in prostate cancer cells during androgen ablation. Oncogene 2007;26:1731-8.
-
(2007)
Oncogene
, vol.26
, pp. 1731-1738
-
-
Rinaldo, F.1
Li, J.2
Wang, E.3
Muders, M.4
Datta, K.5
-
39
-
-
0035150233
-
High PKC α and low E-cadherin expression contribute to high migratory activity of colon carcinoma cells
-
Masur K, Lang K, Niggemann B, Zanker KS, Entschladen F. High PKC α and low E-cadherin expression contribute to high migratory activity of colon carcinoma cells. Mol Biol Cell 2001;12: 1973-82.
-
(2001)
Mol Biol Cell
, vol.12
, pp. 1973-1982
-
-
Masur, K.1
Lang, K.2
Niggemann, B.3
Zanker, K.S.4
Entschladen, F.5
-
40
-
-
4143112597
-
Protein kinase C α/β inhibitor Go6976 promotes formation of cell junctions and inhibits invasion of urinary bladder carcinoma cells
-
Koivunen J, Aaltonen V, Koskela S, Lehenkari P, Laato M, Peltonen J. Protein kinase C α/β inhibitor Go6976 promotes formation of cell junctions and inhibits invasion of urinary bladder carcinoma cells. Cancer Res 2004;64:5693-701.
-
(2004)
Cancer Res
, vol.64
, pp. 5693-5701
-
-
Koivunen, J.1
Aaltonen, V.2
Koskela, S.3
Lehenkari, P.4
Laato, M.5
Peltonen, J.6
|