Weak peristalsis with large breaks is associated with higher acid exposure and delayed reflux clearance in the supine position in GERD patients

American Journal of Gastroenterology

Volumn 109, Issue 1, 2014, Pages 46-51

  Ribolsi, Mentore ^a   Balestrieri, Paola ^a   Emerenziani, Sara ^a   Guarino, Michele Pier Luca ^a   Cicala, Michele ^a  

^a UNIVERSITY CAMPUS BIO MEDICO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACID EXPOSURE TIME; ADULT; ARTICLE; BOLUS CLEARING TIME; DISTAL CONTRACTILE INTEGRAL; ESOPHAGEAL PH MONITORING; ESOPHAGOSCOPY; ESOPHAGUS MANOMETRY; ESOPHAGUS MOTILITY; ESOPHAGUS PARAMETERS; FEMALE; FREQUENT FAILED PERISTALSIS; GASTROESOPHAGEAL REFLUX; HUMAN; MAJOR CLINICAL STUDY; MALE; NON EROSIVE REFLUX DISEASE; PRIORITY JOURNAL; REFLUX ESOPHAGITIS; STANDING; SUPINE POSITION; SWALLOWING; TOTAL BOLUS TRANSIT TIME; ESOPHAGUS; METABOLISM; MIDDLE AGED; PATHOLOGY; PATHOPHYSIOLOGY; PERISTALSIS; PHYSIOLOGY; SEVERITY OF ILLNESS INDEX; STATISTICS; STOMACH ACID; TIME;

ADULT; ESOPHAGEAL PH MONITORING; ESOPHAGUS; FEMALE; GASTRIC ACID; GASTROESOPHAGEAL REFLUX; HUMANS; MALE; MIDDLE AGED; PERISTALSIS; SEVERITY OF ILLNESS INDEX; STATISTICS AS TOPIC; SUPINE POSITION; TIME FACTORS;

EID: 84891954960     PISSN: 00029270     EISSN: 15720241     Source Type: Journal    
DOI: 10.1038/ajg.2013.373     Document Type: Article

References (27)

1. Kahrilas PJ, Dodds WJ, Hogan WJ et al. Esophageal peristaltic dysfunction in peptic esophagitis. Gastroenterology 1986;91:897-904
2. Olsen AM, Schlegel JF. Motility disturbances caused by esophagitis. J Th orac Cardiovasc Surg 1965;50:607-12
3. Leite LP, Johnston BT, Barrett J et al. Ineff ective esophageal motility (IEM): The primary fi nding in patients with nonspecifi c esophageal motility disorder. Dig Dis Sci 1997;42:1859-65
4. Savarino E, Gemignani L, Pohl D et al. Oesophageal motility and bolus transit abnormalities increase in parallel with the severity of gastrooesophageal refl ux disease. Aliment Pharmacol Ther 2011;34:476-86
5. Williams D, Th ompson DG, Heggie L et al. Esophageal clearance function following treatment of esophagitis. Gastroenterology 1994;106:108-16
6. Diener U, Patti MG, Molena D et al. Esophageal dysmotility and gastroesophageal refl ux disease. J Gastrointest Surg 2001;5:260-5
7. Fornari F, Blondeau K, Durand L et al. Relevance of mild ineff ective oesophageal motility (IOM) and potential pharmacological reversibility of severe IOM in patients with gastro-oesophageal refl ux disease. Aliment Pharmacol Ther 2007;26:1345-54
8. Fox M, Bredenoord AJ. Oesophageal high-resolution manometry: Moving from research into clinical practice. Gut 2008;57:405-23
9. Fox M, Hebbard G, Janiak P et al. High-resolution manometry predicts the success of oesophageal bolus transport and identifi es clinically important abnormalities not detected by conventional manometry. Neurogastroenterol Motil 2004;16:533-42 .
10. Bulsiewicz WJ, Kahrilas PJ, Kwiatek MA et al. Esophageal pressure topography criteria indicative of incomplete bolus clearance: A study using highresolution impedance manometry. Am J Gastroenterol 2009;104:2721-8
11. Roman S, Lin Z, Kwiatek MA et al. Weak peristalsis in esophageal pressure topography: Classifi cation and association with dysphagia. Am J Gastroenterol 2011;106:349-56
12. Bredenoord AJ, Fox M, Kahrilas PJ et al. Chicago classifi cation criteria of esophageal motility disorders defi ned in high resolution esophageal pressure topography. Neurogastroenterol Motil 2012;24 (Suppl 1):57-65
13. Xiao Y, Kahrilas PJ, Kwasny MJ et al. High-resolution manometry correlates of ineff ective esophageal motility. Am J Gastroenterol 2012;107:1647-54
14. Shaw MJ, Talley NJ, Beebe TJ et al. Initial validation of a diagnostic questionnaire for gastroesophageal refl ux disease. Am J Gastroenterol 2001;96:52-7
15. Sifrim D, Castell D, Dent J et al. Gastro-oesophageal refl ux monitoring: Review and consensus report on detection and defi nitions of acid, non-Acid, and gas refl ux. Gut 2004;53:1024-31
16. Weusten BL, Roelofs JM, Akkermans LM et al. The symptom-Association probability: An improved method for symptom analysis of 24-hour esophageal pH data. Gastroenterology 1994;1071:1741-5
17. Ghosh SK, Pandolfi no JE, Kwiatek MA et al. Oesophageal peristaltic transition zone defects: Real but few and far between. Neurogastroenterol Motil 2008;20:1283-90
18. Sloan S, Kahrilas PJ. Impairment of esophageal emptying with hiatal hernia. Gastroenterology 1991;100:596-605
19. Emerenziani S, Habib FI, Ribolsi M et al. Effect of hiatal hernia on proximal oesophageal acid clearance in gastro-oesophageal refl ux disease patients. Aliment Pharmacol Ther 2006;23:751-7
20. Mart í nek J, Benes M, Hucl T et al. Non-erosive and erosive gastroesophageal refl ux diseases: No diff erence with regard to refl ux pattern and motility abnormalities. Scand J Gastroenterol 2008;43:794-800
21. Lemme EM, Abrahão-Junior LJ, Manhães Y et al. Ineff ective esophageal motility in gastroesophageal erosive refl ux disease and in nonerosive refl ux disease: Are they diff erent? J Clin Gastroenterol 2005;39:224-7
22. Ouatu-Lascar R, Lin OS, Fitzgerald RC et al. Upright versus supine refl ux in gastroesophageal refl ux disease. J Gastroenterol Hepatol 2001;16:1184-90
23. Freidin N, Fisher MJ, Taylor W, et al. Sleep and nocturnal acid refl ux in normal subjects and patients with refl ux oesophagitis. Gut 1991;32:1275-9
24. Holloway RH. Esophageal body motor response to refl ux events: Secondary peristalsis. Am J Med 2000;108 (Suppl 4a):20S-6S.
25. Zhang X, Geboes K, Depoortere I et al. Effect of repeated cycles of acute esophagitis and healing on esophageal peristalsis, tone, and length. Am J Physiol Gastrointest Liver Physiol 2005;288:1339-46
26. Singh P, Adamopoulos A, Taylor RH et al. Oesophageal motor function before and aft er healing of oesophagitis. Gut 1992;33:1590-6
27. Williams D, Th ompson DG, Heggie L et al. Esophageal clearance function following treatment of esophagitis. Gastroenterology 1994;106:108-16