Prostaglandin D2 is crucial for seizure suppression and postictal sleep

Experimental Neurology

Volumn 253, Issue , 2014, Pages 82-90

  Kaushik, Mahesh K ^a,b   Aritake, Kosuke ^a,b   Kamauchi, Shinya ^b   Hayaishi, Osamu ^b   Huang, Zhi Li ^b,c   Lazarus, Michael ^a,b   Urade, Yoshihiro ^a,b  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b OSAKA BIOSCIENCE INSTITUTE   (Japan)

^c FUDAN UNIVERSITY   (China)

Author keywords

Convulsion; CRTH2 (DP2) receptor; Electrographic seizures; Postictal EEG depression; Prostaglandin E2; Prostaglandin F2 ; Prostanoid; REM sleep

Indexed keywords

6 OXOPROSTAGLANDIN F1 ALPHA; HEMATOPOIETIC PROSTAGLANDIN SYNTHASE; LIPOCALIN TYPE PROSTAGLANDIN SYNTHASE; PROSTACYCLIN; PROSTAGLANDIN D2; PROSTAGLANDIN DP1 RECEPTOR; PROSTAGLANDIN DP2 RECEPTOR; PROSTAGLANDIN E2; PROSTAGLANDIN F2 ALPHA; PROSTAGLANDIN RECEPTOR; PROSTAGLANDIN SYNTHASE; THROMBOXANE A2; THROMBOXANE B2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE COURSE; DISEASE DURATION; DISEASE SEVERITY; ELECTROENCEPHALOGRAM; KNOCKOUT MOUSE; LATENT PERIOD; MALE; MOLECULAR DYNAMICS; MOUSE; NERVOUS SYSTEM PARAMETERS; NEUROPATHOLOGY; NONHUMAN; NONREM SLEEP; PENTYLENETETRAZOLE-INDUCED SEIZURE; POSTICTAL SLEEP; PRIORITY JOURNAL; SEIZURE SPIKE; SEIZURE SUPPRESSION; SLEEP DISORDER; TONIC CLONIC SEIZURE; WILD TYPE;

CONVULSION; CRTH2 (DP(2)) RECEPTOR; ELECTROGRAPHIC SEIZURES; POSTICTAL EEG DEPRESSION; PROSTAGLANDIN E(2); PROSTAGLANDIN F(2)Α; PROSTANOID; REM SLEEP;

6-KETOPROSTAGLANDIN F1 ALPHA; ANALYSIS OF VARIANCE; ANIMALS; BRAIN; CONVULSANTS; DINOPROSTONE; DISEASE MODELS, ANIMAL; ELECTROENCEPHALOGRAPHY; ELECTROMYOGRAPHY; INTRAMOLECULAR OXIDOREDUCTASES; LIPOCALINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PENTYLENETETRAZOLE; RECEPTORS, THROMBOXANE A2, PROSTAGLANDIN H2; SEIZURES; SLEEP, REM; TIME FACTORS; TRANSCRIPTION FACTOR DP1;

EID: 84891947417     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2013.12.002     Document Type: Article

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