-
1
-
-
0017862148
-
DHT concentrations in human prostate cancer tissue
-
Geller J, Albert J, Loza D, Geller S, Stoeltzing W, et al. DHT concentrations in human prostate cancer tissue. J Clin Endocrinol Metab 1978; 46: 440-4.
-
(1978)
J Clin Endocrinol Metab
, vol.46
, pp. 440-444
-
-
Geller, J.1
Albert, J.2
Loza, D.3
Geller, S.4
Stoeltzing, W.5
-
2
-
-
0842311632
-
The androgen axis in recurrent prostate cancer
-
Mohler JL, Gregory CW, Ford OH, Kim D, Weaver CM, et al. The androgen axis in recurrent prostate cancer. Clin Cancer Res 2004; 10: 440-8.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 440-448
-
-
Mohler, J.L.1
Gregory, C.W.2
Ford, O.H.3
Kim, D.4
Weaver, C.M.5
-
3
-
-
34250331066
-
Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: Therapeutic implications for castration-resistant prostate cancer
-
Mostaghel EA, Page ST, Lin DW, Fazli L, Coleman IM, et al. Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: Therapeutic implications for castration-resistant prostate cancer. Cancer Res 2007; 67: 5033-41.
-
(2007)
Cancer Res
, vol.67
, pp. 5033-5041
-
-
Mostaghel, E.A.1
Page, S.T.2
Lin, D.W.3
Fazli, L.4
Coleman, I.M.5
-
4
-
-
49249119358
-
Maintenance of intratumoral androgens in metastatic prostate cancer: A mechanism for castration-resistant tumor growth
-
Montgomery RB, Mostaghel EA, Vessella R, Hess DL, Kalhorn TF, et al. Maintenance of intratumoral androgens in metastatic prostate cancer: A mechanism for castration-resistant tumor growth. Cancer Res 2008; 68: 4447-54.
-
(2008)
Cancer Res
, vol.68
, pp. 4447-4454
-
-
Montgomery, R.B.1
Mostaghel, E.A.2
Vessella, R.3
Hess, D.L.4
Kalhorn, T.F.5
-
5
-
-
51049098138
-
Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer
-
Locke JA, Guns ES, Lubik AA, Adomat HH, Hendy SC, et al. Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer. Cancer Res 2008; 68: 6407-15.
-
(2008)
Cancer Res
, vol.68
, pp. 6407-6415
-
-
Locke, J.A.1
Guns, E.S.2
Lubik, A.A.3
Adomat, H.H.4
Hendy, S.C.5
-
6
-
-
84883367616
-
A gain-of-function mutation in DHT synthesis in castration-resistant prostate cancer
-
Chang KH, Li R, Kuri B, Lotan Y, Roehrborn CG, et al. A gain-of-function mutation in DHT synthesis in castration-resistant prostate cancer. Cell 2013; 154: 1074-84.
-
(2013)
Cell
, vol.154
, pp. 1074-1084
-
-
Chang, K.H.1
Li, R.2
Kuri, B.3
Lotan, Y.4
Roehrborn, C.G.5
-
7
-
-
77954909020
-
3beta-hydroxysteroid dehydrogenase is a possible pharmacological target in the treatment of castration-resistant prostate cancer
-
Evaul K, Li R, Papari-Zareei M, Auchus RJ, SharifiN. 3beta-hydroxysteroid dehydrogenase is a possible pharmacological target in the treatment of castration-resistant prostate cancer. Endocrinology 2010; 151: 3514-20.
-
(2010)
Endocrinology
, vol.151
, pp. 3514-3520
-
-
Evaul, K.1
Li, R.2
Papari-Zareei, M.3
Auchus, R.J.4
Sharifi, N.5
-
8
-
-
79951665862
-
The molecular biology, biochemistry, and physiology of human steroidogenesis and its disorders
-
Miller WL, Auchus RJ. The molecular biology, biochemistry, and physiology of human steroidogenesis and its disorders. Endocr Rev 2011; 32: 81-151.
-
(2011)
Endocr Rev
, vol.32
, pp. 81-151
-
-
Miller, W.L.1
Auchus, R.J.2
-
9
-
-
79951838692
-
Activation of the androgen receptor by intratumoral bioconversion of androstanediol to dihydrotestosterone in prostate cancer
-
Mohler JL, Titus MA, Bai S, Kennerley BJ, Lih FB, et al. Activation of the androgen receptor by intratumoral bioconversion of androstanediol to dihydrotestosterone in prostate cancer. Cancer Res 2011; 71: 1486-96.
-
(2011)
Cancer Res
, vol.71
, pp. 1486-1496
-
-
Mohler, J.L.1
Titus, M.A.2
Bai, S.3
Kennerley, B.J.4
Lih, F.B.5
-
10
-
-
8244262043
-
Dehydroepiandrosterone activates mutant androgen receptors expressed in the androgen dependent human prostate cancer xenograft CWR22 and LNCaP cells
-
Tan JA, Sharief Y, Hamil KG, Gregory CW, Zang DY, et al. Dehydroepiandrosterone activates mutant androgen receptors expressed in the androgen dependent human prostate cancer xenograft CWR22 and LNCaP cells. Mol Endocrinol 1997; 11: 450-9.
-
(1997)
Mol Endocrinol
, vol.11
, pp. 450-459
-
-
Tan, J.A.1
Sharief, Y.2
Hamil, K.G.3
Gregory, C.W.4
Zang, D.Y.5
-
11
-
-
33646541668
-
Probing the functional link between androgen receptor coactivator and ligand binding sites in prostate cancer and androgen insensitivity
-
He B, Gampe RT, Hnat AT, Faggart JL, Minges JT, et al. Probing the functional link between androgen receptor coactivator and ligand binding sites in prostate cancer and androgen insensitivity. J Biol Chem 2006; 281: 6648-63.
-
(2006)
J Biol Chem
, vol.281
, pp. 6648-6663
-
-
He, B.1
Gampe, R.T.2
Hnat, A.T.3
Faggart, J.L.4
Minges, J.T.5
-
12
-
-
7444233759
-
The backdoor pathway to dihydrotestosterone
-
Auchus RJ. The backdoor pathway to dihydrotestosterone. Trends Endocrinol Metab 2004; 15: 432-8.
-
(2004)
Trends Endocrinol Metab
, vol.15
, pp. 432-438
-
-
Auchus, R.J.1
-
13
-
-
79957443342
-
Abiraterone and increased survival in metastatic prostate cancer
-
de Bono JS, Logothetis CJ, Molina A, Fizazi K, North S, et al. Abiraterone and increased survival in metastatic prostate cancer. N Engl J Med 2011; 364: 1995-2005.
-
(2011)
N Engl J Med
, vol.364
, pp. 1995-2005
-
-
De Bono, J.S.1
Logothetis, C.J.2
Molina, A.3
Fizazi, K.4
North, S.5
-
14
-
-
84863304593
-
Abiraterone inhibits 3β-hydroxysteroid dehydrogenase: A rationale for increasing drug exposure in castration-resistant prostate cancer
-
Li R, Evaul K, Sharma KK, Chang KH, Yoshimoto J, et al. Abiraterone inhibits 3β-hydroxysteroid dehydrogenase: A rationale for increasing drug exposure in castration-resistant prostate cancer. Clin Cancer Res 2012; 18: 3571-9.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 3571-3579
-
-
Li, R.1
Evaul, K.2
Sharma, K.K.3
Chang, K.H.4
Yoshimoto, J.5
-
15
-
-
76249096762
-
Evidence of limited contributions for intratumoral steroidogenesis in prostate cancer
-
Hofland J, van Weerden WM, Dits N F, Steenbergen J, van Leenders GJ, et al. Evidence of limited contributions for intratumoral steroidogenesis in prostate cancer. Cancer Res 2010; 70: 1256-64.
-
(2010)
Cancer Res
, vol.70
, pp. 1256-1264
-
-
Hofland, J.1
Van Weerden, W.M.2
Dits, N.F.3
Steenbergen, J.4
Van Leenders, G.J.5
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