HIV-1 replication fitness of HLA-B*57/58:01 CTL Escape variants is restored by the accumulation of compensatory mutations in Gag

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Gijsbers, Esther F ^a   Anton Feenstra, K ^b,c   Van Nuenen, Ad C ^a   Navis, Marjon ^a,d   Heringa, Jaap ^b,c   Schuitemaker, Hanneke ^a,e   Kootstra, Neeltje A ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b AMSTERDAM INSTITUTE FOR MOLECULES   (Netherlands)

^c NETHERLANDS BIOINFORMATICS CENTRE   (Netherlands)

^d KAROLINSKA INSTITUTE   (Sweden)

^e CRUCELL HOLLAND BV   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GAG PROTEIN; HLA B ANTIGEN; HLA-B57 ANTIGEN; HLA-B58;

AMINO ACID SEQUENCE; ARTICLE; CLINICAL ARTICLE; CYTOTOXIC T LYMPHOCYTE; DISEASE COURSE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; LONGITUDINAL STUDY; MUTATION; NONHUMAN; SEQUENCE HOMOLOGY; VIRUS REPLICATION; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; IMMUNOLOGY; KINETICS; METABOLISM; PHYSIOLOGY; PROTEIN CONFORMATION;

DISEASE PROGRESSION; GAG GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; HIV-1; HLA-B ANTIGENS; HUMANS; KINETICS; MODELS, MOLECULAR; MUTATION; PROTEIN CONFORMATION; T-LYMPHOCYTES, CYTOTOXIC; VIRUS REPLICATION;

EID: 84891921477     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0081235     Document Type: Article

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