Investigating thought disorder in schizophrenia: Evidence for pathological activation

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Safadi, Ziad ^a,b   Lichtenstein Vidne, Limor ^b   Dobrusin, Michael ^b   Henik, Avishai ^b  

^a UNIVERSITY OF ROCHESTER   (United States)

^b BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ACCURACY; ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; INHIBITION (PSYCHOLOGY); MALE; NERVOUS SYSTEM PARAMETERS; NEUROMODULATION; OUTCOME ASSESSMENT; RESPONSE TIME; SCHIZOPHRENIA; STIMULUS ONSET ASYNCHRONY; THOUGHT DISORDER;

ADULT; CASE-CONTROL STUDIES; FEMALE; HUMANS; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; REACTION TIME; SCHIZOPHRENIC PSYCHOLOGY; SEMANTICS; THINKING; YOUNG ADULT;

EID: 84891909662     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0082882     Document Type: Article

References (54)

1. Kiefer M, Martens U, Weisbrod M, Hermle L, Spitzer M (2009) Increased unconscious semantic activation in schizophrenia patients with formal thought disorder. Schizophr Res 114: 79-83. doi:10.1016/j.schres.2009.07.024. PubMed: 19716272.
2. Quelen F, Grainger J, Raymondet P (2005) An investigation of semantic priming in schizophrenia using a new priming paradigm. Schizophr Res 80: 173-183. doi:10.1016/j.schres.2005.07.020. PubMed: 16140505. (Pubitemid 41713643)
3. Salisbury DF (2008) Semantic activation and verbal working memory maintenance in Schizophrenic Thought Disorder: Insights from electrophysiology and lexical ambiguity. Clin EEG Neurosci 39: 103-107. doi:10.1177/ 155005940803900217. PubMed: 18450179. (Pubitemid 351644623)
4. Manschreck TC, Maher BA, Milavetz JJ, Ames D, Weisstein CC et al. (1988) Semantic priming in thought disordered schizophrenic patients. Schizophr Res 1: 61-66. doi:10.1016/0920-9964(88)90041-2. PubMed: 3154508.
5. Kerns JG, Berenbaum H (2002) Cognitive impairments associated with formal thought disorder in people with schizophrenia. J Abnorm Psychol, 111: 211-224. doi:10.1037/0021-843X.111.2.211. PubMed: 12003444. (Pubitemid 34441200)
6. McNamara TP (2005) Semantic priming: Perspectives from memory and word recognition. New York: Psychology Press.
7. Kiang M, Christensen BK, Kutas M, Zipursky RB (2012) Electrophysiological evidence for primary semantic memory functional organization deficits in schizophrenia. Psychiatry Res, 196: 171-180. doi:10.1016/j.psychres.2012.02.026. PubMed: 22460130.
8. Mathalon DH, Roach BJ, Ford JM (2010) Automatic semantic priming abnormalities in schizophrenia. Int J Psychophysiol, 75: 157-166. doi: 10.1016/j.ijpsycho.2009.12.003. PubMed: 19995582.
9. Wang K, Cheung EFC, Gong QY, Chan RCK (2011) Semantic processing disturbance in patients with schizophrenia: A meta-analysis of the N400 component. PLOS ONE, 6(10 ): e25435. doi:10.1371/journal.pone.0025435. PubMed: 22022395.
10. Han SD, Nestor PG, Hale-Spencer M, Cohen A, Niznikiewicz M et al. (2007) Functional neuroimaging of word priming in males with chronic schizophrenia. NeuroImage, 35: 273-282. doi:10.1016/j.neuroimage.2006.11.029. PubMed: 17215145. (Pubitemid 46240928)
11. Neely JH (1991) Semantic priming effects in visual word recognition: A selective review of current findings and theories. In D BesnerG Humphreys, Basic processes in reading: Visual word recognition. Hillsdale, NJ: Erlbaum. (pp. 264-336).
12. Posner MI, Snyder CRR (1975a) Attention and cognitive control. In RL Solso, Information processing and cognition: The Loyola. Symposium. (pp. 55-85). Hillsdale, NJ: Erlbaum.
13. Posner MI, Snyder CRR (1975b) Facilitation and inhibition in the processing of signals. In PMA RabbitS Dornic, Attention and performance V. New York: Academic Press. (pp. 669-682).
14. Neely JH (1977) Semantic priming and retrieval from lexical memory: roles of inhibitionless spreading activation and limited-capacity attention. J Exp Psychol Gen, 106: 224-226.
15. Posner MI (1978) Chronometric explorations of mind. Hillsdale, NJ: Lawrence Erlbaum.
16. Lecardeur L, Giffard B, Laisney M, Brazo P, Delamillieure P et al. (2007) Semantic hyperpriming in schizophrenic patients: Increased facilitation or impaired inhibition in semantic association processing? Schizophr Res 89: 243-250. doi:10.1016/j.schres.2006.08.025. PubMed: 17046203. (Pubitemid 44895584)
17. Pomarol-Clotet E, Oh TM, Laws KR, McKenna PJ (2008) Semantic priming in schizophrenia: systematic review and meta-analysis. Br J Psychiatry, 192: 92-97. doi:10.1192/bjp.bp.106.032102. PubMed: 18245021. (Pubitemid 351269641)
18. Moritz S, Ruff C, Wilke U, Andresen B, Krausz M et al. (2001) Reduced negative priming in schizophrenia: Effects of masking and critical stimulus duration. Schizophr Res 48: 291-299. doi:10.1016/S0920-9964(00)00056-6. PubMed: 11295381. (Pubitemid 32274323)
19. Spitzer M, Weisker I, Winter M, Maier S, Hermle L et al. (1994) Semantic and phonological priming in schizophrenia. J Abnorm Psychol, 103: 485-494. doi:10.1037/0021-843X.103.3.485. PubMed: 7930048. (Pubitemid 24242892)
20. Gouzoulis-Mayfrank E, Voss T, Mörth D, Thelen B, Spitzer M et al. (2003) Semantic hyperpriming in thought-disordered patients with schizophrenia: state or trait?-a longitudinal investigation. Schizophr Res 65: 65-73. doi:10.1016/S0920-9964(03)00066-5. PubMed: 14630299. Available online at: doi:10.1016/S0920-9964(03)00066-5 Available online at: PubMed: 14630299 (Pubitemid 37434013)
21. Lerner I, Bentin S, Shriki O (2012) Excessive attractor instability accounts for semantic priming in schizophrenia. PLOS ONE ,7(7): e40663. doi:10.1371/journal.pone.0040663. PubMed: 22844407.
22. Moritz S, Woodward TS, Kuppers D, Lausen A, Schickel M (2002) Increased automatic spreading of activation in thought disordered schizophrenic patients. Schizophr Res 59: 181-186.
23. Henik A, Nissimov E, Priel B, Umansky R (1995) Effects of cognitive load on semantic priming in schizophrenic patients. J Abnorm Psychol, 104: 576-584. doi:10.1037/0021-843X.104.4.576. PubMed: 8530759.
24. Kwapil TR, Hegley DC, Chapman LJ, Chapman JP (1990) Facilitation of word recognition by semantic priming in schizophrenia. J Abnorm Psychol, 99: 215-221. doi:10.1037/0021-843X.99.3.215. PubMed: 2212270. (Pubitemid 20274077)
25. Barch DM, Carter CS, Perlstein W, Baird J, Cohen JD et al. (1999) Increased Stroop facilitation effects in schizophrenia are not due to increased automatic spreading activation. Schizophr Res 39: 51-64. doi:10.1016/S0920- 9964(99)00025-0. PubMed: 10480667. (Pubitemid 30074207)
26. Barch DM, Cohen JD, Servan-Schreiber D, Steingard S, Steinhauer SS et al. (1996) Semantic priming in schizophrenia: An examination of spreading activation using word pronunciation and multiple SOAs. J Abnorm Psychol, 105: 592-601. doi:10.1037/0021-843X.105.4.592. PubMed: 8952192. (Pubitemid 26378696)
27. Blum NA, Freides D (1995) Investigating thought disorder in schizophrenia with the lexical decision task. Schizophr Res 16: 217-224. doi:10.1016/0920- 9964(94)00078-M. PubMed: 7488567.
28. Chapin K, McCown J, Vann L, Kenney D, Youssef I (1992) Activation and facilitation in the lexicon of schizophrenics. Schizophr Res 6: 251-255. doi:10.1016/0920-9964(92)90008-S. PubMed: 1571317.
29. Henik A, Priel B, Umansky R (1992) Attention and automaticity in semantic processing of schizophrenic patients. Neuropsy Neuropsy Be, 5: 161-169.
30. Vinogradov S, Ober BA, Shenaut GK (1992) Semantic priming of word pronunciation and lexical decision in schizophrenia. Schizophr Res 8: 171-181. doi:10.1016/0920-9964(92)90033-2. PubMed: 1457395.
31. Aloia MS, Gourovitch ML, Missar D, Pickar D, Weinberger DR et al. (1998) Cognitive substrates of thought disorder. II. Specifying a candidate cognitive mechanism. Am J Psychiatry, 155: 1677-1684. PubMed: 9842775. (Pubitemid 28547490)
32. Condray R, Steinhauer SR, Cohen JD, van Kammen DP, Kasparek A (1999) Modulation of language processing in schizophrenia: Effects of context and haloperidol on the event-related potential. Biol Psychiatry, 45: 1336-1355. doi:10.1016/S0006-3223(98)00317-5. PubMed: 10349041. (Pubitemid 29292511)
33. Ober BA, Vinogradov S, Shenaut GK (1997) Automatic versus controlled semantic priming in schizophrenia. Neuropsychology, 77: 506-513. PubMed: 9345694. (Pubitemid 27459757)
34. Kreher DA, Holcomb PJ, Goff D, Kuperberg GK (2008) Neural evidence for faster and further automatic spreading activation in Schizophrenic Thought. Disord - Schizophrenia Bull, 34: 473-482.
35. Spitzer M (1997) A cognitive neuroscience view of schizophrenic thought disorder. Schizophrenia Bull, 23: 29-50. doi:10.1093/schbul/23.1.29. (Pubitemid 27087905)
36. Frith CD (1981) Schizophrenia, an abnormality of consciousness? In Underwood, G. & Stevens, R. (Eds.), Aspects of consciousness (vol. 2, pp. 437-443). London: Academic Press.
37. Bullen JG, Hemsley DR (1987) Schizophrenia: A failure to control the contents of consciousness? British J Clin Psychol, 26: 25-33. doi: 10.1111/j.2044-8260.1987.tb00720.x. PubMed: 3828593. (Pubitemid 17012671)
38. Carter CS, Robertson LC, Nordahl TE (1992) Abnormal processing of irrelevant information in chronic schizophrenia: Selective enhancement of Stroop facilitation. Psychiatry Res, 41: 137-146. doi: 10.1016/0165-1781(92)90105-C. PubMed: 1574540.
39. Maher BA (1983) A tentative theory of schizophrenic utterance. In BA MaherWB Maher, Progress in experimental personality research: Vol. 12. Psychopathology. New York: Academic Press. (pp. 1-52).
40. Maher BA, Manschrek TC, Hoover TM, Weisstien CC (1987) Thought disorder and measured features of language in schizophrenia. In P HarveyE Walker, Positive and negative symptoms in psychosis: Description, research and future directions. Hillsdale, NJ: Erlbaum. (pp. 195-215).
41. Spitzer M, Braun U, Hermle L, Maier S (1993) Associative semantic network dysfunction in thought-disordered schizophrenic patients: direct evidence from indirect semantic priming. Biol Psychiatry, 34: 864-877. doi:10.1016/0006- 3223(93)90054-H. PubMed: 8110913. (Pubitemid 24021231)
42. Barch DM, Csernansky JG (2007) Abnormal parietal cortex activation during working memory in schizophrenia: Verbal phonological coding disturbances versus domain-general executive dysfunction. Am J Psychiatry, 164: 1090-1098. doi:10.1176/appi.ajp.164.7.1090. PubMed: 17606661. (Pubitemid 47121398)
43. American Psychiatric Association (1994) Diagnostic and statistical manual of mental disorders, (4th ed.). Washington, DC: American Psychiatric Association.
44. Overall G, Gorham D (1962) The Brief Psychiatric Rating Scale. Psychological Reports, 10: 799-812. doi:10.2466/pr0.1962.10.3.799.
45. Weisbrod M, Maier S, Harig S, Himmelsbach U, Spitzer M (1998) Lateralised semantic and indirect semantic priming effects in people with schizophrenia. Br J Psychiatry, 172: 142-146. doi:10.1192/bjp. 172.2.142. PubMed: 9519066. (Pubitemid 28097712)
46. Minzenberg MJ, Ober BA, Vinogradov S (2002) Semantic priming in schizophrenia: a review and synthesis. J Int Neuropsychol Soc, 8: 699-720. PubMed: 12164679.
47. Friedrich FJ, Henik A, Tzelgov J (1991) Automatic processes in lexical access and spreading activation. J Exp Psychol Hum Percept Perform, 17: 792-806. doi:10.1037/0096-1523.17.3.792. PubMed: 1834791.
48. Henik A, Dronkers NF, Knight RT, Osimani A (1993) Differential effects of semantic and identity priming in patients with left and right hemisphere lesions. J Cogn Neurosci, 5: 45-55. doi:10.1162/jocn. 1993.5.1.45. PubMed: 23972119. (Pubitemid 23053086)
49. Henik A, Tzelgov J, Friedrich FJ (1993) Dissociation of lexical and semantic aspects in word processing. Isr J Med Sci, 29: 598-604. PubMed: 8225949.
50. Carr TH, Dagenbach D (1990) Semantic priming and repetition priming from masked words: Evidence for a center-surround attentional mechanism in perceptual recognition. J Exp Psychol Learn Mem Cogn, 16: 341-350. doi:10.1037/0278-7393. 16.2.341. PubMed: 2137871.
51. Besner D, Smith MC, MacLeod CM (1990) Visual word recognition: A dissociation of lexical and semantic processing. J Exp Psychol Learn 16: 862-869. doi:10.1037/0278-7393.16.5.862.
52. Cohen JD, Servan-Schreiber D (1992) Context, cortex and dopamine: a connectionist approach to behavior and biology in schizophrenia. Psychol Rev, 99: 45-77. doi:10.1037/0033-295X.99.1.45. PubMed: 1546118.
53. Wang Y, Fujita I, Murayama Y (2000) Neuronal mechanisms of selectivity for object features revealed by blocking inhibition in inferotemporal cortex. Nat Neurosci, 3: 807-813. doi:10.1038/77712. PubMed: 10903574. (Pubitemid 30485706)
54. Semantic bias, homograph comprehension, and event-related potentials in schizophrenia. Clinical Neurophysiology DOI 10.1016/S1388-2457(02)00003-2, PII S1388245702000032