Smooth muscle specific disruption of the endothelin-A receptor in mice reduces arterial pressure, and vascular reactivity and affects vascular development

Life Sciences

Volumn 118, Issue 2, 2014, Pages 238-243

  Donato, Anthony J ^a,b   Lesniewski, Lisa A ^a,b   Stuart, Deborah ^b   Walker, Ashley E ^b   Henson, Grant ^b   Sorensen, Lise ^b   Li, Dean ^a,b   Kohan, Donald E ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Endothelin A receptor; Endothelin 1; Vascular smooth muscle

Indexed keywords

CRE RECOMBINASE; DNA; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; MESSENGER RNA; SMOOTH MUSCLE ACTIN; SALT INTAKE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; BLOOD VESSEL DIAMETER; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; DNA RECOMBINATION; EMBRYO; EMBRYO DEVELOPMENT; EXON; FEMORAL ARTERY; GENE EXPRESSION; GENOTYPE; LOXP SITE; MEAN ARTERIAL PRESSURE; MOUSE; NONHUMAN; PRESSOR RESPONSE; PROMOTER REGION; RECEPTOR GENE; VASCULAR SMOOTH MUSCLE; VASCULAR SMOOTH MUSCLE CELL; VASOCONSTRICTION; WEANING; ANIMAL; ANTIBODY SPECIFICITY; BODY WEIGHT; DEFICIENCY; GENE DELETION; GROWTH, DEVELOPMENT AND AGING; HEMODYNAMICS; HYPERTENSION; KNOCKOUT MOUSE; METABOLISM; ORGAN SIZE; PATHOPHYSIOLOGY; REPRODUCIBILITY; SALT INTAKE;

ANIMALS; ARTERIAL PRESSURE; BODY WEIGHT; GENE DELETION; HEMODYNAMICS; HYPERTENSION; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; ORGAN SIZE; ORGAN SPECIFICITY; RECEPTOR, ENDOTHELIN A; REPRODUCIBILITY OF RESULTS; SODIUM CHLORIDE, DIETARY; VASOCONSTRICTION;

EID: 84891898392     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2013.12.209     Document Type: Article

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