Effects of highly conserved major histocompatibility complex (MHC) extended haplotypes on iron and low CD8+ T lymphocyte phenotypes in HFE C282Y homozygous hemochromatosis patients from three geographically distant areas

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Costa, Mónica ^a   Cruz, Eugénia ^a,b   Barton, James C ^c   Thorstensen, Ketil ^d   Morais, Sandra ^e,f   Da Silva, Berta M ^e   Pinto, Jorge P ^a   Vieira, Cristina P ^a   Vieira, Jorge ^a   Acton, Ronald T ^c,g   Porto, Graça ^a,b,e  

^a UNIVERSITY OF PORTO   (Portugal)

^b HOSPITAL DE SANTO ANTÓNIO   (Portugal)

^c University of Alabama at Birmingham   (United States)

^d TRONDHEIM UNIVERSITY HOSPITAL   (Norway)

^e UNIVERSITY OF PORTO   (Portugal)

^f HOSPITAL PEDRO HISPANO   (Portugal)

^g University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IRON; FERRITIN; GENETIC MARKER; HFE PROTEIN, HUMAN; HLA ANTIGEN CLASS 1; MEMBRANE PROTEIN;

ADULT; ARTICLE; CD8+ T LYMPHOCYTE; CHROMOSOME; CONTROLLED STUDY; FEMALE; GENETIC CONSERVATION; GENETIC MARKER; GEOGRAPHY; HAPLOTYPE; HEMOCHROMATOSIS; HEREDITARY HEMOCHROMATOSIS; HOMOZYGOSITY; HUMAN; IMMUNOPHENOTYPING; IRON STORAGE; MAJOR CLINICAL STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; NORWAY; PHENOTYPE; PORTUGAL; PREDICTIVE VALUE; UNITED STATES; BLOOD; GENETIC ASSOCIATION; GENETICS; METABOLISM; SINGLE NUCLEOTIDE POLYMORPHISM;

ALABAMA; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; FERRITINS; GENETIC ASSOCIATION STUDIES; GENETIC MARKERS; GEOGRAPHY; HAPLOTYPES; HEMOCHROMATOSIS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; IRON; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MEMBRANE PROTEINS; NORWAY; POLYMORPHISM, SINGLE NUCLEOTIDE; PORTUGAL;

EID: 84891891855     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0079990     Document Type: Article

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