Cellular internalization of fibroblast growth factor-12 exerts radioprotective effects on intestinal radiation damage independently of FGFR signaling

International Journal of Radiation Oncology Biology Physics

Volumn 88, Issue 2, 2014, Pages 377-384

  Nakayama, Fumiaki ^a   Umeda, Sachiko ^a   Yasuda, Takeshi ^b   Fujita, Mayumi ^a   Asada, Masahiro ^c   Meineke, Viktor ^d   Imamura, Toru ^c   Imai, Takashi ^a  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^b NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^c NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^d UNIVERSITY OF ULM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID RESIDUES; ANTI-APOPTOTIC EFFECTS; CELL-PENETRATING PEPTIDE; CELLULAR INTERNALIZATION; FIBROBLAST GROWTH FACTOR; METHODS AND MATERIALS; RADIATION-INDUCED APOPTOSIS; TOTAL BODY IRRADIATION;

AMINO ACIDS; DRUG PRODUCTS; GROWTH KINETICS; IRRADIATION; PEPTIDES; RADIATION DAMAGE; RADIATION PROTECTION; RADIOTHERAPY; SIGNALING;

RADIATION;

BROXURIDINE; CASPASE 3; CELL PENETRATING PEPTIDE; CESIUM 137; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 1; FIBROBLAST GROWTH FACTOR 12B; FIBROBLAST GROWTH FACTOR RECEPTOR; HEPARIN; MITOGEN ACTIVATED PROTEIN KINASE 14; PROTEOHEPARAN SULFATE; RADIOPROTECTIVE AGENT; UNCLASSIFIED DRUG; VILLIN;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL REGENERATION; CELL SURVIVAL; CONTROLLED STUDY; CRYPT CELL; GAMMA RADIATION; IN VITRO STUDY; IN VIVO STUDY; INTERNALIZATION; INTESTINE CELL; INTESTINE CRYPT; INTESTINE EPITHELIUM CELL; INTESTINE INJURY; JEJUNUM; MALE; MITOGENESIS; MOUSE; NICK END LABELING; NONHUMAN; PRE B LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION DOSE; RADIATION EXPOSURE; RADIATION INDUCED INTESTINAL INJURY; RADIATION INJURY; RADIATION PROTECTION; RAT; SIGNAL TRANSDUCTION; WHOLE BODY RADIATION;

AMINO ACIDS; ANIMALS; CELL PROLIFERATION; FIBROBLAST GROWTH FACTORS; JEJUNUM; MALE; MICE; MICE, INBRED BALB C; RADIATION INJURIES, EXPERIMENTAL; RADIATION TOLERANCE; RECEPTORS, FIBROBLAST GROWTH FACTOR; REGENERATION; WHOLE-BODY IRRADIATION;

EID: 84891886441     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2013.10.035     Document Type: Article

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