Early engraftment and full-donor chimerism after single-cord blood plus third-party donor dual transplantation in patients with high-risk acute leukemia

Bone Marrow Transplantation

Volumn 49, Issue 1, 2014, Pages 145-147

  Sanchez Ortega I ^a,b   Arnan, M ^a,b   Patino B ^a,b   Herrero, M J ^c   Querol, S ^d   Duarte, R F ^a,b  

^a CATALAN INSTITUTE OF ONCOLOGY   (Spain)

^b BELLVITGE BIOMEDICAL RESEARCH INSTITUTE IDIBELL   (Spain)

^c Edifici Escoles   (Spain)

^d Banc de Sang i Teixits   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; CIPROFLOXACIN; CORTICOSTEROID; COTRIMOXAZOLE; FLUDARABINE; METHYLPREDNISOLONE; PENTAMIDINE; POSACONAZOLE; THYMOCYTE ANTIBODY;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADULT; ADVANCED CANCER; ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ANTIBIOTIC PROPHYLAXIS; ANTIVIRAL THERAPY; BACTEREMIA; CANCER STAGING; CELL COUNT; CHIMERA; CLINICAL ARTICLE; COMMUNITY ACQUIRED PNEUMONIA; CORD BLOOD STEM CELL TRANSPLANTATION; CYTOMEGALOVIRUS; DRUG MEGADOSE; ENGRAFTMENT; ENTEROCOCCUS FAECIUM; ESCHERICHIA COLI; FEMALE; GRAFT VERSUS HOST REACTION; HEMORRHAGIC CYSTITIS; HIGH RISK PATIENT; HLA MATCHING; HUMAN; INFECTION PREVENTION; INFLUENZA A (H1N1); LETTER; MALE; MYELOABLATIVE CONDITIONING; MYELODYSPLASTIC SYNDROME; OPPORTUNISTIC INFECTION; OUTCOME ASSESSMENT; PNEUMOCYSTIS JIROVECI; PNEUMOCYSTOSIS; POLYOMAVIRUS INFECTION; PRIORITY JOURNAL; STEROID THERAPY; STREPTOCOCCUS MITIS; SURVIVAL RATE; TREATMENT DURATION; TREATMENT RESPONSE; URINARY TRACT INFECTION; VIRUS REACTIVATION;

ADULT; COHORT STUDIES; CORD BLOOD STEM CELL TRANSPLANTATION; FEMALE; GRAFT VS HOST DISEASE; HUMANS; LEUKEMIA, MYELOID, ACUTE; MALE; MIDDLE AGED; MYELODYSPLASTIC SYNDROMES; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; RECURRENCE; TRANSPLANTATION CHIMERA; TRANSPLANTATION CONDITIONING; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84891884920     PISSN: 02683369     EISSN: 14765365     Source Type: Journal    
DOI: 10.1038/bmt.2013.113     Document Type: Letter

References (10)

1. Sanz MA. Cord-blood transplantation in patients with leukemia-a real alternative for adults. N Engl J Med 2004; 351: 2328-2330.
2. Rocha V, Gluckman E. Improving outcomes of cord blood transplantation: HLA matching, cell dose and other graft and transplantation related factors. Eurocord-Netcord registry and European Blood and Marrow Transplant Group. Br J Haematol 2009; 147: 262-274.
3. Fernandez MN. Improving the outcome of cord blood transplantation: use of mobilized HSC and other cells from third party donors. Review. Br J Haematol 2009; 147: 161-176.
4. Bacigalupo A, Ballen K, Rizzo D, Giralt S, Lazarus H, Ho V et al. Defining the intensity of conditioning regimens: working definitions. Biol Blood Marrow Transplant 2009; 15: 1628-1633.
5. Gluckman E, Rocha V. Donor selection for unrelated cord blood transplants. Curr Opin Immunol 2006; 18: 565-570.
6. Miller AN, Glode A, Hogan KR, Schaub C, Kramer C, Stuart RK et al. Efficacy and safety of ciprofloxacin for prophylaxis of polyoma BK virus-associated hemorrhagic cystitis in allogeneic hematopoietic stem cell transplantation recipients. Biol Blood Marrow Transplant 2011; 17: 1176-1181.
7. Kwon M, Balsalobre P, Serrano D, Perez Corral A, Buno I, Anguita J et al. Single cord blood combined with HLA-mismatched third party donor cells: comparable results to matched unrelated donor transplantation in high-risk patients with hematologic disorders. Biol Blood Marrow Transplant 2013; 19: 143-149.
8. Liu H, Rich ES, Godley L, Odenike O, Joseph L, Marino S et al. Reduced-intensity conditioning with combined haploidentical and cord blood transplantation results in rapid engraftment, low GVHD, and durable remissions. Blood 2011; 118: 6438-6445.
9. Childs RW. Combined cord blood and haploidentical CD34+ cell transplantation improves transplant outcome for patients with treatment-refractory severe aplastic anemia [abstract]. 10th International Cord Blood Symposium 36, 2012. Available at http://www.cordbloodsymposium.org/.
10. Lindemans CA, Kuball JHE, te Boome LCJ, Versluys AB, Bierings MB, Boelens JJ. Coinfusion of haploidentical donor stem cells with unrelated cord blood[abstract]. 10th International Cord Blood Symposium 5, 2012. Available at http://www.cordbloodsymposium.org/.