Improved survival endpoints with adjuvant radiation treatment in patients with high-risk early-stage endometrial carcinoma

International Journal of Radiation Oncology Biology Physics

Volumn 88, Issue 2, 2014, Pages 351-356

  Elshaikh, Mohamed A ^a   Vance, Sean ^a   Suri, Jaipreet S ^a   Mahan, Meredith ^a   Munkarah, Adnan ^a  

^a HENRY FORD HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMORADIATION THERAPIES; DISEASE-SPECIFIC SURVIVALS; ENDOMETRIAL CARCINOMAS; INDEPENDENT PREDICTORS; INTERNATIONAL FEDERATION; METHODS AND MATERIALS; MULTI VARIATE ANALYSIS; RECURRENCE-FREE SURVIVAL;

CHEMOTHERAPY; CYTOLOGY; GYNECOLOGY; HISTOLOGY; RADIOTHERAPY;

DIAGNOSIS;

ANTINEOPLASTIC AGENT; CARBOPLATIN; CISPLATIN; DOXORUBICIN; PACLITAXEL;

ABDOMINAL HYSTERECTOMY; ADJUVANT CHEMORADIOTHERAPY; ARTICLE; ASCITES FLUID CYTOLOGY; BRACHYTHERAPY; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURVIVAL; DISEASE SPECIFIC SURVIVAL; ENDOMETRIUM CARCINOMA; FEMALE; FOLLOW UP; HUMAN; LYMPH NODE DISSECTION; MAJOR CLINICAL STUDY; MEDICAL RECORD REVIEW; MULTIPLE CYCLE TREATMENT; OVERALL SURVIVAL; PRIORITY JOURNAL; RECURRENCE FREE SURVIVAL; RETROSPECTIVE STUDY; SALPINGOOOPHORECTOMY;

AGED; DISEASE-FREE SURVIVAL; ENDOMETRIAL NEOPLASMS; FEMALE; HUMANS; HYSTERECTOMY; NEOPLASM GRADING; NEOPLASM STAGING; OVARIECTOMY; RADIOTHERAPY, ADJUVANT; RETROSPECTIVE STUDIES;

EID: 84891879621     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2013.11.003     Document Type: Article

References (25)

1. R. Siegel, D. Naishadham, and A. Jemal Cancer statistics, 2013 CA Cancer J Clin 63 2013 11 30
2. Creasman WT, Odicino F, Maisonneuve P, et al. Carcinoma of the corpus uteri. FIGO 26th Annual Report on the Results of Treatment in Gynecological Cancer. http://www.ncbi.nlm.nih.gov/pubmed/17161155-# 2006; Suppl 1:S105-S143.
3. C.L. Creutzberg, W.L. van Putten, and P.C. Koper et al. Surgery and postoperative radiotherapy versus surgery alone for patients with stage-1 endometrial carcinoma: Multicentre randomised trial. PORTEC Study Group. Post Operative Radiation Therapy in Endometrial Carcinoma Lancet 355 2000 1404 1411 (Pubitemid 30215963)
4. H.M. Keys, J.A. Roberts, and V.L. Brunetto et al. A phase III trial of surgery with or without adjunctive external pelvic radiation therapy in intermediate risk endometrial adenocarcinoma: A Gynecologic Oncology Group study Gynecol Oncol 92 2004 744 751 (Pubitemid 38251372)
5. Gynecologic Oncology Group (GOG) study 0249 Protocol. Available at: https://www.ctsu.org/public/data/protocols/GOG/GOG-0249/schema.pdf. Accessed August 30, 2013.
6. S.G. Silverberg, G.L. Mutter, and R.J. Kurman et al. Tumors of the breast and female genital organs F.A. Tavassoli, P. Devilee, WHO Pathology and Genetics 2003 IARC Press Lyon 221 232
7. The ASTEC/EN 5 writing committee on behalf of the ASTEC/EN.5 Study Group: Adjuvant external beam radiotherapy in the treatment of endometrial cancer (MRC ASTEC and NCIC CTG EN.5 randomised trials): pooled trial results, systematic review, and meta-analysis Lancet 373 2009 137 146
8. R. Nout, V. Smit, and H. Putter et al. Vaginal brachytherapy versus pelvic external beam radiotherapy for patients with endometrial cancer of high-intermediate risk (PORTEC-2): An open-label, non-inferiority, randomised trial Lancet 375 2010 816 823
9. N. Johnson, and P. Cornes Survival and recurrent disease after postoperative radiotherapy for early endometrial cancer: Systematic review and meta-analysis BJOG 114 2007 1313 1320 (Pubitemid 47609926)
10. O.K. Macdonald, W.T. Sause, and R.J. Lee et al. Adjuvant radiotherapy and survival outcomes in early-stage endometrial cancer: A multi-institutional analysis of 608 women Gynecol Oncol 103 2006 661 666 (Pubitemid 44602184)
11. R. Yechieli, N. Rasool, and J.R. Robbins et al. Adjuvant radiation therapy for patients with type II endometrial carcinoma: Impact on tumor recurrence and survival Int J Gynecol Cancer 23 2013 763 768
12. A. Kim, D. Schreiber, and J. Rineer et al. Impact of adjuvant external-beam radiation therapy in early-stage uterine papillary serous and clear cell carcinoma Int J Radiat Oncol Biol Phys 81 2011 639 644
13. C.A. Hamilton, W.S. Liou, and K. Osann et al. Impact of adjuvant therapy on survival of patients with early-stage uterine papillary serous carcinoma Int J Radiat Oncol Biol Phys 63 2005 839 844 (Pubitemid 41400073)
14. E.C. Batchelor, J.M. Watkins, and W.T. Creasman et al. The role of radiotherapy in the management of resected uterine papillary serous and clear cell carcinoma Eur J Obstet Gynecol Reprod Biol 141 2008 163 168
15. J.M. Straughn, W.K. Huh, and J.W. Orr Jr. et al. Stage IC adenocarcinoma of the endometrium: Survival comparisons of surgically staged patients with and without adjuvant radiation therapy Gynecol Oncol 89 2003 295 300 (Pubitemid 36457879)
16. M.L. Berman Adjuvant radiotherapy following properly staged endometrial cancer: What role? Gynecol Oncol 92 2004 737 739 (Pubitemid 38251370)
17. Z. Nicholas, N. Hu, and J. Ying et al. Impact of comorbid conditions on survival in endometrial cancer Am J Clin Oncol 2012 Dec 13 [Epub ahead of print] http://dx.doi.org/10.1097/COC.0b013e318277d5f4
18. S.H. Olson, C.L. Atoria, and M.L. Cote et al. The impact of race and comorbidity on survival in endometrial cancer Cancer Epidemiol Biomarkers Prev 21 2012 753 760
19. K.K. Ward, N.R. Shah, and C.C. Saenz et al. Cardiovascular disease is the leading cause of death among endometrial cancer patients Gynecol Oncol 126 2012 176 179
20. A. Jhingran, T.W. Burke, and P.J. Eifel Definitive radiotherapy for patients with isolated vaginal recurrence of endometrial carcinoma after hysterectomy Int J Radiat Oncol Biol Phys 56 2003 1366 1372 (Pubitemid 36842889)
21. W.K. Huh, J.M. Straughn Jr., and A. Mariani et al. Salvage of isolated vaginal recurrences in women with surgical stage I endometrial cancer: A multiinstitutional experience Int J Gynecol Cancer 17 2007 886 889 (Pubitemid 47063322)
22. Gayar OH, Patel S, Schultz D, et al. The impact of tumor grade on survival endpoints and patterns of recurrence of 949 patients with early stage endometrioid carcinoma: A single institution study. Int J Gynecol Cancer 2013 Nov 20 [epub ahead of print]. http://dx.doi.org/10.1097/IGC.0000000000000018.
23. K.C. Long, Q. Zhou, and M.L. Hensley et al. Patterns of recurrence in 1988 FIGO stage IC endometrioid endometrial cancer Gynecol Oncol 125 2012 99 102
24. N. Rasool, A.N. Fader, and L. Seamon et al. Stage I, grade 3 endometrioid adenocarcinoma of the endometrium: An analysis of clinical outcomes and patterns of recurrence Gynecol Oncol 116 2010 10 14
25. Post Operative Radiation Therapy in Endometrial Carcinoma (PORTEC-3) study. Available at http://www.clinicalresearch.nl/portec3/ Accessed August 30, 2013.