Neuropeptides released from trigeminal neurons promote the stratification of human corneal epithelial cells

Investigative Ophthalmology and Visual Science

Volumn 55, Issue 1, 2013, Pages 125-133

  Ko, Ji Ae ^a   Mizuno, Yukari ^b   Ohki, Chihiro ^a   Chikama, Tai Ichiro ^a   Sonoda, Koh Hei ^b   Kiuchi, Yoshiaki ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

^b YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Corneal epithelium; N cadherin; Neuropeptides; Stratification; Trigeminal ganglion

Indexed keywords

EID: 84891879233     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.13-12642     Document Type: Article

References (40)

1. Lazarov NE. Comparative analysis of the chemical neuroanatomy of the mammalian trigeminal ganglion and mesencephalic trigeminal nucleus. Prog Neurobiol. 2002;66:19-59.
2. Muller LJ, Marfurt CF, Kruse F, Tervo TM. Corneal nerves: structure, contents and function. Exp Eye Res. 2003;76:521-542.
3. Muller LJ, Vrensen GF, Pels L, Cardozo BN, Willekens B. Architecture of human corneal nerves. Invest Ophthalmol Vis Sci. 1997;38:985-994.
4. Bee JA. The development and pattern of innervation of the avian cornea. Dev Biol. 1982;92:5-15.
5. Song B, Zhao M, Forrester J, McCaig C. Nerve regeneration and wound healing are stimulated and directed by an endogenous electrical field in vivo. J Cell Sci. 2004;117:4681-4690.
6. Paton L. The trigeminal and its ocular lesions. Br J Ophthalmol. 1926;10:300-342.
7. Francois J, Hoffmann G, Soleme J. La keratite neuroparalytique et sa frequence après les diffrentes neurotomies pour nevralgie essentielle du trijumeau. Neurochirurgia. 1966;9: 81-98.
8. Beuerman RW, Schimmelpfenning B. Sensory denervation of the rabbit cornea affects epithelial properties. Exp Neurol. 1980;69:196-201.
9. Ferrari G, Chauhan SK, Ueno H, et al. A novel mouse model for neurotrophic keratopathy: trigeminal nerve stereotactic electrolysis through the brain. Invest Ophthalmol Vis Sci. 2011;52: 2532-2539.
10. Baker KS, Anderson SC, Romanowski EG, Thoft RA, SundarRaj N. Trigeminal ganglion neurons affect corneal epithelial phenotype: influence on type VII collagen expression in vitro. Invest Ophthalmol Vis Sci. 1993;34:137-144.
11. Garcia-Hirschfeld J, Lopez-Briones LG, Belmonte C. Neurotrophic influences on corneal epithelial cells. Exp Eye Res. 1994;59:597-605.
12. Palkama A, Uusitalo H, Lehtosalo J. Innervation of the anterior segment of the eye: with special reference to functional aspects. In: Panula P, Paivarinta H, Soinila S, eds. Neurohistochemistry: Modern Methods and Applications. New York: Liss; 1986:587-615.
13. Unger WG, Terenghi G, Zhang SQ, Polak JM. Alteration in the histochemical presence of tyrosine hydroxylase-and CGRPimmunoreactivities in the eye following chronic sympathetic or sensory denervation. Curr Eye Res. 1988;7:761-769.
14. Tinsley PW, Fridland GH, Killmar JT, Desiderio DM. Purification, characterization and localization of neuropeptides in the cornea. Peptides. 1989;9:1373-1379.
15. Kessler JA, Bell WO, Black IB. Interactions between the sympathetic and sensory innervation of the iris. J Neurosci. 1983;3:1301-1307.
16. Lima L, Obregon F, Cubillos S, Fazzino F, Jaimes I. Taurine as a micronutrient in development and regeneration of the central nervous system. Nutr Neurosci. 2001;4:439-443.
17. McLaughlin BJ, Caldwell RB, Sasaki Y, Wood TO. Freezefracture quantitative comparison of rabbit corneal epithelial and endothelial membranes. Curr Eye Res. 1985;4:951-962.
18. Wang Y, Chen M, Wolosin JM. ZO-1 in corneal epithelium; stratal distribution and synthesis induction by outer cell removal. Exp Eye Res. 1993;57:283-292.
19. Sugrue SP, Zieske JD. ZO1 in corneal epithelium: association to the zonula occludens and adherens junctions. Exp Eye Res. 1997;64:11-20.
20. Hanna C, Bicknell DS, O'Brien JE. Cell turnover in the adult human eye. Arch Ophthalmol. 1961;65:695-698.
21. Ban Y, Dota A, Cooper LJ, et al. Tight junction-related protein expression and distribution in human corneal epithelium. Exp Eye Res. 2003;76:663-669.
22. Ko JA, Liu Y, Yanai R, Chikama T, Takezawa T, Nishida T. Upregulation of tight-junctional proteins in corneal epithelial cells by corneal fibroblasts in collagen vitrigel cultures. Invest Ophthalmol Vis Sci. 2008;49:113-119.
23. Ko JA, Morishige N, Yanai R, Nishida T. Up-regulation of semaphorin 3A in human corneal fibroblasts by epidermal growth factor released from cocultured human corneal epithelial cells. Biochem Biophys Res Commun. 2008;377: 104-108.
24. Ko JA, Yanai R, Morishige N, Takezawa T, Nishida T. Upregulation of connexin43 expression in corneal fibroblasts by corneal epithelial cells. Invest Ophthalmol Vis Sci. 2009;50: 2054-2060.
25. Ko JA, Yanai R, Nishida T. IGF-1 released by corneal epithelial cells induces up-regulation of N-cadherin in corneal fibroblasts. J Cell Physiol. 2009;221:254-261.
26. Ko JA, Akamatsu Y, Yanai R, Nishida T. Effects of semaphorin 3A overexpression in corneal fibroblasts on the expression of adherens-junction proteins in corneal epithelial cells. Biochem Biophys Res Commun. 2010;396:781-786.
27. Ko JA, Yanai R, Chikama T, Nishida T. Down-regulation of matrix metalloproteinase-2 in corneal fibroblasts by interleukin-1 receptor antagonist release from corneal epithelial cells. Invest Ophthalmol Vis Sci. 2010;51:6286-6293.
28. Ko JA, Chikama T, Sonoda KH, Kiuchi Y. Up-regulation of matrix metalloproteinase-1 and interleukin-6 expression in cocultures of corneal fibroblasts and neural cells. Biochem Biophys Res Commun. 2012;419:537-542.
29. Araki-Sasaki K, Ohasi Y, Sasabe T, et al. An SV40-immortalized human corneal epithelial cell line and its characterization. Invest Ophthalmol Vis Sci. 1995;36:614-621.
30. Wolosin JM, Budak MT, Akinci MA. Ocular surface epithelial and stem cell development. Int J Dev Biol. 2004;48:981-991.
31. Kim JB, Islam S, Kim YJ, et al. N-cadherin extracellular repeat 4 mediates epithelial to mesenchymal transition and increased motility. J Cell Biol. 2000;151:1193-1206.
32. Hatta K, Takagi S, Fujisawa H, Takeichi M. Spatial and temporal expression pattern of N-cadherin cell adhesion molecules correlated with morphogenetic processes of chicken embryos. Dev Biol. 1987;120:215-227.
33. Takeichi M. The cadherins: cell-cell adhesion molecules controlling animal morphogenesis. Development. 1988;102: 639-655.
34. Charrasse S, Meriane M, Comunale F, Blangy A, Gauthier-Rouviere C. N-cadherin-dependent cell-cell contact regulates Rho GTPases and β-catenin localization in mouse C2C12 myoblasts. J Cell Biol. 2002;158:953-965.
35. Kamei J, Toyofuku T, Hori M. Negative regulation of p21 by β-catenin/ TCF signaling: a novel mechanism by which cell adhesion molecules regulate cell proliferation. Biochem Biophys Res Commun. 2003;312:380-387.
36. Derycke LDM, Bracke ME. N-cadherin in the spotlight of cellcell adhesion, differentiation, embryogenesis, invasion and signaling. Int J Dev Biol. 2004;48:463-476.
37. Bonini S, Rama P, Olzi D, Lambiase A. Neurotrophic keratitis. Eye. 2003;17:989-995.
38. Dastjerdi MH, Dana R. Corneal nerve alterations in dry eyeassociated ocular surface disease. Int Ophthalmol Clin. 2009; 49:11-20.
39. Sigelman S, Dohlman CH, Friedenwald JS. Mitotic and wound healing activities in the rat corneal epithelium: influence of various hormones and endocrine glands. Arch Ophthalmol. 1954;52:751-757.
40. Sigelman S, Friedenwald JS. Mitotic and wound-healing activities of the corneal epithelium: effect of sensory denervation. Arch Ophthalmol. 1954;52:46-57.