The clinical relevance of minor paroxysmal nocturnal hemoglobinuria clones in refractory cytopenia of childhood: A prospective study by EWOG-MDS

Leukemia

Volumn 28, Issue 1, 2014, Pages 189-192

  Aalbers, A M ^a,b   Van Der Velden, V H J ^b   Yoshimi, A ^c   Fischer, A ^c   Noellke, P ^c   Zwaan, C M ^a   Baumann, I ^d   Beverloo, H B ^b   Dworzak, M ^e   Hasle, H ^f   Locatelli, F ^g   De Moerloose, B ^h   Gohring G ⁱ   Schmugge, M ^j   Stary, J ^k   Zecca, M ^l   Langerak, A W ^b   Van Dongen, J J M ^b   Pieters, R ^a   Niemeyer, C M ^c   Van Den Heuvel Eibrink, M M ^a   more..

^a SOPHIA CHILDREN S HOSPITAL   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF FREIBURG   (Germany)

^d Clinical Centre South West   (Germany)

^e MEDICAL UNIVERSITY OF VIENNA   (Austria)

^f AARHUS UNIVERSITY HOSPITAL   (Denmark)

^g UNIVERSITY OF PAVIA   (Italy)

^h GHENT UNIVERSITY HOSPITAL   (Belgium)

ⁱ HANNOVER MEDICAL SCHOOL   (Germany)

^j UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

^k UNIVERSITY HOSPITAL MOTOL   (Czech Republic)

^l FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN A; GLYCOSYLPHOSPHATIDYLINOSITOL; THYMOCYTE ANTIBODY;

APLASTIC ANEMIA; CHILDHOOD DISEASE; CYTOPENIA; DYSPLASIA; ERYTHROCYTE; EVENT FREE SURVIVAL; FLOW CYTOMETRY; FOLLOW UP; GRANULOCYTE; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; IMMUNE RESPONSE; IMMUNOSUPPRESSIVE TREATMENT; KARYOTYPE; LETTER; MULTICENTER STUDY (TOPIC); PAROXYSMAL NOCTURNAL HEMOGLOBINURIA; PRIORITY JOURNAL; PROSPECTIVE STUDY; REFRACTORY ANEMIA; THROMBOCYTE;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; FEMALE; HEMOGLOBINURIA, PAROXYSMAL; HUMANS; INFANT; MALE; PANCYTOPENIA; PROSPECTIVE STUDIES;

EID: 84891877865     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2013.195     Document Type: Letter

References (16)

1. Niemeyer CM, Baumann I. Classification of childhood aplastic anemia and myelodysplastic syndrome. Hematology Am Soc Hematol Educ Program 2011; 2011: 84-89.
2. Sloand EM, Wu CO, Greenberg P, Young N, Barrett J. Factors affecting response and survival in patients with myelodysplasia treated with immunosuppressive therapy. J Clin Oncol 2008; 26: 2505-2511.
3. Yoshimi A, Baumann I, Fuhrer M, Bergstrasser E, Gobel U, Sykora KW et al. Immunosuppressive therapy with anti-thymocyte globulin and cyclosporine A in selected children with hypoplastic refractory cytopenia. Haematologica 2007; 92: 397-400. (Pubitemid 350143550)
4. Dunn DE, Tanawattanacharoen P, Boccuni P, Nagakura S, Green SW, Kirby MR et al. Paroxysmal nocturnal hemoglobinuria cells in patients with bone marrow failure syndromes. Ann Intern Med 1999; 131: 401-408. (Pubitemid 29444429)
5. Maciejewski JP, Follmann D, Nakamura R, Saunthararajah Y, Rivera CE, Simonis T et al. Increased frequency of HLA-DR2 in patients with paroxysmal nocturnal hemoglobinuria and the PNH/aplastic anemia syndrome. Blood 2001; 98: 3513-3519.
6. Wang H, Chuhjo T, Yasue S, Omine M, Nakao S. Clinical significance of a minor population of paroxysmal nocturnal hemoglobinuria-type cells in bone marrow failure syndrome. Blood 2002; 100: 3897-3902. (Pubitemid 35396854)
7. Yoshida N, Yagasaki H, Takahashi Y, Yamamoto T, Liang J, Wang Y et al. Clinical impact of HLA-DR15, a minor population of paroxysmal nocturnal haemoglobinuria-type cells, and an aplastic anaemia-associated autoantibody in children with acquired aplastic anaemia. Br J Haematol 2008; 142: 427-435. (Pubitemid 351962169)
8. Sugimori C, Mochizuki K, Qi Z, Sugimori N, Ishiyama K, Kondo Y et al. Origin and fate of blood cells deficient in glycosylphosphatidylinositol- anchored protein among patients with bone marrow failure. Br J Haematol 2009; 147: 102-112.
9. Timeus F, Crescenzio N, Lorenzati A, Doria A, Foglia L, Pagliano S et al. Paroxysmal nocturnal haemoglobinuria clones in children with acquired aplastic anaemia: a prospective single centre study. Br J Haematol 2010; 150: 483-485.
10. Iwanaga M, Furukawa K, Amenomori T, Mori H, Nakamura H, Fuchigami K et al. Paroxysmal nocturnal haemoglobinuria clones in patients with myelodysplastic syndromes. Br J Haematol 1998; 102: 465-474. (Pubitemid 28346588)
11. Dingli D, Luzzatto L, Pacheco JM. Neutral evolution in paroxysmal nocturnal hemoglobinuria. Proc Natl Acad Sci USA 2008; 105: 18496-18500.
12. Parker C, Omine M, Richards S, Nishimura J, Bessler M, Ware R et al. Diagnosis and management of paroxysmal nocturnal hemoglobinuria. Blood 2005; 106: 3699-3709. (Pubitemid 41739003)
13. Scheinberg P, Nunez O, Weinstein B, Biancotto A, Wu CO, Young NS. Horse versus rabbit antithymocyte globulin in acquired aplastic anemia. N Engl J Med 2011; 365: 430-438.
14. Yoshimi A, Niemeyer CM, Fuhrer MM, Strahm B. Comparison of the efficacy of rabbit and horse antithymocyte globulin for the treatment of severe aplastic anemia in children. Blood 2013; 121: 860-861.
15. Araten DJ, Bessler M, McKenzie S, Castro-Malaspina H, Childs BH, Boulad F et al. Dynamics of hematopoiesis in paroxysmal nocturnal hemoglobinuria (PNH): no evidence for intrinsic growth advantage of PNH clones. Leukemia 2002; 16: 2243-2248. (Pubitemid 35331840)
16. Dallman PR, Siimes MA. Percentile curves for hemoglobin and red cell volume in infancy and childhood. The Journal of Pediatrics 1979; 94: 26-31. (Pubitemid 9036123)