Stimulation of adenosine Al receptor attenuates angiotensin II induced myocardial hypertrophy in neonatal rats via the extracellular signal-regulated kinase signal pathways

Chinese Journal of Cardiology

Volumn 41, Issue 8, 2013, Pages 698-703

  Li, Zhi Ye ^a   Yang, Yu Hong ^b   Xing, Ling ^a  

^a ZHENGZHOU UNIVERSITY   (China)

^b NONE

Author keywords

Adenosine; Angiotensin II; Cardiomyopathy, hypertrophic; Extracellular signal regulated MAP kinases

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; ADENOSINE A1 RECEPTOR; ADENOSINE A1 RECEPTOR AGONIST; ANGIOTENSIN II; ATRIAL NATRIURETIC FACTOR; CALCIUM ION; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; PERTUSSIS TOXIN; R PIA; UNCLASSIFIED DRUG; CALCIUM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EXPERIMENTAL CARDIAC HYPERTROPHY; FLUORESCENCE; HEART MUSCLE CELL; IN VITRO STUDY; NEWBORN; NONHUMAN; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; CARDIOMEGALY; CELL CULTURE; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; FEMALE; MALE; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT;

ADENOSINE A1 RECEPTOR AGONISTS; ANGIOTENSIN II; ANIMALS; CALCIUM; CARDIOMEGALY; CELLS, CULTURED; FEMALE; MALE; MAP KINASE SIGNALING SYSTEM; MYOCYTES, CARDIAC; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ADENOSINE A1;

EID: 84891856915     PISSN: 02533758     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0253-3758.2013.08.015     Document Type: Article

References (15)

1. Meyer T E, Chung E S, Perlini S, et al. Anliadrenergic effects of adenosine in pressure overload hypertrophy. Hypertension, 2001, 37: 862-868.
2. 2010, 26: 531-535.
3. 2+] i to adenosine A1- and A2 receptor stimulation in the isoproterenol-stimulated ventricular myocytes of spontaneously hypertensive rats. J Cardiovasc Pharmacol, 1998, 31: 493-498.
4. De Lander G E, Keil G J 2nd. Anlinociception induced hv intrathecal coadministration of selective adenosine receptor and selective opioid receptor agonists in mice. J Pharmacol Exp Ther, 1994, 268: 943-951.
5. Sadoshima J, Izumo S. The cellular and molecular response of cardie myocytes to mechanical stress. Annu Rev Physiol, 1997, 59: 551-571.
6. McCubrey J A, Steelman L S, Chappell W H, et al. Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance. Biochim Biophys Acta, 2007, 1773: 1263-1284.
7. 2008, 24: 307-312.
8. 2009, 3: 234-237.
9. 2010, 3: 180-184.
10. Kevelaitis E, Paynet J, Mouas C, et al. Opening of potassium channels: the common cardioprotective link between preconditioning and natural hibernation?. Circulation, 1999, 99: 3079-3085.
11. 2+ transport. Circ Res, 2003, 92: 769-776.
12. Lorell B H. Role of angiiotensin AT1, and AT2 receptors in cardiac hypertrophy and disease. Am J Cardiol, 1999, 83(12A): 48H-52H.
13. Mehta P K, Griendling K K. Angiotensin E cell signaling: physiological and pathological effects in the cardiovascular system. Am J Physiol Cell Physiol, 2007, 292: C82-C97.
14. Dubey R, Mi Z, Gillespie D G, et al. Dysregulation of extracellular adenosine levels by vascular smooth muscle cells from spontaneously hypertensive rats. Arterioscler Thromb Vase Biol, 2001, 21: 249-254.
15. 2+/calmodulin-dependent kinase II and calcineurin play critical roles in endothelin-1-induced cardiomyocyte hypertrophy. J Biol Chem, 2000, 275: 15239-15245.