Design and synthesis of potential dual NK1/NK3 receptor antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 2, 2014, Pages 510-514

  Hanessian, Stephen ^a   Babonneau, Vincent ^a   Boyer, Nicolas ^a   Mannoury La Cour, Clotilde ^b   Millan, Mark J ^b   De Nanteuil, Guillaume ^c  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

^c INSTITUT DE RECHERCHES SERVIER   (France)

Author keywords

Neurokinin receptors; NK1 NK 3 receptor antagonists; Peptidomimetic; Schizophrenia

Indexed keywords

AMIDE; NEUROKININ 1 RECEPTOR; NEUROKININ 1 RECEPTOR ANTAGONIST; NEUROKININ 3 RECEPTOR; NEUROKININ 3 RECEPTOR ANTAGONIST; PEPTIDOMIMETIC AGENT; PHENYLGLYCINE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG SYNTHESIS; HYDROGENOLYSIS; IN VITRO STUDY; NONHUMAN; RECEPTOR AFFINITY; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

NEUROKININ RECEPTORS; NK(1)/NK(3) RECEPTOR ANTAGONISTS; PEPTIDOMIMETIC; SCHIZOPHRENIA;

ANTIPSYCHOTIC AGENTS; DRUG DESIGN; NEUROKININ-1 RECEPTOR ANTAGONISTS; RECEPTORS, NEUROKININ-1; RECEPTORS, NEUROKININ-3; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84891855176     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.12.033     Document Type: Article

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