Dopamine transporter availability in heroin-dependent subjects and controls: Longitudinal changes during abstinence and the effects of Jitai tablets treatment

Psychopharmacology

Volumn 230, Issue 2, 2013, Pages 235-244

  Liu, Ying ^a,b   Han, Mei ^a   Liu, Xingdang ^b   Deng, Yanping ^c   Li, Yu ^d   Yuan, Jie ^b   Lv, Rongbin ^b   Wang, Yuankai ^b   Zhang, Guangming ^b   Gao, Jinlong ^a  

^a BEIJING NORMAL UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

^c PEKING UNIVERSITY   (China)

^d Drug Rehabilitation Center   (China)

Author keywords

Dopamine transporter; Heroin dependence; Jitai tablets; Single photon emission computed tomography

Indexed keywords

[2 [[2 [[[3 (4 CHLOROPHENYL) 8 METHYL 8 AZABICYCLO[3.2.1]OCT 2 YL]METHYL](2 MERCAPTOETHYL)AMINO]ETHYL]AMINO]ETHANETHIOLATO]OXOTECHNETIUM TC 99M; DOPAMINE TRANSPORTER; HERBACEOUS AGENT; JITAI TABLET; PLACEBO; UNCLASSIFIED DRUG;

ADULT; ANXIETY; ARTICLE; CAUDATE NUCLEUS; CONTROLLED STUDY; CORPUS STRIATUM; CROSSOVER PROCEDURE; DEPRESSION; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG WITHDRAWAL; FEMALE; HEROIN DEPENDENCE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PUTAMEN; RANDOMIZED CONTROLLED TRIAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

ADULT; ANXIETY; CASE-CONTROL STUDIES; CAUDATE NUCLEUS; CORPUS STRIATUM; DEPRESSION; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOUBLE-BLIND METHOD; DRUGS, CHINESE HERBAL; FEMALE; HEROIN DEPENDENCE; HUMANS; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; PUTAMEN; TABLETS; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 84891833332     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-013-3148-z     Document Type: Article

References (46)

1. Chang LT (1978) Method for attenuation correction in radionuclide computed tomography. IEEE Trans Nucl Sci 25:638-643
2. Chang JY, Zhang LL, Janak PH, Woodward DJ (1997) Neuronal responses in prefrontal cortex and nucleus accumbens during heroin self-administration in freely moving rats. Brain Res 754:12-20
3. Chen PS, Yang YK, Yeh TL, Lee IH, Yao WJ, Chiu NT, Lu RB (2008) Correlation between body mass index and striatal dopamine transporter availability in healthy volunteers - a SPECT study. Neuroimage 40:275-279
4. Chu H, Jin G, Friedman E, Zhen X (2008) Recent development in studies of tetrahydroprotoberberines: mechanism in antinociception and drug addiction. Cell Mol Neurobiol 28:491-499
5. 123I] β-CIT SPECT imaging study. Psychiatry Res 184:192-195
6. Di Chiara G, Imperato A (1988) Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc Natl Acad Sci USA 85:5274-5278
7. Felicio AC, Moriyama TS, Godeiro-Junior C, i Shih MC, Hoexter MQ, Borges V, Silva SMA, Amaro-Junior E, Andrate LAF, Ferraz HB, Bressan RA (2010) Higher dopamine transporter density in Parkinson's disease patients with depression. Psychopharmacology 211:27-31
8. Fleckenstein AE, Gibb JW, Hanson GR (2000) Differential effects of stimulants on monoaminergic transporters: pharmacological consequences and implications for neurotoxicity. Eur J Pharmacol 406:1-13
9. Gerra G, Zaimovic A, Zambelli U, Delsignore R, Baroni MC, Laviola G, Macchia T, Brambilla F (2000) Neuroendocrine correlates of depression in abstinent heroin-dependent subjects. Psychiatry Res 96:221-234
10. Gonzalez G, Oliveto A, Kosten TR (2002) Treatment of heroin (diamorphine) addiction - current approaches and future prospects. Drugs 62:1331-1343
11. Gupta GL, Rana AC (2008) Effect of Withania somnifera dunal in ethanol-induced anxiolysis and withdrawal anxiety in rats. Indian J Exp Biol 46:470-475
12. Hamilton M (1959) The assessment of anxiety-states by rating. Br J Med Psychol 32:50-55
13. Hamilton M (1960) A rating scale for depression. J Neurol Neurosurg Psychiatry 23:56-62
14. 99m Tc-TRODAT-1 imaging. J Nucl Med 42:1303-1308
15. TM capsule. Addict Biol 10:293-297
16. Kim HS, Kang JG, Oh KW (1995) Inhibition by ginseng total saponin of the development of morphine reverse tolerance and dopamine-receptor supersensitivity in mice. Gen Pharmacol 26:1071-1076
17. Kish SJ, Kalasinsky KS, Derkach P, Schmunk GA, Guttman M, Ang L, Adams V, Furukawa Y, Haycock JW (2001) Striatal dopaminergic and serotonergic markers in human heroin users. Neuropsychopharmacol 24:561-567
18. Kung HF, Kim HJ, Kung MP, Meegalla SK, Plossl K, Lee HK (1996) Imaging of dopamine transporters in humans with technetium-99m TRODAT-1. Eur J Nucl Med 23:1527-1530
19. Lee B, Kim H, Shim I, Lee H, Hahm D-H (2011) Wild ginseng attenuates anxiety- and depression-like behaviors during morphine withdrawal. J Microbiol Biotechnol 21:1088-1096
20. Li Z, Tang Y, Hua S, Wang Y (2007) Efficacy of Jitai for protracted withdrawal symptoms in heroin dependent patients. Chin J Drug Depend 16:284-287
21. Lu L, Liu Y, Zhu W, Shi J, Liu Y, Ling W, Kosten TR (2009) Traditional medicine in the treatment of drug addiction. Am J Drug Alcohol Abuse 35:1-11
22. 123I] β-CIT SPECT. Am J Psychiatry 155:832-834
23. 2 receptors and presynaptic dopamine in heroin dependence: commonalities and differences with other types of addiction. Biol Psychiatry 71:192-198
24. Mattioli L, Titomanlio F, Perfumi M (2012) Effects of a Rhodiola rosea L. extract on the acquisition, expression, extinction, and reinstatement of morphine-induced conditioned place preference in mice. Psychopharmacology 221:183-193
25. 11C]WIN-35,428. J Neurosci 18:8417-8422
26. McCann UD, Kuwabara H, Kumar A, Palermo M, Abbey R, Brasic J, Ye W, Alexander M, Dannals RF, Wong DF, Ricaurte GA (2008) Persistent cognitive and dopamine transporter deficits in abstinent methamphetamine users. Synapse 62:91-100
27. Nestler EJ (2005) Is there a common molecular pathway for addiction? Nat Neurosci 8:1445-1449
28. Shi J, Liu YL, Fang YX, Xu GZ, Zhai HF, Lu L (2006) Traditional Chinese medicine in treatment of opiate addiction. Acta Pharmacol Sin 27:1303-1308
29. Shi J, Zhao LY, Copersino ML, Fang YX, Chen Y, Tian A, Deng Y, Shuai Y, Jin J, Lu L (2008) PET imaging of dopamine transporter and drug craving during methadone maintenance treatment and after prolonged abstinence in heroin users. Eur J Pharmacol 579:160-166
30. Sklair-Tavron L, Shi WX, Lane SB, Harris HW, Bunney BS, Nestler EJ (1996) Chronic morphine induces visible changes in the morphology of mesolimbic dopamine neurons. Proc Natl Acad Sci USA 93:11202-11207
31. 2 receptor availability in vivo by regulating receptor affinity induced by facilitated synaptic dopamine turnover: positron emission tomography studies with microdialysis in the conscious monkey brain. J Neurosci 20:7067-7073
32. United Nations Office on Drug and Crime (2011) World drug report 2011. United Nations. http://www.unodc.org/unodc/en/data-and-analysis/WDR-2011.html. Accessed June 2011
33. Vandyck CH, Seibyl JP, Malison RT, Laruelle M, Wallace E, Zoghbi SS, Zeaponce Y, Baldwin RM, Charney DS, Hoffer PB, Innis RB (1995) Age-related decline in striatal dopamine transporter binding with iodine-123-β-CIT SPECT. J Nucl Med 36:1175-1181
34. Volkow ND, Chang L, Wang GJ, Fowler JS, Franceschi D, Sedler M, Gatley SJ, Miller E, Hitzemann R, Ding YS, Logan J (2001a) Loss of dopamine transporters in methamphetamine abusers recovers with protracted abstinence. J Neurosci 21:9414-9418
35. Volkow ND, Chang L, Wang GJ, Fowler JS, Leonido-Yee M, Franceschi D, Sedler MJ, Gatley SJ, Hitzemann R, Ding YS, Logan J, Wong C, Miller EN (2001b) Association of dopamine transporter reduction with psychomotor impairment in methamphetamine abusers. Am J Psychiatry 158:377-382
36. Volkow ND, Wang GJ, Telang F, Fowler JS, Logan J, Childress AR, Jayne M, Ma YM, Wong C (2006) Cocaine cues and dopamine in dorsal striatum: mechanism of craving in cocaine addiction. J Neurosci 26:6583-6588
37. Wang S, Liu L, Wang L, Jiang P, Zhang J, Zhang W, Liu R (2010) Screening and analysis of the multiple absorbed bioactive components and metabolites in rat plasma after oral administration of jitai tablets by high-performance liquid chromatography/diode-array detection coupled with electrospray ionization tandem mass spectrometry. Rapid Commun Mass Spectrom 24:1641-1652
38. Wang S, Liu L, Wang L, Hu Y, Zhang W, Liu R (2012) Structural characterization and identification of major constituents in Jitai tablets by high-performance liquid chromatography/diode-array detection coupled with electrospray ionization tandem mass spectrometry. Molecules 17:10470-10493
39. Wilson JM, Kalasinsky KS, Levey AI, Bergeron C, Reiber G, Anthony RM, Schmunk GA, Shannak K, Haycock JW, Kish SJ (1996) Striatal dopamine nerve terminal markers in human, chronic methamphetamine users. Nat Med 2:699-703
40. Wise RA, Leone P, Rivest R, Leeb K (1995) Elevations of nucleus-accumbens dopamine and DOPAC levels during intravenous heroin self-administration. Synapse 21:140-148
41. Xiang XH, Wang HL, Wu WR, Guo Y, Cao DY, Wang HS, Zhao Y (2006) Ethological analysis of scopolamine treatment or pretreatment in morphine dependent rats. Physiol Behav 88:183-190
42. Xiao ZW, Cao CY, Wang ZX, Li JX, Liao HY, Zhang XX (2006) Changes of dopamine transporter function in striatum during acute morphine addiction and its abstinence in rhesus monkey. Chin Med J 119:1802-1807
43. Xu G, Duan L, Wang Z, Liu R, Lu X, Wang Z, Tu Q, Sun G, Wang P, Cai Z (2000) A double-blind clinical trial of Jitai tablets vs Lofexidine in the treatment of heroin withdrawal symptoms. Chin J Drug Depend 9:273-277
44. Yang Z, Shao YC, Li SJ, Qi JL, Zhang MJ, Hao W, Jin GZ (2008) Medication of l-tetrahydropalmatine significantly ameliorates opiate craving and increases the abstinence rate in heroin users: a pilot study. Acta Pharmacol Sin 29:781-788
45. Yeh TL, Chen KC, Lin S-H, Lee IH, Chen PS, Yao WJ, Lee S-Y, Yang YK, Lu R-B, Liao M-H, Chiu N-T (2012) Availability of dopamine and serotonin transporters in opioid-dependent users - a two-isotope SPECT study. Psychopharmacology 220:55-64
46. 2 receptor binding and dopamine release during cue-elicited craving in recently abstinent opiate-dependent males. Eur Neuropsychopharmacol 18:262-270