Importance of epicardial adipose tissue thickness measurement in obese adolescents, its relationship with carotid intima-media thickness, and echocardiographic findings

European Review for Medical and Pharmacological Sciences

Volumn 17, Issue 24, 2013, Pages 3309-3317

  Boyraz, M ^a   Pirgon, Ozgur ^b   Akyol, B ^c   Dundar, B ^d   Cekmez, F ^e   Eren, N ^f  

^a FATIH UNIVERSITY   (Turkey)

^b SULEYMAN DEMIREL UNIVERSITY   (Turkey)

^c Bakirkoy   (Turkey)

^d IZMIR KATIP CELEBI UNIVERSITY   (Turkey)

^e GULHANE SCHOOL OF MEDICINE   (Turkey)

^f SISLI ETFAL TRAINING AND RESEARCH HOSPITAL   (Turkey)

Author keywords

Adolescent obesity; Atherosclerosis; Cardiac dysfunction; Carotid intima media thickness; Epicardial adipose tissue thickness

Indexed keywords

C REACTIVE PROTEIN; CHOLESTEROL; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADIPOSE TISSUE; ADOLESCENT; ADOLESCENT HEALTH; ADULT; ARTERIAL WALL THICKNESS; ARTICLE; BLOOD PRESSURE; BODY MASS; CARDIOVASCULAR RISK; CHILD; CHILDHOOD OBESITY; COMPARATIVE STUDY; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; ECHOCARDIOGRAPHY; EPICARDIAL ADIPOSE TISSUE THICKNESS; FEMALE; HEART LEFT VENTRICLE FUNCTION; HEART PERFORMANCE; HIP CIRCUMFERENCE; HUMAN; INSULIN SENSITIVITY; MAJOR CLINICAL STUDY; MALE; SCHOOL CHILD; SYSTOLIC BLOOD PRESSURE; TISSUE DOPPLER IMAGING;

ADIPOSE TISSUE; ADIPOSITY; ADOLESCENT; BODY MASS INDEX; CAROTID ARTERY DISEASES; CAROTID ARTERY, COMMON; CAROTID INTIMA-MEDIA THICKNESS; CASE-CONTROL STUDIES; CHILD; DIASTOLE; ECHOCARDIOGRAPHY, DOPPLER; FEMALE; HEART DISEASES; HUMANS; MALE; MULTIVARIATE ANALYSIS; PEDIATRIC OBESITY; PERICARDIUM; PREDICTIVE VALUE OF TESTS; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SYSTOLE; VENTRICULAR FUNCTION, LEFT;

EID: 84891822838     PISSN: 11283602     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. SIMONE G, DEVEREUX RB, WALLERSON DC. Echocardiographic assessment of left ventricular hypertrophy in rats using a simplified approach. Am J Hypertens 1994; 7: 555-558.
2. ECKEL RH, BAROUCH WW, ERSHOW AG. Report of the National Heart, Lung, and Blood Institute National Institute of Diabetes and Digestive and Kidney Diseases Working Group on the pathophysiology of obesity-associated cardiovascular disease. Circulation 2002; 105: 2923-2928.
3. FERNANDES VR, POLAK JF, EDVARDSEN T, CARVALHO B, GOMES A, BLUEMKE DA, NASIR K, O'LEARY DH, LIMA JA. Subclinical atherosclerosis and incipient regional myocardial dysfunction in asymptomatic individuals: the Multi-Ethnic Study of Atherosclerosis (MESA). J Am Coll Cardiol 2006; 47: 2420-2428.
4. POIRIER P, GILES TD, BRAY GA, HONG Y, STERN JS, PI-SUNYER FX, ECKEL RH; AMERICAN HEART ASSOCIATION; OBESITY COMMITTEE OF THE COUNCIL ON NUTRITION, PHYSICAL ACTIVITY, AND METABOLISM. Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss: an update of the 1997 American Heart Association Scientific Statement on Obesity and Heart Disease from the Obesity Committee of the Council on Nutrition, Physical Activity, and Metabolism. Circulation 2006; 113: 898-918.
5. IACOBELLIS G, RIBAUDO MC, ZAPPATERRENO A, IANNUCCI CV, DI MARIO U, LEONETTI F. Adapted changes in left ventricular structure and function in severe uncomplicated obesity. Obes Res 2004; 12: 1616-1621.
6. IACOBELLIS G, RIBAUDO MC, LETO G, ZAPPATERRENO A, VECCI E, DI MARIO U, LEONETTI F. Influence of excess fat on cardiac morphology and function: Study in uncomplicated obesity. Obes Res 2002; 10: 767-773.
7. SHIN J, LEE JU, KIM KS, KIM SG, KIM JH, LIM HK, LEE BH. Influence of abdominal circumference on the inappropriateness of left ventricular mass and diastolic function in non-obese patients. J Cardiol 2007; 49: 323-329.
8. MORRICONE L, MALAVAZOS AE, COMAN C, DONATI C, HASSAN T, CAVIEZEL F. Echocardiographic abnormalities in normotensive obese patients: Relationship with visceral fat. Obes Res 2002; 10: 489-498.
9. IACOBELLIS G, LEONETTI F, DI MARIO U. Images in cardiology: Massive epicardial adipose tissue indicating severe visceral obesity. Clin Cardiol 2003; 26: 237.
10. IACOBELLIS G, BIANCO AC. Epicardial adipose tissue: emerging physiological, pathophysiological and clinical features. Trends Endocrinol Metab 2011; 22: 450-457.
11. IACOBELLIS G, CORRADI D, SHARMA AM. Epicardial adipose tissue: anatomic, biomolecular and clinical relationships with the heart. Nat Clin Pract Cardiovasc Med 2005; 2: 536-543.
12. COLE TJ, BELLIZZI MC, FLEGAL KM, DIETZ WH. Establishing a standard definition for child overweight and obesity worldwide: international survey. Br Med J 2000; 320: 1240-1243.
13. SEN Y, KANDEMIR N, ALIKASIFOGLU A, GONC N, OZON A. Prevalence and risk factors of metabolic syndrome in obese children and adolescents: the role of the severity of obesity. Eur J Pediatr 2008; 167: 1183-1189.
14. HATIPOǦLU N, OZTURK A, MAZICIOGLU M, KURTOGLU S. Waist circumference percentiles for 7- to 17-yearold Turkish children and adolescents. Eur J Pediatr 2007; 167: 383-389.
15. NATIONAL HIGH BLOOD PRESSURE EDUCATION PROGRAM WORKING GROUP ON HIGH BLOOD PRESSURE IN CHILDREN AND ADOLESCENTS. The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics 2004; 114: 555-576.
16. CONWELL LS, TROST SG, BROWN WJ, BATCH JA. Indexes of insulin resistance and secretion in obese children and adolescents: a validation study. Diabetes Care 2004; 27: 314-319.
17. KESKIN M, KURTOGLU S, KENDIRCI M, ATABEK ME, YAZICI C. Homeostasis model assessment is more reliable than the fasting glucose/insulin ratio and quantitative insulin sensitivity check index for assessing insulin resistance among obese children and adolescents. Pediatrics 2005; 115: 500-503.
18. SAHN DJ, DEMARIA A, KISSLO J, WEYMAN A. Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements. Circulation 1978; 58: 1072-1083.
19. IACOBELLIS G, ASSAEL F, RIBAUDO MC, ZAPPATERRENO A, ALESSI G, DI MARIO U, LEONETTI F. Epicardial fat from echocardiography: a new method for visceral adipose tissue prediction. Obes Res 2003; 11: 304-310.
20. IACOBELLIS G, RIBAUDO MC, ASSAEL F, VECCI E, TIBERTI C, ZAPPATERRENO A, DI MARIO U, LEONETTI F. Echocardiographic epicardial adipose tissue is related to anthropometric and clinical parameters of metabolic syndrome: a new indicator of cardiovascular risk. J Clin Endocrinol Metab 2003; 88: 5163-5168.
21. TOUNIAN P, AGGOUN Y, DUBERN B, VARILLE V, GUYGRAND B, SIDI D, GIRARDET JP, BONNET D. Presence of increased stiffness of the common carotid artery and endothelial dysfunction in severely obese children: a prospective study. Lancet 2001; 358: 1400-1404.
22. TOUBOUL PJ, HENNERICI MG, MEAIRS S, ADAMS H, AMARENCO P, BORNSTEIN N, CSIBA L, DESVARIEUX M, EBRAHIM S, FATAR M, HERNANDEZ HERNANDEZ R, JAFF M, KOWNATOR S, PRATI P, RUNDEK T, SITZER M, SCHMINKE U, TARDIF JC, TAYLOR A, VICAUT E, WOO KS, ZANNAD F, ZUREIK M. Mannheim carotid intima-media thickness consensus (2004-2006). Cerebrovasc Dis 2007; 23: 75-80.
23. SCHEJBAL V. Epicardial fatty tissue of the right ventricle morphology, morphometry and functional significance. Pneumologie 1989; 43: 490-499.
24. OZDEMIR O, HIZLI S, ABACI A, AGLADIOGLU K, AKSOY S. Echocardiographic measurement of epicardial adipose tissue in obese children. Pediatr Cardiol 2010; 31: 853-860.
25. KARAYANNIS G, GIAMOUZIS G, TZIOLAS N, GEORGOULIAS P, SKOULARIGIS J, MIKHAILIDIS DP, TRIPOSKIADIS F. Association between epicardial fat thickness and weight homeostasis hormones in patients with noncachectic heart failure. Angiology 2013; 64: 173-180.
26. WHAYNE TF JR. Epicardial fat thickness in heart failure and other clinical conditions. Angiology 2013; 64: 169-172.
27. ABACI A, TASCILAR ME, SARITAS T, YOZGAT Y, YESILKAYA E, KILIC A, OKUTAN V, LENK MK. Threshold value of subepicardial adipose tissue to detect insulin resistance in obese children. Int J Obes (Lond) 2009; 33: 440-446.
28. CHARAKIDA M, TOUSOULIS D, STEFANADIS C. Early atherosclerosis in childhood: diagnostic approaches and therapeutic strategies. Int J Cardiol 2006; 109: 152-159.
29. DJABERI R, SCHUIJF JD, VAN WERKHOVEN JM, NUCIFORA G, JUKEMA JW, BAX JJ . Relation of epicardial adipose tissue to coronary atherosclerosis. Am J Cardiol 2008; 102: 1602-1607.
30. DE FEYTER PJ. Epicardial adipose tissue: an emerging role for the development of coronary atherosclerosis. Clin Cardiol 2011; 34: 143-144.
31. MUST A, JACQUES PF, DALLAL GE, BAJEMA CJ, DIETZ WH. Long-term morbidity and mortality of overweight adolescents: a follow-up of the Harvard Growth Study of 1922 to 1935. N Engl J Med 1992; 327: 1350-1355.
32. PETERSON LR, WAGGONER AD, DE LAS FUENTES L, SCHECHTMAN KB, MCGILL JB, GROPLER RJ, DÁVILA-ROMÁN VG. Alterations in left ventricular structure and function in young healthy obese women: assessment by echocardiography and tissue Doppler imaging. J Am Coll Cardiol 2004; 43: 1399-1404.
33. IPPISCH HM, INGE TH, DANIELS SR, WANG B, KHOURY PR, WITT SA, GLASCOCK BJ, GARCIA VF, KIMBALL TR. Reversibility of cardiac abnormalities in morbidly obese adolescents. J Am Coll Cardiol 2008; 51: 1342-1348.
34. KINIK ST, VARAN B, YILDIRIM SV, TOKEL K. The effect of obesity on echocardiographic and metabolic parameters in childhood. J Pediatr Endocrinol Metab 2006; 19: 1007-1014.
35. VAN PUTTE-KATIER N, ROOMAN RP, HAAS L, VERHULST SL, DESAGER KN, RAMET J, SUYS BE. Early cardiac abnormalities in obese children: importance of obesity per se versus associated cardiovascular risk factors. Pediatr Res 2008; 64: 205-209.
36. KONO Y, YOSHINAGA M, OKU S, NOMURA Y, NAKAMURA M, AISHOSHI S . Effect of obesity on echocardiographic parameters in children. Am J Cardiol 1994; 46: 7-13.
37. KAPUSTA L, THIJSSEN JM, CUYPERS MH, PEER PG, DANIELS O. Assessment of myocardial velocities in healthy children using tissue Doppler imaging. Ultrasound Med Biol 2000; 26: 229-237.
38. TEI C. New non-invasive index for combined systolic and diastolic ventricular function. J Cardiol 1995; 26: 135-136.
39. KHOSITSETH A, SUTHUTVORAVUT U, CHONGVIRIYAPHAN N, RUANGKANCHANASETR S . Cardiac dimensions and function in children with obesity. Indian Heart J 2007; 59: 142-146.
40. LEVENT E, GOKSEN D, OZYUREK AR, DARCAN S, COKER M. Usefulness of the myocardial performance index (MPI) for assessing ventricular function in obese pediatric patients. Turk J Pediatr 2005; 47: 34-38.