High-content screening assay for identification of chemicals impacting spontaneous activity in zebrafish embryos

Environmental Science and Technology

Volumn 48, Issue 1, 2014, Pages 804-810

  Raftery, Tara D ^a   Isales, Gregory M ^a   Yozzo, Krystle L ^a   Volz, David C ^a  

^a UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICALS; MAMMALS; OPTIMIZATION;

CELL-BASED ASSAYS; DEVELOPMENTAL NEUROTOXICITY; EMAMECTIN BENZOATE; HIGH-CONTENT SCREENING; POST-FERTILIZATION; SPONTANEOUS ACTIVITY; TRANSGENIC ZEBRAFISH; ZEBRAFISH EMBRYOS;

ASSAYS;

ABAMECTIN; AVERMECTIN; EMAMECTIN BENZOATE; UNCLASSIFIED DRUG; DISACCHARIDE; EMAMECTIN; IVERMECTIN; NEUROTOXIN; PARAOXON;

AUTOMATION; BENZENE; BIOASSAY; CHEMICAL REACTION; COST-BENEFIT ANALYSIS; EMBRYO; FISH; IMAGE ANALYSIS; LOCOMOTION; NEUROLOGY; OPTIMIZATION; POLLUTION EXPOSURE; RODENT; SENSORY SYSTEM; TOXICITY;

ADULT; ANIMAL EXPERIMENT; ARTICLE; CHEMICAL ANALYSIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; EMBRYO DEVELOPMENT; EXPOSURE; FEMALE; IMAGING; LOCOMOTION; MALE; NONHUMAN; SCREENING; ZEBRA FISH; ANALOGS AND DERIVATIVES; ANIMAL; ANIMAL EMBRYO; DRUG EFFECTS; EMBRYOLOGY; HIGH THROUGHPUT SCREENING; PHYSIOLOGY; PROCEDURES; REPRODUCIBILITY; TRANSGENIC ANIMAL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; DISACCHARIDES; EMBRYO, NONMAMMALIAN; HIGH-THROUGHPUT SCREENING ASSAYS; IVERMECTIN; NEUROTOXINS; PARAOXON; REPRODUCIBILITY OF RESULTS; ZEBRAFISH;

EID: 84891807493     PISSN: 0013936X     EISSN: 15205851     Source Type: Journal    
DOI: 10.1021/es404322p     Document Type: Article

References (34)

1. Grandjean, P.; Landrigan, P. J. Developmental neurotoxicity of industrial chemicals Lancet 2006, 368 (9553) 2167-2178
2. Giordano, G.; Costa, L. G. Developmental neurotoxicity: Some old and new issues ISRN Toxicol. 2012, 814795
3. Icenogle, L. M.; Christopher, N. C.; Blackwelder, W. P.; Caldwell, D. P.; Qiao, D.; Seidler, F. J.; Slotkin, T. A.; Levin, E. D. Behavioral alterations in adolescent and adult rats caused by a brief subtoxic exposure to chlorpyrifos during neurulation Neurotoxicol. Teratol. 2004, 26 (1) 95-101
4. Burbacher, T. M.; Rodier, P. M.; Weiss, B. Methylmercury developmental neurotoxicity: A comparison of effects in humans and animals Neurotoxicol. Teratol. 1990, 12 (3) 191-202
5. Burns, C. J.; McIntosh, L. J.; Mink, P. J.; Jurek, A. M.; Li, A. A. Pesticide exposure and neurodevelopmental outcomes: Review of the epidemiologic and animal studies J. Toxicol. Environ. Health B Crit. Rev. 2013, 16 (3-4) 127-283
6. Organization for Economic Co-operation and Development. OECD Guidelines for the Testing of Chemicals/Section 4: Health Effects. Test No. 426: Developmental Neurotoxicity Study; Paris, France, 2007.
7. Bjorling-Poulsen, M.; Andersen, H. R.; Grandjean, P. Potential developmental neurotoxicity of pesticides used in Europe Environ. Health 2008, 7, 50
8. Crofton, K. M.; Mundy, W. R.; Shafer, T. J. Developmental neurotoxicity testing: A path forward Congenit. Anom. (Kyoto) 2012, 52 (3) 140-146
9. Coecke, S.; Goldberg, A. M.; Allen, S.; Buzanska, L.; Calamandrei, G.; Crofton, K.; Hareng, L.; Hartung, T.; Knaut, H.; Honegger, P.; Jacobs, M.; Lein, P.; Li, A.; Mundy, W.; Owen, D.; Schneider, S.; Silbergeld, E.; Reum, T.; Trnovec, T.; Monnet-Tschudi, F.; Bal-Price, A. Workgroup report: Incorporating in vitro alternative methods for developmental neurotoxicity into international hazard and risk assessment strategies Environ. Health Perspect. 2007, 115 (6) 924-931
10. Crofton, K. M.; Mundy, W. R.; Lein, P. J.; Bal-Price, A.; Coecke, S.; Seiler, A. E.; Knaut, H.; Buzanska, L.; Goldberg, A. Developmental neurotoxicity testing: Recommendations for developing alternative methods for the screening and prioritization of chemicals ALTEX 2011, 28 (1) 9-15
11. Westerfield, M.; Liu, D. W.; Kimmel, C. B.; Walker, C. Pathfinding and synapse formation in a zebrafish mutant lacking functional acetylcholine receptors Neuron 1990, 4 (6) 867-874
12. Eisen, J. S.; Pike, S. H.; Debu, B. The growth cones of identified motoneurons in embryonic zebrafish select appropriate pathways in the absence of specific cellular interactions Neuron 1989, 2 (1) 1097-1104
13. Myers, P. Z.; Eisen, J. S.; Westerfield, M. Development and axonal outgrowth of identified motoneurons in the zebrafish J. Neurosci. 1986, 6 (8) 2278-2289
14. Westerfield, M.; McMurray, J. V.; Eisen, J. S. Identified motoneurons and their innervation of axial muscles in the zebrafish J. Neurosci. 1986, 6 (8) 2267-2277
15. Kokel, D.; Bryan, J.; Laggner, C.; White, R.; Cheung, C. Y. J.; Mateus, R.; Healey, D.; Kim, S.; Werdich, A. A.; Haggarty, S. J.; MacRae, C. A.; Shoichet, B.; Peterson, R. T. Rapid behavior-based identification of neuroactive small molecules in the zebrafish Nat. Chem. Biol. 2010, 6 (3) 231-237
16. Irons, T. D.; MacPhail, R. C.; Hunter, D. L.; Padilla, S. Acute neuroactive drug exposures alter locomotor activity in larval zebrafish Neurotoxicol. Teratol. 2010, 32 (1) 84-90
17. Stanley, K. A.; Curtis, L. R.; Simonich, S. L. M.; Tanguay, R. L. Endosulfan I and endosulfan sulfate disrupts zebrafish embryonic development Aquat. Toxicol. 2009, 95 (4) 355-361
18. Selderslaghs, I. W. T.; Hooyberghs, J.; Blust, R.; Witters, H. E. Assessment of the developmental neurotoxicity of compounds by measuring locomotor activity in zebrafish embryos and larvae Neurotoxicol. Teratol. 2013, 37, 44-56
19. Lawson, N. D.; Weinstein, B. M. In vivo imaging of embryonic vascular development using transgenic zebrafish Dev. Biol. 2002, 248 (2) 307-318
20. Kimmel, C. B.; Ballard, W. W.; Kimmel, S. R.; Ullmann, B.; Schilling, T. F. Stages of embryonic-development of the zebrafish Dev. Dyn. 1995, 203 (3) 253-310
21. NIH (National Institutes of Health). Guidelines for Use of Zebrafish in the NIH Intramural Research Program; Office of Animal Care and Use (OACU): Bethesda, MD, 2013; http://oacu.od.nih.gov/ARAC/documents/Zebrafish.pdf.
22. Yozzo, K. L.; McGee, S. P.; Volz, D. C. Adverse outcome pathways during zebrafish embryogenesis: A case study with paraoxon Aquat. Toxicol. 2013, 126, 346-354
23. Thomas, L. T.; Welsh, L.; Galvez, F.; Svoboda, K. R. Acute nicotine exposure and modulation of a spinal motor circuit in embryonic zebrafish Toxicol. Appl. Pharmacol. 2009, 239 (1) 1-12
24. Padilla, S.; Corum, D.; Padnos, B.; Hunter, D. L.; Beam, A.; Houck, K. A.; Sipes, N.; Kleinstreuer, N.; Knudsen, T.; Dix, D. J.; Reif, D. M. Zebrafish developmental screening of the ToxCast (TM) Phase I chemical library Reprod. Toxicol. 2012, 33 (2) 174-187
25. Downes, G. B.; Granato, M. Supraspinal input is dispensable to generate glycine-mediated locomotive behaviors in the zebrafish embryo J. Neurobiol. 2006, 66 (5) 437-451
26. Saint-Amant, L.; Drapeau, P. Time course of the development of motor behaviors in the zebrafish embryo J. Neurobiol. 1998, 37 (4) 622-632
27. Brustein, E.; Saint-Amant, L.; Buss, R.; Chong, M.; McDearmid, J.; Drapeau, P. Steps during the development of the zebrafish locomotor network J. Physiol.-Paris 2003, 97 (1) 77-86
28. Taylor, M. A. Recent developments in ectoparasiticides Vet. J. 2001, 161 (3) 253-268
29. Bloomquist, J. R. Ion channels as targets for insecticides Annu. Rev. Entomol. 1996, 41, 163-190
30. US EPA. Ecological Risk Assessment for Abamectin; Office of Prevention, Environmental Fate and Effects Division: Washington, D.C., 2004.
31. Sun, Y. J.; Long, D. X.; Li, W.; Hou, W. Y.; Wu, Y. J.; Shen, J. Z. Effects of avermectins on neurite outgrowth in differentiating mouse neuroblastoma N2a cells Toxicol. Lett. 2010, 192 (2) 206-211
32. Tisler, T.; Erzen, N. K. Abamectin in the aquatic environment Ecotoxicology 2006, 15 (6) 495-502
33. Wise, L. D.; Allen, H. L.; Hoe, C. M. L.; Verbeke, D. R.; Gerson, R. J. Developmental neurotoxicity evaluation of the avermectin pesticide, emamectin benzoate, in Sprague-Dawley rats Neurotoxicol. Teratol. 1997, 19 (4) 315-326
34. Padilla, S.; Hunter, D. L.; Padnos, B.; Frady, S.; MacPhail, R. C. Assessing locomotor activity in larval zebrafish: Influence of extrinsic and intrinsic variables Neurotoxicol. Teratol. 2011, 33 (6) 624-630