-
1
-
-
84891792977
-
-
International Diabetes Federation. Diabetes atlas [article online], Accessed 14 December 2012
-
International Diabetes Federation. Diabetes atlas [article online], 2011. Available from http://www.idf.org/diabetesatlas/5e/the-global-burden. Accessed 14 December 2012
-
(2011)
-
-
-
2
-
-
53749096863
-
10-year follow-up of intensive glucose control in type 2 diabetes
-
Holman RR, Paul SK, Bethel MA, Matthews DR, Neil HA. 10-year follow-up of intensive glucose control in type 2 diabetes. N Engl J Med 2008;359:1577-1589
-
(2008)
N Engl J Med
, vol.359
, pp. 1577-1589
-
-
Holman, R.R.1
Paul, S.K.2
Bethel, M.A.3
Matthews, D.R.4
Neil, H.A.5
-
3
-
-
38949210220
-
Effect of a multifactorial intervention on mortality in type 2 diabetes
-
Gaede P, Lund-Andersen H, Parving HH, Pedersen O. Effect of a multifactorial intervention on mortality in type 2 diabetes. N Engl J Med 2008;358:580-591
-
(2008)
N Engl J Med
, vol.358
, pp. 580-591
-
-
Gaede, P.1
Lund-Andersen, H.2
Parving, H.H.3
Pedersen, O.4
-
4
-
-
84891778825
-
-
U.S. Renal Data System. USRDS 2011 Annual Data Report: Atlas of Chronic Kidney Disease and End-Stage Renal Disease in the United States. Bethesda, MD, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases
-
U.S. Renal Data System. USRDS 2011 Annual Data Report: Atlas of Chronic Kidney Disease and End-Stage Renal Disease in the United States. Bethesda, MD, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, 2011
-
(2011)
-
-
-
5
-
-
84866268783
-
Management of hyper-glycemia in type 2 diabetes: A patient-centered approach: Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
-
American Diabetes Association (ADA); European Association for the Study of Diabetes (EASD).
-
Inzucchi SE, Bergenstal RM, Buse JB, et al.; American Diabetes Association (ADA); European Association for the Study of Diabetes (EASD). Management of hyper-glycemia in type 2 diabetes: a patient-centered approach: position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care 2012;35:1364-1379
-
(2012)
Diabetes Care
, vol.35
, pp. 1364-1379
-
-
Inzucchi, S.E.1
Bergenstal, R.M.2
Buse, J.B.3
-
6
-
-
84862302997
-
Ex-enatide twice daily versus glimepiride for prevention of glycaemic deterioration in patients with type 2 diabetes with met-formin failure (EUREXA): An open-label, randomised controlled trial
-
Gallwitz B, Guzman J, Dotta F, et al. Ex-enatide twice daily versus glimepiride for prevention of glycaemic deterioration in patients with type 2 diabetes with met-formin failure (EUREXA): an open-label, randomised controlled trial. Lancet 2012; 379:2270-2278
-
(2012)
Lancet
, vol.379
, pp. 2270-2278
-
-
Gallwitz, B.1
Guzman, J.2
Dotta, F.3
-
7
-
-
84864270406
-
Basal insulin and cardiovascular and other outcomes in dys-glycemia
-
ORIGIN Trial Investigators.
-
Gerstein HC, Bosch J, Dagenais GR, et al.; ORIGIN Trial Investigators. Basal insulin and cardiovascular and other outcomes in dys-glycemia. N Engl J Med 2012;367:319-328
-
(2012)
N Engl J Med
, vol.367
, pp. 319-328
-
-
Gerstein, H.C.1
Bosch, J.2
Dagenais, G.R.3
-
8
-
-
84862152967
-
Efficacy of GLP-1 receptor agonists and DPP-4 inhibitors: Meta-analysis and systematic review
-
Aroda VR, Henry RR, Han J, et al. Efficacy of GLP-1 receptor agonists and DPP-4 inhibitors: meta-analysis and systematic review. Clin Ther 2012;34:1247-1258
-
(2012)
Clin Ther
, vol.34
, pp. 1247-1258
-
-
Aroda, V.R.1
Henry, R.R.2
Han, J.3
-
9
-
-
80052645534
-
Glucagon-like peptide-1 analogues for type 2 diabetes mellitus: Current and emerging agents
-
Gallwitz B. Glucagon-like peptide-1 analogues for type 2 diabetes mellitus: current and emerging agents. Drugs 2011;71: 1675-1688
-
(2011)
Drugs
, vol.71
, pp. 1675-1688
-
-
Gallwitz, B.1
-
10
-
-
75649136250
-
Benefit-risk assessment of ex-enatide in the therapy of type 2 diabetes mellitus
-
Gallwitz B. Benefit-risk assessment of ex-enatide in the therapy of type 2 diabetes mellitus. Drug Saf 2010;33:87-100
-
(2010)
Drug Saf
, vol.33
, pp. 87-100
-
-
Gallwitz, B.1
-
11
-
-
84858139421
-
Liraglutide in oral antidiabetic drug combination therapy
-
Garber AJ. Liraglutide in oral antidiabetic drug combination therapy. Diabetes Obes Metab 2012;14(Suppl. 2):13-19
-
(2012)
Diabetes Obes Metab
, vol.14
, Issue.SUPPL. 2
, pp. 13-19
-
-
Garber, A.J.1
-
12
-
-
79953040963
-
An overview of once-weekly glucagon-like peptide-1 receptor agonistsdavailable efficacy and safety data and perspectives for the future
-
Madsbad S, Kielgast U, Asmar M, Deacon CF, Torekov SS, Holst JJ. An overview of once-weekly glucagon-like peptide-1 receptor agonistsdavailable efficacy and safety data and perspectives for the future. Diabetes Obes Metab 2011;13:394-407
-
(2011)
Diabetes Obes Metab
, vol.13
, pp. 394-407
-
-
Madsbad, S.1
Kielgast, U.2
Asmar, M.3
Deacon, C.F.4
Torekov, S.S.5
Holst, J.J.6
-
13
-
-
38549162147
-
Exenatide effects on diabetes, obesity, cardiovascular risk factors and hepatic biomarkers in patients with type 2 diabetes treated for at least 3 years
-
Klonoff DC, Buse JB, Nielsen LL, et al. Exenatide effects on diabetes, obesity, cardiovascular risk factors and hepatic biomarkers in patients with type 2 diabetes treated for at least 3 years. Curr Med Res Opin 2008;24:275-286
-
(2008)
Curr Med Res Opin
, vol.24
, pp. 275-286
-
-
Klonoff, D.C.1
Buse, J.B.2
Nielsen, L.L.3
-
14
-
-
67649666737
-
Liraglutide once a day versus exenatide twice a day for type 2 diabetes: A 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6)
-
LEAD-6 Study Group.
-
Buse JB, Rosenstock J, Sesti G, et al.; LEAD-6 Study Group. Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6). Lancet 2009;374:39-47
-
(2009)
Lancet
, vol.374
, pp. 39-47
-
-
Buse, J.B.1
Rosenstock, J.2
Sesti, G.3
-
15
-
-
84859003663
-
Effects of glucagon-like peptide-1 receptor agonists on weight loss: Systematic review and meta-analyses of randomised controlled trials
-
Vilsbøll T, Christensen M, Junker AE, Knop FK, Gluud LL. Effects of glucagon-like peptide-1 receptor agonists on weight loss: systematic review and meta-analyses of randomised controlled trials. BMJ 2012;344:d7771
-
(2012)
BMJ
, vol.344
-
-
Vilsbøll, T.1
Christensen, M.2
Junker, A.E.3
Knop, F.K.4
Gluud, L.L.5
-
16
-
-
26944477362
-
Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes: A randomized trial
-
GWAA Study Group
-
Heine RJ, Van Gaal LF, Johns D, Mihm MJ, Widel MH, Brodows RG; GWAA Study Group. Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes: a randomized trial. Ann Intern Med 2005;143:559-569
-
(2005)
Ann Intern Med
, vol.143
, pp. 559-569
-
-
Heine, R.J.1
Van Gaal, L.F.2
Johns, D.3
Mihm, M.J.4
Widel, M.H.5
Brodows, R.G.6
-
17
-
-
34247195226
-
A comparison of twice-daily exenatide and biphasic insulin aspart in patients with type 2 diabetes who were suboptimally controlled with sulfonylurea and metfor-min: A non-inferiority study
-
Nauck MA, Duran S, Kim D, et al. A comparison of twice-daily exenatide and biphasic insulin aspart in patients with type 2 diabetes who were suboptimally controlled with sulfonylurea and metfor-min: a non-inferiority study. Diabetologia 2007;50:259-267
-
(2007)
Diabetologia
, vol.50
, pp. 259-267
-
-
Nauck, M.A.1
Duran, S.2
Kim, D.3
-
18
-
-
37349008890
-
Tol-erability and efficacy of exenatide and titrated insulin glargine in adult patients with type 2 diabetes previously uncontrolled with metformin or a sulfonylurea: A multinational, randomized, open-label, two-period, crossover noninferiority trial
-
Barnett AH, Burger J, Johns D, et al. Tol-erability and efficacy of exenatide and titrated insulin glargine in adult patients with type 2 diabetes previously uncontrolled with metformin or a sulfonylurea: a multinational, randomized, open-label, two-period, crossover noninferiority trial. Clin Ther 2007;29:2333-2348
-
(2007)
Clin Ther
, vol.29
, pp. 2333-2348
-
-
Barnett, A.H.1
Burger, J.2
Johns, D.3
-
19
-
-
64249143715
-
Efficacy and safety of biphasic insulin aspart 70/30 versus exenatide in subjects with type 2 diabetes failing to achieve glycemic control with metformin and a sulfonylurea
-
NovoLog Mix-vs.-Exenatide Study Group.
-
Bergenstal R, Lewin A, Bailey T, Chang D, Gylvin T, Roberts V; NovoLog Mix-vs.-Exenatide Study Group. Efficacy and safety of biphasic insulin aspart 70/30 versus exenatide in subjects with type 2 diabetes failing to achieve glycemic control with metformin and a sulfonylurea. Curr Med Res Opin 2009;25:65-75
-
(2009)
Curr Med Res Opin
, vol.25
, pp. 65-75
-
-
Bergenstal, R.1
Lewin, A.2
Bailey, T.3
Chang, D.4
Gylvin, T.5
Roberts, V.6
-
20
-
-
79956151964
-
Exenatide twice daily versus premixed insulin aspart 70/30 in metformin-treated patients with type 2 diabetes: A randomized 26-week study on glycemic control and hypoglycemia
-
Gallwitz B, Böhmer M, Segiet T, et al. Exenatide twice daily versus premixed insulin aspart 70/30 in metformin-treated patients with type 2 diabetes: a randomized 26-week study on glycemic control and hypoglycemia. Diabetes Care 2011; 34:604-606
-
(2011)
Diabetes Care
, vol.34
, pp. 604-606
-
-
Gallwitz, B.1
Böhmer, M.2
Segiet, T.3
-
21
-
-
80054090833
-
Effects of exenatide on measures of b-cell function after 3 years in metformin-treated patients with type 2 diabetes
-
Bunck MC, Cornér A, Eliasson B, et al. Effects of exenatide on measures of b-cell function after 3 years in metformin-treated patients with type 2 diabetes. Diabetes Care 2011;34:2041-2047
-
(2011)
Diabetes Care
, vol.34
, pp. 2041-2047
-
-
Bunck, M.C.1
Cornér, A.2
Eliasson, B.3
-
22
-
-
84860618430
-
Safety and efficacy of once-weekly ex-enatide compared with insulin glargine titrated to target in patients with type 2 diabetes over 84 weeks
-
Diamant M, Van Gaal L, Stranks S, et al. Safety and efficacy of once-weekly ex-enatide compared with insulin glargine titrated to target in patients with type 2 diabetes over 84 weeks. Diabetes Care 2012;35:683-689
-
(2012)
Diabetes Care
, vol.35
, pp. 683-689
-
-
Diamant, M.1
Van Gaal, L.2
Stranks, S.3
-
23
-
-
69949117621
-
Liraglu-tide vs insulin glargine and placebo in combination with metformin and sulfo-nylurea therapy in type 2 diabetes mellitus (LEAD-5 met+SU): A randomised controlled trial
-
Liraglutide Effect and Action in Diabetes 5 (LEAD-5) met+SU Study Group.
-
Russell-Jones D, Vaag A, Schmitz O, et al.; Liraglutide Effect and Action in Diabetes 5 (LEAD-5) met+SU Study Group. Liraglu-tide vs insulin glargine and placebo in combination with metformin and sulfo-nylurea therapy in type 2 diabetes mellitus (LEAD-5 met+SU): a randomised controlled trial. Diabetologia 2009;52:2046-2055
-
(2009)
Diabetologia
, vol.52
, pp. 2046-2055
-
-
Russell-Jones, D.1
Vaag, A.2
Schmitz, O.3
-
24
-
-
80053401330
-
Glucagon-like peptide-1 receptor agonists versus insulin in inadequately controlled patients with type 2 diabetes mellitus: A meta-analysis of clinical trials
-
Wang Y, Li L, Yang M, Liu H, Boden G, Yang G. Glucagon-like peptide-1 receptor agonists versus insulin in inadequately controlled patients with type 2 diabetes mellitus: a meta-analysis of clinical trials. Diabetes Obes Metab 2011;13: 972-981
-
(2011)
Diabetes Obes Metab
, vol.13
, pp. 972-981
-
-
Wang, Y.1
Li, L.2
Yang, M.3
Liu, H.4
Boden, G.5
Yang, G.6
-
25
-
-
84891803789
-
-
Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results-A Long Term Evaluation (LEADER) [article online], Accessed 17 June 2012
-
Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results-A Long Term Evaluation (LEADER) [article online], 2012. Available from http://clinicaltrials.gov/ct2/show/NCT01179048. Accessed 17 June 2012
-
(2012)
-
-
-
26
-
-
84891775290
-
-
Exenatide Study of Cardiovascular Event Lowering Trial (EXSCEL): a trial to evaluate cardiovascular outcomes after treatment with exenatide once weekly in patients with type 2 diabetes mellitus [article online], Accessed 17 June 2012
-
Exenatide Study of Cardiovascular Event Lowering Trial (EXSCEL): a trial to evaluate cardiovascular outcomes after treatment with exenatide once weekly in patients with type 2 diabetes mellitus [article online]. Available from http://www.clinicaltrials.gov/ct2/show/NCT01144338. Accessed 17 June 2012
-
-
-
-
27
-
-
60449089649
-
Medical management of hyperglycemia in type 2 diabetes: A consensus algorithm for the initiation and adjustment of therapy: A consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes
-
American Diabetes Association; European Association for Study of Diabetes
-
Nathan DM, Buse JB, Davidson MB, et al.; American Diabetes Association; European Association for Study of Diabetes. Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care 2009;32:193-203
-
(2009)
Diabetes Care
, vol.32
, pp. 193-203
-
-
Nathan, D.M.1
Buse, J.B.2
Davidson, M.B.3
-
28
-
-
67649111182
-
Trajectories of glycaemia, insulin sensitivity, and insulin secretion before diagnosis of type 2 diabetes: An analysis from the Whitehall II study
-
Tabak AG, Jokela M, Akbaraly TN, Brunner EJ, Kivimäki M, Witte DR. Trajectories of glycaemia, insulin sensitivity, and insulin secretion before diagnosis of type 2 diabetes: an analysis from the Whitehall II study. Lancet 2009;373: 2215-2221
-
(2009)
Lancet
, vol.373
, pp. 2215-2221
-
-
Tabak, A.G.1
Jokela, M.2
Akbaraly, T.N.3
Brunner, E.J.4
Kivimäki, M.5
Witte, D.R.6
-
29
-
-
0028817815
-
Overview of 6 years' therapy of type II diabetes: A progressive disease
-
U.K. Prospective Diabetes Study Group. U.K. prospective diabetes study 16.
-
U.K. Prospective Diabetes Study Group. U.K. prospective diabetes study 16. Overview of 6 years' therapy of type II diabetes: a progressive disease. Diabetes 1995;44:1249-1258
-
(1995)
Diabetes
, vol.44
, pp. 1249-1258
-
-
-
30
-
-
0031961242
-
Beta-cell deterioration determines the onset and rate of progression of secondary dietary failure in type 2 diabetes mellitus: The 10-year follow-up of the Belfast Diet Study
-
Levy J, Atkinson AB, Bell PM, McCance DR, Hadden DR. Beta-cell deterioration determines the onset and rate of progression of secondary dietary failure in type 2 diabetes mellitus: the 10-year follow-up of the Belfast Diet Study. Diabet Med 1998;15:290-296
-
(1998)
Diabet Med
, vol.15
, pp. 290-296
-
-
Levy, J.1
Atkinson, A.B.2
Bell, P.M.3
McCance, D.R.4
Hadden, D.R.5
-
31
-
-
0037219411
-
Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes
-
Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, Butler PC. Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes. Diabetes 2003; 52:102-110
-
(2003)
Diabetes
, vol.52
, pp. 102-110
-
-
Butler, A.E.1
Janson, J.2
Bonner-Weir, S.3
Ritzel, R.4
Rizza, R.A.5
Butler, P.C.6
-
32
-
-
84862516777
-
Pancreatic diabetes manifests when beta cell area declines by approximately 65% in humans
-
Meier JJ, Breuer TGK, Bonadonna RC, et al. Pancreatic diabetes manifests when beta cell area declines by approximately 65% in humans. Diabetologia 2012;55: 1346-1354
-
(2012)
Diabetologia
, vol.55
, pp. 1346-1354
-
-
Meier, J.J.1
Breuer, T.G.K.2
Bonadonna, R.C.3
-
33
-
-
70549113397
-
Role of glucotoxicity and lipotoxicity in the pathophysiology of Type 2 diabetes mellitus and emerging treatment strategies
-
Del Prato S. Role of glucotoxicity and lipotoxicity in the pathophysiology of Type 2 diabetes mellitus and emerging treatment strategies. Diabet Med 2009;26: 1185-1192
-
(2009)
Diabet Med
, vol.26
, pp. 1185-1192
-
-
Del Prato, S.1
-
34
-
-
79959808984
-
Pivotal role of timely basal insulin replacement after metformin failure in sustaining long-term blood glucose control at a target in type 2 diabetes
-
Bolli GB, Lucidi P, Porcellati F, Fanelli CG. Pivotal role of timely basal insulin replacement after metformin failure in sustaining long-term blood glucose control at a target in type 2 diabetes. Diabetes Care 2011;34(Suppl. 2):S220-S224
-
(2011)
Diabetes Care
, vol.34
, Issue.SUPPL. 2
-
-
Bolli, G.B.1
Lucidi, P.2
Porcellati, F.3
Fanelli, C.G.4
-
35
-
-
43849105857
-
Effect of intensive insulin therapy on (3-cell function and glycaemic control in patients with newly diagnosed type 2 diabetes: A multicentre randomised parallel-group trial
-
Weng J, Li Y, Xu W, et al. Effect of intensive insulin therapy on (3-cell function and glycaemic control in patients with newly diagnosed type 2 diabetes: a multicentre randomised parallel-group trial. Lancet 2008;371:1753-1760
-
(2008)
Lancet
, vol.371
, pp. 1753-1760
-
-
Weng, J.1
Li, Y.2
Xu, W.3
-
36
-
-
43849096854
-
Intensive insulin therapy in newly diagnosed type 2 diabetes
-
Retnakaran R, Drucker DJ. Intensive insulin therapy in newly diagnosed type 2 diabetes. Lancet 2008;371:1725-1726
-
(2008)
Lancet
, vol.371
, pp. 1725-1726
-
-
Retnakaran, R.1
Drucker, D.J.2
-
38
-
-
1042291148
-
3.5 years of insulin therapy with insulin glargine improves in vivo endothelial function in type 2 diabetes
-
Vehkavaara S, Yki-Järvinen H. 3.5 years of insulin therapy with insulin glargine improves in vivo endothelial function in type 2 diabetes. Arterioscler Thromb Vasc Biol 2004;24:325-330
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 325-330
-
-
Vehkavaara, S.1
Yki-Järvinen, H.2
-
39
-
-
0032955646
-
Insulin signal transduction: Possible mechanisms for insulin resistance
-
Kellerer M, Lammers R, Häring HU. Insulin signal transduction: possible mechanisms for insulin resistance. Exp Clin Endocrinol Diabetes 1999;107:97-106
-
(1999)
Exp Clin Endocrinol Diabetes
, vol.107
, pp. 97-106
-
-
Kellerer, M.1
Lammers, R.2
Häring, H.U.3
-
40
-
-
0017236889
-
Relationships between fasting plasma glucose levels and insulin secretion during intravenous glucose tolerance tests
-
Brunzell JD, Robertson RP, Lerner RL, et al. Relationships between fasting plasma glucose levels and insulin secretion during intravenous glucose tolerance tests. J Clin Endocrinol Metab 1976;42: 222-229
-
(1976)
J Clin Endocrinol Metab
, vol.42
, pp. 222-229
-
-
Brunzell, J.D.1
Robertson, R.P.2
Lerner, R.L.3
-
41
-
-
82155198455
-
Chronic reduction of fasting glycemia with insulin glargine improves first-and second-phase insulin secretion in patients with type 2 diabetes
-
Pennartz C, Schenker N, Menge BA, Schmidt WE, Nauck MA, Meier JJ. Chronic reduction of fasting glycemia with insulin glargine improves first-and second-phase insulin secretion in patients with type 2 diabetes. Diabetes Care 2011; 34:2048-2053
-
(2011)
Diabetes Care
, vol.34
, pp. 2048-2053
-
-
Pennartz, C.1
Schenker, N.2
Menge, B.A.3
Schmidt, W.E.4
Nauck, M.A.5
Meier, J.J.6
-
42
-
-
77952037659
-
Adding insulin glargine vs NPH insulin to metformin results in a more efficient postprandial b-cell protection in individuals with type 2 diabetes
-
Forst T, Larbig M, Hohberg C, et al. Adding insulin glargine vs. NPH insulin to metformin results in a more efficient postprandial b-cell protection in individuals with type 2 diabetes. Diabetes Obes Metab 2010;12:437-441
-
(2010)
Diabetes Obes Metab
, vol.12
, pp. 437-441
-
-
Forst, T.1
Larbig, M.2
Hohberg, C.3
-
43
-
-
38449097526
-
Advancing therapy in type 2 diabetes mellitus with early, comprehensive progression from oral agents to insulin therapy
-
Vinik A. Advancing therapy in type 2 diabetes mellitus with early, comprehensive progression from oral agents to insulin therapy. Clin Ther 2009;29:1236-1253
-
(2009)
Clin Ther
, vol.29
, pp. 1236-1253
-
-
Vinik, A.1
-
44
-
-
35548947584
-
Addition of biphasic prandial or basal insulin to oral therapy in type 2 diabetes
-
4-T Study Group
-
Holman RR, Thorne KI, Farmer AJ, et al.; 4-T Study Group. Addition of biphasic, prandial, or basal insulin to oral therapy in type 2 diabetes. N Engl J Med 2007;357: 1716-1730
-
(2007)
N Engl J Med
, vol.357
, pp. 1716-1730
-
-
Holman, R.R.1
Thorne, K.I.2
Farmer, A.J.3
-
45
-
-
40949111213
-
Once-daily basal insulin glargine versus thrice-daily prandial insulin lispro in people with type 2 diabetes on oral hypoglycaemic agents (APOLLO): An open randomised controlled trial
-
Bretzel RG, Nuber U, Landgraf W, Owens DR, Bradley C, Linn T. Once-daily basal insulin glargine versus thrice-daily prandial insulin lispro in people with type 2 diabetes on oral hypoglycaemic agents (APOLLO): an open randomised controlled trial. Lancet 2008;371:1073-1084
-
(2008)
Lancet
, vol.371
, pp. 1073-1084
-
-
Bretzel, R.G.1
Nuber, U.2
Landgraf, W.3
Owens, D.R.4
Bradley, C.5
Linn, T.6
-
46
-
-
68849084773
-
Expertengruppe der Osterreichischen Diabetesgesellschaft.
-
[in German]
-
Ludvik B, Brath H, Wascher T, Toplak H; Expertengruppe der Osterreichischen Diabetesgesellschaft. The significance of long acting insulin analogues in the treatment of type 2 diabetes mellitus. Wien Klin Wochenschr 2009;121:473-482 [in German]
-
(2009)
Wien Klin Wochenschr
, vol.121
, pp. 473-482
-
-
Ludvik, B.1
Brath, H.2
Wascher, T.3
Toplak, H.4
-
47
-
-
53749102150
-
Nocturnal glucose metabolism after bedtime injection of insulin glargine or neutral protamine hagedorn insulin in patients with type 2 diabetes
-
Linn T, Fischer B, Soydan N, et al. Nocturnal glucose metabolism after bedtime injection of insulin glargine or neutral protamine hagedorn insulin in patients with type 2 diabetes. J Clin Endocrinol Metab 2008;93:3839-3846
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 3839-3846
-
-
Linn, T.1
Fischer, B.2
Soydan, N.3
-
48
-
-
67949100214
-
Comparison of treatment costs in inadequately controlled type 2 diabetes in Germany based on the APOLLO trial with insulin glargine
-
Bretzel RG, Dippel FW, Linn T, Neilson AR. Comparison of treatment costs in inadequately controlled type 2 diabetes in Germany based on the APOLLO trial with insulin glargine. J Media Econ 2009;12:1-11
-
(2009)
J Media Econ
, vol.12
, pp. 1-11
-
-
Bretzel, R.G.1
Dippel, F.W.2
Linn, T.3
Neilson, A.R.4
-
49
-
-
84891790147
-
Resistance to insulin therapy among patients and providers: Results of the cross-national Diabetes Attitudes Wishes and Needs (DAWN) study
-
The International DAWN Advisory Panel.
-
Peyrot M, Rubin RR, Lauritzen T, et al.; The International DAWN Advisory Panel. Resistance to insulin therapy among patients and providers: results of the cross-national Diabetes Attitudes, Wishes, and Needs (DAWN) study. Diabetes Care 2005;29:952-953
-
(2005)
Diabetes Care
, vol.29
, pp. 952-953
-
-
Peyrot, M.1
Rubin, R.R.2
Lauritzen, T.3
-
50
-
-
67949084828
-
Initiating insulin therapy in type 2 diabetic patients failing on oral hypoglycemic agents: Basal or prandial insulin? the APOLLO trial and beyond
-
Bretzel RG, Eckhard M, Landgraf W, Owens DR, Linn T. Initiating insulin therapy in type 2 diabetic patients failing on oral hypoglycemic agents: basal or prandial insulin? The APOLLO trial and beyond. Diabetes Care 2009;32(Suppl. 2):S260-S265
-
(2009)
Diabetes Care
, vol.32
, Issue.SUPPL. 2
-
-
Bretzel, R.G.1
Eckhard, M.2
Landgraf, W.3
Owens, D.R.4
Linn, T.5
-
51
-
-
77950891085
-
Effect of noninsulin antidi-abetic drugs added to metformin therapy on glycemic control, weight gain, and hypoglycemia in type 2 diabetes
-
Phung OJ, Scholle JM, Talwar M, Coleman CI. Effect of noninsulin antidi-abetic drugs added to metformin therapy on glycemic control, weight gain, and hypoglycemia in type 2 diabetes. JAMA 2010;303:1410-1418
-
(2010)
JAMA
, vol.303
, pp. 1410-1418
-
-
Phung, O.J.1
Scholle, J.M.2
Talwar, M.3
Coleman, C.I.4
-
52
-
-
79960758089
-
An analysis of early insulin glargine added to metformin with or without sulfonylurea: Impact on glycaemic control and hypo-glycaemia
-
Fonseca V, Gill J, Zhou R, Leahy J. An analysis of early insulin glargine added to metformin with or without sulfonylurea: impact on glycaemic control and hypo-glycaemia. Diabetes Obes Metab 2011;13: 814-822
-
(2011)
Diabetes Obes Metab
, vol.13
, pp. 814-822
-
-
Fonseca, V.1
Gill, J.2
Zhou, R.3
Leahy, J.4
-
53
-
-
0242269000
-
The treat-to-target trial: Randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetic patients
-
Insulin Glargine 4002 Study Investigators
-
Riddle MC, Rosenstock J, Gerich J; Insulin Glargine 4002 Study Investigators. The treat-to-target trial: randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetic patients. Diabetes Care 2003;26:3080-3086
-
(2003)
Diabetes Care
, vol.26
, pp. 3080-3086
-
-
Riddle, M.C.1
Rosenstock, J.2
Gerich, J.3
-
54
-
-
33748522381
-
A randomized trial of adding insulin glargine vs.avoidance of insulin in people with Type 2 diabetes on either no oral glucose-lowering agents or submaximal doses of metformin and/or sulphonylureas, the Canadian INSIGHT (Implementing New Strategies with Insulin Glargine for Hyperglycaemia Treatment) Study
-
Gerstein HC, Yale J-F, Harris SB, Issa M, Stewart JA, Dempsey E. A randomized trial of adding insulin glargine vs. avoidance of insulin in people with Type 2 diabetes on either no oral glucose-lowering agents or submaximal doses of metformin and/or sulphonylureas. The Canadian INSIGHT (Implementing New Strategies with Insulin Glargine for Hyperglycaemia Treatment) Study. Diabet Med 2006;23: 736-742
-
(2006)
Diabet Med
, vol.23
, pp. 736-742
-
-
Gerstein, H.C.1
Yale, J.-F.2
Harris, S.B.3
Issa, M.4
Stewart, J.A.5
Dempsey, E.6
-
55
-
-
33244479164
-
Insulin glargine or NPH combined with metformin in type 2 diabetes: The LANMET study
-
Yki-Järvinen H, Kauppinen-Mäkelin R, Tiikkainen M, et al. Insulin glargine or NPH combined with metformin in type 2 diabetes: the LANMET study. Diabetologia 2006;49:442-451
-
(2006)
Diabetologia
, vol.49
, pp. 442-451
-
-
Yki-Järvinen, H.1
Kauppinen-Mäkelin, R.2
Tiikkainen, M.3
-
56
-
-
34249903872
-
Initiate Insulin by Aggressive Titra-tion and Education (INITIATE): A randomized study to compare initiation of insulin combination therapy in type 2 diabetic patients individually and in groups
-
Yki-Järvinen H, Juurinen L, Alvarsson M, et al. Initiate Insulin by Aggressive Titra-tion and Education (INITIATE): a randomized study to compare initiation of insulin combination therapy in type 2 diabetic patients individually and in groups. Diabetes Care 2007;30:1364-1369
-
(2007)
Diabetes Care
, vol.30
, pp. 1364-1369
-
-
Yki-Järvinen, H.1
Juurinen, L.2
Alvarsson, M.3
-
57
-
-
33644873468
-
Impact of active versus usual algorithmic titration of basal insulin and point-of-care versus laboratory measurement of HbA1c on glycemic control in patients with type 2 diabetes: The Glycemic Optimization with Algorithms and Labs at Point of Care (GOAL A1C) trial
-
GOAL AIC Team
-
Kennedy L, Herman WH, Strange P, Harris A; GOAL AIC Team. Impact of active versus usual algorithmic titration of basal insulin and point-of-care versus laboratory measurement of HbA1c on glycemic control in patients with type 2 diabetes: the Glycemic Optimization with Algorithms and Labs at Point of Care (GOAL A1C) trial. Diabetes Care2006;29: 1-8
-
(2006)
Diabetes Care
, vol.29
, pp. 1-8
-
-
Kennedy, L.1
Herman, W.H.2
Strange, P.3
Harris, A.4
-
58
-
-
33845540867
-
Insulin glargine benefits patients with type 2 diabetes inadequately controlled on oral antidia-betic treatment: An observational study of everyday practice in 12, 216 patients
-
Schreiber SA, Haak T. Insulin glargine benefits patients with type 2 diabetes inadequately controlled on oral antidia-betic treatment: an observational study of everyday practice in 12, 216 patients. Diabetes Obes Metab 2007;9:31-38
-
(2007)
Diabetes Obes Metab
, vol.9
, pp. 31-38
-
-
Schreiber, S.A.1
Haak, T.2
-
59
-
-
38949129060
-
The long-term efficacy of insulin glargine plus oral antidiabetic agents in a 32-month observational study of everyday clinical practice
-
Schreiber SA, Ferlinz K, Haak T. The long-term efficacy of insulin glargine plus oral antidiabetic agents in a 32-month observational study of everyday clinical practice. Diabetes Technol Ther 2008; 10:121-127
-
(2008)
Diabetes Technol Ther
, vol.10
, pp. 121-127
-
-
Schreiber, S.A.1
Ferlinz, K.2
Haak, T.3
-
60
-
-
84860761633
-
EARLY study: Early basal insulin therapy under real-life conditions in type 2 diabetics
-
Hanefeld M, Fleischmann H, Landgraf W, Pistrosch F. EARLY study: early basal insulin therapy under real-life conditions in type 2 diabetics. Diabetes Stoffw Herz 2012;21:91-97
-
(2012)
Diabetes Stoffw Herz
, vol.21
, pp. 91-97
-
-
Hanefeld, M.1
Fleischmann, H.2
Landgraf, W.3
Pistrosch, F.4
-
61
-
-
84855408801
-
Strategies for insulin initiation: Insights from the French LIGHT observational study
-
Vergès B, Brun JM, Tawil C, Alexandre B, Kerlan V. Strategies for insulin initiation: insights from the French LIGHT observational study. Diabetes Metab Res Rev 2012;28:97-105
-
(2012)
Diabetes Metab Res Rev
, vol.28
, pp. 97-105
-
-
Vergès, B.1
Brun, J.M.2
Tawil, C.3
Alexandre, B.4
Kerlan, V.5
-
62
-
-
84863809670
-
Dosing of insulin glargine to achieve the treatment target in Japanese type 2 diabetes on a basal supported oral therapy regimen in real life: ALOHA study sub-analysis
-
Odawara M, Ohtani T, Kadowaki T. Dosing of insulin glargine to achieve the treatment target in Japanese type 2 diabetes on a basal supported oral therapy regimen in real life: ALOHA study sub-analysis. Diabetes Technol Ther 2012;14: 635-643
-
(2012)
Diabetes Technol Ther
, vol.14
, pp. 635-643
-
-
Odawara, M.1
Ohtani, T.2
Kadowaki, T.3
-
63
-
-
85058248734
-
Rationale, design, and baseline characteristics for a large international trial of cardiovascular disease prevention in people with dysglycemia: The ORIGIN Trial (Outcome Reduction with an Initial Glargine Intervention)
-
The ORIGIN Trial Investigators
-
The ORIGIN Trial Investigators. Rationale, design, and baseline characteristics for a large international trial of cardiovascular disease prevention in people with dysglycemia: The ORIGIN Trial (Outcome Reduction with an Initial Glargine Intervention). Am Heart J 2008;155: 26-32
-
(2008)
Am Heart J
, vol.155
, pp. 26-32
-
-
-
64
-
-
77953821528
-
Diabetes mellitus fasting blood glucose concentration and risk of vascular disease: A collaborative meta-analysis of 102 prospective studies
-
Emerging Risk Factors Collaboration.
-
Sarwar N, Gao P, Seshasai SR, et al.; Emerging Risk Factors Collaboration. Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies. Lancet 2010;375: 2215-2222
-
(2010)
Lancet
, vol.375
, pp. 2215-2222
-
-
Sarwar, N.1
Gao, P.2
Seshasai, S.R.3
-
65
-
-
33846414720
-
Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: Executive summary
-
Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC); European Association for the Study of Diabetes (EASD).
-
Rydén L, Standl E, Bartnik M, et al.; Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC); European Association for the Study of Diabetes (EASD). Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: executive summary. Eur Heart J 2007;28:88-136
-
(2007)
Eur Heart J
, vol.28
, pp. 88-136
-
-
Rydén, L.1
Standl, E.2
Bartnik, M.3
-
66
-
-
84857029848
-
Proportion of patients at HbA1c target, 7% with eight classes of antidiabetic drugs in type 2 diabetes: Systematic review of 218 randomized controlled trials with 78 945 patients
-
Esposito K, Chiodini P, Bellastella G, Maiorino MI, Giugliano D. Proportion of patients at HbA1c target, 7% with eight classes of antidiabetic drugs in type 2 diabetes: systematic review of 218 randomized controlled trials with 78 945 patients. Diabetes Obes Metab 2012;14: 228-233
-
(2012)
Diabetes Obes Metab
, vol.14
, pp. 228-233
-
-
Esposito, K.1
Chiodini, P.2
Bellastella, G.3
Maiorino, M.I.4
Giugliano, D.5
-
67
-
-
34249807045
-
When basal insulin therapy in type 2 diabetes mellitus is not enoughdwhat next?
-
Raccah D, Bretzel RG, Owens D, Riddle M. When basal insulin therapy in type 2 diabetes mellitus is not enoughdwhat next? Diabetes Metab Res Rev 2007;23:257-264
-
(2007)
Diabetes Metab Res Rev
, vol.23
, pp. 257-264
-
-
Raccah, D.1
Bretzel, R.G.2
Owens, D.3
Riddle, M.4
-
68
-
-
84861889012
-
Non-insulin injectable treatments (glucagon-like pep-tide-1 and its analogs) and cardiovascular disease
-
Lebovitz HE, Banerji MA. Non-insulin injectable treatments (glucagon-like pep-tide-1 and its analogs) and cardiovascular disease. Diabetes Technol Ther 2012;14 (Suppl. 1):S43-S50
-
(2012)
Diabetes Technol Ther
, vol.14
, Issue.SUPPL. 1
-
-
Lebovitz, H.E.1
Banerji, M.A.2
-
69
-
-
68649099986
-
Exenatide added to insulin therapy: A retrospective review of clinical practice over two years in an academic endocrinology outpatient setting
-
Yoon NM, Cavaghan MK, Brunelle RL, Roach P. Exenatide added to insulin therapy: a retrospective review of clinical practice over two years in an academic endocrinology outpatient setting. Clin Ther 2009;31:1511-1523
-
(2009)
Clin Ther
, vol.31
, pp. 1511-1523
-
-
Yoon, N.M.1
Cavaghan, M.K.2
Brunelle, R.L.3
Roach, P.4
-
70
-
-
77955262909
-
Further improvement in postprandial glucose control with addition of exenatide or sitagliptin to combination therapy with insulin glargine and metformin: A proof-of-concept study
-
Arnolds S, Dellweg S, Clair J, et al. Further improvement in postprandial glucose control with addition of exenatide or sitagliptin to combination therapy with insulin glargine and metformin: a proof-of-concept study. Diabetes Care 2010;33: 1509-1515
-
(2010)
Diabetes Care
, vol.33
, pp. 1509-1515
-
-
Arnolds, S.1
Dellweg, S.2
Clair, J.3
-
71
-
-
79551615182
-
Use of twice-daily exenatide in basal insulin-treated patients with type 2 diabetes
-
Buse JB, Bergenstal RM, Glass LC, et al. Use of twice-daily exenatide in basal insulin-treated patients with type 2 diabetes. Ann Intern Med 2011;154: 1-11
-
(2011)
Ann Intern Med
, vol.154
, pp. 1-11
-
-
Buse, J.B.1
Bergenstal, R.M.2
Glass, L.C.3
-
72
-
-
67349251550
-
Megatrials in type 2 diabetes. from excitement to frustration?
-
Del Prato S. Megatrials in type 2 diabetes. From excitement to frustration? Dia-betologia 2009;52:1219-1226
-
(2009)
Dia-betologia
, vol.52
, pp. 1219-1226
-
-
Del Prato, S.1
|