Light microscopy is useful to better define NERD and functional heartburn

Gut

Volumn 63, Issue 2, 2014, Pages 368-

  Savarino, Edoardo ^a   Zentilin, Patrizia ^b   Mastracci, Luca ^c   Fiocca, Roberto ^c   Savarino, Vincenzo ^b  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACID;

ACIDITY; ELECTRON MICROSCOPY; ESOPHAGITIS; HEARTBURN; HISTOPATHOLOGY; HUMAN; IMPEDANCE; MICROSCOPY; NON EROSIVE REFLUX DISEASE; NOTE; PH; PRIORITY JOURNAL;

EID: 84891746545     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2013-305955     Document Type: Note

References (6)

1. Woodland P, Al-Zinaty M, Yazaki E, et al. In vivo evaluation of acid-induced changes in oesophageal mucosa integrity and sensitivity in non-erosive reflux disease. Gut 2013;62:1256-61.
2. Savarino E, Pohl D, Zentilin P, et al. Functional heartburn has more in common with functional dyspepsia than with non-erosive reflux disease. Gut 2009;58:1185-91.
3. Savarino E, Zentilin P, Savarino V. NERD: an umbrella term including heterogeneous subpopulations. Nat Rev Gastroenterol Hepatol 2013;10:371-80.
4. Zentilin P, Savarino V, Mastracci L, et al. Reassessment of the diagnostic value of histology in patients with GERD, using multiple biopsy sites and an appropriate control group. Am J Gastroenterol 2005;100:2299-306.
5. Savarino E, Zentilin P, Mastracci L, et al. Microscopic esophagitis distinguishes patients with non-erosive reflux disease from those with functional heartburn. J Gastroenterol 2013;48:473-82.
6. Kandulski A, Jechorek D, Caro C, et al. Histomorphological differentiation of non-erosive reflux disease and functional heartburn in patients with PPI-refractory heartburn. Aliment Pharmacol Ther 2013;38:643-51.