메뉴 건너뛰기




Volumn 31, Issue 32, 2013, Pages 4160-4161

Statins may protect against hepatocellular carcinoma development in patients infected with hepatitis C virus, but what are the mechanisms?

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LIPID; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE;

EID: 84891724290     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2013.51.0354     Document Type: Letter
Times cited : (4)

References (20)
  • 1
    • 84876516919 scopus 로고    scopus 로고
    • Statins and the risk of hepatocellular carcinoma in patients with hepatitis C virus infection
    • Tsan YT, Lee CH, Ho WC, et al: Statins and the risk of hepatocellular carcinoma in patients with hepatitis C virus infection. J Clin Oncol 31:1514-1521, 2013
    • (2013) J Clin Oncol , vol.31 , pp. 1514-1521
    • Tsan, Y.T.1    Lee, C.H.2    Ho, W.C.3
  • 2
    • 84876522739 scopus 로고    scopus 로고
    • An ounce of prevention is better than a pound of cure: A patient-centered approach to hepatocellular carcinoma
    • Siegel AB: An ounce of prevention is better than a pound of cure: A patient-centered approach to hepatocellular carcinoma. J Clin Oncol 31:1499-1501, 2013
    • (2013) J Clin Oncol , vol.31 , pp. 1499-1501
    • Siegel, A.B.1
  • 3
    • 65249190240 scopus 로고    scopus 로고
    • Statins are associated with a reduced risk of hepatocellular carcinoma in a large cohort of patients with diabetes
    • El-Serag HB, Johnson ML, Hachem C, et al: Statins are associated with a reduced risk of hepatocellular carcinoma in a large cohort of patients with diabetes. Gastroenterology 136:1601-1608, 2009
    • (2009) Gastroenterology , vol.136 , pp. 1601-1608
    • El-Serag, H.B.1    Johnson, M.L.2    Hachem, C.3
  • 4
    • 84863115964 scopus 로고    scopus 로고
    • Statins and the risk of hepatocellular carcinoma in patients with hepatitis B virus infection
    • Tsan YT, Lee CH, Wang JD, et al: Statins and the risk of hepatocellular carcinoma in patients with hepatitis B virus infection. J Clin Oncol 30:623-630, 2012
    • (2012) J Clin Oncol , vol.30 , pp. 623-630
    • Tsan, Y.T.1    Lee, C.H.2    Wang, J.D.3
  • 7
    • 33745903898 scopus 로고    scopus 로고
    • Different anti-HCV profiles of statins and their potential for combination therapy with interferon
    • DOI 10.1002/hep.21232
    • Ikeda M, Abe K, Yamada M, et al: Different anti-HCV profiles of statins and their potential for combination therapy with interferon. Hepatology 44:117-125, 2006 (Pubitemid 44049145)
    • (2006) Hepatology , vol.44 , Issue.1 , pp. 117-125
    • Ikeda, M.1    Abe, K.-I.2    Yamada, M.3    Dansako, H.4    Naka, K.5    Kato, N.6
  • 9
    • 84882890676 scopus 로고    scopus 로고
    • PTEN protein phosphatase activity regulates hepatitis C virus secretion through modulation of cholesterol metabolism
    • Peyrou M, Clément S, Maier C, et al: PTEN protein phosphatase activity regulates hepatitis C virus secretion through modulation of cholesterol metabolism. J Hepatol 59:420-426, 2013
    • (2013) J Hepatol , vol.59 , pp. 420-426
    • Peyrou, M.1    Clément, S.2    Maier, C.3
  • 10
    • 78650457786 scopus 로고    scopus 로고
    • Statin therapy improves sustained virologic response among diabetic patients with chronic hepatitis C
    • Rao GA, Pandya PK: Statin therapy improves sustained virologic response among diabetic patients with chronic hepatitis C. Gastroenterology 140:144-152, 2011
    • (2011) Gastroenterology , vol.140 , pp. 144-152
    • Rao, G.A.1    Pandya, P.K.2
  • 11
    • 79959537058 scopus 로고    scopus 로고
    • Down-regulation of phosphatase and tensin homolog by hepatitis C virus core 3a in hepatocytes triggers the formation of large lipid droplets
    • Clement S, Peyrou M, Sanchez-Pareja A, et al: Down-regulation of phosphatase and tensin homolog by hepatitis C virus core 3a in hepatocytes triggers the formation of large lipid droplets. Hepatology 54:38-49, 2011
    • (2011) Hepatology , vol.54 , pp. 38-49
    • Clement, S.1    Peyrou, M.2    Sanchez-Pareja, A.3
  • 12
    • 79952450963 scopus 로고    scopus 로고
    • Non-genomic loss of PTEN function in cancer: Not in my genes
    • Leslie NR, Foti M: Non-genomic loss of PTEN function in cancer: Not in my genes. Trends Pharmacol Sci 32:131-140, 2011
    • (2011) Trends Pharmacol Sci , vol.32 , pp. 131-140
    • Leslie, N.R.1    Foti, M.2
  • 13
    • 78650027929 scopus 로고    scopus 로고
    • Haplo-insufficiency: A driving force in cancer
    • Berger AH, Pandolfi PP: Haplo-insufficiency: A driving force in cancer. J Pathol 223:137-146, 2011
    • (2011) J Pathol , vol.223 , pp. 137-146
    • Berger, A.H.1    Pandolfi, P.P.2
  • 15
    • 37349083834 scopus 로고    scopus 로고
    • PTEN Down-Regulation by Unsaturated Fatty Acids Triggers Hepatic Steatosis via an NF-kappaBp65/mTOR-Dependent Mechanism
    • DOI 10.1053/j.gastro.2007.10.010, PII S0016508507018094
    • Vinciguerra M, Veyrat-Durebex C, Moukil MA, et al: PTEN down-regulation by unsaturated fatty acids triggers hepatic steatosis via an NF-kappaBp65/mTOR-dependent mechanism. Gastroenterology 134:268-280, 2008 (Pubitemid 350309315)
    • (2008) Gastroenterology , vol.134 , Issue.1 , pp. 268-280
    • Vinciguerra, M.1    Veyrat-Durebex, C.2    Moukil, M.A.3    Rubbia-Brandt, L.4    Rohner-Jeanrenaud, F.5    Foti, M.6
  • 16
    • 0037054934 scopus 로고    scopus 로고
    • Impact of PTEN expression on the outcome of hepatitis C virus-positive cirrhotic hepatocellular carcinoma patients: Possible relationship with COX II and inducible nitric oxide synthase
    • DOI 10.1002/ijc.10458
    • Rahman MA, Kyriazanos ID, Ono T, et al: Impact of PTEN expression on the outcome of hepatitis C virus-positive cirrhotic hepatocellular carcinoma patients: Possible relationship with COX II and inducible nitric oxide synthase. Int J Cancer 100:152-157, 2002 (Pubitemid 34666188)
    • (2002) International Journal of Cancer , vol.100 , Issue.2 , pp. 152-157
    • Rahman, M.A.1    Kyriazanos, I.D.2    Ono, T.3    Yamanoi, A.4    Kohno, H.5    Tsuchiya, M.6    Nagasue, N.7
  • 17
    • 80052825683 scopus 로고    scopus 로고
    • HCV genotype 3 is associated with a higher hepatocellular carcinoma incidence in patients with ongoing viral C cirrhosis
    • Nkontchou G, Ziol M, Aout M, et al: HCV genotype 3 is associated with a higher hepatocellular carcinoma incidence in patients with ongoing viral C cirrhosis. J Viral Hepat 18:516-522, 2011
    • (2011) J Viral Hepat , vol.18 , pp. 516-522
    • Nkontchou, G.1    Ziol, M.2    Aout, M.3
  • 18
    • 84871487025 scopus 로고    scopus 로고
    • Association between sustained virological response and all-cause mortality among patients with chronic hepatitis C and advanced hepatic fibrosis
    • van der Meer AJ, Veldt BJ, Feld JJ, et al: Association between sustained virological response and all-cause mortality among patients with chronic hepatitis C and advanced hepatic fibrosis. JAMA 308:2584-2593, 2012
    • (2012) JAMA , vol.308 , pp. 2584-2593
    • Van Der Meer, A.J.1    Veldt, B.J.2    Feld, J.J.3
  • 20
    • 34250339305 scopus 로고    scopus 로고
    • Hepatic steatosis is associated with increased frequency of hepatocellular carcinoma in patients with hepatitis C-related cirrhosis
    • DOI 10.1002/cncr.22701
    • Pekow JR, Bhan AK, Zheng H, et al: Hepatic steatosis is associated with increased frequency of hepatocellular carcinoma in patients with hepatitis C-related cirrhosis. Cancer 109:2490-2496, 2007 (Pubitemid 46908652)
    • (2007) Cancer , vol.109 , Issue.12 , pp. 2490-2496
    • Pekow, J.R.1    Bhan, A.K.2    Zheng, H.3    Chung, R.T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.