Evaluation of clinical outcomes in patients with dry eye disease using lubricant eye drops containing polyethylene glycol or carboxymethylcellulose

Clinical Ophthalmology

Volumn 8, Issue , 2013, Pages 157-164

  Cohen, Stephen ^a   Martin, Anna ^b   Sall, Kenneth ^c  

^a Cohen Optometry ^*  (United States)

^b Alcon Research Inc   (United States)

^c Sall Rresearch Medical Center Inc   (United States)

Author keywords

Artificial tears; Corneal staining; Patient reported outcomes; Refresh Liquigel; Systane Gel Drops

Indexed keywords

CARBOXYMETHYLCELLULOSE; EYE DROPS; LUBRICATING AGENT; MACROGOL; REFRESH LIQUIGEL; SYSTANE; UNCLASSIFIED DRUG;

ABNORMAL SENSATION; AGED; ALLERGY; ARTICLE; CLINICAL EFFECTIVENESS; CONJUNCTIVAL STAINING; CONTROLLED STUDY; CORNEAL STAINING; DISEASE ASSOCIATION; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; DRY EYE; EYE ALLERGY; EYE IRRITATION; EYE PAIN; EYELID DISEASE; FEMALE; FOREIGN BODY; HUMAN; INTENTION TO TREAT ANALYSIS; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; OCULAR PRURITUS; OUTCOME ASSESSMENT; PATIENT ASSESSMENT; RANDOMIZED CONTROLLED TRIAL; RHINOPHARYNGITIS; SCORING SYSTEM; SEASONAL ALLERGY; STAINING; TEAR FILM; UPPER RESPIRATORY TRACT INFECTION; VISUAL ACUITY;

EID: 84891705461     PISSN: 11775467     EISSN: 11775483     Source Type: Journal    
DOI: 10.2147/OPTH.S53822     Document Type: Article

References (19)

1. Lemp MA, Crews LA, Bron AJ, Foulks GN, Sullivan BD. Distribution of aqueous-deficient and evaporative dry eye in a clinic-based patient cohort: a retrospective study. Cornea. 2012;31(5):472-478.
2. Gayton JL. Etiology, prevalence, and treatment of dry eye disease. Clin Ophthalmol. 2009;3:405-412.
3. International Dry Eye Workshop. The definition and classification of dry eye disease: report of the Definition and Classification Subcommittee of the International Dry Eye Workshop. Ocul Surf. 2007;5(2):75-92.
4. McGinnigle S, Naroo SA, Eperjesi F. Evaluation of dry eye. Surv Ophthalmol. 2012;57(4):293-316.
5. Jacobi C, Kruse FE, Cursiefen C. Prospective, randomized, controlled comparison of Systane UD eye drops versus Visine Intensiv 1% EDO eye drops for the treatment of moderate dry eye. J Ocul Pharmacol Ther. 2012;28(6):598-603.
6. Sullivan DA, Hammitt KM, Schaumberg DA, et al. Report of the TFOS/ARVO Symposium on global treatments for dry eye disease: an unmet need. Ocul Surf. 2012;10(2):108-116.
7. Cuevas M, Gonzalez-Garcia MJ, Castellanos E, et al. Correlations among symptoms, signs, and clinical tests in evaporative-type dry eye disease caused by Meibomian gland dysfunction (MGD). Curr Eye Res. 2012;37(10):855-863.
8. Sullivan BD, Crews LA, Sonmez B, et al. Clinical utility of objective tests for dry eye disease: variability over time and implications for clinical trials and disease management. Cornea. 2012;31(9):1000-1008.
9. Sullivan BD, Crews LA, Messmer EM, et al. Correlations between commonly used objective signs and symptoms for the diagnosis of dry eye disease: clinical implications. Acta Ophthalmol. December 28, 2012. [Epub ahead of print.]
10. Lemp MA, Bron AJ, Baudouin C, et al. Tear osmolarity in the diagnosis and management of dry eye disease. Am J Ophthalmol. 2011;151(5): 792-798. e791.
11. Sullivan BD, Whitmer D, Nichols KK, et al. An objective approach to dry eye disease severity. Invest Ophthalmol Vis Sci. 2010;51(12):6125-6130.
12. Benelli U. Systane lubricant eye drops in the management of ocular dryness. Clin Ophthalmol. 2011;5:783-790.
13. International Dry Eye Workshop. Design and conduct of clinical trials: report of the Clinical Trials Subcommittee of the International Dry Eye Workshop. Ocul Surf. 2007;5(2):153-162.
14. Stevenson W, Chauhan SK, Dana R. Dry eye disease: an immune-mediated ocular surface disorder. Arch Ophthalmol. 2012;130(1):90-100.
15. Nichols KK. Patient-reported symptoms in dry dye disease. Ocul Surf. 2006;4(3):137-145.
16. International Dry Eye Workshop. Methodologies to diagnose and monitor dry eye disease: report of the Diagnostic Methodology Subcommittee of the International Dry Eye Workshop. Ocul Surf. 2007;5(2): 108-152.
17. Nichols KK, Mitchell GL, Zadnik K. The repeatability of clinical measurements of dry eye. Cornea. 2004;23(3):272-285.
18. Wang TJ, Wang IJ, Ho JD, et al. Comparison of the clinical effects of carbomer-based lipid-containing gel and hydroxypropyl-guar gel artificial tear formulations in patients with dry eye syndrome: a 4-week, prospective, open-label, randomized, parallel-group, noninferiority study. Clin Ther. 2010;32(1):44-52.
19. Savini G, Prabhawasat P, Kojima T, et al. The challenge of dry eye diagnosis. Clin Ophthalmol. 2008;2(1):31-55.