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Volumn 2013, Issue 5, 2013, Pages

Combination inhaled steroid and long-acting beta2-agonist versus tiotropium for chronic obstructive pulmonary disease

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CORTICOSTEROID; FLUTICASONE; SALMETEROL; STEROID; TIOTROPIUM BROMIDE; ANDROSTANE DERIVATIVE; BRONCHODILATING AGENT; DRUG DERIVATIVE; SALBUTAMOL; SCOPOLAMINE DERIVATIVE; BETA ADRENERGIC RECEPTOR STIMULATING AGENT;

EID: 84891695294     PISSN: 14651858     EISSN: None     Source Type: Journal    
DOI: 10.1002/14651858.CD007891.pub3     Document Type: Review
Times cited : (47)

References (70)
  • 2
    • 85041532578 scopus 로고    scopus 로고
    • Adverse events and mortality in the INSPIRE study (investigating new standards for prophylaxis in reduction of exacerbations) [Abstract]
    • Calverley P, Stockley R, Seemungal T, Hagan G, Wedzicha J. Adverse events and mortality in the INSPIRE study (investigating new standards for prophylaxis in reduction of exacerbations) [Abstract]. European Respiratory Journal 2007;30(Suppl 51):125s [P847].
    • (2007) European Respiratory Journal , vol.30 , pp. 125s
    • Calverley, P.1    Stockley, R.2    Seemungal, T.3    Hagan, G.4    Wedzicha, J.5
  • 4
    • 85041553787 scopus 로고    scopus 로고
    • Multicentre, randomised, double-blind, double dummy, parallel group, 104-week study to compare the effect of the salmeterol/fluticasone propionate combination product (SERETIDE*) 50/500mcg delivered twice daily via the DISKUS*/ACCUHALER* inhaler with tiotropium bromide 18 mcg delivered once daily via the Handihaler inhalation device on the rate of health care utilisation exacerbations in subjects with severe chronic obstructive pulmonary disease (COPD)
    • (accessed 16 June 2009)
    • GSK (SCO40036). Multicentre, randomised, double-blind, double dummy, parallel group, 104-week study to compare the effect of the salmeterol/fluticasone propionate combination product (SERETIDE*) 50/500mcg delivered twice daily via the DISKUS*/ACCUHALER* inhaler with tiotropium bromide 18 mcg delivered once daily via the Handihaler inhalation device on the rate of health care utilisation exacerbations in subjects with severe chronic obstructive pulmonary disease (COPD). www.gsk-clinicalstudyregister.com/files/pdf/21085.pdf (accessed 16 June 2009).
  • 5
    • 85041543258 scopus 로고    scopus 로고
    • Effect of fluticasone/salmeterol propionate versus tiotropium bromide on exacerbations: the INSPIRE study (investigating new standards for prophylaxis in reduction of exacerbations) [Abstract]
    • Seemungal T, Stockley R, Calverley P, Hagan G, Wedzicha J. Effect of fluticasone/salmeterol propionate versus tiotropium bromide on exacerbations: the INSPIRE study (investigating new standards for prophylaxis in reduction of exacerbations) [Abstract]. European Respiratory Journal 2007;30(Suppl 51):688s [E4055].
    • (2007) European Respiratory Journal , vol.30 , pp. 688s
    • Seemungal, T.1    Stockley, R.2    Calverley, P.3    Hagan, G.4    Wedzicha, J.5
  • 7
    • 79551650867 scopus 로고    scopus 로고
    • Effect of fluticasone/salmeterol propionate versus tiotropium bromide on withdrawal rate, health status, lung function and mortality INSPIRE (investigating new standards for prophylaxis in reduction of exacerbations study) [Abstract]
    • Stockley R, Calverley P, Seemungal T, Hagan G, Wedzicha J. Effect of fluticasone/salmeterol propionate versus tiotropium bromide on withdrawal rate, health status, lung function and mortality INSPIRE (investigating new standards for prophylaxis in reduction of exacerbations study) [Abstract]. European Respiratory Journal 2007;30(Suppl 51):34s [388].
    • (2007) European Respiratory Journal , vol.30 , pp. 34s [388]
    • Stockley, R.1    Calverley, P.2    Seemungal, T.3    Hagan, G.4    Wedzicha, J.5
  • 8
    • 85031426831 scopus 로고    scopus 로고
    • The INSPIRE study: effect of fluticasone/salmeterol propionate versus tiotropium bromide on COPD exacerbations [Abstract]
    • Wedzicha J, Stockley R, Seemungal T, Hagan G, Calverley P. The INSPIRE study: effect of fluticasone/salmeterol propionate versus tiotropium bromide on COPD exacerbations [Abstract]. Respirology 2007;12(Suppl 4):A112.
    • (2007) Respirology , vol.12 , pp. A112
    • Wedzicha, J.1    Stockley, R.2    Seemungal, T.3    Hagan, G.4    Calverley, P.5
  • 10
    • 85041837070 scopus 로고    scopus 로고
    • A multicentre, randomised, double-blind, double dummy, parallel group 12-week exploratory study to compare the effect of the fluticasone/salmeterol propionate combination product (SERETIDE™) 50/500mcg bd via the DISKUS™/ACCUHALER™ inhaler with tiotropium bromide 18 mcg od via the Handihaler inhalation device on efficacy and safety in patients with chronic obstructive pulmonary disease (COPD)
    • (accessed 16 June 2009)
    • GSK (SCO40034). A multicentre, randomised, double-blind, double dummy, parallel group 12-week exploratory study to compare the effect of the fluticasone/salmeterol propionate combination product (SERETIDE™) 50/500mcg bd via the DISKUS™/ACCUHALER™ inhaler with tiotropium bromide 18 mcg od via the Handihaler inhalation device on efficacy and safety in patients with chronic obstructive pulmonary disease (COPD). www.gsk-clinicalstudyregister.com/files/pdf/23678.pdf (accessed 16 June 2009).
  • 11
    • 38048999424 scopus 로고    scopus 로고
    • Comparable spirometric efficacy of tiotropium compared with salmeterol plus fluticasone in patients with COPD: a pilot study
    • Bateman ED, van Dyk M, Sagriotis A. Comparable spirometric efficacy of tiotropium compared with salmeterol plus fluticasone in patients with COPD: a pilot study. Pulmonary Pharmacology and Therapeutics 2008;21(1):20-5.
    • (2008) Pulmonary Pharmacology and Therapeutics , vol.21 , Issue.1 , pp. 20-25
    • Bateman, E.D.1    van Dyk, M.2    Sagriotis, A.3
  • 12
    • 85041506847 scopus 로고    scopus 로고
    • Addition of tiotropium (T) to a regular treatment with long-acting beta-agonist + inhaled corticosteroid (LABA + ICS) in patients with severe to very-severe COPD under in-patient pulmonary rehabilitation program (PRP) [Abstract]
    • [P526] Vienna. :
    • Biscione G, Crigna G, Auciello L, Pasqua F, Cazzola M. Addition of tiotropium (T) to a regular treatment with long-acting beta-agonist + inhaled corticosteroid (LABA + ICS) in patients with severe to very-severe COPD under in-patient pulmonary rehabilitation program (PRP) [Abstract]. European Respiratory Society Meeting, Vienna. 2009:[P526].
    • (2009) European Respiratory Society Meeting
    • Biscione, G.1    Crigna, G.2    Auciello, L.3    Pasqua, F.4    Cazzola, M.5
  • 13
    • 85041513547 scopus 로고    scopus 로고
    • Efficacy of fluticasone/salmeterol propionate 50/500mcg bd versus tiotropium on lung function and mucociliary clearance in COPD patients [Abstract]
    • Dawber F, Tandy D, Haussermann S, Betz R. Efficacy of fluticasone/salmeterol propionate 50/500mcg bd versus tiotropium on lung function and mucociliary clearance in COPD patients [Abstract]. Respirology 2005;10(Suppl 3):A99.
    • (2005) Respirology , vol.10 , pp. A99
    • Dawber, F.1    Tandy, D.2    Haussermann, S.3    Betz, R.4
  • 14
    • 85041539642 scopus 로고    scopus 로고
    • A single centre, randomised, double-blind, double dummy, parallel group 3-week study to compare the effect of the fluticasone/salmeterol propionate combination 50/500mcg bd via the DISKUS™/ACCUHALER™ inhaler with tiotropium bromide 18 mcg od via the Handihaler inhaler on mucociliary clearance rate in patients with Chronic Obstructive Pulmonary Disease (COPD)
    • (accessed 3 July 2009)
    • GSK (SCO4011). A single centre, randomised, double-blind, double dummy, parallel group 3-week study to compare the effect of the fluticasone/salmeterol propionate combination 50/500mcg bd via the DISKUS™/ACCUHALER™ inhaler with tiotropium bromide 18 mcg od via the Handihaler inhaler on mucociliary clearance rate in patients with Chronic Obstructive Pulmonary Disease (COPD). http://www.gsk-clinicalstudyregister.com/files/pdf/23676.pdf (accessed 3 July 2009).
  • 15
    • 85031401969 scopus 로고    scopus 로고
    • Effects of tiotropium and fluticasone/salmeterol combination on lung hyperinflation dyspnea and exercise tolerance in COPD [Abstract]
    • Golabi P, Topaloglu N, Karakurt S, Celikel T. Effects of tiotropium and fluticasone/salmeterol combination on lung hyperinflation dyspnea and exercise tolerance in COPD [Abstract]. European Respiratory Journal 2006;28(Suppl 50):33s [E304].
    • (2006) European Respiratory Journal , vol.28 , pp. 33s [E304]
    • Golabi, P.1    Topaloglu, N.2    Karakurt, S.3    Celikel, T.4
  • 16
    • 85041539642 scopus 로고    scopus 로고
    • A single centre, randomised, double-blind, double dummy, parallel group 3-week study to compare the effect of the fluticasone/salmeterol propionate combination 50/500mcg bd via the DISKUS™/ACCUHALER™ inhaler with tiotropium bromide 18 mcg od via the Handihaler inhaler on mucociliary clearance rate in patients with Chronic Obstructive Pulmonary Disease (COPD)
    • 2009 (accessed 4 January 2013)
    • GlaxoSmithKline. A single centre, randomised, double-blind, double dummy, parallel group 3-week study to compare the effect of the fluticasone/salmeterol propionate combination 50/500mcg bd via the DISKUS™/ACCUHALER™ inhaler with tiotropium bromide 18 mcg od via the Handihaler inhaler on mucociliary clearance rate in patients with Chronic Obstructive Pulmonary Disease (COPD). http://www.gsk-clinicalstudyregister.com 2009 (accessed 4 January 2013).
  • 18
    • 84858335279 scopus 로고    scopus 로고
    • Triple therapy of fluticasone propionate/salmeterol combination 250/50 mcg and tiotropium improves lung function compared to tiotropium monotherapy [Abstract]
    • Hanania NA, Niewoehner DE, Crater GD, Emmett A, Dell DO, Cicale Mi J. Triple therapy of fluticasone propionate/salmeterol combination 250/50 mcg and tiotropium improves lung function compared to tiotropium monotherapy [Abstract]. Chest. 2010; Vol. 138:867A.
    • (2010) Chest , vol.138 , pp. 867A
    • Hanania, N.A.1    Niewoehner, D.E.2    Crater, G.D.3    Emmett, A.4    Dell, D.O.5    Cicale Mi, J.6
  • 19
    • 85041503056 scopus 로고    scopus 로고
    • Single blind comparison of tiotropium and salmeterol plus fluticasone propionate of treatment in patients with chronic obstructive pulmonary disease (COPD) [Abstract]
    • Poster #A1 May 18-23, 2007, San Francisco, California, USA
    • Hara K, Kurashima K, Tokunaga D, Ueno M, Aoyagi K, Isobe Z, et al.Single blind comparison of tiotropium and salmeterol plus fluticasone propionate of treatment in patients with chronic obstructive pulmonary disease (COPD) [Abstract]. American Thoracic Society International Conference, May 18-23, 2007, San Francisco, California, USA 2007:Poster #A1.
    • (2007) American Thoracic Society International Conference
    • Hara, K.1    Kurashima, K.2    Tokunaga, D.3    Ueno, M.4    Aoyagi, K.5    Isobe, Z.6
  • 20
    • 79952262390 scopus 로고    scopus 로고
    • Effects of adding salmeterol/fluticasone propionate to tiotropium on airway dimensions in patients with chronic obstructive pulmonary disease
    • Hoshino M, Ohtawa J. Effects of adding salmeterol/fluticasone propionate to tiotropium on airway dimensions in patients with chronic obstructive pulmonary disease. Respirology 2011;16(1):95-101.
    • (2011) Respirology , vol.16 , Issue.1 , pp. 95-101
    • Hoshino, M.1    Ohtawa, J.2
  • 21
    • 84855906419 scopus 로고    scopus 로고
    • Comparison of tiotropium plus fluticasone propionate/salmeterol with tiotropium in COPD: A randomized controlled study
    • Jung KS, Park HY, Park SY, Kim SK, Kim YK, Shim JJ, et al.Comparison of tiotropium plus fluticasone propionate/salmeterol with tiotropium in COPD: A randomized controlled study. Respiratory Medicine 2012;106(3):382-9.
    • (2012) Respiratory Medicine , vol.106 , Issue.3 , pp. 382-389
    • Jung, K.S.1    Park, H.Y.2    Park, S.Y.3    Kim, S.K.4    Kim, Y.K.5    Shim, J.J.6
  • 22
    • 61349175228 scopus 로고    scopus 로고
    • Changes in lung function and health status in patients with COPD treated with tiotropium or salmeterol plus fluticasone
    • Kurashima K, Hara K, Yoneda K, Kanauchi T, Kagiyama N, Tokunaga D, et al.Changes in lung function and health status in patients with COPD treated with tiotropium or salmeterol plus fluticasone. Respirology 2009;14(2):239-44.
    • (2009) Respirology , vol.14 , Issue.2 , pp. 239-244
    • Kurashima, K.1    Hara, K.2    Yoneda, K.3    Kanauchi, T.4    Kagiyama, N.5    Tokunaga, D.6
  • 23
    • 85026591470 scopus 로고    scopus 로고
    • Comparison of tiotropium+salmeterol vs. fluticasone+salmeterol on lung volumes, exercise tolerance and locus of symptom limitation [Abstract]
    • Magnussen H, Maltais F, Schmidt H, Kesten S, Metzdorf N. Comparison of tiotropium+salmeterol vs. fluticasone+salmeterol on lung volumes, exercise tolerance and locus of symptom limitation [Abstract]. American Journal of Respiratory and Critical Care Medicine. 2010; Vol. 181:A4472.
    • (2010) American Journal of Respiratory and Critical Care Medicine , vol.181 , pp. A4472
    • Magnussen, H.1    Maltais, F.2    Schmidt, H.3    Kesten, S.4    Metzdorf, N.5
  • 24
    • 85041525736 scopus 로고    scopus 로고
    • Effect of fluticasone-salmeterol combination+tiotropium vs tiotropium on exercise tolerance, the cause of exercise limitation and lung volumes in COPD [Abstract]
    • Maltais F, Mahler DA, Pepin V, Nadreau E, Crater G, Morris A. Effect of fluticasone-salmeterol combination+tiotropium vs tiotropium on exercise tolerance, the cause of exercise limitation and lung volumes in COPD [Abstract]. American Journal of Respiratory and Critical Care Medicine 2012;185(1):A2267.
    • (2012) American Journal of Respiratory and Critical Care Medicine , vol.185 , Issue.1 , pp. A2267
    • Maltais, F.1    Mahler, D.A.2    Pepin, V.3    Nadreau, E.4    Crater, G.5    Morris, A.6
  • 25
    • 79955053637 scopus 로고    scopus 로고
    • Cost effectiveness of budesonide/formoterol added to tiotropium bromide versus placebo added to tiotropium bromide in patients with chronic obstructive pulmonary disease: Australian, Canadian and Swedish healthcare perspectives
    • Mittmann N, Hernandez P, Mellstrom C, Brannman L, Welte T. Cost effectiveness of budesonide/formoterol added to tiotropium bromide versus placebo added to tiotropium bromide in patients with chronic obstructive pulmonary disease: Australian, Canadian and Swedish healthcare perspectives. Pharmacoeconomics 2011;29(5):403-14.
    • (2011) Pharmacoeconomics , vol.29 , Issue.5 , pp. 403-414
    • Mittmann, N.1    Hernandez, P.2    Mellstrom, C.3    Brannman, L.4    Welte, T.5
  • 26
    • 85031423278 scopus 로고    scopus 로고
    • Cost-effectiveness of budesonide/formoterol added to tiotropium in COPD patients in Canada, Australia and Sweden [Abstract]
    • [5183] Barcelona, Spain, September 18-22. :
    • Mittmann N, Hernandez P, Mellström C, Brannman L, Welte T, Mellström C, et al.Cost-effectiveness of budesonide/formoterol added to tiotropium in COPD patients in Canada, Australia and Sweden [Abstract]. European Respiratory Society Annual Congress, Barcelona, Spain, September 18-22. 2010:[5183].
    • (2010) European Respiratory Society Annual Congress
    • Mittmann, N.1    Hernandez, P.2    Mellström, C.3    Brannman, L.4    Welte, T.5    Mellström, C.6
  • 27
    • 85041522511 scopus 로고    scopus 로고
    • A randomized, open label, multicenter, phase 4 study for the comparison of efficacy of tiotropium plus salmeterol/ fluticasone propionate compared with tiotropium alone in COPD patients
    • NCT00864812. A randomized, open label, multicenter, phase 4 study for the comparison of efficacy of tiotropium plus salmeterol/ fluticasone propionate compared with tiotropium alone in COPD patients. http://clinicaltrials.gov/show/NCT00864812 2009.
    • (2009)
  • 28
    • 85041548039 scopus 로고    scopus 로고
    • A study of fluticasone propionate/salmeterol DISKUS combination product 250/50 mcg twice daily plus tiotropium 18 mcg daily versus placebo DISKUS twice daily plus tiotropium 18 mcg daily on exercise time and physiological parameters in subjects with chronic obstructive pulmonary disease
    • NCT01124422. A study of fluticasone propionate/salmeterol DISKUS combination product 250/50 mcg twice daily plus tiotropium 18 mcg daily versus placebo DISKUS twice daily plus tiotropium 18 mcg daily on exercise time and physiological parameters in subjects with chronic obstructive pulmonary disease. http://clinicaltrials.gov/show/NCT01124422 2010.
    • (2010)
  • 29
    • 85041514146 scopus 로고    scopus 로고
    • A randomised, parallel-group, open-label, multicentre, 3-month phase IV, efficacy and tolerability study of budesonide/formoterol (Symbicort® Turbuhaler® 160/4.5 μg/inhalation, 2 inhalations twice daily) added to tiotropium (SpirivaTM 18 μg/inhalation, 1 inhalation once daily) compared with tiotropium (SpirivaTM 18 μg/inhalation, 1 inhalation once daily) alone in severe chronic obstructive pulmonary disease (COPD) patients
    • NCT01397890. A randomised, parallel-group, open-label, multicentre, 3-month phase IV, efficacy and tolerability study of budesonide/formoterol (Symbicort® Turbuhaler® 160/4.5 μg/inhalation, 2 inhalations twice daily) added to tiotropium (SpirivaTM 18 μg/inhalation, 1 inhalation once daily) compared with tiotropium (SpirivaTM 18 μg/inhalation, 1 inhalation once daily) alone in severe chronic obstructive pulmonary disease (COPD) patients. http://clinicaltrials.gov/show/NCT01397890 2011.
    • (2011)
  • 31
    • 42149166529 scopus 로고    scopus 로고
    • Superiority of "triple" therapy with fluticasone/salmeterol propionate and tiotropium bromide versus individual components in moderate to severe COPD
    • Singh D, Brooks J, Hagan G, Cahn A, O'Connor BJ. Superiority of "triple" therapy with fluticasone/salmeterol propionate and tiotropium bromide versus individual components in moderate to severe COPD. Thorax 2008;63(7):592-8.
    • (2008) Thorax , vol.63 , Issue.7 , pp. 592-598
    • Singh, D.1    Brooks, J.2    Hagan, G.3    Cahn, A.4    O'Connor, B.J.5
  • 32
    • 84865160348 scopus 로고    scopus 로고
    • Computed tomography assessment of pharmacological lung volume reduction induced by bronchodilators in COPD
    • Tanabe N, Muro S, Oguma T, Sato S, Kiyokawa H, Takahashi T, et al.Computed tomography assessment of pharmacological lung volume reduction induced by bronchodilators in COPD. COPD 2012;9:401-8.
    • (2012) COPD , vol.9 , pp. 401-408
    • Tanabe, N.1    Muro, S.2    Oguma, T.3    Sato, S.4    Kiyokawa, H.5    Takahashi, T.6
  • 34
    • 85031400281 scopus 로고    scopus 로고
    • Addition of budesonide/formoterol to tiotropium reduces the number of exacerbation days compared with tiotropium alone [Abstract]
    • Welte T, Miravitlles M, Hernandez P, Eriksson G, Peterson S, Polanowski T, et al.Addition of budesonide/formoterol to tiotropium reduces the number of exacerbation days compared with tiotropium alone [Abstract]. Chest 2009;136(4):26S-f.
    • (2009) Chest , vol.136 , Issue.4 , pp. 26S-26f
    • Welte, T.1    Miravitlles, M.2    Hernandez, P.3    Eriksson, G.4    Peterson, S.5    Polanowski, T.6
  • 35
    • 85031398397 scopus 로고    scopus 로고
    • Budesonide/formoterol added to tiotropium provides rapid improvements in lung function and ability to undertake morning activities [Abstract]
    • Welte T, Miravitlles M, Hernandez P, Eriksson G, Peterson S, Polanowski T, et al.Budesonide/formoterol added to tiotropium provides rapid improvements in lung function and ability to undertake morning activities [Abstract]. Chest 2009; Vol. 136, issue 4:24S-g.
    • (2009) Chest , vol.136 , Issue.4 , pp. 24S-24g
    • Welte, T.1    Miravitlles, M.2    Hernandez, P.3    Eriksson, G.4    Peterson, S.5    Polanowski, T.6
  • 37
    • 85031414202 scopus 로고    scopus 로고
    • Budesonide/formoterol added to tiotropium improves exacerbations and exacerbation-related antibiotic use in patients with COPD [Abstract]
    • Welte T, Miravitlles M, Hernandez P, Peterson S, Polanowski T, Kessler R, et al.Budesonide/formoterol added to tiotropium improves exacerbations and exacerbation-related antibiotic use in patients with COPD [Abstract]. European Respiratory Society. 2009:[P2012].
    • (2009) European Respiratory Society , pp. [P2012]
    • Welte, T.1    Miravitlles, M.2    Hernandez, P.3    Peterson, S.4    Polanowski, T.5    Kessler, R.6
  • 38
    • 77956844290 scopus 로고    scopus 로고
    • Paradoxical trough effects of triple therapy with budesonide/formoterol and tiotropium bromide on pulmonary function outcomes in COPD
    • Williamson PA, Short PM, Clearie KL, Vaidyanathan S, Fardon TC, Howaniec LJ, et al.Paradoxical trough effects of triple therapy with budesonide/formoterol and tiotropium bromide on pulmonary function outcomes in COPD. Chest 2010;138(3):595-604.
    • (2010) Chest , vol.138 , Issue.3 , pp. 595-604
    • Williamson, P.A.1    Short, P.M.2    Clearie, K.L.3    Vaidyanathan, S.4    Fardon, T.C.5    Howaniec, L.J.6
  • 39
    • 85041548108 scopus 로고    scopus 로고
    • A multicenter, randomized, blinded, active-controlled, parallel-group study to compare the efficacy, tolerability and safety of NVA237 compared to tiotropium added on to fluticasone/salmeterol in patients with chronic obstructive pulmonary disease
    • NCT01513460. A multicenter, randomized, blinded, active-controlled, parallel-group study to compare the efficacy, tolerability and safety of NVA237 compared to tiotropium added on to fluticasone/salmeterol in patients with chronic obstructive pulmonary disease. http://clinicaltrials.gov/show/NCT01513460 2012.
    • (2012)
  • 45
    • 84872336831 scopus 로고    scopus 로고
    • Tiotropium versus long-acting beta-agonists for stable chronic obstructive pulmonary disease
    • Chong J, Karner C, Poole P. Tiotropium versus long-acting beta-agonists for stable chronic obstructive pulmonary disease. Cochrane Database of Systematic Reviews 2012, Issue 9. [DOI: 10.1002/14651858.CD009157.pub2].
    • (2012) Cochrane Database of Systematic Reviews , Issue.9
    • Chong, J.1    Karner, C.2    Poole, P.3
  • 46
    • 84887346660 scopus 로고    scopus 로고
    • Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.1 [updated September 2008]
    • (accessed 26 February 2009)
    • Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.0.1 [updated September 2008]. The Cochrane Collaboration, 2008. Available from www.cochrane-handbook.org (accessed 26 February 2009).
    • (2008) The Cochrane Collaboration
    • Higgins, J.P.T.1    Green, S.2
  • 48
    • 84943656481 scopus 로고    scopus 로고
    • Global Initiative for Chronic Obstructive Lung Disease
    • accessed 18 February 2009
    • Global Initiative for Chronic Obstructive Lung Disease. http://www.goldcopd.com (accessed 18 February 2009).
  • 49
    • 1642407902 scopus 로고
    • Clinical safety data management: Definitions and standards for expedited reporting
    • Expert Working Group (Efficacy) of the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH). Clinical safety data management: Definitions and standards for expedited reporting. http://www.fda.gov/cder/guidance/iche2a.pdf 1995.
    • (1995)
  • 50
    • 70349883780 scopus 로고    scopus 로고
    • Triple therapy for chronic obstructive pulmonary disease: trials catching up with clinical practice?
    • Jones PW. Triple therapy for chronic obstructive pulmonary disease: trials catching up with clinical practice?. American Journal of Respiratory and Critical Care Medicine 2009;180(8):689-90.
    • (2009) American Journal of Respiratory and Critical Care Medicine , vol.180 , Issue.8 , pp. 689-690
    • Jones, P.W.1
  • 51
    • 79953283384 scopus 로고    scopus 로고
    • Combination inhaled steroid and long-acting beta2-agonist in addition to tiotropium versus tiotropium or combination alone for chronic obstructive pulmonary disease
    • Karner C, Cates CJ. Combination inhaled steroid and long-acting beta2-agonist in addition to tiotropium versus tiotropium or combination alone for chronic obstructive pulmonary disease. Cochrane Database of Systematic Reviews 2011, Issue 3. [DOI: 10.1002/14651858.CD008532.pub2].
    • (2011) Cochrane Database of Systematic Reviews , Issue.3
    • Karner, C.1    Cates, C.J.2
  • 52
    • 80055073224 scopus 로고    scopus 로고
    • The effect of adding inhaled corticosteroids to tiotropium and long-acting beta2-agonists for chronic obstructive pulmonary disease
    • Karner C, Cates CJ. The effect of adding inhaled corticosteroids to tiotropium and long-acting beta2-agonists for chronic obstructive pulmonary disease. Cochrane Database of Systematic Reviews 2011, Issue 9. [DOI: 10.1002/14651858.CD009039.pub2].
    • (2011) Cochrane Database of Systematic Reviews , Issue.9
    • Karner, C.1    Cates, C.J.2
  • 53
    • 84863841937 scopus 로고    scopus 로고
    • Long-acting beta2-agonist in addition to tiotropium versus either tiotropium or long-acting beta2-agonist alone for chronic obstructive pulmonary disease
    • Karner C, Cates CJ. Long-acting beta2-agonist in addition to tiotropium versus either tiotropium or long-acting beta2-agonist alone for chronic obstructive pulmonary disease. Cochrane Database of Systematic Reviews 2012, Issue 4. [DOI: 10.1002/14651858.CD008989.pub2].
    • (2012) Cochrane Database of Systematic Reviews , Issue.4
    • Karner, C.1    Cates, C.J.2
  • 54
    • 84866439937 scopus 로고    scopus 로고
    • Tiotropium versus placebo for chronic obstructive pulmonary disease
    • Karner C, Chong J, Poole P. Tiotropium versus placebo for chronic obstructive pulmonary disease. Cochrane Database of Systematic Reviews 2012, Issue 7. [DOI: 10.1002/14651858.CD009285.pub2].
    • (2012) Cochrane Database of Systematic Reviews , Issue.7
    • Karner, C.1    Chong, J.2    Poole, P.3
  • 58
    • 40949119305 scopus 로고    scopus 로고
    • Combined corticosteroid and long-acting beta2-agonist in one inhaler versus placebo for chronic obstructive pulmonary disease
    • Nannini LJ, Cates CJ, Lasserson TJ, Poole P. Combined corticosteroid and long-acting beta2-agonist in one inhaler versus placebo for chronic obstructive pulmonary disease. Cochrane Database of Systematic Reviews 2007, Issue 4. [DOI: 10.1002/14651858.CD003794.pub3].
    • (2007) Cochrane Database of Systematic Reviews , Issue.4
    • Nannini, L.J.1    Cates, C.J.2    Lasserson, T.J.3    Poole, P.4
  • 59
    • 38449087450 scopus 로고    scopus 로고
    • Combined corticosteroid and long-acting beta2-agonist in one inhaler versus inhaled steroids for chronic obstructive pulmonary disease
    • Nannini LJ, Cates CJ, Lasserson TJ, Poole P. Combined corticosteroid and long-acting beta2-agonist in one inhaler versus inhaled steroids for chronic obstructive pulmonary disease. Cochrane Database of Systematic Reviews 2007, Issue 4. [DOI: 10.1002/14651858.CD006826].
    • (2007) Cochrane Database of Systematic Reviews , Issue.4
    • Nannini, L.J.1    Cates, C.J.2    Lasserson, T.J.3    Poole, P.4
  • 60
    • 84870598137 scopus 로고    scopus 로고
    • Combined corticosteroid and long-acting beta2-agonist in one inhaler versus long-acting beta2-agonists for chronic obstructive pulmonary disease
    • Nannini LJ, Lasserson TJ, Poole P. Combined corticosteroid and long-acting beta2-agonist in one inhaler versus long-acting beta2-agonists for chronic obstructive pulmonary disease. Cochrane Database of Systematic Reviews 2012, Issue 9. [DOI: 10.1002/14651858.CD006829.pub2].
    • (2012) Cochrane Database of Systematic Reviews , Issue.9
    • Nannini, L.J.1    Lasserson, T.J.2    Poole, P.3
  • 61
    • 79960705415 scopus 로고    scopus 로고
    • Review Manager (RevMan)
    • 5.2. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration
    • The Nordic Cochrane Centre, The Cochrane Collaboration. Review Manager (RevMan). 5.2. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2012.
    • (2012)
  • 62
    • 2142853566 scopus 로고    scopus 로고
    • St George Respiratory Questionnaire
    • accessed 6 October 2009
    • Jones P. St George Respiratory Questionnaire. http://www.healthstatus.sgul.ac.uk/downloads/respiratory_questionairre.htm (accessed 6 October 2009).
    • Jones, P.1
  • 63
    • 52449106502 scopus 로고    scopus 로고
    • Inhaled anticholinergics and risk of major adverse cardiovascular events in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis
    • Singh S, Loke YK, Furberg CD. Inhaled anticholinergics and risk of major adverse cardiovascular events in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis. JAMA 2008;300(12):1439-50.
    • (2008) JAMA , vol.300 , Issue.12 , pp. 1439-1450
    • Singh, S.1    Loke, Y.K.2    Furberg, C.D.3
  • 64
    • 60549089385 scopus 로고    scopus 로고
    • Long-term use of inhaled corticosteroids and the risk of pneumonia in chronic obstructive pulmonary disease
    • Singh S, Amin AV, Loke YK. Long-term use of inhaled corticosteroids and the risk of pneumonia in chronic obstructive pulmonary disease. Archives of Internal Medicine 2009;169(3):219-29.
    • (2009) Archives of Internal Medicine , vol.169 , Issue.3 , pp. 219-229
    • Singh, S.1    Amin, A.V.2    Loke, Y.K.3
  • 65
    • 80155128923 scopus 로고    scopus 로고
    • Inhaled corticosteroids versus long-acting beta2-agonists for chronic obstructive pulmonary disease
    • Spencer S, Karner C, Cates CJ, Evans DJ. Inhaled corticosteroids versus long-acting beta2-agonists for chronic obstructive pulmonary disease. Cochrane Database of Systematic Reviews 2011, Issue 12. [DOI: 10.1002/14651858.CD007033.pub3].
    • (2011) Cochrane Database of Systematic Reviews , Issue.12
    • Spencer, S.1    Karner, C.2    Cates, C.J.3    Evans, D.J.4
  • 68
    • 33847172367 scopus 로고    scopus 로고
    • Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease
    • 1533-4406: (Electronic)]
    • Calverley PM, Anderson JA, Celli B, Ferguson GT, Jenkins C, Jones PW, et al.Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease. New England Journal of Medicine 2007;356(8):775-89. [1533-4406: (Electronic)].
    • (2007) New England Journal of Medicine , vol.356 , Issue.8 , pp. 775-789
    • Calverley, P.M.1    Anderson, J.A.2    Celli, B.3    Ferguson, G.T.4    Jenkins, C.5    Jones, P.W.6


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