Nebulised hypertonic saline solution for acute bronchiolitis in infants (Review)

Cochrane Database of Systematic Reviews

Volumn 2013, Issue 7, 2013, Pages

  Zhang, Linjie ^a   Mendoza Sassi, Raúl A ^a   Wainwright, Claire ^b   Klassen, Terry P ^c  

^a FEDERAL UNIVERSITY OF RIO GRANDE   (Brazil)

^b ROYAL CHILDREN'S HOSPITAL   (Australia)

^c MANITOBA INSTITUTE OF CHILD HEALTH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

EPINEPHRINE; SALBUTAMOL; SODIUM CHLORIDE; TERBUTALINE; BRONCHODILATING AGENT;

DISEASE SEVERITY; DRUG EFFECT; EMERGENCY WARD; HOSPITAL PATIENT; HOSPITAL READMISSION; HOSPITALIZATION; HUMAN; LENGTH OF STAY; META ANALYSIS; NEBULIZATION; OUTPATIENT; OXYGEN SATURATION; PRIORITY JOURNAL; REVIEW; SYSTEMATIC REVIEW; TREATMENT OUTCOME; UNSPECIFIED SIDE EFFECT; VIRAL BRONCHIOLITIS; ACUTE DISEASE; BRONCHIOLITIS, VIRAL; INFANT; NEBULIZER; RANDOMIZED CONTROLLED TRIAL (TOPIC);

ACUTE DISEASE; BRONCHIOLITIS, VIRAL; BRONCHODILATOR AGENTS; HUMANS; INFANT; NEBULIZERS AND VAPORIZERS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; SALINE SOLUTION, HYPERTONIC;

EID: 84891652802     PISSN: None     EISSN: 1469493X     Source Type: Journal    
DOI: 10.1002/14651858.CD006458.pub3     Document Type: Review

References (55)

1. Al-Ansari K, Sakran M, Davidson BL, Sayyed RE, Mahjoub H, Ibrahim K. Nebulized 5% or 3% hypertonic or 0.9% saline for treating acute bronchiolitis in infants. Journal of Pediatrics 2010;157:630-4.
2. Anil AB, Anil M, Saglam AB, Cetin N, Bal A, Aksu N. High volume normal saline alone is as effective as nebulized salbutamol-normal saline, epinephrine-normal saline, and 3% saline in mild bronchiolitis. Pediatric Pulmonology 2010;45(1):41-7.
3. Del Giudice MM, Saitta F, Leonardi S, Capasso M, Niglio B, Chinellato I, et al. Effectiveness of nebulized hypertonic saline and epinephrine in hospitalized infants with bronchiolitis. International Journal of Immunopathology and Pharmacology 2012;25(2):485-91.
4. Grewal S, Ali S, McConnell DW, Vandermeer B, Klassen TP. A randomized trial of nebulized 3% hypertonic saline with epinephrine in the treatment of acute bronchiolitis in the emergency department. Archives of Pediatrics & Adolescent Medicine 2009;163(11):1007-12.
5. Ipek IO, Yalcin EU, Sezer RG, Bozaykut A. The efficacy of nebulized salbutamol, hypertonic saline and salbutamol/hypertonic saline combination in moderate bronchiolitis. Pulmonary Pharmacology & Therapeutics 2011;24:633-7.
6. Kuzik BA, Al Qaghi SA, Kent S, Flavin MP, Hopman W, Hotte S, et al. Nebulized hypertonic saline in the treatment of viral bronchiolitis in infants. Journal of Pediatrics 2007;151:266-70.
7. Luo Z, Liu E, Luo J, Li S, Zeng F, Yang X, et al. Nebulized hypertonic saline/salbutamol solution treatment in hospitalized children with mild to moderate bronchiolitis. Pediatrics International 2010;52:199-202.
8. Luo Z, Fu Z, Liu E, Xu X, Fu X, Peng D, et al. Nebulized hypertonic saline treatment in hospitalized children with moderate to severe viral bronchiolitis. Clinical Microbiology and Infection 2011;17:1829-33.
9. Mandelberg A, Tal G, Witzling M, Someck E, Houri S, Balin A, et al. Nebulized 3% hypertonic saline solution treatment in hospitalized infants with viral bronchiolitis. Chest 2003;123:481-7.
10. Sarrell EM, Tal G, Witzling M, Someck E, Houri S, Cohen HA, et al. Nebulized 3% hypertonic saline solution treatment in ambulatory children with viral bronchiolitis decreases symptoms. Chest 2002;122:2015-20.
11. Tal G, Cesar K, Oron A, Houri S, Ballin A, Mandelberg A. Hypertonic saline/epinephrine treatment in hospitalized infants with viral bronchiolitis reduces hospitalization stay: 2 years experience. Israel Medical Association Journal 2006;8:169-73.
12. Amirav I, Oron A, Tal G, Cesar K, Ballin A, Houri S, et al. Aerosol delivery in RSV bronchiolitis: hood or face-mask?. Journal of Pediatrics 2005;147(5):627-31.
13. Guomo R, Cossettini M, Saretta F, Fasoli L, Guerrera T, Canciani M. Efficacy of hypertonic saline solution in infants with acute bronchiolitis. European Respiratory Journal 2007;30(Suppl):51, E3016.
14. Kuzik BA, Flavin MP, Kent S, Zielinski D, Kwan CW, Adeleye A, et al. Effect of inhaled hypertonic saline on hospital admission rate in children with viral bronchiolitis: a randomized trial. Canadian Journal of Emergency Medicine 2010;12(6):477-84.
15. Tribastone AD. Nebulized 3% saline effective for viral bronchiolitis. Journal of Family Practice 2003;52(5):359-60.
16. Assouline G, Leibson V, Danon A. Stimulation of prostaglandin output from rat stomach by hypertonic solution. European Journal of Pharmacology 1977;44:271-3.
17. Bertrand P, Aranibar H, Castro E, Sanchez I. Efficacy of nebulized epinephrine versus salbutamol in hospitalized infants with bronchiolitis. Pediatric Pulmonology 2001;31(4):284-8.
18. Daviskas E, Anderson SD, Gonda I, Eberl S, Meikle S, Seale JP, et al. Inhalation of hypertonic saline aerosol enhances mucociliary clearance in asthmatic and healthy subjects. European Respiratory Journal 1996;9(4):725-32.
19. Dickersin K, Scherer R, Lefebvre C. Identifying relevant studies for systematic reviews. BMJ 1994;309:1286-91.
20. Enriquez A, Chu I-W, Mellis C, Lin W-Y Nebulised deoxyribonuclease for viral bronchiolitis in children younger than 24 months. Cochrane Database of Systematic Reviews 2012, Issue 11. [DOI: 10.1002/14651858.CD008395.pub2]
21. Garcia-Garcia ML, Calvo C, Perez-Brena P, De Cea JM, Acosta B, Casas I. Prevalence and clinical characteristics of human metapneumovirus infections in hospitalized infants in Spain. Pediatric Pulmonology 2006;41(9):863-71.
22. Hartling L, Bialy LM, Vandermeer B, Tjosvold L, Johnson DW, Plint AC, et al. Epinephrine for bronchiolitis. Cochrane Database of Systematic Reviews 2011, Issue 6. [DOI: 10.1002/14651858.CD003123.pub3]
23. Henderson FW, Clyde WA Jr, Collier AM, Denny FW, Senior RJ, Sheaffer CI, et al. The etiologic and epidemiologic spectrum of bronchiolitis in pediatric practice. Journal of Pediatrics 1979;95:183-90.
24. Higgins JPT, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analysis. BMJ 2003;327:557-60.
25. Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
26. Jacques J, Bouscambert-Duchamp M, Moret H, Carquin J, Brodard V, Lina B, et al. Association of respiratory picornaviruses with acute bronchiolitis in French infants. Journal of Clinical Virology 2006;25(4):463-6.
27. Kellett F, Redfern J, Niven RM. Evaluation of nebulised hypertonic saline (7%) as an adjunct to physiotherapy in patients with stable bronchiectasis. Respiratory Medicine 2005;99(1):27-31.
28. Klassen TP. Recent advances in the treatment of bronchiolitis and laryngitis. Pediatric Clinics of North America 1997;44(1):249-61.
29. Klassen TP, Sutcliffe T, Watters LK, Wells GA, Allen UD, Li MM. Dexamethasone in salbutamol-treated in patients with acute bronchiolitis: a randomized, controlled trial. Journal of Pediatrics 1997;130:191-6.
30. Langley JM, LeBlanc JC, Smith B, Wang EEL. Increasing incidence of hospitalization for bronchiolitis among Canadian children, 1980-2000. Journal of Infectious Diseases 2003;188:1764-7.
31. Lowell DI, Lister G, Von Kloss H, McCarthy P. Wheezing in infants: the response to epinephrine. Pediatrics 1987;87:939-45.
32. Mandelberg A, Amirav I. Hypertonic saline or high volume normal saline for viral bronchiolitis: Mechanisms and rationale. Pediatric Pulmonology 2010;45:36-40.
33. Meissner HC. Selected populations at increased risk from respiratory syncytial virus infection. Pediatric Infectious Disease Journal 2003;22(Suppl 2):40-4.
34. Nasr SZ, Strouse PJ, Soskoline E, Maxvold NJ, Garver KA, Rubin BK, et al. Efficacy of recombinant human deoxyribonuclease I in the hospital management of respiratory syncytial virus bronchiolitis. Chest 2001;120(1):203-8.
35. Njoo H, Pelletier L, Spika L. Respiratory disease in Canada. Ottawa: Canadian Institute for Health Information, Health Canada and Statistics Canada 2001:65-87.
36. Panitch HB, Callahan CW, Schidlow DV. Bronchiolitis in children. Clinics in Chest Medicine 1993;14(4):715-31.
37. Panitch HB. Respiratory syncytial virus bronchiolitis: supportive care and therapies designed to overcome airway obstruction. Pediatric Infectious Disease Journal 2003;22(Suppl):83-8.
38. Rakshi K, Couriel JM. Management of acute bronchiolitis. Archives of Disease in Childhood 1994;71(5):463-9.
39. The Nordic Cochrane Centre, The Cochrane Collaboration. Review Manager (RevMan). 5.2. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2012.
40. Robinson M, Hemming A, Regnis J, Wong A, Bailey D, Bautotvich GJ, et al. Effect of increasing doses of hypertonic saline on mucociliary clearance in patients with cystic fibrosis. Thorax 1997;52(10):900-3.
41. Roqué i Figuls M, Giné-Garriga M, Granados Rugeles C, Perrotta C. Chest physiotherapy for acute bronchiolitis in paediatric patients between 0 and 24 months old. Cochrane Database of Systematic Reviews 2012, Issue 2. [DOI: 10.1002/14651858.CD004873.pub4]
42. Rose RM, Pinkston P, O'Donnell C, Jensen WA. Viral infection of the lower respiratory tract. Clinical Chest Medicine 1987;8:405-18.
43. Schuh S, Johnson D, Canny G, Reisman J, Shields M, Kovesi T, et al. Efficacy of adding nebulized ipratropium bromide to nebulized albuterol therapy in acute bronchiolitis. Pediatrics 1992;90:920-3.
44. Shay DK, Holman RC, Newman RD, Liu LL, Stout JW, Anderson LJ. Bronchiolitis hospitalizations. JAMA 1999;282(15):1440-6.
45. Shay DK, Holman RC, Roosevelt GE, Clarke MJ, Anderson LJ. Bronchiolitis-associated mortality and estimates of respiratory syncytial virus-associated deaths among US children 1979-1997. Journal of Infectious Diseases 2001;183:16-22.
46. Shoseyov D, Bibi H, Shai P, Ahoseyov N, Shazberg G, Hurvitz H. Treatment with hypertonic saline versus normal saline nasal wash of pediatric chronic sinusitis. Journal of Allergy and Clinical Immunology 1998;101(5):602-5.
47. Wainwright C, Altamirano L, Cheney M, Cheney J, Barber S, Price D, et al. A multicenter, randomized, double-blind, controlled trial of nebulized epinephrine in infants with acute bronchiolitis. New England Journal of Medicine 2003;349:27-35.
48. Wang EE, Milner RA, Navas L, Maj H. Observer agreement for respiratory signs and oximetry in infants hospitalized with lower respiratory infections. American Review of Respiratory Diseases 1992;145(1):106-9.
49. Wark PAB, McDonald V. Nebulised hypertonic saline for cystic fibrosis. Cochrane Database of Systematic Reviews 2009, Issue 2. [DOI: 10.1002/14651858.CD001506.pub2]
50. Wohl MEB, Chernick V. State of the art: bronchiolitis. American Review of Respiratory Diseases 1978;118:759-81.
51. Wohl ME, Chernick VC. Treatment of acute bronchiolitis. New England Journal of Medicine 2003;349:82-3.
52. Zhang L, Ferruzzi E, Bonfanti T, Auler MI, Davila NE, Faria CS, et al. Long and short-term effect of prednisolone in hospitalized infants with acute bronchiolitis. Journal of Paediatrics and Child Health 2003;39:548-51.
53. Ziment I. Respiratory Pharmacology and Therapeutics. Philadelphia: WB Saunders, 1978.
54. Zhang L, Mendoza-Sassi RA, Wainwright C, Klassen TP. Nebulized hypertonic saline solution for acute bronchiolitis in infants. Cochrane Database of Systematic Reviews 2008, Issue 4. [DOI: 10.1002/14651858.CD006458.pub2]
55. Zhang L, Mendoza-Sassi RA, Wainwright C, Klassen TP. Nebulized hypertonic saline solution for acute bronchiolitis in infants. Cochrane Database of Systematic Reviews 2011, Issue 3. [DOI: 10.1002/14651858.CD006458.pub2]