The effectiveness of hyaluronic acid intra-articular injections in managing osteoarthritic knee pain

Annals of the Royal College of Surgeons of England

Volumn 95, Issue 8, 2013, Pages 545-551

  Trigkilidas, Dionysios ^a   Anand, A ^a  

^a UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

Hyaluronic acid; Knee; Osteoarthritis

Indexed keywords

HYALURONIC ACID; VISCOSUPPLEMENT;

EPIDEMIOLOGY; HUMAN; INTRAARTICULAR DRUG ADMINISTRATION; MUSCULOSKELETAL PAIN; OSTEOARTHRITIS, KNEE; PAIN MEASUREMENT; TREATMENT OUTCOME;

EPIDEMIOLOGIC METHODS; HUMANS; HYALURONIC ACID; INJECTIONS, INTRA-ARTICULAR; MUSCULOSKELETAL PAIN; OSTEOARTHRITIS, KNEE; PAIN MEASUREMENT; TREATMENT OUTCOME; VISCOSUPPLEMENTS;

EID: 84891652250     PISSN: 00358843     EISSN: None     Source Type: Journal    
DOI: 10.1308/rcsann.2013.95.8.545     Document Type: Article

References (28)

1. Osteoarthritis. Centres for Disease Control and Prevention. http://www.cdc.gov/arthritis/basics/osteoarthritis.htm (cited August 2013).
2. NIH Consensus Statement on total knee replacement. NIH Consens State Sci Statements 2003; 20: 1-34.
3. Balazs EA, Denlinger JL. Viscosupplementation: a new concept in the treatment of osteoarthritis. J Rheumatol Suppl 1993; 39: 3-9.
4. Altman RD, Akermark C, Beaulieu AD, Schnitzer T. Efficacy and safety of a single intra-articular injection of non-animal stabilized hyaluronic acid (NASHA) in patients with osteoarthritis of the knee. Osteoarthritis Cartilage 2004; 12: 642-649.
5. Larsen NE, Lombard KM, Parent EG, Balazs EA. Effect of hyalan on cartilage and chondrocyte cultures. J Orthop Res 1992; 10: 23-32.
6. Ghosh P. The role of hyaluronic acid (hyaluronan) in health and disease: interactions with cells, cartilage and components of synovial fluid. Clin Exp Rheumatol 1994; 12: 75-82.
7. Dahl LB, Dhal IM, Engström-Laurent A, Granath K. Concentration and molecular weight of sodium hyaluronate in synovial fluid from patients with rheumatoid arthritis and other arthropathies. Ann Rheum Dis 1985; 44: 817-822.
8. Belcher C, Yaqup R, Fawtrop F et al. Synovial fluid chondroitin and keratan sulphate epitopes, glycoaminoglycans, and hyaluronan in arthritic and normal knees. Ann Rheum Dis 1997; 56: 299-307.
9. Bellamy N, Campbell J, Robinson V et al. Viscosupplementation for the treatment of osteoarthritis of the knee. Cochrane Database Syst Rev 2006; 2: CD005321.
10. Kul-Panza E, Berker N. Is hyaluronate sodium effective in the management of knee osteoarthritis? A placebo-controlled double-blind study. Minerva Med 2010; 101: 63-72.
11. Jørgensen A, Stengaard-Pedersen K, Simonsen O et al. Intra-articular hyaluronan is without clinical effect in knee osteoarthritis: a multicentre, randomised, placebo-controlled, double-blind study of 337 patients followed for 1 year. Ann Rheum Dis 2010; 69: 1,097-1,102.
12. Leopold SS, Redd BB, Warme WJ et al. Corticosteroid compared with hyaluronic acid injections for the treatment of osteoarthritis of the knee. A prospective, randomized trial. J Bone Joint Surg Am 2003; 85: 1,197-1,203.
13. Tasciotaoglu F, Oner C. Efficacy of intra-articular sodium hyaluronate in the treatment of knee osteoarthritis. Clin Rheumatol 2003; 22: 112-117.
14. Guyatt GH, Sackett DL, Cook DJ. Users' guides to the medical literature. II. How to use an article about therapy or prevention. A. Are the results of the study valid? JAMA 1993; 270: 2,598-2,601.
15. Guyatt GH, Sackett DL, Cook DJ. Users' guides to the medical literature. II. How to use an article about therapy or prevention. B. What were the results and will they help me in caring for my patients? JAMA 1993; 271: 59-63.
16. Oxman AD, Cook DJ, Guyatt GH. Users' guides to the medical literature. VI. How to use an overview. JAMA 1994; 272: 1,367-1,371.
17. Dougados M, Nguyen M, Listrat V, Amor B. High molecular weight sodium hyaluronate (hyalectin) in osteoarthritis of the knee: a 1 year placebo-controlled trial. Osteoarthritis Cartilage 1993; 1: 97-103.
18. Henderson EB, Smith EC, Pegley F, Blake DR. Intra-articular injections of 750 kD hyaluronan in the treatment of osteoarthritis: a randomised single centre double-blind placebo-controlled trial of 91 patients demonstrating lack of efficacy. Ann Rheum Dis 1994; 53: 529-534.
19. Jones AC, Pattrick M, Doherty S, Doherty M. Intra-articular hyaluronic acid compared to intra-articular triamcinolone hexacetonide in inflammatory knee osteoarthritis. Osteoarthritis Cartilage 1995; 3: 269-273.
20. Lohmander LS, Dalén N, Englund G et al. Intra-articular hyaluronan injections in the treatment of osteoarthritis of the knee: a randomised, double blind, placebo controlled multicentre trial. Ann Rheum Dis 1996; 55: 424-431.
21. Wu JJ, Shih LY, Hsu HC, Chen TH. The double-blind test of sodium hyaluronate (ARTZ) on osteoarthritis knee. Zhonghua Yi Xue Za Zhi 1997; 59: 99-106.
22. Wobig M, Dickhut A, Maier R, Vetter G. Viscosupplementation with hylan G-F 20: a 26-week controlled trial of efficacy and safety in the osteoarthritic knee. Clin Ther 1998; 20: 410-423.
23. Huskisson EC, Donnelly S. Hyaluronic acid in the treatment of osteoarthritis of the knee. Rheumatology 1999; 38: 602-607.
24. Day R, Brooks P, Conaghan PG, Petersen M. A double blind, randomized, multicenter, parallel group study of the effectiveness and tolerance of intraarticular hyaluronan in osteoarthritis of the knee. J Rheumatol 2004; 31: 775-782.
25. Neustadt D, Caldwell J, Bell M et al. Clinical effects of intraarticular injection of high molecular weight hyaluronan (Orthovisc) in osteoarthritis of the knee: a randomized, controlled, multicenter trial. J Rheumatol 2005; 32: 1,928-1,936.
26. Petrella RJ, Petrella M. A prospective, randomized, double-blind, placebo controlled study to evaluate the efficacy of intraarticular hyaluronic acid for osteoarthritis of the knee. J Rheumatol 2006; 33: 951-956.
27. Diracoglu D, Vural M, Baskent A et al. The effect of viscosupplementation on neuromuscular control of the knee in patients with osteoarthritis. J Back Musculoskelet Rehabil 2009; 22: 1-9.
28. Chevalier X, Jerosch J, Goupille P et al. Single, intra-articular treatment with 6 ml hylan G-F 20 in patients with symptomatic primary osteoarthritis of the knee: a randomised, multicentre, double-blind, placebo controlled trial. Ann Rheum Dis 2010; 69: 113-119.