Association between urinary levels of bisphenol-A and estrogen metabolism in Korean adults

Science of the Total Environment

Volumn 470-471, Issue , 2014, Pages 1401-1407

  Kim, Eun Jee ^a,b   Lee, Dongho ^b   Chung, Bong Chul ^a   Pyo, Heesoo ^a   Lee, Jeongae ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Korea University   (South Korea)

Author keywords

Bisphenol A; Estrogen metabolism; Hydroxylase; Steroid hormone; Urine

Indexed keywords

BODY FLUIDS; GAS CHROMATOGRAPHY; PHENOLS; PHYSIOLOGY; STEROID HORMONES;

BIOMONITORING PROGRAMS; BISPHENOL A; CUMULATIVE EXPOSURES; ENDOCRINE DISRUPTING CHEMICALS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HYDROXYLASES; HYDROXYLATED METABOLITES; URINE;

METABOLISM;

16ALPHA HYDROXYESTRONE; 16KETO 17BETA ESTRADIOL; 17 EPIESTRIOL; 17ALPHA ESTRADIOL; 2 HYDROXYESTRADIOL; 2 HYDROXYESTRIOL; 2 HYDROXYESTRONE; 2 METHOXY 17BETA ESTRADIOL; 2 METHOXYESTRONE; 4 HYDROXYESTRADIOL; 4 HYDROXYESTRONE; 4 METHOXY 17BETA ESTRADIOL; 4 METHOXYESTRONE; 4,4' ISOPROPYLIDENEDIPHENOL; EPIESTRIOL; ESTRADIOL; ESTRIOL; ESTROGEN; ESTRONE; UNCLASSIFIED DRUG;

ADULT; BIOACCUMULATION; ENDOCRINE DISRUPTOR; ESTROGENIC COMPOUND; HORMONE; METABOLISM; PHENOL; POLLUTION EXPOSURE; STEROID; URINE;

ADULT; AGED; ARTICLE; ESTROGEN METABOLISM; ESTROGEN URINE LEVEL; ETHNIC GROUP; FEMALE; HUMAN; HUMAN CELL; HYDROLYSIS; KOREAN; LONG TERM EXPOSURE; MALE; MASS FRAGMENTOGRAPHY; MIDDLE AGED; PRIORITY JOURNAL; URINALYSIS; YOUNG ADULT;

KOREA;

16-EPI-E3; 16-EPIESTRIOL; 16KETO-17Β-ESTRADIOL&16Α-HYDROXYESTRONE; 16KETO-E2&16Α-OH-E1; 17-EPI-E3; 17-EPIESTRIOL; 17Α-E2; 17Α-ESTRADIOL; 17Β-ESTRADIOL; 2-HYDROXY-17Β-ESTRADIOL; 2-HYDROXYESTRIOL; 2-HYDROXYESTRONE; 2-MEO-E1; 2-MEO-E2; 2-METHOXY-17Β-ESTRADIOL; 2-METHOXYESTRONE; 2-OH-E1; 2-OH-E2; 2-OH-E3; 4-HYDROXY-17Β-ESTRADIOL; 4-HYDROXYESTRONE; 4-MEO-E1; 4-MEO-E2; 4-METHOXY-17Β-ESTRADIOL; 4-METHOXYESTRONE; 4-OH-E1; 4-OH-E2; BISPHENOL-A; BPA; E1; E2; E3; EDCS; ENDOCRINE DISRUPTING CHEMICALS; ESTRIOL; ESTROGEN METABOLISM; ESTRONE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GC-MS; HYDROXYLASE; STEROID HORMONE; URINE;

ADULT; BENZHYDRYL COMPOUNDS; ENDOCRINE DISRUPTORS; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL POLLUTANTS; ESTROGENS; FEMALE; HUMANS; MALE; PHENOLS; REPUBLIC OF KOREA;

EID: 84891634937     PISSN: 00489697     EISSN: 18791026     Source Type: Journal    
DOI: 10.1016/j.scitotenv.2013.07.040     Document Type: Article

References (45)

1. Barr D.B., Wilder L.C., Caudill S.P., Gonzalez A.J., Needham L.L., Pirkle J.L. Urinary creatinine concentrations in the U.S. population: implications for urinary biologic monitoring measurements. Environ Health Perspect 2005, 113(2):192-200.
2. Bolton J.L., Pisha E., Zhang F., Qiu S. Role of quinoids in estrogen carcinogenesis. Chem Res Toxicol 1998, 11:1113-1127.
3. Braun J.M., Yolton K., Dietrich K.N., Hornung R., Ye X., Calafat A.M. Prenatal bisphenol A exposure and early childhood behavior. Environ Health Perspect 2009, 117(12):1945-1952.
4. Butterworth M., Lau S.S., Monks T.J. 17 β-estradiol metabolism by hamster hepatic microsomes. Implications for the catechol-O-methyl transferase-mediated detoxication of catechol estrogens. Drug Metab Dispos 1996, 24(5):588-594.
5. Calafat A.M., Ye X., Wong L.Y., Reidy J.A., Needham L.L. Exposure of the U.S. population to bisphenol A and 4-tertiary-octylphenol: 2003-2004. Environ Health Perspect 2008, 116:39-44.
6. Casals-Casas C., Desvergne B. Endocrine disruptors: from endocrine to metabolic disruption. Annu Rev Physiol 2011, 73:135-162.
7. Cavalieri E.L., Rogan E.G. Is bisphenol A a weak estrogen like the natural estrogens and diethylstilbesterolα. IUBMB Life 2010, 62(10):746-751.
8. Cho S.H., Choi M.H., Kwon O.S., Lee W.Y., Chung B.C. Metabolic significance of bisphenol A induced oxidative stress in rat urine measured by liquid chromatography-mass spectrometry. J Appl Toxicol 2009, 29:110-117.
9. Dairkee S.H., Seok J., Champion S., Sayeed A., Mindrinos M., Xiao W., et al. Bisphenol A induces a profile of tumor aggressiveness in high-risk cells from breast cancer patients. Cancer Res 2008, 68(7):2076-2086.
10. Danzo B.J. The effects of environmental hormones on reproduction. Cell Mol Life Sci 1998, 54:1249-1264.
11. Fernandez S.V., Russo J. Estrogen and xenoestrogens in breast cancer. Toxicol Pathol 2010, 38:110-122.
12. Fotsis T., Zhang Y., Pepper M.S., Adlercreutz H., Montesano R., Nawroth P.P., et al. The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growth. Nature 1994, 368:237-239.
13. Gailwad N.W., Yang L., Muti P., Meza J.L., Pruthi S., Ingle J.N., et al. The molecular etiology of breast cancer: evidence from biomarkers of risk. Int J Cancer 2008, 122:1949-1957.
14. Hess-Wilson J.K. Bisphenol A, may reduce the efficacy of androgen deprivation therapy in prostate cancer. Cancer Causes Control 2009, 20:1029-1037.
15. Howdeshell K.L., Hotchkiss A.K., Thayer K.A., Vandenberg J.G., Vom Saal F.S. Exposure to bisphenol A advances puberty. Nature 1999, 401:763-764.
16. Husdan H., Rapoport A. Estimation of creatinine by the Jaffe reaction. A comparison of three methods. Clin Chem 1968, 14:222-238.
17. Im A., Vogel V.G., Ahrendt G., Lloyd S., Ragin C., Carte S., et al. Urinary estrogen metabolites in women at high risk for breast cancer. Carcinogenesis 2009, 30:1532-1535.
18. Kang J.H., Kondo F., Katayama Y. Human exposure to bisphenol A. Toxicology 2006, 226(2-3):79-89.
19. Kuiper G.G., Carlsson B., Grandien K., Enmark E., Häggblad J., Nilsson S., et al. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta. Endocrinology 1997, 138:863-870.
20. Lang I.A., Galloway T.S., Scarlett A., Henley W.E., Depledge M., Wallance R.B., et al. Association of urinary bisphenol A concentration with medical disorders and laboratory abnormalities in adults. JAMA 2011, 300(11):1303-1310.
21. Lee Y.J., Ryu H.Y., Kim H.K., Min C.S., Lee J.H., Kim E., et al. Maternal and fetal exposure to bisphenol A in Korea. Reprod Toxicol 2008, 25:413-419.
22. Lee S.H., Kang S.M., Choi M.H., Lee J., Park M.J., Kim S.H., et al. Changes in steroid metabolism among girls with precocious puberty may not be associated with urinary levels of bisphenol A. Reprod Toxicol 2013, 10.1016/j.reprotox.2013.03.008.
23. Li X., Ying G.G., Zhao J.L., Chen Z.F., Lai H.J. Su HC 4-Nonylphenol, bisphenol-A and triclosan levels in human urine of children and students in China, and the effects of drinking these bottled materials on the levels. Environ Int 2013, 52:81-86.
24. Mahalingaiah S., Meeker J.D., Pearson K.R., Calafat A.M., Ye X., Petrozza J. Hauser R temporal variability and predictors of urinary bisphenol A concentrations in men and women. Environ Health Perspect 2008, 116(2):173-178.
25. Meeker J.D., Calafat A.M., Hauser R. Urinary bisphenol-A concentrations in relation to serum thyroid and reproductive hormone levels in men from an infertility clinic. Environ Sci Technol 2010, 44:1458-1463.
26. Melzer D., Harries L., Cipelli R., Henley W., Money C., McCormack P., et al. Bisphenol A exposure is associated with in vivo estrogenic gene expression in adults. Environ Health Perspect 2011, 119:1788-1793.
27. Miodovnik A., Engel S.M., Zhu C., Ye X., Soorya L.V. Endocrine disruptors and childhood social impairment. Neurotoxicology 2011, 32:261-267.
28. Moon J.-Y., Jung H.-J., Moon M.H., Chung B.C., Choi M.H. Heat-map visualization of gas chromatography-mass spectrometry based quantitative signatures on steroid metabolism. J Am Soc Mass Spectrom 2009, 20:1626-1637.
29. Moon J.-Y., Ha Y.W., Moon M.H., Chung B.C., Choi M.H. Systematic error in gas chromatography-mass spectrometry-based quantification of hydrolyzed urinary steroids. Cancer Epidemiol Biomarkers Prev 2010, 19(2):388-397.
30. Nakamura D., Yanagiba Y., Duan Z., Ito Y., Okamura A., Asaeda N., et al. Bisphenol A may cause testosterone reduction by adversely affection both testis and pituitary systems similar to estradiol. Toxicol Lett 2010, 194:16-25.
31. Parl F.F., Dawling S., Roodi N., Crooke P.S. Estrogen metabolism and breast cancer: a risk model. Ann N Y Acad Sci 2009, 1155:68-75.
32. Richter C.A., Birnbaum L.S., Farabollini F., Newbold R.R., Rubin B.S., Talsness C.E., et al. In vivo effects of bisphenol A in laboratory rodent studies. Reprod Toxicol 2007, 24:199-224.
33. Takeshita A., Koibuchi N., Oka J., Taguchi M., Shishiba Y., Ozawa Y. Bisphenol-A, an environmental estrogen, activates the human orphan nuclear receptor, steroid and xenobiotic receptor-mediated transcription. Eur J Endocrinol 2001, 145:513-517.
34. Tsutsumi O. Assessment of human contamication of estrogenic endocrine-disrupting chemicals and their risk for human reproduction. J Steroid Biochem Mol Biol 2005, 93:325-330.
35. Ursin G., London S., Stanczyk F.Z., Gentzschein E., Paganini-Hill A., Ross R.K., et al. Urinary 2-hydroxyestrone/16α-hydroxyestrone ratio and risk of breast cancer in postmenopausal women. J Natl Cancer Inst 1999, 91:1067-1072.
36. Vandenberg L.N., Hauser R., Marcus M., Olea N., Welshons W.V. Human exposure to bisphenol A (BPA). Reprod Toxicol 2007, 24(2):139-177.
37. Vandenberg L.N., Chahoud I., Heindel J.J., Padmanabhan V., Paumgartten F.J.R., Schoenfelder G. Urinary, circulating, and tissue biomonitoring studies indicate widespread exposure to bisphenol A. Environ Health Perspect 2010, 118:1055-1070.
38. Welshons W.V., Nagel S.C., Vom Saal F.S. Large effects from small exposures, III. Endocrine mechanisms mediating effects of bisphenol A at levels of human exposure. Endocrinology 2006, 147:S56-S69.
39. Wetherill Y.B., Akingbemi B.T., Kanno J., McLachlan J.A., Nadal A., Sonnenschein C., et al. In vitro molecular mechanisms of bisphenol A action. Reprod Toxicol 2007, 24:178-198.
40. Wolff M.S., Britton J.A., Boguski L., Hochman S., Maloney N., Serra N., et al. Environmental exposures and puberty in inner-city girls. Environ Res 2008, 107:393-400.
41. Wolstenholme J.T., Rissman E.F., Connelly J.J. The role of bisphenol-A in shaping the brain, epigenome and behavior. Horm Behav 2011, 59(3):296-305.
42. Yamano Y., Miyakawa S., Iizumi K., Itoh H., Iwasaki M., Tsugane S., et al. Long-term study of urinary bisphenol A in elementary school children. Environ Health Prev Med 2008, 13:332-337.
43. Yokota H., Iwano H., Endo M., Kobayashi T., Inoue H., Ikushiro S.I. Glucuronidation of the environmental oestrogne bisphenol A by an isoform of UDP-glucuronosyltransterase, UGT2B1, in the rat liver. Biochem Soc 1999, 340:405-409.
44. Zhu B.T., Conney A.H. Is 2-methoxyestradiol an endogenous estrogen metabolite that inhibits mammary carcinogenesisα. Cancer Res 1998, 58:2269-2277.
45. Ziegler R.G., Rossi S.C., Fears T.R., Bradlow H.L., Adlercreutz H., Sepkovic D., et al. Quantifying estrogen metabolism: an evaluation of the reproducibility and validity of enzyme immunoassays for 2-hydroxyestrone and 16a-ydroxyestrone in urine. Environ Health Perspect 1997, 105(Suppl. 3):607-614.