The gene cutA of Fusarium fujikuroi, encoding a protein of the haloacid dehalogenase family, is involved in osmotic stress and glycerol metabolism

Microbiology (United Kingdom)

Volumn 160, Issue PART 1, 2014, Pages 26-36

  García Martínez, Jorge ^a   Castrillo, Marta ^a   Avalos, Javier ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CUTA PROTEIN; FUNGAL PROTEIN; FUNGAL RNA; GLYCEROL DEHYDROGENASE; MESSENGER RNA; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENZYME METABOLISM; FUNGAL GENOME; FUNGUS GROWTH; FUNGUS MUTANT; FUSARIUM FUJIKUROI; FUSARIUM GRAMINEARUM; FUSARIUM MONILIFORME; FUSARIUM OXYSPORUM; GENE EXPRESSION; GROWTH INHIBITION; HEAT SHOCK; HYPEROSMOTIC STRESS; NONHUMAN; OSMOLARITY; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; WILD TYPE;

FUSARIUM; GENE DELETION; GENE EXPRESSION REGULATION, BACTERIAL; GENE ORDER; GLYCEROL; HYDROLASES; OSMOTIC PRESSURE; SODIUM CHLORIDE; STRESS, PHYSIOLOGICAL;

EID: 84891608017     PISSN: 13500872     EISSN: 14652080     Source Type: Journal    
DOI: 10.1099/mic.0.071761-0     Document Type: Article

References (46)

1. Avalos, J. & Corrochano, L. M. (2013). Carotenoid biosynthesis in Neurospora. In Neurospora: Genomics and Molecular Biology, pp. 227-241. Edited by D. P. Kasbekar & K. McCluskey. Norfolk: Caister Academic Press.
2. Avalos, J. & Estrada, A. F. (2010). Regulation by light in Fusarium. Fungal Genet Biol 47, 930-938.
3. Avalos, J., Casadesús, J. & Cerdá-Olmedo, E. (1985). Gibberella fujikuroi mutants obtained with UV radiation and N-methyl-N9-nitro-N-nitrosoguanidine. Appl Environ Microbiol 49, 187-191.
4. Avalos, J., Cerda-Olmedo, E., Reyes, F. & Barrero, A. F. (2007). Gibberellins and other metabolites of Fusarium fujikuroi and related fungi. Curr Org Chem 11, 721-737.
5. Cartharius, K., Frech, K., Grote, K., Klocke, B., Haltmeier, M., Klingenhoff, A., Frisch, M., Bayerlein, M. & Werner, T. (2005). MatInspector and beyond: promoter analysis based on transcription factor binding sites. Bioinformatics 21, 2933-2942.
6. Castrillo, M., García-Martínez, J. & Avalos, J. (2013). Light-dependent functions of the Fusarium fujikuroi CryD DASH cryptochrome in development and secondary metabolism. Appl Environ Microbiol 79, 2777-2788.
7. De Vries, R. P., Flitter, S. J., van de Vondervoort, P. J., Chaveroche, M. K., Fontaine, T., Fillinger, S., Ruijter, G. J., d'Enfert, C. & Visser, J. (2003). Glycerol dehydrogenase, encoded by gldB is essential for osmotolerance in Aspergillus nidulans. Mol Microbiol 49, 131-141.
8. Diano, A., Bekker-Jensen, S., Dynesen, J. & Nielsen, J. (2006). Polyol synthesis in Aspergillus niger: influence of oxygen availability, carbon and nitrogen sources on the metabolism. Biotechnol Bioeng 94, 899-908.
9. Díaz-Sánchez, V., Avalos, J. & Limón, M. C. (2012). Identification and regulation of fusA, the polyketide synthase gene responsible for fusarin production in Fusarium fujikuroi. Appl Environ Microbiol 78, 7258-7266.
10. Ellis, S. W., Grindle, M. & Lewis, D. H. (1991). Effect of osmotic stress on yield and polyol content of dicarboximide-sensitive and-resistant strains of Neurospora crassa. Mycol Res 95, 457-464.
11. Estrada, A. F. & Avalos, J. (2008). The White Collar protein WcoA of Fusarium fujikuroi is not essential for photocarotenogenesis, but is involved in the regulation of secondary metabolism and conidiation. Fungal Genet Biol 45, 705-718.
12. Fillinger, S., Chaveroche, M. K., van Dijck, P., de Vries, R., Ruijter, G., Thevelein, J. & d'Enfert, C. (2001a). Trehalose is required for the acquisition of tolerance to a variety of stresses in the filamentous fungus Aspergillus nidulans. Microbiology 147, 1851-1862.
13. Fillinger, S., Ruijter, G., Tamás, M. J., Visser, J., Thevelein, J. M. & d'Enfert, C. (2001b). Molecular and physiological characterization of the NAD-dependent glycerol 3-phosphate dehydrogenase in the filamentous fungus Aspergillus nidulans. Mol Microbiol 39, 145-157.
14. Fujimura, M., Ochiai, N., Ichiishi, A., Usami, R., Horikoshi, K. & Yamaguchi, I. (2000). Sensitivity to phenylpyrrole fungicides and abnormal glycerol accumulation in os and cut mutant strains of Neurospora crassa. J Pestic Sci 25, 31-36.
15. Fujimura, M., Ochiai, N., Oshima, M., Motoyama, T., Ichiishi, A., Usami, R., Horikoshi, K. & Yamaguchi, I. (2003). Putative homologs of SSK22 MAPKK kinase and PBS2 MAPK kinase of Saccharomyces cerevisiae encoded by os-4 and os-5 genes for osmotic sensitivity and fungicide resistance in Neurospora crassa. Biosci Biotechnol Biochem 67, 186-191.
16. Furukawa, K., Hoshi, Y., Maeda, T., Nakajima, T. & Abe, K. (2005). Aspergillus nidulans HOG pathway is activated only by two-component signalling pathway in response to osmotic stress. Mol Microbiol 56, 1246-1261.
17. García-Martínez, J., Adám, A. L. & Avalos, J. (2012). Adenylyl cyclase plays a regulatory role in development, stress resistance and secondary metabolism in Fusarium fujikuroi. PLoS ONE 7, e28849.
18. Harding, R. W., Philip, D. Q., Drozdowicz, B. Z. & Williams, N. P. (1984). A Neurospora crassa mutant which overaccumulates carotenoid pigments. Neurospora Newsl 31, 23-25.
19. Jojima, T., Igari, T., Gunji, W., Suda, M., Inui, M. & Yukawa, H. (2012). Identification of a HAD superfamily phosphatase, HdpA, involved in 1, 3-dihydroxyacetone production during sugar catabolism in Corynebacterium glutamicum. FEBS Lett 586, 4228-4232.
20. Krantz, M., Becit, E. & Hohmann, S. (2006). Comparative genomics of the HOG-signalling system in fungi. Curr Genet 49, 137-151.
21. Kuznetsova, E., Proudfoot, M., González, C. F., Brown, G., Omelchenko, M. V., Borozan, I., Carmel, L., Wolf, Y. I., Mori, H. & other authors (2006). Genome-wide analysis of substrate specificities of the Escherichia coli haloacid dehalogenase-like phosphatase family. J Biol Chem 281, 36149-36161.
22. Larkin, M. A., Blackshields, G., Brown, N. P., Chenna, R., McGettigan, P. A., McWilliam, H., Valentin, F., Wallace, I. M., Wilm, A. & other authors (2007). CLUSTAL W and CLUSTAL_X version 2. 0. Bioinformatics 23, 2947-2948.
23. Lew, R. R. (2011). How does a hypha grow? The biophysics of pressurized growth in fungi. Nat Rev Microbiol 9, 509-518.
24. Lew, R. R. & Levina, N. N. (2007). Turgor regulation in the osmosensitive cut mutant of Neurospora crassa. Microbiology 153, 1530-1537.
25. Limón, M. C., Rodríguez-Ortiz, R. & Avalos, J. (2010). Bikaverin production and applications. Appl Microbiol Biotechnol 87, 21-29.
26. Mays, L. L. (1969). Isolation, characterization, and genetic analysis of osmotic mutants of Neurospora crassa. Genetics 63, 781-794.
27. Nevoigt, E. & Stahl, U. (1997). Osmoregulation and glycerol metabolism in the yeast Saccharomyces cerevisiae. FEMS Microbiol Rev 21, 231-241.
28. Ni, M. & Yu, J. H. (2007). A novel regulator couples sporogenesis and trehalose biogenesis in Aspergillus nidulans. PLoS ONE 2, e970.
29. O'Rourke, S. M., Herskowitz, I. & O'Shea, E. K. (2002). Yeast go the whole HOG for the hyperosmotic response. Trends Genet 18, 405-412.
30. Pahlman, A. K., Granath, K., Ansell, R., Hohmann, S. & Adler, L. (2001). The yeast glycerol 3-phosphatases Gpp1p and Gpp2p are required for glycerol biosynthesis and differentially involved in the cellular responses to osmotic, anaerobic, and oxidative stress. J Biol Chem 276, 3555-3563.
31. Perkins, D. D., Radford, A. & Sachs, M. S. (2001). The Neurospora Compendium. Chromosomal Loci. San Diego, CA: Academic Press.
32. Proctor, R. H., Hohn, T. M. & McCormick, S. P. (1997). Restoration of wild-type virulence to Tri5 disruption mutants of Gibberella zeae via gene reversion and mutant complementation. Microbiology 143, 2583-2591.
33. Punt, P. J., Oliver, R. P., Dingemanse, M. A., Pouwels, P. H. & van den Hondel, C. A. M. J. J. (1987). Transformation of Aspergillus based on the hygromycin B resistance marker from Escherichia coli. Gene 56, 117-124.
34. Reed, R. H., Chudek, J. A., Foster, R. & Gadd, G. M. (1987). Osmotic significance of glycerol accumulation in exponentially growing yeasts. Appl Environ Microbiol 53, 2119-2123.
35. Ruijter, G. J., Visser, J. & Rinzema, A. (2004). Polyol accumulation by Aspergillus oryzae at low water activity in solid-state fermentation. Microbiology 150, 1095-1101.
36. Sambrook, J. & Russell, D. W. (2001). Molecular Cloning: a Laboratory Manual, 3rd edn. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
37. Schumacher, M. M., Enderlin, C. S. & Selitrennikoff, C. P. (1997). The osmotic-1 locus of Neurospora crassa encodes a putative histidine kinase similar to osmosensors of bacteria and yeast. Curr Microbiol 34, 340-347.
38. Seifried, A., Schultz, J. & Gohla, A. (2013). Human HAD phosphatases: structure, mechanism, and roles in health and disease. FEBS J 280, 549-571.
39. Studt, L., Humpf, H. U. & Tudzynski, B. (2013). Signaling governed by G proteins and cAMP is crucial for growth, secondary metabolism and sexual development in Fusarium fujikuroi. PLoS ONE 8, e58185.
40. Tudzynski, B. (2005). Gibberellin biosynthesis in fungi: genes, enzymes, evolution, and impact on biotechnology. Appl Microbiol Biotechnol 66, 597-611.
41. Weinkove, D., Poyatos, J. A., Greiner, H., Oltra, E., Avalos, J., Fukshansky, L., Barrero, A. F. & Cerdá-Olmedo, E. (1998). Mutants of Phycomyces with decreased gallic acid content. Fungal Genet Biol 25, 196-203.
42. Wiemann, P., Sieber, C. M., von Bargen, K. W., Studt, L., Niehaus, E. M., Espino, J. J., Huß, K., Michielse, C. B., Albermann, S. & other authors (2013). Deciphering the cryptic genome: genome-wide analyses of the rice pathogen Fusarium fujikuroi reveal complex regulation of secondary metabolism and novel metabolites. PLoS Pathog 9, e1003475.
43. Youssar, L. & Avalos, J. (2006). Light-dependent regulation of the gene cut-1 of Neurospora, involved in the osmotic stress response. Fungal Genet Biol 43, 752-763.
44. Youssar, L. & Avalos, J. (2007). Genetic basis of the ovc phenotype of Neurospora: identification and analysis of a 77 kb deletion. Curr Genet 51, 19-30.
45. Youssar, L., Schmidhauser, T. J. & Avalos, J. (2005). The Neurospora crassa gene responsible for the cut and ovc phenotypes encodes a protein of the haloacid dehalogenase family. Mol Microbiol 55, 828-838.
46. Zhang, Y., Lamm, R., Pillonel, C., Lam, S. & Xu, J. R. (2002). Osmoregulation and fungicide resistance: the Neurospora crassa os-2 gene encodes a HOG1 mitogen-activated protein kinase homologue. Appl Environ Microbiol 68, 532-538.