-
1
-
-
7844240131
-
Role of skeletal muscle in thiazolidinedione insulin sensitizer (PPARgamma agonist) action
-
Zierath JR, Ryder JW, Doebber T, Woods J, Wu M, Ventre J, Li Z, McCrary C, Berger J, Zhang B, Moller DE. Role of skeletal muscle in thiazolidinedione insulin sensitizer (PPARgamma agonist) action. Endocrinology. 1998;139: 5034-41.
-
(1998)
Endocrinology
, vol.139
, pp. 5034-5041
-
-
Zierath, J.R.1
Ryder, J.W.2
Doebber, T.3
Woods, J.4
Wu, M.5
Ventre, J.6
Li, Z.7
McCrary, C.8
Berger, J.9
Zhang, B.10
Moller, D.E.11
-
2
-
-
0027304282
-
Thiazolidinediones (AD-4833 and CS-045) improve hepatic insulin resistance in streptozotocin-induced diabetic rats
-
Tominaga M, Igarashi M, Daimon M, Eguchi H, Matsumoto M, Sekikawa A, Yamatani K, Sasaki H. Thiazolidinediones (AD-4833 and CS-045) improve hepatic insulin resistance in streptozotocin-induced diabetic rats. Endocr J. 1993;40: 343-9.
-
(1993)
Endocr J
, vol.40
, pp. 343-349
-
-
Tominaga, M.1
Igarashi, M.2
Daimon, M.3
Eguchi, H.4
Matsumoto, M.5
Sekikawa, A.6
Yamatani, K.7
Sasaki, H.8
-
3
-
-
0036930844
-
Differential regulation of adiponectin secretion from cultured human omental and subcutaneous adipocytes: effects of insulin and rosiglitazone
-
Motoshima H, Wu X, Sinha MK, Hardy VE, Rosato EL, Barbot DJ, Rosato FE, Goldstein BJ. Differential regulation of adiponectin secretion from cultured human omental and subcutaneous adipocytes: effects of insulin and rosiglitazone. J Clin Endocrinol Metab. 2002;87: 5662-7.
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 5662-5667
-
-
Motoshima, H.1
Wu, X.2
Sinha, M.K.3
Hardy, V.E.4
Rosato, E.L.5
Barbot, D.J.6
Rosato, F.E.7
Goldstein, B.J.8
-
4
-
-
33745834319
-
Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome
-
Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K, Tobe K. Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. J Clin Invest. 2006;116: 1784-92.
-
(2006)
J Clin Invest.
, vol.116
, pp. 1784-1792
-
-
Kadowaki, T.1
Yamauchi, T.2
Kubota, N.3
Hara, K.4
Ueki, K.5
Tobe, K.6
-
5
-
-
37549040190
-
The physiological and pathophysiological role of adiponectin and adiponectin receptors in the peripheral tissues and CNS
-
Kadowaki T, Yamauchi T, Kubota N. The physiological and pathophysiological role of adiponectin and adiponectin receptors in the peripheral tissues and CNS. FEBS Lett. 2008;582: 74-80.
-
(2008)
FEBS Lett
, vol.582
, pp. 74-80
-
-
Kadowaki, T.1
Yamauchi, T.2
Kubota, N.3
-
6
-
-
26244453309
-
PROactive investigators. Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial
-
Dormandy JA, Charbonnel B, Eckland DJ, Erdmann E, Massi-Benedetti M, Moules IK, Skene AM, Tan MH, Lefebvre PJ, Murray GD, Standl E, Wilcox RG, Wilhelmsen L, Betteridge J, Birkeland K, Golay A, Heine RJ, Koranyi L, Laakso M, Mokan M, Norkus A, Pirags V, Podar T, Scheen A, Scherbaum W, Schernthaner G, Schmitz O, Skrha J, Smith U, Taton J. PROactive investigators. Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial. Lancet. 2005;366: 1279-89.
-
(2005)
Lancet
, vol.366
, pp. 1279-1289
-
-
Dormandy, J.A.1
Charbonnel, B.2
Eckland, D.J.3
Erdmann, E.4
Massi-Benedetti, M.5
Moules, I.K.6
Skene, A.M.7
Tan, M.H.8
Lefebvre, P.J.9
Murray, G.D.10
Standl, E.11
Wilcox, R.G.12
Wilhelmsen, L.13
Betteridge, J.14
Birkeland, K.15
Golay, A.16
Heine, R.J.17
Koranyi, L.18
Laakso, M.19
Mokan, M.20
Norkus, A.21
Pirags, V.22
Podar, T.23
Scheen, A.24
Scherbaum, W.25
Schernthaner, G.26
Schmitz, O.27
Skrha, J.28
Smith, U.29
Taton, J.30
more..
-
7
-
-
0344304678
-
Thiazolidinedione use, fluid retention, and congestive heart failure: a consensus statement from the American Heart Association and American Diabetes Association
-
American Heart AssociationAmerican Diabetes Association
-
Nesto RW, Bell D, Bonow RO, Fonseca V, Grundy SM, Horton ES, Le Winter M, Porte D, Semenkovich CF, Smith S, Young LH, Kahn R, American Heart Association, American Diabetes Association. Thiazolidinedione use, fluid retention, and congestive heart failure: a consensus statement from the American Heart Association and American Diabetes Association. Circulation. 2003;108: 2941-8.
-
(2003)
Circulation
, vol.108
, pp. 2941-2948
-
-
Nesto, R.W.1
Bell, D.2
Bonow, R.O.3
Fonseca, V.4
Grundy, S.M.5
Horton, E.S.6
Le Winter, M.7
Porte, D.8
Semenkovich, C.F.9
Smith, S.10
Young, L.H.11
Kahn, R.12
-
8
-
-
33745621867
-
Safety and efficacy of low-dose pioglitazone (7.5 mg/day) vs. standard-dose pioglitazone (15 mg/day) in Japanese women with type 2 diabetes mellitus
-
Majima T, Komatsu Y, Doi K, Shigemoto M, Takagi C, Fukao A, Corners J, Nakao K. Safety and efficacy of low-dose pioglitazone (7. 5 mg/day) vs. standard-dose pioglitazone (15 mg/day) in Japanese women with type 2 diabetes mellitus. Endocr J. 2006;53: 325-30.
-
(2006)
Endocr J
, vol.53
, pp. 325-330
-
-
Majima, T.1
Komatsu, Y.2
Doi, K.3
Shigemoto, M.4
Takagi, C.5
Fukao, A.6
Corners, J.7
Nakao, K.8
-
9
-
-
0036517099
-
Dose-response effect of pioglitazone on insulin sensitivity and insulin secretion in type 2 diabetes
-
Miyazaki Y, Matsuda M, DeFronzo RA. Dose-response effect of pioglitazone on insulin sensitivity and insulin secretion in type 2 diabetes. Diabetes Care. 2002;25: 517-23.
-
(2002)
Diabetes Care
, vol.25
, pp. 517-523
-
-
Miyazaki, Y.1
Matsuda, M.2
DeFronzo, R.A.3
-
10
-
-
33646852805
-
Pioglitazone ameliorates insulin resistance and diabetes by both adiponectin-dependent and -independent pathways
-
Kubota N, Terauchi Y, Kubota T, Kumagai H, Itoh S, Satoh H, Yano W, Ogata H, Tokuyama K, Takamoto I, Mineyama T, Ishikawa M, Moroi M, Sugi K, Yamauchi T, Ueki K, Tobe K, Noda T, Nagai R, Kadowaki T. Pioglitazone ameliorates insulin resistance and diabetes by both adiponectin-dependent and -independent pathways. J Biol Chem. 2006;281: 8748-55.
-
(2006)
J Biol Chem
, vol.281
, pp. 8748-8755
-
-
Kubota, N.1
Terauchi, Y.2
Kubota, T.3
Kumagai, H.4
Itoh, S.5
Satoh, H.6
Yano, W.7
Ogata, H.8
Tokuyama, K.9
Takamoto, I.10
Mineyama, T.11
Ishikawa, M.12
Moroi, M.13
Sugi, K.14
Yamauchi, T.15
Ueki, K.16
Tobe, K.17
Noda, T.18
Nagai, R.19
Kadowaki, T.20
more..
-
11
-
-
34548672388
-
Short-term low-dosage pioglitazone treatment improves vascular dysfunction in patients with type 2 diabetes
-
Maegawa H, Nishio Y, Nakao K, Ugi S, Maeda K, Uzu T, Kashiwagi A. Short-term low-dosage pioglitazone treatment improves vascular dysfunction in patients with type 2 diabetes. Endocrin J. 2007;54: 613-8.
-
(2007)
Endocrin J.
, vol.54
, pp. 613-618
-
-
Maegawa, H.1
Nishio, Y.2
Nakao, K.3
Ugi, S.4
Maeda, K.5
Uzu, T.6
Kashiwagi, A.7
-
13
-
-
0023928141
-
The in vitro and ex vivo antiplatelet effect of TRK-100, a stable prostacyclin analog, in several species
-
Nishio S, Matsuura H, Kanai N, Fukatsu Y, Hirano T, Nishikawa N, Kameoka K, Umetsu T. The in vitro and ex vivo antiplatelet effect of TRK-100, a stable prostacyclin analog, in several species. Jpn J Pharmacol. 1988;47: 1-10.
-
(1988)
Jpn J Pharmacol
, vol.47
, pp. 1-10
-
-
Nishio, S.1
Matsuura, H.2
Kanai, N.3
Fukatsu, Y.4
Hirano, T.5
Nishikawa, N.6
Kameoka, K.7
Umetsu, T.8
-
14
-
-
0034713816
-
2 analogue, for intermittent claudication: a double-blind, randomized, multicenter controlled trial. Beraprost et Claudication Intermittente (BERCI) Research Group
-
2 analogue, for intermittent claudication: a double-blind, randomized, multicenter controlled trial. Beraprost et Claudication Intermittente (BERCI) Research Group. Circulation. 2000;102: 426-31.
-
(2000)
Circulation
, vol.102
, pp. 426-431
-
-
Lièvre, M.1
Morand, S.2
Besse, B.3
Fiessinger, J.4
Boissel, J.5
-
15
-
-
0036569119
-
Effects of beraprost sodium, an oral prostacyclin analogue, in patients with pulmonary arterial hypertension: a randomized, double-blind, placebo-controlled trial
-
Arterial Pulmonary Hypertension and Beraprost European (ALPHABET) Study Group
-
Galiè N, Humbert M, Vachiéry JL, Vizza CD, Kneussl M, Manes A, Sitbon O, Torbicki A, Delcroix M, Naeije R, Hoeper M, Chaouat A, Morand S, Besse B, Simonneau G, Arterial Pulmonary Hypertension and Beraprost European (ALPHABET) Study Group. Effects of beraprost sodium, an oral prostacyclin analogue, in patients with pulmonary arterial hypertension: a randomized, double-blind, placebo-controlled trial. J Am Coll Cardiol. 2002;39: 1496-502.
-
(2002)
J Am Coll Cardiol
, vol.39
, pp. 1496-1502
-
-
Galiè, N.1
Humbert, M.2
Vachiéry, J.L.3
Vizza, C.D.4
Kneussl, M.5
Manes, A.6
Sitbon, O.7
Torbicki, A.8
Delcroix, M.9
Naeije, R.10
Hoeper, M.11
Chaouat, A.12
Morand, S.13
Besse, B.14
Simonneau, G.15
-
17
-
-
79952142784
-
Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle
-
Kubota T, Kubota N, Kumagai H, Yamaguchi S, Kozono H, Takahashi T, Inoue M, Itoh S, Takamoto I, Sasako T, Kumagai K, Kawai T, Hashimoto S, Kobayashi T, Sato M, Tokuyama K, Nishimura S, Tsunoda M, Ide T, Murakami K, Yamazaki T, Ezaki O, Kawamura K, Masuda H, Moroi M, Sugi K, Oike Y, Shimokawa H, Yanagihara N, Tsutsui M, Terauchi Y, Tobe K, Nagai R, Kamata K, Inoue K, Kodama T, Ueki K, Kadowaki T. Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle. Cell Metab. 2011;13: 294-307.
-
(2011)
Cell Metab
, vol.13
, pp. 294-307
-
-
Kubota, T.1
Kubota, N.2
Kumagai, H.3
Yamaguchi, S.4
Kozono, H.5
Takahashi, T.6
Inoue, M.7
Itoh, S.8
Takamoto, I.9
Sasako, T.10
Kumagai, K.11
Kawai, T.12
Hashimoto, S.13
Kobayashi, T.14
Sato, M.15
Tokuyama, K.16
Nishimura, S.17
Tsunoda, M.18
Ide, T.19
Murakami, K.20
Yamazaki, T.21
Ezaki, O.22
Kawamura, K.23
Masuda, H.24
Moroi, M.25
Sugi, K.26
Oike, Y.27
Shimokawa, H.28
Yanagihara, N.29
Tsutsui, M.30
Terauchi, Y.31
Tobe, K.32
Nagai, R.33
Kamata, K.34
Inoue, K.35
Kodama, T.36
Ueki, K.37
Kadowaki, T.38
more..
-
18
-
-
45549087567
-
Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding
-
Kubota N, Kubota T, Itoh S, Kumagai H, Kozono H, Takamoto I, Mineyama T, Ogata H, Tokuyama K, Ohsugi M, Sasako T, Moroi M, Sugi K, Kakuta S, Iwakura Y, Noda T, Ohnishi S, Nagai R, Tobe K, Terauchi Y, Ueki K, Kadowaki T. Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding. Cell Metab. 2008;8: 49-64.
-
(2008)
Cell Metab
, vol.8
, pp. 49-64
-
-
Kubota, N.1
Kubota, T.2
Itoh, S.3
Kumagai, H.4
Kozono, H.5
Takamoto, I.6
Mineyama, T.7
Ogata, H.8
Tokuyama, K.9
Ohsugi, M.10
Sasako, T.11
Moroi, M.12
Sugi, K.13
Kakuta, S.14
Iwakura, Y.15
Noda, T.16
Ohnishi, S.17
Nagai, R.18
Tobe, K.19
Terauchi, Y.20
Ueki, K.21
Kadowaki, T.22
more..
-
19
-
-
0242468543
-
Selective inhibition of 11 beta-hydroxysteroid dehydrogenase type 1 improves hepatic insulin sensitivity in hyperglycemic mice strains
-
Alberts P, Nilsson C, Selen G, Engblom LO, Edling NH, Norling S, Klingström G, Larsson C, Forsgren M, Ashkzari M, Nilsson CE, Fiedler M, Bergqvist E, Ohman B, Björkstrand E, Abrahmsen LB. Selective inhibition of 11 beta-hydroxysteroid dehydrogenase type 1 improves hepatic insulin sensitivity in hyperglycemic mice strains. Endocrinology. 2003;144: 4755-62.
-
(2003)
Endocrinology
, vol.144
, pp. 4755-4762
-
-
Alberts, P.1
Nilsson, C.2
Selen, G.3
Engblom, L.O.4
Edling, N.H.5
Norling, S.6
Klingström, G.7
Larsson, C.8
Forsgren, M.9
Ashkzari, M.10
Nilsson, C.E.11
Fiedler, M.12
Bergqvist, E.13
Ohman, B.14
Björkstrand, E.15
Abrahmsen, L.B.16
-
20
-
-
0028924908
-
Low-dose iloprost infusion improves insulin action in aged healthy subjects and NIDDM patients
-
Paolisso G, Di Maro G, D'Amore A, Passariello N, Gambardella A, Varricchio M, D'Onofrio F. Low-dose iloprost infusion improves insulin action in aged healthy subjects and NIDDM patients. Diabetes Care. 1995;18: 200-5.
-
(1995)
Diabetes Care
, vol.18
, pp. 200-205
-
-
Paolisso, G.1
Di Maro, G.2
D'Amore, A.3
Passariello, N.4
Gambardella, A.5
Varricchio, M.6
D'Onofrio, F.7
-
21
-
-
34249979025
-
Combination of dipeptidylpeptidase IV inhibitor and low dose thiazolidinedione: preclinical efficacy and safety in db/db mice
-
Roy S, Khanna V, Mittra S, Dhar A, Singh S, Mahajan DC, Priyadarsiny P, Davis JA, Sattigeri J, Saini KS, Bansal VS. Combination of dipeptidylpeptidase IV inhibitor and low dose thiazolidinedione: preclinical efficacy and safety in db/db mice. Life Sci. 2007;81: 72-9.
-
(2007)
Life Sci
, vol.81
, pp. 72-79
-
-
Roy, S.1
Khanna, V.2
Mittra, S.3
Dhar, A.4
Singh, S.5
Mahajan, D.C.6
Priyadarsiny, P.7
Davis, J.A.8
Sattigeri, J.9
Saini, K.S.10
Bansal, V.S.11
-
22
-
-
77955013179
-
Low-dose combination therapy with rosiglitazone and metformin to prevent type 2 diabetes mellitus (CANOE trial): a double-blind randomised controlled study
-
Zinman B, Harris SB, Neuman J, Gerstein HC, Retnakaran RR, Raboud J, Qi Y, Hanley AJ. Low-dose combination therapy with rosiglitazone and metformin to prevent type 2 diabetes mellitus (CANOE trial): a double-blind randomised controlled study. Lancet. 2010;376: 103-11.
-
(2010)
Lancet
, vol.376
, pp. 103-111
-
-
Zinman, B.1
Harris, S.B.2
Neuman, J.3
Gerstein, H.C.4
Retnakaran, R.R.5
Raboud, J.6
Qi, Y.7
Hanley, A.J.8
|