APOE polymorphism and carotid atherosclerosis in Korean population: The Dong-gu Study and the Namwon Study

Atherosclerosis

Volumn 232, Issue 1, 2014, Pages 180-185

  Shin, Min Ho ^a,h   Choi, Jin Su ^a   Rhee, Jung Ae ^a   Lee, Young Hoon ^c   Nam, Hae Sung ^d   Jeong, Seul Ki ^e   Park, Kyeong Soo ^f   Kim, Hye Yeon ^f   Ryu, So Yeon ^g   Choi, Seong Woo ^g   Kim, Hee Nam ^b   Song, Hye Rim ^a   Cauley, Jane A ^h   Kweon, Sun Seog ^a,b  

^a Chonnam National University Medical School   (South Korea)

^b Chonnam National University Research Institute of Medical Sciences   (South Korea)

^c Wonkwang University School of Medicine   (South Korea)

^d Chungnam National University   (South Korea)

^e Chonbuk National University Medical School   (South Korea)

^f Seonam University   (South Korea)

^g Chosun University College of Medicine   (South Korea)

^h UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Apolipoprotein E; Carotid artery plaque; Intima media thickness; Polymorphism

Indexed keywords

APOLIPOPROTEIN E;

ADULT; AGED; ARTERIAL WALL THICKNESS; ARTICLE; CAROTID ATHEROSCLEROSIS; CONTROLLED STUDY; DISEASE ASSOCIATION; ECHOGRAPHY; FEMALE; GENOTYPE; HUMAN; KOREA; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN POLYMORPHISM;

APOLIPOPROTEIN E; CAROTID ARTERY PLAQUE; INTIMA-MEDIA THICKNESS; POLYMORPHISM;

AGED; ALLELES; APOLIPOPROTEINS E; ASIAN CONTINENTAL ANCESTRY GROUP; CAROTID ARTERIES; CAROTID ARTERY DISEASES; CAROTID INTIMA-MEDIA THICKNESS; COHORT STUDIES; FEMALE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; ODDS RATIO; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; REPUBLIC OF KOREA;

EID: 84891594261     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2013.11.027     Document Type: Article

References (35)

1. Eichner J.E., Dunn S.T., Perveen G., et al. Apolipoprotein E polymorphism and cardiovascular disease: a HuGE review. Am J Epidemiol 2002, 155:487-495.
2. Mahley R.W. Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science 1988, 240:622-630.
3. Song Y., Stampfer M.J., Liu S. Meta-analysis: apolipoprotein E genotypes and risk for coronary heart disease. Ann Intern Med 2004, 141:137-147.
4. Davignon J., Gregg R.E., Sing C.F. Apolipoprotein E polymorphism and atherosclerosis. Arteriosclerosis 1988, 8:1-21.
5. Dallongeville J., Lussier-Cacan S., Davignon J. Modulation of plasma triglyceride levels by apoE phenotype: a meta-analysis. JLipid Res 1992, 33:447-454.
6. Cattin L., Fisicaro M., Tonizzo M., et al. Polymorphism of the apolipoprotein E gene and early carotid atherosclerosis defined by ultrasonography in asymptomatic adults. Arterioscler Thromb Vasc Biol 1997, 17:91-94.
7. Ilveskoski E., Loimaala A., Mercuri M.F., et al. Apolipoprotein E polymorphism and carotid artery intima-media thickness in a random sample of middle-aged men. Atherosclerosis 2000, 153:147-153.
8. Slooter A.J., Bots M.L., Havekes L.M., et al. Apolipoprotein E and carotid artery atherosclerosis: the Rotterdam Study. Stroke 2001, 32:1947-1952.
9. Haraki T., Takegoshi T., Kitoh C., et al. Carotid artery intima-media thickness and brachial artery flow-mediated vasodilation in asymptomatic Japanese male subjects amongst apolipoprotein E phenotypes. JIntern Med 2002, 252:114-120.
10. Volcik K.A., Barkley R.A., Hutchinson R.G., et al. Apolipoprotein E polymorphisms predict low density lipoprotein cholesterol levels and carotid artery wall thickness but not incident coronary heart disease in 12,491 ARIC Study participants. Am J Epidemiol 2006, 164:342-348.
11. Beilby J.P., Hunt C.C., Palmer L.J., et al. Apolipoprotein E gene polymorphisms are associated with carotid plaque formation but not with intima-media wall thickening: results from the Perth Carotid Ultrasound Disease Assessment Study (CUDAS). Stroke 2003, 34:869-874.
12. Elosua R., Ordovas J.M., Cupples L.A., et al. Association of APOE genotype with carotid atherosclerosis in men and women: the Framingham Heart Study. JLipid Res 2004, 45:1868-1875.
13. Debette S., Lambert J.C., Gariepy J., et al. New insight into the association of apolipoprotein E genetic variants with carotid plaques and intima-media thickness. Stroke 2006, 37:2917-2923.
14. Kogawa K., Nishizawa Y., Hosoi M., et al. Effect of polymorphism of apolipoprotein E and angiotensin-converting enzyme genes on arterial wall thickness. Diabetes 1997, 46:682-687.
15. Sass C., Zannad F., Herbeth B., et al. Apolipoprotein E4, lipoprotein lipase C447 and angiotensin-I converting enzyme deletion alleles were not associated with increased wall thickness of carotid and femoral arteries in healthy subjects from the Stanislas cohort. Atherosclerosis 1998, 140:89-95.
16. Hanon O., Girerd X., Luong V., et al. Association between the apolipoprotein E polymorphism and arterial wall thickness in asymptomatic adults. JHypertens 2000, 18:431-436.
17. Tabara Y., Kohara K., Nakura J., et al. Risk factor-gene interaction in carotid atherosclerosis: effect of gene polymorphisms of renin-angiotensin system. JHum Genet 2001, 46:278-284.
18. Kweon S.S., Shin M.H., Jeong S.K., et al. Cohort profile: the Namwon Study and the Dong-gu Study. Int J Epidemiol 2013, 10.1093/ije/dys244.
19. Hixson J.E., Vernier D.T. Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. JLipid Res 1990, 31:545-548.
20. Shin M.H., Kim H.N., Cui L.H., et al. The effect of apolipoprotein E polymorphism on lipid levels in Korean adults. JKorean Med Sci 2005, 20:361-366.
21. Friedewald W.T., Levy R.I., Fredrickson D.S. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972, 18:499-502.
22. Choi Y.H., Kim J.H., Kim D.K., et al. Distributions of ACE and APOE polymorphisms and their relations with dementia status in Korean centenarians. JGerontol A Biol Sci Med Sci 2003, 58:227-231.
23. Chun S., Min W.K., Kim J.W., et al. Apolipoprotein E polymorphism and serum lipoprotein(a) concentrations in a Korean male population. Ann Clin Biochem 2001, 38:129-134.
24. Katsuya T., Baba S., Ishikawa K., et al. Epsilon 4 allele of apolipoprotein E gene associates with lower blood pressure in young Japanese subjects: the Suita Study. JHypertens 2002, 20:2017-2021.
25. Howard B.V., Gidding S.S., Liu K. Association of apolipoprotein E phenotype with plasma lipoproteins in African-American and white young adults. The CARDIA Study. Coronary Artery Risk Development in Young Adults. Am J Epidemiol 1998, 148:859-868.
26. Paternoster L., Martinez Gonzalez N.A., Lewis S., et al. Association between apolipoprotein E genotype and carotid intima-media thickness may suggest a specific effect on large artery atherothrombotic stroke. Stroke 2008, 39:48-54.
27. Maezawa I., Nivison M., Montine K.S., et al. Neurotoxicity from innate immune response is greatest with targeted replacement of E4 allele of apolipoprotein E gene and is mediated by microglial p38MAPK. FASEB J 2006, 20:797-799.
28. Roselaar S.E., Daugherty A. Apolipoprotein E-deficient mice have impaired innate immune responses to Listeria monocytogenes invivo. JLipid Res 1998, 39:1740-1743.
29. Lynch J.R., Tang W., Wang H., et al. APOE genotype and an ApoE-mimetic peptide modify the systemic and central nervous system inflammatory response. JBiol Chem 2003, 278:48529-48533.
30. Pepe M.G., Curtiss L.K. Apolipoprotein E is a biologically active constituent of the normal immunoregulatory lipoprotein, LDL-In. JImmunol 1986, 136:3716-3723.
31. Jofre-Monseny L., Minihane A.M., Rimbach G. Impact of apoE genotype on oxidative stress, inflammation and disease risk. Mol Nutr Food Res 2008, 52:131-145.
32. Bennet A.M., Di Angelantonio E., Ye Z., et al. Association of apolipoprotein E genotypes with lipid levels and coronary risk. JAm Med Assoc 2007, 298:1300-1311.
33. Schaefer E.J., Lamon-Fava S., Cohn S.D., et al. Effects of age, gender, and menopausal status on plasma low density lipoprotein cholesterol and apolipoprotein B levels in the Framingham Offspring Study. JLipid Res 1994, 35:779-792.
34. Ophir G., Amariglio N., Jacob-Hirsch J., et al. Apolipoprotein E4 enhances brain inflammation by modulation of the NF-kappaB signaling cascade. Neurobiol Dis 2005, 20:709-718.
35. Paternoster L., Martinez-Gonzalez N.A., Charleton R., et al. Genetic effects on carotid intima-media thickness: systematic assessment and meta-analyses of candidate gene polymorphisms studied in more than 5000 subjects. Circ Cardiovasc Genet 2010, 3:15-21.