메뉴 건너뛰기




Volumn 101, Issue 1, 2014, Pages 147-153

Long gonadotropin-releasing hormone agonist versus short agonist versus antagonist regimens in poor responders undergoing in vitro fertilization: A randomized controlled trial

Author keywords

GnRH antagonist regimen; long GnRH agonist regimen; Poor ovarian response; RCT; short GnRH agonist regimen

Indexed keywords

CETRORELIX; GONADOTROPIN; HUMAN MENOPAUSAL GONADOTROPIN; NAFARELIN ACETATE; RECOMBINANT CHORIONIC GONADOTROPIN; RECOMBINANT FOLLITROPIN;

EID: 84891558045     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2013.09.035     Document Type: Article
Times cited : (91)

References (36)
  • 1
    • 0020665057 scopus 로고
    • Human menopausal gonadotropin/human chorionic gonadotropin follicular maturation for oocyte aspiration: Phase II, 1981
    • J.E. Garcia, G.S. Jones, A.A. Acosta, and G. Wright Jr. Human menopausal gonadotrophin/human chorionic gonadotrophin follicular maturation for oocyte aspiration/phase II, 1981 Fertil Steril 39 1983 174 179 (Pubitemid 13195405)
    • (1983) Fertility and Sterility , vol.39 , Issue.2 , pp. 174-179
    • Garcia, J.E.1    Jones, G.S.2    Acosta, A.A.3    Wright Jr., G.4
  • 2
    • 0032795963 scopus 로고    scopus 로고
    • A rational approach to the management of low responders in in-vitro fertilization
    • DOI 10.1093/humrep/14.7.1744
    • V. Karande, and N. Gleicher A rational approach to the management of low responders in in-vitro fertilization Humanit Rep 14 1999 1744 1748 (Pubitemid 29358689)
    • (1999) Human Reproduction , vol.14 , Issue.7 , pp. 1744-1748
    • Karande, V.1    Gleicher, N.2
  • 5
    • 0038236539 scopus 로고    scopus 로고
    • Conception rates following assisted reproduction in poor responder patients: A retrospective study in 300 consecutive cycles
    • U. Ulug, I. Ben-Shlomo, E. Turan, H.F. Erden, M.A. Akman, and M. Bahceci Conception rates following assisted reproduction in poor responder patients: a retrospective study in 300 consecutive cycles Reprod Biomed Online 6 2003 439 443 (Pubitemid 36849804)
    • (2003) Reproductive BioMedicine Online , vol.6 , Issue.4 , pp. 439-443
    • Ulug, U.1    Ben-Shlomo, I.2    Turan, E.3    Erden, H.F.4    Ali Akman, M.5    Bahceci, M.6
  • 6
    • 79959478992 scopus 로고    scopus 로고
    • Association between the number of eggs and live birth in IVF treatment: An analysis of 400,135 treatment cycles
    • S.K. Sunkara, V. Rittenberg, N. Raine-Fenning, S. Bhattacharya, J. Zamora, and A. Coomarasamy Association between the number of eggs and live birth in IVF treatment: an analysis of 400,135 treatment cycles Hum Reprod 26 2011 1768 1774
    • (2011) Hum Reprod , vol.26 , pp. 1768-1774
    • Sunkara, S.K.1    Rittenberg, V.2    Raine-Fenning, N.3    Bhattacharya, S.4    Zamora, J.5    Coomarasamy, A.6
  • 7
    • 37549040582 scopus 로고    scopus 로고
    • Interventions for "poor responders" to controlled ovarian hyperstimulation (COS) in in-vitro fertilisation (IVF)
    • S. Shanbhag, L. Aucott, S. Bhattacharya, M.A. Hamilton, and A.R. McTavish Interventions for "poor responders" to controlled ovarian hyperstimulation (COS) in in-vitro fertilisation (IVF) Cochrane Database Syst Rev 1 2007 CD004379
    • (2007) Cochrane Database Syst Rev , vol.1 , pp. 004379
    • Shanbhag, S.1    Aucott, L.2    Bhattacharya, S.3    Hamilton, M.A.4    McTavish, A.R.5
  • 8
    • 0026467005 scopus 로고
    • The routine use of gonadotropin releasing hormone agonists prior to in-vitro fertilization and gamete intrafallopian transfer: A meta-analysis of randomized controlled trials
    • E.G. Hughes, D.M. Fedorkow, and S. Daya The routine use of gonadotropin releasing hormone agonists prior to in-vitro fertilization and gamete intrafallopian transfer: a meta-analysis of randomized controlled trials Fertil Steril 58 1992 888 896
    • (1992) Fertil Steril , vol.58 , pp. 888-896
    • Hughes, E.G.1    Fedorkow, D.M.2    Daya, S.3
  • 9
    • 84921431249 scopus 로고    scopus 로고
    • Gonadotropin releasing hormone agonist protocols for pituitary desensitization in in vitro fertilization and gamete intrafallopian transfer cycles
    • S. Daya Gonadotropin releasing hormone agonist protocols for pituitary desensitization in in vitro fertilization and gamete intrafallopian transfer cycles Cochrane Database Syst Rev 2 2000 CD001299
    • (2000) Cochrane Database Syst Rev , vol.2 , pp. 001299
    • Daya, S.1
  • 10
    • 0025171986 scopus 로고
    • Follicular phase gonadotropin-releasing hormone agonist and human gonadotropins: A better alternative for ovulation induction in in vitro fertilization
    • J. Garcia, S. Padilla, J. Bayati, and T. Baramki Follicular phase gonadotropin-releasing hormone agonist and human gonadotropins: a better alternative for ovulation induction in in vitro fertilization Fertil Steril 53 1990 302 305 (Pubitemid 20076360)
    • (1990) Fertility and Sterility , vol.53 , Issue.2 , pp. 302-305
    • Garcia, J.E.1    Padilla, S.L.2    Bayati, J.3    Baramki, T.A.4
  • 11
    • 0021242183 scopus 로고
    • Medical hypophysectomy: I. Dose-response using a gonadotropin-releasing hormone antagonist
    • D. Kenigsberg, B.A. Littman, and G.D. Hodgen Medical hypophysectomy. I. Dose-response using a gonadotropin-releasing hormone antagonist Fertil Steril 42 1984 112 115 (Pubitemid 14086161)
    • (1984) Fertility and Sterility , vol.42 , Issue.1 , pp. 112-115
    • Kenigsberg, D.1    Littman, B.A.2    Hodgen, G.D.3
  • 13
    • 40149102534 scopus 로고    scopus 로고
    • A three-arm randomised controlled trial comparing gonadotrophin releasing hormone (GnRH) long agonist regimen versus short GnRH agonist regimen versus GnRH antagonist regimen in women with a history of poor ovarian response undergoing in vitro fertilisation (IVF) treatment: Poor Responders Intervention Trial (PRINT)
    • S.K. Sunkara, A. Coomarasamy, Y. Khalaf, and P. Braude A three-arm randomised controlled trial comparing gonadotrophin releasing hormone (GnRH) long agonist regimen versus short GnRH agonist regimen versus GnRH antagonist regimen in women with a history of poor ovarian response undergoing in vitro fertilisation (IVF) treatment: Poor Responders Intervention Trial (PRINT) Reprod Health 4 2007 12
    • (2007) Reprod Health , vol.4 , pp. 12
    • Sunkara, S.K.1    Coomarasamy, A.2    Khalaf, Y.3    Braude, P.4
  • 14
    • 3242880336 scopus 로고    scopus 로고
    • Defining poor ovarian response during IVF cycles, in women aged <40 years, and its relationship with treatment outcome
    • DOI 10.1093/humrep/deh273
    • C. Kailasam, S.D. Keay, P. Wilson, W.C.L. Ford, and J.M. Jenkins Defining poor ovarian response during IVF cycles, in women aged <40 years, and its relationship with treatment outcome Hum Reprod 19 2004 1544 1547 (Pubitemid 38997178)
    • (2004) Human Reproduction , vol.19 , Issue.7 , pp. 1544-1547
    • Kailasam, C.1    Keay, S.D.2    Wilson, P.3    Ford, W.C.L.4    Jenkins, J.M.5
  • 15
    • 15844371620 scopus 로고    scopus 로고
    • GnRH antagonist versus long GnRH agonist protocol in poor responders undergoing IVF: A randomized controlled trial
    • DOI 10.1093/humrep/deh668
    • L.P. Cheung, P.M. Lam, I.H. Lok, T.T. Chiu, S.Y. Yeung, and C.C. Tjer et al. GnRH antagonist versus long GnRH agonist protocol in poor responders undergoing IVF: a randomized controlled trial Hum Reprod 20 2005 616 621 (Pubitemid 40425485)
    • (2005) Human Reproduction , vol.20 , Issue.3 , pp. 616-621
    • Cheung, L.-P.1    Lam, P.-M.2    Lok, I.H.3    Chiu, T.T.-Y.4    Yeung, S.-Y.5    Tjer, C.-C.6    Haines, C.J.7
  • 16
    • 50049115549 scopus 로고    scopus 로고
    • Efficiency of follicle-stimulating hormone, commenced in the luteal phase, for overcoming a poor response in assisted reproduction
    • T. Kucuk, U. Goktolga, and E. Sozen Efficiency of follicle-stimulating hormone, commenced in the luteal phase, for overcoming a poor response in assisted reproduction J Obstet Gynaecol Res 34 2008 574 577
    • (2008) J Obstet Gynaecol Res , vol.34 , pp. 574-577
    • Kucuk, T.1    Goktolga, U.2    Sozen, E.3
  • 17
    • 77950903051 scopus 로고    scopus 로고
    • Interventions for "poor responders" to controlled ovarian hyper stimulation (COS) in in-vitro fertilisation (IVF)
    • Z. Pandian, A.R. McTavish, L. Aucott, M.P. Hamilton, and S. Bhattacharya Interventions for "poor responders" to controlled ovarian hyper stimulation (COS) in in-vitro fertilisation (IVF) Cochrane Database Systematic Rev 1 2010 CD004379
    • (2010) Cochrane Database Systematic Rev , vol.1 , pp. 004379
    • Pandian, Z.1    McTavish, A.R.2    Aucott, L.3    Hamilton, M.P.4    Bhattacharya, S.5
  • 18
    • 0025790271 scopus 로고
    • A randomized prospective study on the effect of short and long buserelin treatment in women with repeated unsuccessful in vitro fertilization (IVF) cycles due to inadequate ovarian response
    • M. Dirnfeld, Y. Gonen, A. Lissak, S. Goldman, M. Koifman, and Y. Sorokin A randomized prospective study on the effect of short and long buserelin treatment in women with repeated unsuccessful in vitro fertilization (IVF) cycles due to inadequate ovarian response J In Vitro Fert Embryo Transf 8 1991 339 343
    • (1991) J in Vitro Fert Embryo Transf , vol.8 , pp. 339-343
    • Dirnfeld, M.1    Gonen, Y.2    Lissak, A.3    Goldman, S.4    Koifman, M.5    Sorokin, Y.6
  • 19
    • 0037381367 scopus 로고    scopus 로고
    • Prospective evaluation of two stimulation protocols for low responders who were undergoing in vitro fertilization-embryo transfer
    • DOI 10.1016/S0015-0282(02)04928-2
    • A. Weissman, J. Farhi, M. Royburt, H. Nahum, M. Glezerman, and D. Levran Prospective evaluation of two stimulation protocols for low responders who were undergoing in vitro fertilization-embryo transfer Fertil Steril 79 2003 886 892 (Pubitemid 36385008)
    • (2003) Fertility and Sterility , vol.79 , Issue.4 , pp. 886-892
    • Weissman, A.1    Farhi, J.2    Royburt, M.3    Nahum, H.4    Glezerman, M.5    Levran, D.6
  • 20
    • 79959425612 scopus 로고    scopus 로고
    • A prospective, randomized comparison of two short stimulation protocols with agonist and antagonist of GnRH in poor responders patients undergoing IVF. Preliminary report. Abstracts of the 19th Annual Meeting of the ESHRE, Madrid, Spain
    • R. Marci, D. Caserta, M. Farina, S. Dessole, M. Germond, and C. Tatone et al. A prospective, randomized comparison of two short stimulation protocols with agonist and antagonist of GnRH in poor responders patients undergoing IVF. Preliminary report. Abstracts of the 19th Annual Meeting of the ESHRE, Madrid, Spain Hum Reprod 18 2003 113
    • (2003) Hum Reprod , vol.18 , pp. 113
    • Marci, R.1    Caserta, D.2    Farina, M.3    Dessole, S.4    Germond, M.5    Tatone, C.6
  • 21
    • 23744489576 scopus 로고    scopus 로고
    • Comparison of a gonadotropin-releasing hormone (GnRH) antagonist and GnRH agonist flare-up regimen in poor responders undergoing ovarian stimulation
    • DOI 10.1016/j.fertnstert.2005.01.139, PII S0015028205008976
    • S. Malmusi, M.A. La, S. Giulini, S. Xella, D. Tagliasacchi, and T. Marsella et al. Comparison of a gonadotropin-releasing hormone (GnRH) antagonist and GnRH agonist flare-up regimen in poor responders undergoing ovarian stimulation Fertil Steril 84 2005 402 406 (Pubitemid 41125261)
    • (2005) Fertility and Sterility , vol.84 , Issue.2 , pp. 402-406
    • Malmusi, S.1    La Marca, A.2    Giulini, S.3    Xella, S.4    Tagliasacchi, D.5    Marsella, T.6    Volpe, A.7
  • 22
    • 18144393122 scopus 로고    scopus 로고
    • A randomized prospective study of microdose leuprolide versus ganirelix in in vitro fertilization cycles for poor responders
    • DOI 10.1016/j.fertnstert.2004.10.053
    • D.W. Schmidt, T. Bremner, J.J. Orris, D.B. Maier, C.A. Benadiva, and J.C. Nulsen A randomized prospective study of microdose leuprolide versus ganirelix in in vitro fertilization cycles for poor responders Fertil Steril 83 2005 1568 1571 (Pubitemid 40615845)
    • (2005) Fertility and Sterility , vol.83 , Issue.5 , pp. 1568-1571
    • Schmidt, D.W.1    Bremner, T.2    Orris, J.J.3    Maier, D.B.4    Benadiva, C.A.5    Nulsen, J.C.6
  • 23
    • 37049008283 scopus 로고    scopus 로고
    • Comparing gonadotrophin-releasing hormone agonists or gonadotrophin-releasing hormone antagonists in poor responder in IVF
    • F. Aletebi Comparing gonadotrophin-releasing hormone agonists or gonadotrophin-releasing hormone antagonists in poor responder in IVF Middle East Fertil Soc J 12 2007 123 127
    • (2007) Middle East Fertil Soc J , vol.12 , pp. 123-127
    • Aletebi, F.1
  • 24
    • 67349086863 scopus 로고    scopus 로고
    • Microdose gonadotropin-releasing hormone agonist flare-up protocol versus multiple dose gonadotropin-releasing hormone antagonist protocol in poor responders undergoing intracytoplasmic sperm injection-embryo transfer cycle
    • K. Kahraman, B. Berker, C.S. Atabekoglu, M. Sonmezer, E. Cetinkaya, and R. Aytac et al. Microdose gonadotropin-releasing hormone agonist flare-up protocol versus multiple dose gonadotropin-releasing hormone antagonist protocol in poor responders undergoing intracytoplasmic sperm injection-embryo transfer cycle Fertil Steril 91 2009 2437 2444
    • (2009) Fertil Steril , vol.91 , pp. 2437-2444
    • Kahraman, K.1    Berker, B.2    Atabekoglu, C.S.3    Sonmezer, M.4    Cetinkaya, E.5    Aytac, R.6
  • 25
    • 44449134744 scopus 로고    scopus 로고
    • Flexible GnRH antagonist versus flare-up GnRH agonist protocol in poor responders treated by IVF: A randomized controlled trial
    • DOI 10.1093/humrep/den107
    • T.G. Lainas, I.A. Sfontouris, E.G. Papanikolaou, J.Z. Zorzovilis, G.K. Petsas, and G.T. Lainas et al. Flexible GnRH antagonist versus flare-up GnRH agonist protocol in poor responders treated by IVF: a randomized controlled trial Hum Reprod 23 2008 1355 1358 (Pubitemid 351770585)
    • (2008) Human Reproduction , vol.23 , Issue.6 , pp. 1355-1358
    • Lainas, T.G.1    Sfontouris, I.A.2    Papanikolaou, E.G.3    Zorzovilis, J.Z.4    Petsas, G.K.5    Lainas, G.T.6    Kolibianakis, E.M.7
  • 27
    • 51449118412 scopus 로고    scopus 로고
    • Comparison of multiple dose GnRH antagonist and minidose long agonist protocols in poor responders undergoing in vitro fertilization: A randomized controlled trial
    • A. Tazegul, H. Gorkemli, S. Ozdemir, and T.M. Aktan Comparison of multiple dose GnRH antagonist and minidose long agonist protocols in poor responders undergoing in vitro fertilization: a randomized controlled trial Arch Gynecol Obstet 278 2008 467 472
    • (2008) Arch Gynecol Obstet , vol.278 , pp. 467-472
    • Tazegul, A.1    Gorkemli, H.2    Ozdemir, S.3    Aktan, T.M.4
  • 28
    • 67649448876 scopus 로고    scopus 로고
    • Flexible, multi-dose GnRH antagonist versus long GnRH agonist protocol in poor responders: A randomized controlled trial
    • E.S. Tehraninejad, A. Fazel, A. Samiei, B. Rashidi, and K. Kiani Flexible, multi-dose GnRH antagonist versus long GnRH agonist protocol in poor responders: a randomized controlled trial Int J Fertil Steril 2 2009 165 168
    • (2009) Int J Fertil Steril , vol.2 , pp. 165-168
    • Tehraninejad, E.S.1    Fazel, A.2    Samiei, A.3    Rashidi, B.4    Kiani, K.5
  • 29
    • 33751116124 scopus 로고    scopus 로고
    • GnRH-antagonists in ovarian stimulation for IVF in patients with poor response to gonadotrophins, polycystic ovary syndrome, and risk of ovarian hyperstimulation: A meta-analysis
    • 2432
    • G. Griesinger, K. Diedrich, B.C. Tarlatzis, and E.M. Kolibianakis GnRH-antagonists in ovarian stimulation for IVF in patients with poor response to gonadotrophins, polycystic ovary syndrome, and risk of ovarian hyperstimulation: a meta-analysis Reprod Biomed Online 13 2006 628 638 (Pubitemid 44760885)
    • (2006) Reproductive BioMedicine Online , vol.13 , Issue.5 , pp. 628-638
    • Griesinger, G.1    Diedrich, K.2    Tarlatzis, B.C.3    Kolibianakis, E.M.4
  • 30
    • 80052870242 scopus 로고    scopus 로고
    • Comparison of GnRH antagonist versus GnRH agonist protocol in poor ovarian responders undergoing IVF
    • D. Pu, J. Wu, and J. Liu Comparison of GnRH antagonist versus GnRH agonist protocol in poor ovarian responders undergoing IVF Hum Reprod 26 2011 2742 2749
    • (2011) Hum Reprod , vol.26 , pp. 2742-2749
    • Pu, D.1    Wu, J.2    Liu, J.3
  • 31
    • 84856079535 scopus 로고    scopus 로고
    • Comparison of different stimulation protocols efficacy in poor responders undergoing IVF: A retrospective study
    • T. Madani, M. Asrafi, and L.M. Yeganeh Comparison of different stimulation protocols efficacy in poor responders undergoing IVF: a retrospective study Gynaecol Endocrinol 28 2012 102 105
    • (2012) Gynaecol Endocrinol , vol.28 , pp. 102-105
    • Madani, T.1    Asrafi, M.2    Yeganeh, L.M.3
  • 32
    • 0037336738 scopus 로고    scopus 로고
    • Women older than 40 years of age and those with elevated follicle-stimulating hormone levels differ in poor response rate and embryo quality in in vitro fertilization
    • DOI 10.1016/S0015-0282(02)04839-2
    • I.A. van Rooij, L.F. Bancsi, F.J. Broekmans, C.W. Looman, J.D. Habbema, and E.R. te Velde Women older than 40 years of age and those with elevated follicle-stimulating hormone levels differ in poor response rate and embryo quality in in vitro fertilization Fertil Steril 79 2003 482 488 (Pubitemid 36293437)
    • (2003) Fertility and Sterility , vol.79 , Issue.3 , pp. 482-488
    • Van Rooij, I.A.J.1    Bancsi, L.F.J.M.M.2    Broekmans, F.J.M.3    Looman, C.W.N.4    Habbema, J.D.F.5    Te Velde, E.R.6
  • 33
    • 33750220064 scopus 로고    scopus 로고
    • A systematic review of tests predicting ovarian reserve and IVF outcome
    • DOI 10.1093/humupd/dml034
    • F.J. Broekmans, J. Kwee, D.J. Hendriks, B.W. Mol, and C.B. Lambalk A systematic review of tests predicting ovarian reserve and IVF outcome Hum Reprod Update 12 2006 685 718 (Pubitemid 44605509)
    • (2006) Human Reproduction Update , vol.12 , Issue.6 , pp. 685-718
    • Broekmans, F.J.1    Kwee, J.2    Hendriks, D.J.3    Mol, B.W.4    Lambalk, C.B.5
  • 34
    • 0026655467 scopus 로고
    • The prognostic importance of the number of oocytes retrieved and estradiol levels in poor and normal responders in in vitro fertilization (IVF) treatment
    • J. Dor, D.S. Seidman, I. Ben-Shlomo, D. Levran, A. Karasik, and S. Mashiach The prognostic importance of the number of oocytes retrieved and estradiol levels in poor and normal responders in in vitro fertilization (IVF) treatment J Assist Reprod Genet 9 1992 228 232
    • (1992) J Assist Reprod Genet , vol.9 , pp. 228-232
    • Dor, J.1    Seidman, D.S.2    Ben-Shlomo, I.3    Levran, D.4    Karasik, A.5    Mashiach, S.6
  • 35
    • 79959426436 scopus 로고    scopus 로고
    • ESHRE consensus on the definition of "poor response" to ovarian stimulation for in vitro fertilization: The Bologna criteria
    • A.P. Ferraretti, A. La Marca, B.J.M. Fauser, B. Tarlatzis, G. Nargund, and L. Gianaroli ESHRE consensus on the definition of "poor response" to ovarian stimulation for in vitro fertilization: the Bologna criteria Hum Reprod 26 2011 1616 1624
    • (2011) Hum Reprod , vol.26 , pp. 1616-1624
    • Ferraretti, A.P.1    La Marca, A.2    Fauser, B.J.M.3    Tarlatzis, B.4    Nargund, G.5    Gianaroli, L.6
  • 36
    • 0028266338 scopus 로고
    • Early follicular rise of serum progesterone concentration in response to a flare-up effect of gonadotrophin-releasing hormone agonist impairs follicular recruitment for in-vitro fertilization
    • J.A. Sims, H.J. Seltman, and S.J. Muasher Early follicular rise of serum progesterone concentration in response to flare-up effect of gonadotrophin-releasing hormone agonist impairs follicular recruitment for in-vitro fertilization Hum Reprod 9 1994 235 240 (Pubitemid 24076743)
    • (1994) Human Reproduction , vol.9 , Issue.2 , pp. 235-240
    • Sims, J.A.1    Seltman, H.J.2    Muasher, S.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.