메뉴 건너뛰기




Volumn 306, Issue 1, 2014, Pages

Postprandial VLDL lipolysis products increase monocyte adhesion and lipid droplet formation via activation of ERK2 and NFκB

Author keywords

Adhesion molecules; Fatty acids; Inflammation; Lipoprotein lipase

Indexed keywords

BETA1 INTEGRIN; CD11B ANTIGEN; CD18 ANTIGEN; FAT DROPLET; GLYCOPROTEIN P 15095; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 8; LIPOPROTEIN LIPASE; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN KINASE B; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; VERY LATE ACTIVATION ANTIGEN 4; VERY LOW DENSITY LIPOPROTEIN;

EID: 84891547459     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00137.2013     Document Type: Article
Times cited : (38)

References (42)
  • 1
    • 1542374060 scopus 로고    scopus 로고
    • Signal transduction via the NF-kappaB pathway: A targeted treatment modality for infection, inflammation and repair
    • Ali S, Mann DA. Signal transduction via the NF-kappaB pathway: a targeted treatment modality for infection, inflammation and repair. Cell Biochem Funct 22: 67-79, 2004.
    • (2004) Cell Biochem Funct , vol.22 , pp. 67-79
    • Ali, S.1    Mann, D.A.2
  • 3
    • 84883304683 scopus 로고    scopus 로고
    • Induction of ATF3 gene network by triglyceride-rich lipoprotein lipolysis products increases vascular apoptosis and inflammation
    • Aung HH, Lame MW, Gohil K, An CI, Wilson DW, Rutledge JC. Induction of ATF3 gene network by triglyceride-rich lipoprotein lipolysis products increases vascular apoptosis and inflammation. Arterioscler Thromb Vasc Biol 33: 2088-2096, 2013.
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , pp. 2088-2096
    • Aung, H.H.1    Lame, M.W.2    Gohil, K.3    An, C.I.4    Wilson, D.W.5    Rutledge, J.C.6
  • 5
    • 74049139572 scopus 로고    scopus 로고
    • Postprandial dietary lipid-specific effects on human peripheral blood mononuclear cell gene expression profiles
    • Bouwens M, Grootte Bromhaar M, Jansen J, Müller M, Afman LA. Postprandial dietary lipid-specific effects on human peripheral blood mononuclear cell gene expression profiles. Am J Clin Nutr 91: 208-217, 2010.
    • (2010) Am J Clin Nutr , vol.91 , pp. 208-217
    • Bouwens, M.1    Grootte Bromhaar, M.2    Jansen, J.3    Müller, M.4    Afman, L.A.5
  • 6
    • 77951639826 scopus 로고    scopus 로고
    • Fatty acids from very low-density lipoprotein lipolysis products induce lipid droplet accumulation in human monocytes
    • den Hartigh LJ, Connolly-Rohrbach JE, Fore S, Huser TR, Rutledge JC. Fatty acids from very low-density lipoprotein lipolysis products induce lipid droplet accumulation in human monocytes. J Immunol 184: 3927-3936, 2010.
    • (2010) J Immunol , vol.184 , pp. 3927-3936
    • den Hartigh, L.J.1    Connolly-Rohrbach, J.E.2    Fore, S.3    Huser, T.R.4    Rutledge, J.C.5
  • 8
    • 34249324303 scopus 로고    scopus 로고
    • Lipolysis products from triglyceride-rich lipoproteins increase endothelial permeability, perturb zonula occludens-1 and F-actin, and induce apoptosis
    • Eiselein L, Wilson DW, Lamé MW, Rutledge JC. Lipolysis products from triglyceride-rich lipoproteins increase endothelial permeability, perturb zonula occludens-1 and F-actin, and induce apoptosis. Am J Physiol Heart Circ Physiol 292: H2745-H2753, 2007.
    • (2007) Am J Physiol Heart Circ Physiol , vol.292
    • Eiselein, L.1    Wilson, D.W.2    Lamé, M.W.3    Rutledge, J.C.4
  • 10
    • 0036839228 scopus 로고    scopus 로고
    • Inflammation and immune responses in atherosclerosis
    • Greaves DR, Channon KM. Inflammation and immune responses in atherosclerosis. Trends Immunol 23: 535-541, 2002.
    • (2002) Trends Immunol , vol.23 , pp. 535-541
    • Greaves, D.R.1    Channon, K.M.2
  • 11
    • 84867341619 scopus 로고    scopus 로고
    • Simultaneous activation of p38 and JNK by arachidonic acid stimulates the cytosolic phospholipase A2-dependent synthesis of lipid droplets in human monocytes
    • Guijas C, Pérez-Chacón G, Astudillo AM, Rubio JM, Gil-de-Gómez L, Balboa MA, Balsinde J. Simultaneous activation of p38 and JNK by arachidonic acid stimulates the cytosolic phospholipase A2-dependent synthesis of lipid droplets in human monocytes. J Lipid Res 53: 2343-2354, 2012.
    • (2012) J Lipid Res , vol.53 , pp. 2343-2354
    • Guijas, C.1    Pérez-Chacón, G.2    Astudillo, A.M.3    Rubio, J.M.4    Gil-de-Gómez, L.5    Balboa, M.A.6    Balsinde, J.7
  • 13
    • 12344252237 scopus 로고    scopus 로고
    • AP-1 subunits: Quarrel and harmony among siblings
    • Hess J, Angel P, Schorpp-Kistner M. AP-1 subunits: quarrel and harmony among siblings. J Cell Sci 117: 5965-5973, 2004.
    • (2004) J Cell Sci , vol.117 , pp. 5965-5973
    • Hess, J.1    Angel, P.2    Schorpp-Kistner, M.3
  • 14
    • 65449131608 scopus 로고    scopus 로고
    • Inflammation associated with the postprandial lipolysis of triglyceride-rich lipoproteins by lipoprotein lipase
    • Higgins LJ, Rutledge JC. Inflammation associated with the postprandial lipolysis of triglyceride-rich lipoproteins by lipoprotein lipase. Curr Atheroscler Rep 11: 199-205, 2009.
    • (2009) Curr Atheroscler Rep , vol.11 , pp. 199-205
    • Higgins, L.J.1    Rutledge, J.C.2
  • 15
    • 0026770377 scopus 로고
    • Integrins: Versatility, modulation, and signaling in cell adhesion
    • Hynes RO. Integrins: versatility, modulation, and signaling in cell adhesion. Cell 69: 11-25, 1992.
    • (1992) Cell , vol.69 , pp. 11-25
    • Hynes, R.O.1
  • 16
    • 0035992611 scopus 로고    scopus 로고
    • Postprandial lipemia is associated with platelet and monocyte activation and increased monocyte cytokine expression in normolipemic men
    • Hyson DA, Paglieroni TG, Wun T, Rutledge JC. Postprandial lipemia is associated with platelet and monocyte activation and increased monocyte cytokine expression in normolipemic men. Clin Appl Thromb Hemost 8: 147-155, 2002.
    • (2002) Clin Appl Thromb Hemost , vol.8 , pp. 147-155
    • Hyson, D.A.1    Paglieroni, T.G.2    Wun, T.3    Rutledge, J.C.4
  • 17
    • 58549105701 scopus 로고    scopus 로고
    • Induction of proinflammatory cytokines by long-chain saturated fatty acids in human macrophages
    • Håversen L, Danielsson KN, Fogelstrand L, Wiklund O. Induction of proinflammatory cytokines by long-chain saturated fatty acids in human macrophages. Atherosclerosis 202: 382-393, 2009.
    • (2009) Atherosclerosis , vol.202 , pp. 382-393
    • Håversen, L.1    Danielsson, K.N.2    Fogelstrand, L.3    Wiklund, O.4
  • 18
    • 33751331444 scopus 로고    scopus 로고
    • Activating transcription factor 3 (ATF3) represses the expression of CCL4 in murine macrophages
    • Khuu CH, Barrozo RM, Hai T, Weinstein SL. Activating transcription factor 3 (ATF3) represses the expression of CCL4 in murine macrophages. Mol Immunol 44: 1598-1605, 2007.
    • (2007) Mol Immunol , vol.44 , pp. 1598-1605
    • Khuu, C.H.1    Barrozo, R.M.2    Hai, T.3    Weinstein, S.L.4
  • 19
    • 0016176637 scopus 로고
    • Selective measurement of two lipase activities in postheparin plasma from normal subjects and patients with hyperlipoproteinemia
    • Krauss RM, Levy RI, Fredrickson DS. Selective measurement of two lipase activities in postheparin plasma from normal subjects and patients with hyperlipoproteinemia. J Clin Invest 54: 1107-1124, 1974.
    • (1974) J Clin Invest , vol.54 , pp. 1107-1124
    • Krauss, R.M.1    Levy, R.I.2    Fredrickson, D.S.3
  • 20
    • 38149034276 scopus 로고    scopus 로고
    • TNF-alpha induction by Pseudomonas aeruginosa lipopolysaccharide or slime-glycolipoprotein in human monocytes is regulated at the level of Mitogen-activated Protein Kinase activity: A distinct role of Toll-like receptor 2 and 4
    • Lagoumintzis G, Xaplanteri P, Dimitracopoulos G, Paliogianni F. TNF-alpha induction by Pseudomonas aeruginosa lipopolysaccharide or slime-glycolipoprotein in human monocytes is regulated at the level of Mitogen-activated Protein Kinase activity: a distinct role of Toll-like receptor 2 and 4. Scand J Immunol 67: 193-203, 2008.
    • (2008) Scand J Immunol , vol.67 , pp. 193-203
    • Lagoumintzis, G.1    Xaplanteri, P.2    Dimitracopoulos, G.3    Paliogianni, F.4
  • 22
    • 0035907302 scopus 로고    scopus 로고
    • Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4
    • Lee JY, Sohn KH, Rhee SH, Hwang D. Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4. J Biol Chem 276: 16683-16689, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 16683-16689
    • Lee, J.Y.1    Sohn, K.H.2    Rhee, S.H.3    Hwang, D.4
  • 23
    • 0141844653 scopus 로고    scopus 로고
    • Reciprocal modulation of Toll-like receptor-4 signaling pathways involving MyD88 and phosphatidylinositol 3-kinase/AKT by saturated and polyunsaturated fatty acids
    • Lee JY, Ye J, Gao Z, Youn HS, Lee WH, Zhao L, Sizemore N, Hwang DH. Reciprocal modulation of Toll-like receptor-4 signaling pathways involving MyD88 and phosphatidylinositol 3-kinase/AKT by saturated and polyunsaturated fatty acids. J Biol Chem 278: 37041-37051, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 37041-37051
    • Lee, J.Y.1    Ye, J.2    Gao, Z.3    Youn, H.S.4    Lee, W.H.5    Zhao, L.6    Sizemore, N.7    Hwang, D.H.8
  • 24
    • 0037036421 scopus 로고    scopus 로고
    • Dynamic regulation of LFA-1 activation and neutrophil arrest on intercellular adhesion molecule 1 (ICAM-1) in shear flow
    • Lum AF, Green CE, Lee GR, Staunton DE, Simon SI. Dynamic regulation of LFA-1 activation and neutrophil arrest on intercellular adhesion molecule 1 (ICAM-1) in shear flow. J Biol Chem 277: 20660-20670, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 20660-20670
    • Lum, A.F.1    Green, C.E.2    Lee, G.R.3    Staunton, D.E.4    Simon, S.I.5
  • 25
    • 84860887556 scopus 로고    scopus 로고
    • Linoleic acid increases monocyte chemotaxis and adhesion to human aortic endothelial cells through protein kinase C-and cyclooxygenase-2-dependent mechanisms
    • Matesanz N, Jewhurst V, Trimble ER, McGinty A, Owens D, Tomkin GH, Powell LA. Linoleic acid increases monocyte chemotaxis and adhesion to human aortic endothelial cells through protein kinase C-and cyclooxygenase-2-dependent mechanisms. J Nutr Biochem 23: 685-690, 2012.
    • (2012) J Nutr Biochem , vol.23 , pp. 685-690
    • Matesanz, N.1    Jewhurst, V.2    Trimble, E.R.3    McGinty, A.4    Owens, D.5    Tomkin, G.H.6    Powell, L.A.7
  • 26
    • 0038771263 scopus 로고    scopus 로고
    • Gene expression and intracellular pathways involved in endothelial dysfunction induced by VLDL and oxidised VLDL
    • Norata GD, Pirillo A, Callegari E, Hamsten A, Catapano AL, Eriksson P. Gene expression and intracellular pathways involved in endothelial dysfunction induced by VLDL and oxidised VLDL. Cardiovasc Res 59: 169-180, 2003.
    • (2003) Cardiovasc Res , vol.59 , pp. 169-180
    • Norata, G.D.1    Pirillo, A.2    Callegari, E.3    Hamsten, A.4    Catapano, A.L.5    Eriksson, P.6
  • 27
    • 1842867217 scopus 로고    scopus 로고
    • Expression of the myeloid-specific leukocyte integrin gene CD11d during macrophage foam cell differentiation and exposure to lipoproteins
    • Noti JD. Expression of the myeloid-specific leukocyte integrin gene CD11d during macrophage foam cell differentiation and exposure to lipoproteins. Int J Mol Med 10: 721-727, 2002.
    • (2002) Int J Mol Med , vol.10 , pp. 721-727
    • Noti, J.D.1
  • 28
    • 0141639811 scopus 로고    scopus 로고
    • Role of monocytes in atherogenesis
    • Osterud B, Bjorklid E. Role of monocytes in atherogenesis. Physiol Rev 83: 1069-1112, 2003.
    • (2003) Physiol Rev , vol.83 , pp. 1069-1112
    • Osterud, B.1    Bjorklid, E.2
  • 30
    • 0032693599 scopus 로고    scopus 로고
    • Atherosclerosis is an inflammatory disease
    • Ross R. Atherosclerosis is an inflammatory disease. Am Heart J 138: S419-420, 1999.
    • (1999) Am Heart J , vol.138
    • Ross, R.1
  • 31
    • 77956636092 scopus 로고    scopus 로고
    • Role of triglyceride-rich lipoproteins in diabetic nephropathy
    • Rutledge JC, Ng KF, Aung HH, Wilson DW. Role of triglyceride-rich lipoproteins in diabetic nephropathy. Nat Rev Nephrol 6: 361-370, 2010.
    • (2010) Nat Rev Nephrol , vol.6 , pp. 361-370
    • Rutledge, J.C.1    Ng, K.F.2    Aung, H.H.3    Wilson, D.W.4
  • 32
    • 0027051792 scopus 로고
    • Lipoprotein lipasemediated lipolysis of very low density lipoproteins increases monocyte adhesion to aortic endothelial cells
    • Saxena U, Kulkarni NM, Ferguson E, Newton RS. Lipoprotein lipasemediated lipolysis of very low density lipoproteins increases monocyte adhesion to aortic endothelial cells. Biochem Biophys Res Commun 189: 1653-1658, 1992.
    • (1992) Biochem Biophys Res Commun , vol.189 , pp. 1653-1658
    • Saxena, U.1    Kulkarni, N.M.2    Ferguson, E.3    Newton, R.S.4
  • 35
    • 84860480643 scopus 로고    scopus 로고
    • Moderate-intensity, premeal cycling blunts postprandial increases in monocyte cell surface CD18 and CD11a and endothelial microparticles following a high-fat meal in young adults
    • Strohacker K, Breslin WL, Carpenter KC, Davidson TR, Agha NH, McFarlin BK. Moderate-intensity, premeal cycling blunts postprandial increases in monocyte cell surface CD18 and CD11a and endothelial microparticles following a high-fat meal in young adults. Appl Physiol Nutr Metab 37: 530-539, 2012.
    • (2012) Appl Physiol Nutr Metab , vol.37 , pp. 530-539
    • Strohacker, K.1    Breslin, W.L.2    Carpenter, K.C.3    Davidson, T.R.4    Agha, N.H.5    McFarlin, B.K.6
  • 36
    • 0026321462 scopus 로고
    • Kupffer cell-derived cytokines induce the synthesis of a leukocyte chemotactic peptide, interleukin-8, in human hepatoma and primary hepatocyte cultures
    • Thornton AJ, Ham J, Kunkel SL. Kupffer cell-derived cytokines induce the synthesis of a leukocyte chemotactic peptide, interleukin-8, in human hepatoma and primary hepatocyte cultures. Hepatology 14: 1112-1122, 1991.
    • (1991) Hepatology , vol.14 , pp. 1112-1122
    • Thornton, A.J.1    Ham, J.2    Kunkel, S.L.3
  • 37
    • 33847010885 scopus 로고    scopus 로고
    • Triglyceride-rich lipoproteins prime aortic endothelium for an enhanced inflammatory response to tumor necrosis factor-alpha
    • Ting HJ, Stice JP, Schaff UY, Hui DY, Rutledge JC, Knowlton AA, Passerini AG, Simon SI. Triglyceride-rich lipoproteins prime aortic endothelium for an enhanced inflammatory response to tumor necrosis factor-alpha. Circ Res 100: 381-390, 2007.
    • (2007) Circ Res , vol.100 , pp. 381-390
    • Ting, H.J.1    Stice, J.P.2    Schaff, U.Y.3    Hui, D.Y.4    Rutledge, J.C.5    Knowlton, A.A.6    Passerini, A.G.7    Simon, S.I.8
  • 38
    • 0029068239 scopus 로고
    • Transcriptional activation of the human TNF-alpha promoter by superantigen in human monocytic cells: Role of NF-kappa B
    • Trede NS, Tsytsykova AV, Chatila T, Goldfeld AE, Geha RS. Transcriptional activation of the human TNF-alpha promoter by superantigen in human monocytic cells: role of NF-kappa B. J Immunol 155: 902-908, 1995.
    • (1995) J Immunol , vol.155 , pp. 902-908
    • Trede, N.S.1    Tsytsykova, A.V.2    Chatila, T.3    Goldfeld, A.E.4    Geha, R.S.5
  • 40
    • 64749100482 scopus 로고    scopus 로고
    • Triglyceride-rich lipoprotein lipolysis releases neutral and oxidized FFAs that induce endothelial cell inflammation
    • Wang L, Gill R, Pedersen TL, Higgins LJ, Newman JW, Rutledge JC. Triglyceride-rich lipoprotein lipolysis releases neutral and oxidized FFAs that induce endothelial cell inflammation. J Lipid Res 50: 204-213, 2009.
    • (2009) J Lipid Res , vol.50 , pp. 204-213
    • Wang, L.1    Gill, R.2    Pedersen, T.L.3    Higgins, L.J.4    Newman, J.W.5    Rutledge, J.C.6
  • 41
    • 45949095352 scopus 로고    scopus 로고
    • Osteoblasts-derived TGF-beta1 enhance motility and integrin upregulation through Akt, ERK, and NF-kappaB-dependent pathway in human breast cancer cells
    • Wei YY, Chen YJ, Hsiao YC, Huang YC, Lai TH, Tang CH. Osteoblasts-derived TGF-beta1 enhance motility and integrin upregulation through Akt, ERK, and NF-kappaB-dependent pathway in human breast cancer cells. Mol Carcinog 47: 526-537, 2008.
    • (2008) Mol Carcinog , vol.47 , pp. 526-537
    • Wei, Y.Y.1    Chen, Y.J.2    Hsiao, Y.C.3    Huang, Y.C.4    Lai, T.H.5    Tang, C.H.6
  • 42
    • 0015761961 scopus 로고
    • A proposal linking atherogenesis to the interaction of endothelial lipoprotein lipase with triglyceride-rich lipoproteins
    • Zilversmit DB. A proposal linking atherogenesis to the interaction of endothelial lipoprotein lipase with triglyceride-rich lipoproteins. Circ Res 33: 633-638, 1973.
    • (1973) Circ Res , vol.33 , pp. 633-638
    • Zilversmit, D.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.