SCOPUS 정보 검색 플랫폼

Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 1, 2014, Pages 280-282

High-throughput docking for the identification of new influenza A virus polymerase inhibitors targeting the PA-PB1 protein-protein interaction

(7) Tintori, Cristina a Laurenzana, Ilaria b Fallacara, Anna Lucia a,c Kessler, Ulrich d Pilger, Beatrice d Stergiou, Lilli d Botta, Maurizio a,e

a UNIVERSITY OF SIENA (Italy)

b REFERRAL CANCER CENTER OF BASILICATA (Italy)

c SAPIENZA UNIVERSITY OF ROME (Italy)

d ETH ZURICH (Switzerland)

e TEMPLE UNIVERSITY (United States)

Author keywords

Antiviral agents; High throughput docking; Influenza virus; PA PB1 interaction; Viral RNA polymerase; Virtual screening

Indexed keywords

3 CYANO 4,6 DIPHENYLPYRIDINE DERIVATIVE; AG 690; ANTIVIRUS AGENT; ASN 01054154; ASN 01157620; ASN 01213501; BAS 00801667; BAS 01157570; ENZYME INHIBITOR; PROTEIN PA; PROTEIN PB1; RNA POLYMERASE; STK 670561; UNCLASSIFIED DRUG; VIRUS PROTEIN; 3 CYANO 4,6 DIPHENYL PYRIDINE DERIVATIVE; AG 690 40750299; PA PROTEIN; PB1 PROTEIN; PYRIDINE DERIVATIVE; RNA DIRECTED RNA POLYMERASE INHIBITOR; VIRUS RNA;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CYTOTOXICITY; DRUG TARGETING; ENZYME LINKED IMMUNOSORBENT ASSAY; HIGH THROUGHPUT SCREENING; HYDROGEN BOND; HYDROPHOBICITY; IC 50; INFLUENZA VIRUS A; MDCK CELL; MOLECULAR DOCKING; MOLECULAR DYNAMICS; NONHUMAN; PROTEIN PROTEIN INTERACTION; BINDING AFFINITY; DRUG IDENTIFICATION; DRUG PROTEIN BINDING; ENZYME INHIBITION; IC50; IN VITRO STUDY; PROTEIN TARGETING;

INFLUENZA A VIRUS; ORTHOMYXOVIRIDAE;

ANTIVIRAL AGENTS; HIGH-THROUGHPUT DOCKING; INFLUENZA VIRUS; PA-PB1 INTERACTION; VIRAL RNA POLYMERASE; VIRTUAL SCREENING;

DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HIGH-THROUGHPUT SCREENING ASSAYS; INFLUENZA A VIRUS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTEIN BINDING; PYRIDINES; RNA REPLICASE; STRUCTURE-ACTIVITY RELATIONSHIP; VIRAL PROTEINS;

EID: 84891492237 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2013.11.019 Document Type: Article

Times cited : (31)

References (20)

1
- 34447299235
- B.N. Fields, D.M. Knipe, P.M. Howley, Wolters Kluwer Health/Lippincott Williams Wilkins Philadelphia
- P. Palese, and M. Shaw B.N. Fields, D.M. Knipe, P.M. Howley, Field's Virology vol. 2 2007 Wolters Kluwer Health/Lippincott Williams Wilkins Philadelphia 1647 1689
- (2007) Field's Virology , vol.2 VOL. , pp. 1647-1689
- Palese, P.¹ Shaw, M.²

2
- 34548611066
- F. Carrat, and A. Flahault Vaccine 25 2007 6852
- (2007) Vaccine , vol.25 , pp. 6852
- Carrat, F.¹ Flahault, A.²

3
- 0346688614
- J. Treanor N. Eng. J. Med. 350 218-220 2004 4
- (2004) N. Eng. J. Med. , vol.350 , Issue.218-220 , pp. 4
- Treanor, J.¹

4
- 0344395604
- R.J. Webby, and R.G. Webster Science 302 2003 1519
- (2003) Science , vol.302 , pp. 1519
- Webby, R.J.¹ Webster, R.G.²

5
- 65649085213
- M. Michaelis, H.W. Doerr, and J. Cinatl Jr. Curr. Mol. Med. 9 2009 131
- (2009) Curr. Mol. Med. , vol.9 , pp. 131
- Michaelis, M.¹ Doerr, H.W.² Cinatl, Jr.J.³

6
- 36749056771
- M. von Itzstein Nat. Rev. Drug Disc. 6 2007 967
- (2007) Nat. Rev. Drug Disc. , vol.6 , pp. 967
- Von Itzstein, M.¹

7
- 36949001617
- H.P. Hsieh, and J.T. Hsu Curr. Pharm. Des. 13 2007 3531
- (2007) Curr. Pharm. Des. , vol.13 , pp. 3531
- Hsieh, H.P.¹ Hsu, J.T.²

8
- 33751517736
- E. De Clercq Nat. Rev. Drug Disc. 5 2006 1015
- (2006) Nat. Rev. Drug Disc. , vol.5 , pp. 1015
- De Clercq, E.¹

9
- 27144468290
- Q.M. Le, M. Kiso, K. Someya, Y.T. Sakai, T.H. Nguyen, K.H. Nguyen, N.D. Pham, H.H. Ngyen, S. Yamada, Y. Muramoto, T. Horimoto, A. Takada, H. Goto, T. Suzuki, Y. Suzuki, and Y. Kawaoka Nature 437 2005 1108
- (2005) Nature , vol.437 , pp. 1108
- Le, Q.M.¹ Kiso, M.² Someya, K.³ Sakai, Y.T.⁴ Nguyen, T.H.⁵ Nguyen, K.H.⁶ Pham, N.D.⁷ Ngyen, H.H.⁸ Yamada, S.⁹ Muramoto, Y.¹⁰ Horimoto, T.¹¹ Takada, A.¹² Goto, H.¹³ Suzuki, T.¹⁴ Suzuki, Y.¹⁵ Kawaoka, Y.¹⁶

10
- 29144528757
- M.D. DeJong, T.T. Tran, H.K. Truong, M.H. Vo, G.J. Smith, V.C. Nguyen, V.C. Bach, T.Q. Phan, Q.H. Do, Y. Guan, J.S. Peiris, T.H. Tran, and J. Farrar N. Eng. J. Med. 353 2005 2667
- (2005) N. Eng. J. Med. , vol.353 , pp. 2667
- Dejong, M.D.¹ Tran, T.T.² Truong, H.K.³ Vo, M.H.⁴ Smith, G.J.⁵ Nguyen, V.C.⁶ Bach, V.C.⁷ Phan, T.Q.⁸ Do, Q.H.⁹ Guan, Y.¹⁰ Peiris, J.S.¹¹ Tran, T.H.¹² Farrar, J.¹³

11
- 50649089174
- X. He, J. Zhou, M. Bartlam, R. Zhang, J. Ma, Z. Lou, X. Li, J. Li, A. Joachimiak, Z. Zeng, R. Ge, Z. Rao, and Y. Liu Nature 454 2008 1123
- (2008) Nature , vol.454 , pp. 1123
- He, X.¹ Zhou, J.² Bartlam, M.³ Zhang, R.⁴ Ma, J.⁵ Lou, Z.⁶ Li, X.⁷ Li, J.⁸ Joachimiak, A.⁹ Zeng, Z.¹⁰ Ge, R.¹¹ Rao, Z.¹² Liu, Y.¹³

12
- 50649122962
- E. Obayashi, H. Yoshida, F. Kawai, N. Shibayama, A. Kawaguchi, K. Nagata, J.R. Tame, and S.Y. Park Nature 454 2008 1127
- (2008) Nature , vol.454 , pp. 1127
- Obayashi, E.¹ Yoshida, H.² Kawai, F.³ Shibayama, N.⁴ Kawaguchi, A.⁵ Nagata, K.⁶ Tame, J.R.⁷ Park, S.Y.⁸

13
- 84884288993
- U. Kessler, D. Castagnolo, M. Pagano, D. Deodato, M. Bernardini, B. Pilger, C. Ranadheera, and M. Botta Bioorg. Med. Chem. Lett. 23 2013 5575
- (2013) Bioorg. Med. Chem. Lett. , vol.23 , pp. 5575
- Kessler, U.¹ Castagnolo, D.² Pagano, M.³ Deodato, D.⁴ Bernardini, M.⁵ Pilger, B.⁶ Ranadheera, C.⁷ Botta, M.⁸

14
- 84891491054
- accepted for publication
- Castagnolo, D.; Pagano, M.; Fallacara, A. L.; Laurenzana, I.; Deodato, D.; Kessler, U.; Pilger, B.; Stergiou, L.; Strunze, S.; Tintori, C.; Botta, M. ChemMedChem. (accepted for publication).
- ChemMedChem.
- Castagnolo, D.¹ Pagano, M.² Fallacara, A.L.³ Laurenzana, I.⁴ Deodato, D.⁵ Kessler, U.⁶ Pilger, B.⁷ Stergiou, L.⁸ Strunze, S.⁹ Tintori, C.¹⁰ Botta, M.¹¹

15
- 78751681564
- K. Wunderlich, M. Juozapaitis, C. Ranadheera, U. Kessler, A. Martin, J. Eisel, U. Beutling, R. Frank, and M. Schwemmle Antimicrob. Agents Chemother. 55 2011 696
- (2011) Antimicrob. Agents Chemother. , vol.55 , pp. 696
- Wunderlich, K.¹ Juozapaitis, M.² Ranadheera, C.³ Kessler, U.⁴ Martin, A.⁵ Eisel, J.⁶ Beutling, U.⁷ Frank, R.⁸ Schwemmle, M.⁹

16
- 77949825974
- Schrödinger New York, NY
- Glide, Version 5.5 2009 Schrödinger New York, NY
- (2009) Glide, Version 5.5

17
- 0041919542
- M.L. Verdonk, J.C. Cole, M.J. Hartshorn, C.W. Murray, and R.D. Taylor Proteins 52 2003 609
- (2003) Proteins , vol.52 , pp. 609
- Verdonk, M.L.¹ Cole, J.C.² Hartshorn, M.J.³ Murray, C.W.⁴ Taylor, R.D.⁵

18
- 80055072231
- G. Chase, K. Wunderlich, P. Reuther, and M. Schwemmle Methods 55 2011 188
- (2011) Methods , vol.55 , pp. 188
- Chase, G.¹ Wunderlich, K.² Reuther, P.³ Schwemmle, M.⁴

19
- 84859986406
- G. Muratore, L. Goracci, B. Mercorelli, Á. Foeglein, P. Digard, G. Cruciani, G. Palù, and A. Loregian Proc. Natl. Acad. Sci. U.S.A. 109 2012 6247
- (2012) Proc. Natl. Acad. Sci. U.S.A. , vol.109 , pp. 6247
- Muratore, G.¹ Goracci, L.² Mercorelli, B.³ Foeglein, Á.⁴ Digard, P.⁵ Cruciani, G.⁶ Palù, G.⁷ Loregian, A.⁸

20
- 84868028134
- G. Muratore, B. Mercorelli, L. Goracci, G. Cruciani, P. Digard, G. Palù, and A. Loregian Antimicrob. Agents Chemother. 56 2012 6009
- (2012) Antimicrob. Agents Chemother. , vol.56 , pp. 6009
- Muratore, G.¹ Mercorelli, B.² Goracci, L.³ Cruciani, G.⁴ Digard, P.⁵ Palù, G.⁶ Loregian, A.⁷

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