Beyond conventional therapy: Role of pulse steroids in bleomycin induced lung injury

Respiratory Care

Volumn 59, Issue 1, 2014, Pages

  Gupta, Raghav ^a   Ettinger, Neil A ^a  

^a ST LUKE S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; BLEOMYCIN; FIBRIN; METHYLPREDNISOLONE; PREDNISONE; STEROID;

ACUTE LUNG INJURY; AGED; ARTICLE; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; CRACKLE; DYSPNEA; FEMALE; FIBEROPTIC BRONCHOSCOPY; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; HODGKIN DISEASE; HUMAN; HYPERPLASIA; INTERSTITIAL PNEUMONIA; LOW DRUG DOSE; LUNG ALVEOLUS; LUNG FIBROSIS; LUNG FUNCTION TEST; LUNG INFILTRATE; LUNG INJURY; OXYGEN NASAL CANNULA; OXYGEN SATURATION; OXYGEN THERAPY; POINT OF CARE TESTING; THORAX RADIOGRAPHY;

ACETYLCYSTEINE; AGED; ANTI-INFLAMMATORY AGENTS; BLEOMYCIN; FEMALE; FREE RADICAL SCAVENGERS; HUMANS; LUNG INJURY; METHYLPREDNISOLONE; OXYGEN INHALATION THERAPY; RETREATMENT;

EID: 84891453361     PISSN: 00201324     EISSN: 19433654     Source Type: Journal    
DOI: 10.4187/respcare.02560     Document Type: Article

References (28)

1. Peckham MJ, Barrett A, Liew KH, Horwich A, Robinson B, Dobbs HJ, et al. The treatment of metastatic germ-cell testicular tumours with bleomycin, etoposide and cis-platin (BEP). Br J Cancer 1983; 47(5):613-619.
2. Bauer K, Skoetz N, Monsef I, Engert A, Brillant C. Comparison of chemotherapy including escalated BEACOPP versus chemotherapy including ABVD for patients with early unfavourable or advanced stage Hodgkin lymphoma. Cochrane Database Syst Rev 2011;(8): CD007941.
3. Kinjo T, Tomaru K, Haines DC, Klinman DM. The counter regulatory response induced by CpG oligonucleotides prevents bleomycin induced pneumopathy. Respir Res 2012;13:47.
4. White DA, Stover DE. Severe bleomycin-induced pneumonitis. Clinical features and response to corticosteroids. Chest 1984;86(5): 723-728.
5. Garrido M, O'Brien A, Gonzalez S, Clavero JM, Orellana E. Cryptogenic organizing pneumonitis during oxaliplatin chemotherapy for colorectal cancer: case report. Chest 2007;132(6):1997-1999.
6. Yousem SA, Lifson JD, Colby TV. Chemotherapy-induced eosinophilic pneumonia. Relation to bleomycin. Chest 1985;88(1):103-106.
7. Quigley M, Brada M, Heron C, Horwich A. Severe lung toxicity with a weekly low dose chemotherapy regimen in patients with non-Hodgkin's lymphoma. Hematol Oncol 1988;6(4):319-324.
8. Sleijfer S. Bleomycin-induced pneumonitis. Chest 2001;120(2): 617-624.
9. Filderman AE, Genovese LA, Lazo JS. Alterations in pulmonary protective enzymes following systemic bleomycin treatment in mice. Biochem Pharmacol 1988;37(6):1111-1116.
10. Tryka AF, Skornik WA, Godleski JJ, Brain JD. Potentiation of bleomycin-induced lung injury by exposure to 70% oxygen. Morphologic assessment. Am Rev Respir Dis 1982;126(6):1074-1079.
11. Tryka AF, Godleski JJ, Brain JD. Differences in effects of immediate and delayed hyperoxia exposure on bleomycin-induced pulmonary injury. Cancer Treat Rep 1984;68(5):759-764.
12. Haas CD, Coltman CA Jr, Gottlieb JA, Haut A, Luce JK, Talley RW, et al. Phase II evaluation of bleomycin. A Southwest Oncology Group study. Cancer 1976;38(1):8-12.
13. Uzel I, Ozguroglu M, Uzel B, Kaynak K, Demirhan O, Akman C, et al. Delayed onset bleomycin-induced pneumonitis. Urology 2005; 66(1):195.
14. Flieder DB, Travis WD. Pathologic characteristics of drug-induced lung disease. Clin Chest Med 2004;25(1):37-45.
15. Jensen JL, Goel R, Venner PM. The effect of corticosteroid administration on bleomycin lung toxicity. Cancer 1990;65(6):1291-1297.
16. Ng AK, Li S, Neuberg D, Chi R, Fisher DC, Silver B, et al. A prospective study of pulmonary function in Hodgkin's lymphoma patients. Ann Oncol 2008;19(10):1754-1758.
17. Shofer S, Badea C, Qi Y, Potts E, Foster WM, Johnson GA. A micro-CT analysis of murine lung recruitment in bleomycin-induced lung injury. J Appl Physiol 2008;105(2):669-677.
18. Bellamy EA, Husband JE, Blaquiere RM, Law MR. Bleomycinrelated lung damage: CT evidence. Radiology 1985;156(1):155-158.
19. Beasley MB, Franks TJ, Galvin JR, Gochuico B, Travis WD. Acute fibrinous and organizing pneumonia: a histological pattern of lung injury and possible variant of diffuse alveolar damage. Arch Pathol Lab Med 2002;126(9):1064-1070.
20. Cort A, Ozdemir E, Timur M, Ozben T. Effects of N-acetyl-Lcysteine on bleomycin induced oxidative stress in malignant testicular germ cell tumors. Biochimie 2012;94(12):2734-2739.
21. Li S, Yang X, Li W, Li J, Su X, Chen L, et al. N-acetylcysteine downregulation of lysyl oxidase activity alleviating bleomycininduced pulmonary fibrosis in rats. Respiration 2012;84(6):509-517.
22. Gilson AJ, Sahn SA. Reactivation of bleomycin lung toxicity following oxygen administration. A second response to corticosteroids. Chest 1985;88(2):304-306.
23. Seto T, Seki N, Uematsu K, Tanigaki T, Shioya S, Koboyashi T, et al. Gefitinib-induced lung injury successfully treated with highdose corticosteroids. Respirology 2006;11(1):113-116.
24. Yamamoto K, Kato T, Shindo J, Ando M, Abe T, Shiraki A, et al. [A case of irinotecan or panitumumab-induced interstitial pneumonia successfully treated by steroid pulse therapy]. Gan To Kagaku Ryoho 2012;39(2):305-309. Article in Japanese.
25. Lai YC, Lin PC, Lai JI, Hsu SY, Kuo LC, Chang SC, et al. Successful treatment of erlotinib-induced acute hepatitis and acute interstitial pneumonitis with high-dose corticosteroid: a case report and literature review. Int J Clin Pharmacol Ther 2011;49(7):461-466.
26. Maher J, Daly PA. Severe bleomycin lung toxicity: reversal with high dose corticosteroids. Thorax 1993;48(1):92-94.
27. Hartmann LC, Frytak S, Richardson RL, Coles DT, Cupps RE. Lifethreatening bleomycin pulmonary toxicity with ultimate reversibility. Chest 1990;98(2):497-499.
28. Bloor AJ, Seale JR, Marcus RE. Two cases of fatal bleomycin pneumonitis complicating the treatment of non-Hodgkin's lymphoma. Clin Lab Haematol 1998;20(2):119-121.