메뉴 건너뛰기




Volumn 52, Issue 1, 2014, Pages 46-52

Antidiabetic activity of a triterpenoid saponin isolated from Momordica cymbalaria Fenzl

Author keywords

Glucose uptake; Insulin secretion; Momordica cymbalaria

Indexed keywords

ANTIDIABETIC AGENT; CALCIUM CHANNEL; GLUCOSE; INSULIN; PLANT EXTRACT; SAPONIN; TRITERPENE;

EID: 84891424334     PISSN: 00195189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (48)

References (33)
  • 1
    • 1942424088 scopus 로고    scopus 로고
    • Natural medicines used in the traditional Chinese medical system for therapy of diabetes mellitus
    • Li W L, Zheng H C, Bukuru J & De Kimpe N, Natural medicines used in the traditional Chinese medical system for therapy of diabetes mellitus, J Ethnopharmacol, 92 (2004) 1.
    • (2004) J Ethnopharmacol , vol.92 , pp. 1
    • Li, W.L.1    Zheng, H.C.2    Bukuru, J.3    De Kimpe, N.4
  • 3
    • 0037291184 scopus 로고    scopus 로고
    • Evaluation of antidiabetic effect of Momordica cymbalaria fruit in alloxan-diabetic rats
    • Kameswararao B, Kesavulu M M & Apparao C, Evaluation of antidiabetic effect of Momordica cymbalaria fruit in alloxan-diabetic rats, Fitoterpia, 74 (2003) 7.
    • (2003) Fitoterpia , vol.74 , pp. 7
    • Kameswararao, B.1    Kesavulu, M.M.2    Apparao, C.3
  • 4
    • 0034802090 scopus 로고    scopus 로고
    • Antihyperglycemic activity of Momordica cymbalaria in alloxan diabetic rats
    • Kameswararao B, Kesavulu M M & Apparao C, Antihyperglycemic activity of Momordica cymbalaria in alloxan diabetic rats, J Ethnopharmacol, 78 (2001) 67.
    • (2001) J Ethnopharmacol , vol.78 , pp. 67
    • Kameswararao, B.1    Kesavulu, M.M.2    Apparao, C.3
  • 5
    • 0032785269 scopus 로고    scopus 로고
    • Antidiabetic and hypolipidemic effect of Momordica cymbalaria Hook fruit powder in alloxan-diabetic rats
    • Kameswararao B, Kesavulu M M, Giri R & Apparao C, Antidiabetic and hypolipidemic effect of Momordica cymbalaria Hook fruit powder in alloxan-diabetic rats, J Ethnopharmacol 67 (1999) 103.
    • (1999) J Ethnopharmacol , vol.67 , pp. 103
    • Kameswararao, B.1    Kesavulu, M.M.2    Giri, R.3    Apparao, C.4
  • 6
    • 69749085983 scopus 로고    scopus 로고
    • Antidiabetic mechanisms of saponins of Momordica cymbalaria
    • Raju K & Balaraman R, Antidiabetic mechanisms of saponins of Momordica cymbalaria, Phcog Mag, 4 (2008) 160.
    • (2008) Phcog Mag , vol.4 , pp. 160
    • Raju, K.1    Balaraman, R.2
  • 7
    • 33744503928 scopus 로고    scopus 로고
    • Antiovulatory and abortifacient potential of the ethanolic extract of roots of Momordica cymbalaria Fenzl in rats
    • Koneri R, Balaraman R & Saraswati C D, Antiovulatory and abortifacient potential of the ethanolic extract of roots of Momordica cymbalaria Fenzl in rats, Indian J Pharmacol, 38 (2006) 111.
    • (2006) Indian J Pharmacol , vol.38 , pp. 111
    • Koneri, R.1    Balaraman, R.2    Saraswati, C.D.3
  • 8
    • 34250187435 scopus 로고    scopus 로고
    • Antiimplantation activity of the ethanolic root extract of Momordica cymbalaria Fenzl in rats
    • Koneri R, Saraswati C D, Balaraman R & Ajeesha E A, Antiimplantation activity of the ethanolic root extract of Momordica cymbalaria Fenzl in rats, Indian J Pharmacol, 9 (2007) 90.
    • (2007) Indian J Pharmacol , vol.9 , pp. 90
    • Koneri, R.1    Saraswati, C.D.2    Balaraman, R.3    Ajeesha, E.A.4
  • 9
    • 44249123440 scopus 로고    scopus 로고
    • Cardioprotective effect of Momordica cymbalaria Fenzl in rats with isoproterenol-induced myocardial injury
    • Koneri R, Balaraman R, Hariprasad, Vinoth Kumar M & Ali A, Cardioprotective effect of Momordica cymbalaria Fenzl in rats with isoproterenol-induced myocardial injury, J Clin Diagnos Res, 2 (2008) 699.
    • (2008) J Clin Diagnos Res , vol.2 , pp. 699
    • Koneri, R.1    Balaraman, R.2    Hariprasad, V.K.M.3    Ali, A.4
  • 10
    • 38649117587 scopus 로고    scopus 로고
    • Antimicrobial properties of Momordica cymbalaria Hook
    • Swamy V B M & Jayaveera K N, Antimicrobial properties of Momordica cymbalaria Hook, Pharmacologyonline, 3 (2007) 505.
    • (2007) Pharmacologyonline , vol.3 , pp. 505
    • Swamy, V.B.M.1    Jayaveera, K.N.2
  • 11
    • 78951470142 scopus 로고    scopus 로고
    • Isolation and characterization of phytoconstituents from Chlorophytum borivilianum
    • Sharada L D & Somshekhar S K, Isolation and characterization of phytoconstituents from Chlorophytum borivilianum, Pharmacognosy Res, 2 (2010) 343.
    • (2010) Pharmacognosy Res , vol.2 , pp. 343
    • Sharada, L.D.1    Somshekhar, S.K.2
  • 12
    • 84984550400 scopus 로고    scopus 로고
    • Aqueous extracts of Sphagneticola trilobata attenuates streptozotocin-induced hyperglycemia in rat models by modulating oxidative stress parameters
    • Kade I & Barbosa N, Aqueous extracts of Sphagneticola trilobata attenuates streptozotocin-induced hyperglycemia in rat models by modulating oxidative stress parameters, Biol Med, 2 (2010) 1.
    • (2010) Biol Med , vol.2 , pp. 1
    • Kade, I.1    Barbosa, N.2
  • 13
    • 11844281527 scopus 로고    scopus 로고
    • The antidiabetic activity of the herbal preparation ADD-199 in mice: A comparative study with two oral hypoglycaemic drugs
    • Okine L & Nyarkb N. The antidiabetic activity of the herbal preparation ADD-199 in mice: a comparative study with two oral hypoglycaemic drugs. J Ethanopharmacol, 97 (2005) 37.
    • (2005) J Ethanopharmacol , vol.97 , pp. 37
    • Okine, L.1    Nyarkb, N.2
  • 15
    • 0032145419 scopus 로고    scopus 로고
    • Stephen J & Ashcrot, Pharmacological chracterisation of the antihyperglycemic properties of Tinospora crispa extract
    • Hamdan N, Stephen J & Ashcrot, Pharmacological chracterisation of the antihyperglycemic properties of Tinospora crispa extract, J Ethanopharmacol, 62 (1998) 7.
    • (1998) J Ethanopharmacol , vol.62 , pp. 7
    • Hamdan, N.1
  • 16
    • 67650270881 scopus 로고    scopus 로고
    • Hypoglycemic herbs and their action mechanisms
    • Hongxiang H, George T, & Liang V W G, Hypoglycemic herbs and their action mechanisms, Chin Med, 4 (2009) 11.
    • (2009) Chin Med , vol.4 , pp. 11
    • Hongxiang, H.1    George, T.2    Liang, V.W.G.3
  • 17
    • 78249285581 scopus 로고    scopus 로고
    • Anti-hyperglycemic compound (GII) from fenugreek (Trigonella foenumgraecum Linn.) seeds, its purification and effect in diabetes mellitus
    • Moorthy R, Prabhu K M & Murthy P S, Anti-hyperglycemic compound (GII) from fenugreek (Trigonella foenumgraecum Linn.) seeds, its purification and effect in diabetes mellitus, Indian J Exp Biol, 48 (2010) 1111.
    • (2010) Indian J Exp Biol , vol.48 , pp. 1111
    • Moorthy, R.1    Prabhu, K.M.2    Murthy, P.S.3
  • 18
    • 83655182493 scopus 로고    scopus 로고
    • Mechanism of antidiabetic action of compound GII purified from Fenugreek (Trigonella foenum graecum) seeds
    • Puri D, Prabhu K M, Dev G, Agarwal S & Murthy P S, Mechanism of antidiabetic action of compound GII purified from Fenugreek (Trigonella foenum graecum) seeds, Indian J Clin Biochem, 26 (2011) 335.
    • (2011) Indian J Clin Biochem , vol.26 , pp. 335
    • Puri, D.1    Prabhu, K.M.2    Dev, G.3    Agarwal, S.4    Murthy, P.S.5
  • 20
    • 0030436918 scopus 로고    scopus 로고
    • Purification of three orally active hypoglycemic compounds Kakara Ib, IIIa1 and IIIb1 from the unripe fruits of Momordica charantia Linn (Bitter gourd)
    • Pugazhenthi S & Murthy P S, Purification of three orally active hypoglycemic compounds Kakara Ib, IIIa1 and IIIb1 from the unripe fruits of Momordica charantia Linn (Bitter gourd), Indian J Clin Biochem, 11 (1996), 115.
    • (1996) Indian J Clin Biochem , vol.11 , pp. 115
    • Pugazhenthi, S.1    Murthy, P.S.2
  • 21
    • 0043152700 scopus 로고    scopus 로고
    • Insulin, oral hypoglycemic agents and the pharmacology of the endocrine pancreas
    • 10th ed. (McGraw-Hill Medical Publishing Division)
    • Gilman A G, Hardman J G, & Limbard L E, Insulin, oral hypoglycemic agents and the pharmacology of the endocrine pancreas. The pharmacological basis of therapeutics 10th ed. (McGraw-Hill Medical Publishing Division) 2001, 1679.
    • (2001) The pharmacological basis of therapeutics , pp. 1679
    • Gilman, A.G.1    Hardman, J.G.2    Limbard, L.E.3
  • 22
    • 0026715787 scopus 로고
    • Effect of extract of leaves of Vinca rosea Linn on glucose utilization and glycogen deposition by isolated rat hemidiaphragm
    • Chattopadhyay R R, Sarkar S K, Ganguly S, Banerjee R N, & Basu T K, Effect of extract of leaves of Vinca rosea Linn on glucose utilization and glycogen deposition by isolated rat hemidiaphragm, Indian J Physiol Pharmacol, 36 (1992) 137.
    • (1992) Indian J Physiol Pharmacol , vol.36 , pp. 137
    • Chattopadhyay, R.R.1    Sarkar, S.K.2    Ganguly, S.3    Banerjee, R.N.4    Basu, T.K.5
  • 24
    • 55149111149 scopus 로고    scopus 로고
    • Korean red ginseng stimulates insulin release from isolated rat pancreatic islets
    • Kim K & Kim H Y, Korean red ginseng stimulates insulin release from isolated rat pancreatic islets, J Ethnopharmacol, 120 (2008) 190.
    • (2008) J Ethnopharmacol , vol.120 , pp. 190
    • Kim, K.1    Kim, H.Y.2
  • 25
    • 26244435115 scopus 로고    scopus 로고
    • Effect of bitter gourd (Momordica charantia) on glycaemic status in streptozotocin induced diabetic rats
    • Shetty A K, Kumar G S, Sambaiah K & Salimath P V, Effect of bitter gourd (Momordica charantia) on glycaemic status in streptozotocin induced diabetic rats, Plant Foods Hum Nutr, 60 (2005) 109.
    • (2005) Plant Foods Hum Nutr , vol.60 , pp. 109
    • Shetty, A.K.1    Kumar, G.S.2    Sambaiah, K.3    Salimath, P.V.4
  • 26
    • 0347418244 scopus 로고    scopus 로고
    • Bitter gourd (Momordica charantia) extract activates peroxisome proliferator-activated receptors and upregulates the expression of the acyl coA oxidase gene in H4IIEC3 hepatoma cells
    • Chao C Y & Huang C, Bitter gourd (Momordica charantia) extract activates peroxisome proliferator-activated receptors and upregulates the expression of the acyl coA oxidase gene in H4IIEC3 hepatoma cells, J Biomed Sci, 10 (2003) 782.
    • (2003) J Biomed Sci , vol.10 , pp. 782
    • Chao, C.Y.1    Huang, C.2
  • 27
    • 0030855907 scopus 로고    scopus 로고
    • Activation of alpha-2 adrenergic receptors inhibits norepinephrine release by a pertussis toxininsensitive pathway independent of changes in cytosolic calcium in cultured rat sympathetic neurons
    • Schwartz D D, Activation of alpha-2 adrenergic receptors inhibits norepinephrine release by a pertussis toxininsensitive pathway independent of changes in cytosolic calcium in cultured rat sympathetic neurons, J Pharmacol Exper Therp, 282 (1997) 248.
    • (1997) J Pharmacol Exper Therp , vol.282 , pp. 248
    • Schwartz, D.D.1
  • 29
    • 0025125889 scopus 로고
    • Mechanism of sympathetic neural regulation of insulin, somatostatin, and glucagon secretion
    • Kurose T, Seino Y, Nishi S, Tsuji K, Taminato T, Tsuda K & Imura H, Mechanism of sympathetic neural regulation of insulin, somatostatin, and glucagon secretion, Am J Physiol, 258 (1990) 220.
    • (1990) Am J Physiol , vol.258 , pp. 220
    • Kurose, T.1    Seino, Y.2    Nishi, S.3    Tsuji, K.4    Taminato, T.5    Tsuda, K.6    Imura, H.7
  • 30
    • 0023845918 scopus 로고
    • Yohimbine increases plasma insulin concentrations and reverses xylazine-induced hypoinsulinemia in dogs
    • Hsu W H, Yohimbine increases plasma insulin concentrations and reverses xylazine-induced hypoinsulinemia in dogs, Am J Vet Res, 49 (1988) 242.
    • (1988) Am J Vet Res , vol.49 , pp. 242
    • Hsu, W.H.1
  • 31
    • 34347239704 scopus 로고    scopus 로고
    • Effects of yohimbine on plasma levels of leptin in normal and streptozotocin induced diabetic rats
    • Naghadeh M M, Moghadam F H & Ibrahimi H, Effects of yohimbine on plasma levels of leptin in normal and streptozotocin induced diabetic rats, Acta Medica Iranica, 44 (2006) 77.
    • (2006) Acta Medica Iranica , vol.44 , pp. 77
    • Naghadeh, M.M.1    Moghadam, F.H.2    Ibrahimi, H.3
  • 32
    • 33947394924 scopus 로고    scopus 로고
    • Insulin secretory actions of extracts of Asparagus racemosus root in perfused pancreas, isolated islets and clonal pancreatic beta cells
    • Hannan J M, Marenah L, Ali L, Rokeya B, Flatt P R & Abdel-Wahab Y H, Insulin secretory actions of extracts of Asparagus racemosus root in perfused pancreas, isolated islets and clonal pancreatic beta cells, J Endocrinol, 192 (2007) 159.
    • (2007) J Endocrinol , vol.192 , pp. 159
    • Hannan, J.M.1    Marenah, L.2    Ali, L.3    Rokeya, B.4    Flatt, P.R.5    Abdel-Wahab, Y.H.6
  • 33
    • 33646354159 scopus 로고    scopus 로고
    • Ocimum sanctum leaf extracts stimulate insulin secretion from perfused pancreas, isolated islets and clonal pancreatic beta-cells
    • Hannan J M, Marenah L, Ali L, Rokeya B, Flatt P R & Abdel-Wahab Y H, Ocimum sanctum leaf extracts stimulate insulin secretion from perfused pancreas, isolated islets and clonal pancreatic beta-cells, J Endocrinol, 189 (2006) 127.
    • (2006) J Endocrinol , vol.189 , pp. 127
    • Hannan, J.M.1    Marenah, L.2    Ali, L.3    Rokeya, B.4    Flatt, P.R.5    Abdel-Wahab, Y.H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.