Concerted in vitro trimming of viral HLA-B27-restricted ligands by human ERAP1 and ERAP2 aminopeptidases

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Lorente, Elena ^a   Barriga, Alejandro ^a   Johnstone, Carolina ^a   Mir, Carmen ^a   Jiménez, Mercedes ^a   López, Daniel ^a  

^a INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ALANYLMETHIONYLALANYLARGINYLLEUCYLARGINYLASPARAGINYLGLUTAMYLGLUTAMYLSERYLGLUTAMYLLYSYLMETHIONYLALANYLLYSINE; AMINOPEPTIDASE; ERAP1 AMINOPEPTIDASE; ERAP2 AMINOPEPTIDASE; HLA B27 ANTIGEN; LYSYLASPARAGINYLGLUTAMYLMETHIONYLLYSYLARGINYLTYROSYLLYSYLGLYCYLLEUCYLLEUCYLPROLYLLYSYLASPARTYLISOLEUCINE; PEPTIDE DERIVATIVE; PROTEINASE; RECOMBINANT ENZYME; THREONYLARGINYLASPARTYLISOLEUCYLISOLEUCYLTHREONYLHISTIDYLARGINYLPHENYLALANYLISOLEUCYLTYROSYLLEUCYLISOLEUCYLASPARAGINYLHISTIDINE; TYROSYLLEUCYLARGINYLSERYLISOLEUCYLSERYLVALYLARGINYLASPARAGINYLLYSYLASPARTYLLEUCYLASPARAGINYLTHREONYLLEUCINE; UNCLASSIFIED DRUG; VALYLASPARTYLVALYLTHREONYLTHREONYLHISTIDYLARGINYLGLUTAMINYLASPARTYLISOLEUCYLASPARAGINYLGLYCYLLYSYLGLUTAMYLMETHIONINE;

AMINO TERMINAL SEQUENCE; ANTIGEN PRESENTATION; ARTICLE; CONCENTRATION (PARAMETERS); ENDOPLASMIC RETICULUM; ENZYMATIC DEGRADATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME METABOLISM; ENZYME SUBSTRATE; ENZYME SYNTHESIS; IN VITRO STUDY; LIGAND BINDING; MASS SPECTROMETRY; NONHUMAN; PROTEIN DEGRADATION;

AMINO ACID SEQUENCE; AMINOPEPTIDASES; HLA-B27 ANTIGEN; HUMANS; LIGANDS; MOLECULAR SEQUENCE DATA; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEOLYSIS; RESPIRATORY SYNCYTIAL VIRUS, HUMAN; VIRAL PROTEINS;

EID: 84891416651     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0079596     Document Type: Article

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