메뉴 건너뛰기




Volumn 15, Issue 6, 2013, Pages

Genetics of HDL-C: A causal link to atherosclerosis? Topical collection on genetics

Author keywords

Apolipoprotein A I; Atherosclerosis; ATP binding cassette transporter A1; Cardiovascular disease; Cholesteryl ester transport protein; Endothelial lipase; Genetics; Genome wide association; HDL cholesterol; Lecithin cholesterol acyltransferase; Mendelian randomization; Phospholipid transfer protein; Scavenger receptor class B type 1

Indexed keywords

ABC TRANSPORTER A1; ABC TRANSPORTER G1; ANACETRAPIB; APOLIPOPROTEIN A1; CHOLESTEROL ESTER TRANSFER PROTEIN; CHOLESTEROL ESTER TRANSFER PROTEIN INHIBITOR; DALCETRAPIB; ENDOTHELIAL LIPASE; EVACETRAPIB; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PHOSPHATIDYLCHOLINE STEROL ACYLTRANSFERASE; PHOSPHOLIPID TRANSFER PROTEIN; SCAVENGER RECEPTOR BI; TA 8995; TORCETRAPIB; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

EID: 84891414969     PISSN: 15233804     EISSN: 15346242     Source Type: Journal    
DOI: 10.1007/s11883-013-0326-8     Document Type: Article
Times cited : (33)

References (93)
  • 1
    • 36549034768 scopus 로고    scopus 로고
    • Blood cholesterol and vascular mortality by age, sex, and blood pressure: A meta-analysis of individual data from 61 prospective studies with 55 000 vascular deaths
    • DOI 10.1016/S0140-6736(07)61778-4, PII S0140673607617784
    • Lewington S, Whitlock G, Clarke R, et al. Blood cholesterol and vascular mortality by age, sex, and blood pressure: a meta-analysis of individual data from 61 prospective studies with 55,000 vascular deaths. Lancet. 2007;370(9602):1829-39. (Pubitemid 350180032)
    • (2007) Lancet , vol.370 , Issue.9602 , pp. 1829-1839
  • 2
    • 70450081001 scopus 로고    scopus 로고
    • Major lipids, apolipoproteins, and risk of vascular disease
    • 19903920 10.1001/jama.2009.1619
    • Di Angelantonio E, Sarwar N, Perry P, et al. Major lipids, apolipoproteins, and risk of vascular disease. JAMA. 2009;302(18):1993-2000.
    • (2009) JAMA , vol.302 , Issue.18 , pp. 1993-2000
    • Di Angelantonio, E.1    Sarwar, N.2    Perry, P.3
  • 4
    • 0027987849 scopus 로고
    • Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study (4S)
    • Scandinavian Simvastatin Survival Study Group
    • Scandinavian Simvastatin Survival Study Group. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet. 1994;344(8934):1383-9.
    • (1994) Lancet , vol.344 , Issue.8934 , pp. 1383-1389
  • 6
    • 84870048419 scopus 로고    scopus 로고
    • High-density lipoprotein function, dysfunction, and reverse cholesterol transport
    • 23152494 10.1161/ATVBAHA.112.300133 1:CAS:528:DC%2BC38Xhs1GqsbzI Excellent recent review on HDL functionality
    • Fisher EA, Feig JE, Hewing B, et al. High-density lipoprotein function, dysfunction, and reverse cholesterol transport. Arterioscler Thromb Vasc Biol. 2012;32(12):2813-20. Excellent recent review on HDL functionality.
    • (2012) Arterioscler Thromb Vasc Biol , vol.32 , Issue.12 , pp. 2813-2820
    • Fisher, E.A.1    Feig, J.E.2    Hewing, B.3
  • 7
    • 79953192995 scopus 로고    scopus 로고
    • HDL and cardiovascular disease: Atherogenic and atheroprotective mechanisms
    • 21304474 10.1038/nrcardio.2010.222 1:CAS:528:DC%2BC3MXjvVKns7s%3D
    • Navab M, Reddy ST, Van Lenten BJ, Fogelman AM. HDL and cardiovascular disease: atherogenic and atheroprotective mechanisms. Nat Rev Cardiol. 2011;8(4):222-32.
    • (2011) Nat Rev Cardiol , vol.8 , Issue.4 , pp. 222-232
    • Navab, M.1    Reddy, S.T.2    Van Lenten, B.J.3    Fogelman, A.M.4
  • 8
    • 84863985473 scopus 로고    scopus 로고
    • HDL functionality
    • 22732521 10.1097/MOL.0b013e328355ca25 1:CAS:528:DC%2BC38XhtVegtL7I
    • Soran H, Hama S, Yadav R, Durrington PN. HDL functionality. Curr Opin Lipidol. 2012;23(4):353-66.
    • (2012) Curr Opin Lipidol , vol.23 , Issue.4 , pp. 353-366
    • Soran, H.1    Hama, S.2    Yadav, R.3    Durrington, P.N.4
  • 9
    • 84855171302 scopus 로고    scopus 로고
    • Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy
    • 22085343 10.1056/NEJMoa1107579
    • Boden WE, Probstfield JL, Anderson T, et al. Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy. N Engl J Med. 2011;365(24):2255-67.
    • (2011) N Engl J Med , vol.365 , Issue.24 , pp. 2255-2267
    • Boden, W.E.1    Probstfield, J.L.2    Anderson, T.3
  • 10
    • 84870045994 scopus 로고    scopus 로고
    • Effects of dalcetrapib in patients with a recent acute coronary syndrome
    • 23126252 10.1056/NEJMoa1206797 1:CAS:528:DC%2BC38XhslyltrvK
    • Schwartz GG, Olsson AG, Abt M, et al. Effects of dalcetrapib in patients with a recent acute coronary syndrome. N Engl J Med. 2012;367(22):2089-99.
    • (2012) N Engl J Med , vol.367 , Issue.22 , pp. 2089-2099
    • Schwartz, G.G.1    Olsson, A.G.2    Abt, M.3
  • 13
    • 31744449136 scopus 로고    scopus 로고
    • The sex-specific genetic architecture of quantitative traits in humans
    • DOI 10.1038/ng1726, PII NG1726
    • Weiss LA, Pan L, Abney M, Ober C. The sex-specific genetic architecture of quantitative traits in humans. Nat Genet. 2006;38(2):218-22. (Pubitemid 43177237)
    • (2006) Nature Genetics , vol.38 , Issue.2 , pp. 218-222
    • Weiss, L.A.1    Pan, L.2    Abney, M.3    Ober, C.4
  • 14
    • 77955505564 scopus 로고    scopus 로고
    • Biological, clinical and population relevance of 95 loci for blood lipids
    • 20686565 10.1038/nature09270 1:CAS:528:DC%2BC3cXhtVSmurfI
    • Teslovich TM, Musunuru K, Smith AV, et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature. 2010;466(7307):707-13.
    • (2010) Nature , vol.466 , Issue.7307 , pp. 707-713
    • Teslovich, T.M.1    Musunuru, K.2    Smith, A.V.3
  • 15
    • 84868470681 scopus 로고    scopus 로고
    • Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci
    • One of the most recent large scale gene centric meta-analysis on lipid heritablity
    • Asselbergs FW, Guo Y, Van Iperen EPA, et al. Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. Am J Hum Genet. 2012;91(5):823-838. One of the most recent large scale gene centric meta-analysis on lipid heritablity.
    • (2012) Am J Hum Genet. , vol.91 , Issue.5 , pp. 823-838
    • Asselbergs, F.W.1    Guo, Y.2    Van Iperen Epa3
  • 16
    • 69549103151 scopus 로고    scopus 로고
    • Functional lecithin: Cholesterol acyltransferase is not required for efficient atheroprotection in humans
    • 19687369 1:CAS:528:DC%2BD1MXpsFylu74%3D
    • Calabresi L, Baldassarre D, Castelnuovo S, et al. Functional lecithin: cholesterol acyltransferase is not required for efficient atheroprotection in humans. Circulation. 2009;120(7):628-35.
    • (2009) Circulation , vol.120 , Issue.7 , pp. 628-635
    • Calabresi, L.1    Baldassarre, D.2    Castelnuovo, S.3
  • 19
    • 84879567781 scopus 로고    scopus 로고
    • ABCA1 mutation carriers with low high-density lipoprotein cholesterol are characterized by a larger atherosclerotic burden
    • doi: 10.1093/eurheartj/ehs376
    • Bochem AE, Van Wijk DF, Holleboom AG, et al. ABCA1 mutation carriers with low high-density lipoprotein cholesterol are characterized by a larger atherosclerotic burden. Eur Heart J. 2012. doi: 10.1093/eurheartj/ehs376.
    • (2012) Eur Heart J.
    • Bochem, A.E.1    Van Wijk, D.F.2    Holleboom, A.G.3
  • 20
    • 84864845456 scopus 로고    scopus 로고
    • Plasma HDL cholesterol and risk of myocardial infarction: A mendelian randomisation study
    • 22607825 10.1016/S0140-6736(12)60312-2 1:CAS:528:DC%2BC38Xnt1Cmsrc%3D Recent Mendelian randomization study that found no association between EL gene variation, HDL-C values and CVD risk
    • •• Voight BF, Peloso GM, Orho-Melander M, et al. Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet. 2012;380(9841):572-80. Recent Mendelian randomization study that found no association between EL gene variation, HDL-C values and CVD risk.
    • (2012) Lancet , vol.380 , Issue.9841 , pp. 572-580
    • Voight, B.F.1    Peloso, G.M.2    Orho-Melander, M.3
  • 21
    • 84856786437 scopus 로고    scopus 로고
    • LCAT, HDL cholesterol and ischemic cardiovascular disease: A mendelian randomization study of HDL cholesterol in 54,500 individuals
    • 22090275 10.1210/jc.2011-1846 1:CAS:528:DC%2BC38XisFOns70%3D
    • Haase CL, Tybjærg-Hansen A, Qayyum AA, et al. LCAT, HDL cholesterol and ischemic cardiovascular disease: a mendelian randomization study of HDL cholesterol in 54,500 individuals. J Clin Endocrinol Metab. 2012;97(2):E248-56.
    • (2012) J Clin Endocrinol Metab , vol.97 , Issue.2
    • Haase, C.L.1    Tybjærg-Hansen, A.2    Qayyum, A.A.3
  • 22
    • 0242467726 scopus 로고    scopus 로고
    • APOA1 related amyloidosis: A case report and literature review
    • DOI 10.1016/S0009-9120(03)00110-3
    • Joy T, Wang J, Hahn A, Hegele RA. APOA1 related amyloidosis: a case report and literature review. Clin Biochem. 2003;36(8):641-5. (Pubitemid 37434032)
    • (2003) Clinical Biochemistry , vol.36 , Issue.8 , pp. 641-645
    • Joy, T.1    Wang, J.2    Hahn, A.3    Hegele, R.A.4
  • 23
    • 79960460644 scopus 로고    scopus 로고
    • Human apolipoprotein A-I-derived amyloid: Its association with atherosclerosis
    • 21811627 10.1371/journal.pone.0022532 1:CAS:528:DC%2BC3MXhtVehtLnO
    • Ramella NA, Rimoldi OJ, Prieto ED, et al. Human apolipoprotein A-I-derived amyloid: its association with atherosclerosis. PLoS One. 2011;6(7):e22532.
    • (2011) PLoS One , vol.6 , Issue.7 , pp. 22532
    • Ramella, N.A.1    Rimoldi, O.J.2    Prieto, E.D.3
  • 25
    • 70350575335 scopus 로고    scopus 로고
    • Marked high density lipoprotein deficiency due to apolipoprotein A-I Tomioka (codon 138 deletion)
    • 19473658 10.1016/j.atherosclerosis.2009.04.018 1:CAS:528: DC%2BD1MXhtlyrtbbJ
    • Wada M, Iso T, Asztalos BF, et al. Marked high density lipoprotein deficiency due to apolipoprotein A-I Tomioka (codon 138 deletion). Atherosclerosis. 2009;207(1):157-61.
    • (2009) Atherosclerosis , vol.207 , Issue.1 , pp. 157-161
    • Wada, M.1    Iso, T.2    Asztalos, B.F.3
  • 26
    • 77957878033 scopus 로고    scopus 로고
    • Complete Apo AI deficiency in an Iraqi Mandaean family: Case studies and review of the literature
    • Al-Sarraf A, Al-Ghofaili K, Sullivan DR, et al. Complete Apo AI deficiency in an Iraqi Mandaean family: case studies and review of the literature. J Clin Lipidol. 2010;4(5):420-6.
    • (2010) J Clin Lipidol. , vol.4 , Issue.5 , pp. 420-426
    • Al-Sarraf, A.1    Al-Ghofaili, K.2    Sullivan, D.R.3
  • 28
    • 84857628622 scopus 로고    scopus 로고
    • Increased risk of coronary artery disease in Caucasians with extremely low HDL cholesterol due to mutations in ABCA1, APOA1, and LCAT
    • 21875686 10.1016/j.bbalip.2011.08.006 1:CAS:528:DC%2BC38XjtFWgtbs%3D
    • Tietjen I, Hovingh GK, Singaraja R, et al. Increased risk of coronary artery disease in Caucasians with extremely low HDL cholesterol due to mutations in ABCA1, APOA1, and LCAT. Biochim Biophys Acta. 2012;1821(3):416-24.
    • (2012) Biochim Biophys Acta , vol.1821 , Issue.3 , pp. 416-424
    • Tietjen, I.1    Hovingh, G.K.2    Singaraja, R.3
  • 29
    • 84870705395 scopus 로고    scopus 로고
    • Population-based resequencing of APOA1 in 10,330 individuals: Spectrum of genetic variation, phenotype, and comparison with extreme phenotype approach
    • 23209431 10.1371/journal.pgen.1003063 1:CAS:528:DC%2BC38XhvVKjtrfF
    • Haase CL, Frikke-Schmidt R, Nordestgaard BG, Tybjærg-Hansen A. Population-based resequencing of APOA1 in 10,330 individuals: spectrum of genetic variation, phenotype, and comparison with extreme phenotype approach. PLoS Genet. 2012;8(11):e1003063.
    • (2012) PLoS Genet. , vol.8 , Issue.11 , pp. 1003063
    • Haase, C.L.1    Frikke-Schmidt, R.2    Nordestgaard, B.G.3    Tybjærg-Hansen, A.4
  • 30
    • 79960241608 scopus 로고    scopus 로고
    • Mutation in APOA1 predicts increased risk of ischaemic heart disease and total mortality without low HDL cholesterol levels
    • 21443680 10.1111/j.1365-2796.2011.02381.x 1:CAS:528:DC%2BC3MXhtV2qt77M
    • Haase CL, Frikke-Schmidt R, Nordestgaard BG, et al. Mutation in APOA1 predicts increased risk of ischaemic heart disease and total mortality without low HDL cholesterol levels. J Intern Med. 2011;270(2):136-46.
    • (2011) J Intern Med , vol.270 , Issue.2 , pp. 136-146
    • Haase, C.L.1    Frikke-Schmidt, R.2    Nordestgaard, B.G.3
  • 31
    • 71749083863 scopus 로고    scopus 로고
    • The genetics of high-density lipoprotein metabolism: Clinical relevance for therapeutic approaches
    • 19895941 10.1016/j.amjcard.2009.09.016 1:CAS:528:DC%2BD1MXhs1Wju7rP
    • Strang AC, Hovingh GK, Stroes ESG, Kastelein JJP. The genetics of high-density lipoprotein metabolism: clinical relevance for therapeutic approaches. Am J Cardiol. 2009;104(10 Suppl):22E-31E.
    • (2009) Am J Cardiol , vol.104 , Issue.10 SUPPL.
    • Strang, A.C.1    Hovingh, G.K.2    Stroes, E.S.G.3    Kastelein, J.J.P.4
  • 35
    • 84155166795 scopus 로고    scopus 로고
    • Recombinant HDL(Milano) exerts greater anti-inflammatory and plaque stabilizing properties than HDL(wild-type)
    • 22030095 10.1016/j.atherosclerosis.2011.10.006 1:CAS:528: DC%2BC3MXhs12htLvM
    • Ibanez B, Giannarelli C, Cimmino G, et al. Recombinant HDL(Milano) exerts greater anti-inflammatory and plaque stabilizing properties than HDL(wild-type). Atherosclerosis. 2012;220(1):72-7.
    • (2012) Atherosclerosis , vol.220 , Issue.1 , pp. 72-77
    • Ibanez, B.1    Giannarelli, C.2    Cimmino, G.3
  • 36
    • 70349579203 scopus 로고    scopus 로고
    • Macrophage reverse cholesterol transport in mice expressing ApoA-I Milano
    • 19661486 10.1161/ATVBAHA.109.191379 1:CAS:528:DC%2BD1MXhtFWhur%2FM
    • Alexander ET, Weibel GL, Joshi MR, et al. Macrophage reverse cholesterol transport in mice expressing ApoA-I Milano. Arterioscler Thromb Vasc Biol. 2009;29(10):1496-501.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , Issue.10 , pp. 1496-1501
    • Alexander, E.T.1    Weibel, G.L.2    Joshi, M.R.3
  • 37
    • 79951853624 scopus 로고    scopus 로고
    • Apolipoprotein mimetic peptides: Mechanisms of action as anti-atherogenic agents
    • 21172387 10.1016/j.pharmthera.2010.12.003 1:CAS:528:DC%2BC3MXit1Gmtrc%3D
    • Osei-Hwedieh DO, Amar M, Sviridov D, Remaley AT. Apolipoprotein mimetic peptides: Mechanisms of action as anti-atherogenic agents. Pharmacol Ther. 2011;130(1):83-91.
    • (2011) Pharmacol Ther , vol.130 , Issue.1 , pp. 83-91
    • Osei-Hwedieh, D.O.1    Amar, M.2    Sviridov, D.3    Remaley, A.T.4
  • 41
    • 74749083466 scopus 로고    scopus 로고
    • Genetic variation in the ABCA1 gene, HDL cholesterol, and risk of ischemic heart disease in the general population
    • 19596329 10.1016/j.atherosclerosis.2009.06.005 1:CAS:528: DC%2BC3cXhtlyru78%3D
    • Frikke-Schmidt R. Genetic variation in the ABCA1 gene, HDL cholesterol, and risk of ischemic heart disease in the general population. Atherosclerosis. 2010;208(2):305-16.
    • (2010) Atherosclerosis , vol.208 , Issue.2 , pp. 305-316
    • Frikke-Schmidt, R.1
  • 42
    • 78649757011 scopus 로고    scopus 로고
    • Identification and characterization of novel loss of function mutations in ATP-binding cassette transporter A1 in patients with low plasma high-density lipoprotein cholesterol
    • 20880529 10.1016/j.atherosclerosis.2010.08.062 1:CAS:528: DC%2BC3cXhsFams7jL
    • Candini C, Schimmel AW, Peter J, et al. Identification and characterization of novel loss of function mutations in ATP-binding cassette transporter A1 in patients with low plasma high-density lipoprotein cholesterol. Atherosclerosis. 2010;213(2):492-8.
    • (2010) Atherosclerosis , vol.213 , Issue.2 , pp. 492-498
    • Candini, C.1    Schimmel, A.W.2    Peter, J.3
  • 43
  • 44
    • 37549059892 scopus 로고    scopus 로고
    • Genetic variation in ABCA1 predicts ischemic heart disease in the general population
    • 17951323 10.1161/ATVBAHA.107.153858 1:CAS:528:DC%2BD2sXhsVeiu7bN
    • Frikke-Schmidt R, Nordestgaard BG, Jensen GB, et al. Genetic variation in ABCA1 predicts ischemic heart disease in the general population. Arterioscler Thromb Vasc Biol. 2008;28(1):180-6.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , Issue.1 , pp. 180-186
    • Frikke-Schmidt, R.1    Nordestgaard, B.G.2    Jensen, G.B.3
  • 47
    • 35248832546 scopus 로고    scopus 로고
    • Common genetic variation in the ATP-binding cassette transporter A1, plasma lipids, and risk of coronary heart disease
    • DOI 10.1016/j.atherosclerosis.2007.01.025, PII S0021915007000597
    • Jensen MK, Pai JK, Mukamal KJ, et al. Common genetic variation in the ATP-binding cassette transporter A1, plasma lipids, and risk of coronary heart disease. Atherosclerosis. 2007;195(1):e172-80. (Pubitemid 47561955)
    • (2007) Atherosclerosis , vol.195 , Issue.1
    • Jensen, M.K.1    Pai, J.K.2    Mukamal, K.J.3    Overvad, K.4    Rimm, E.B.5
  • 48
    • 84869068064 scopus 로고    scopus 로고
    • The ABCA1 Gene R230C variant is associated with decreased risk of premature coronary artery disease: The Genetics of Atherosclerotic Disease (GEA) Study
    • 23152888 10.1371/journal.pone.0049285 1:CAS:528:DC%2BC38XhslKjsbfN
    • Villarreal-Molina T, Posadas-Romero C, Romero-Hidalgo S, et al. The ABCA1 Gene R230C variant is associated with decreased risk of premature coronary artery disease: The Genetics of Atherosclerotic Disease (GEA) Study. PLoS One. 2012;7(11):e49285.
    • (2012) PLoS One , vol.7 , Issue.11 , pp. 49285
    • Villarreal-Molina, T.1    Posadas-Romero, C.2    Romero-Hidalgo, S.3
  • 50
    • 75149124430 scopus 로고    scopus 로고
    • Role of HDL, ABCA1, and ABCG1 transporters in cholesterol efflux and immune responses
    • 19797709 10.1161/ATVBAHA.108.179283 1:CAS:528:DC%2BC3cXlslaiuw%3D%3D
    • Yvan-Charvet L, Wang N, Tall AR. Role of HDL, ABCA1, and ABCG1 transporters in cholesterol efflux and immune responses. Arterioscler Thromb Vasc Biol. 2010;30(2):139-43.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , Issue.2 , pp. 139-143
    • Yvan-Charvet, L.1    Wang, N.2    Tall, A.R.3
  • 51
    • 84861093038 scopus 로고    scopus 로고
    • MicroRNAs: Emerging roles in lipid and lipoprotein metabolism
    • 22488426 10.1097/MOL.0b013e3283534c9f 1:CAS:528:DC%2BC38XmvVKmt7Y%3D
    • Sacco J, Adeli K. MicroRNAs: emerging roles in lipid and lipoprotein metabolism. Curr Opin Lipidol. 2012;23(3):220-5.
    • (2012) Curr Opin Lipidol , vol.23 , Issue.3 , pp. 220-225
    • Sacco, J.1    Adeli, K.2
  • 52
    • 77955129487 scopus 로고    scopus 로고
    • Liver x receptor signaling pathways and atherosclerosis
    • 20631351 10.1161/ATVBAHA.109.191197 1:CAS:528:DC%2BC3cXovFegtbs%3D
    • Calkin AC, Tontonoz P. Liver x receptor signaling pathways and atherosclerosis. Arterioscler Thromb Vasc Biol. 2010;30(8):1513-8.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , Issue.8 , pp. 1513-1518
    • Calkin, A.C.1    Tontonoz, P.2
  • 53
    • 84861233212 scopus 로고    scopus 로고
    • Liver X receptors, atherosclerosis and inflammation
    • 22419222 10.1007/s11883-012-0239-y 1:CAS:528:DC%2BC38XmvFeks7g%3D
    • Michael DR, Ashlin TG, Buckley ML, Ramji DP. Liver X receptors, atherosclerosis and inflammation. Curr Atheroscler Rep. 2012;14(3):284-93.
    • (2012) Curr Atheroscler Rep , vol.14 , Issue.3 , pp. 284-293
    • Michael, D.R.1    Ashlin, T.G.2    Buckley, M.L.3    Ramji, D.P.4
  • 54
    • 84860548049 scopus 로고    scopus 로고
    • Liver LXRα expression is crucial for whole body cholesterol homeostasis and reverse cholesterol transport in mice
    • 22484817 10.1172/JCI59817 1:CAS:528:DC%2BC38Xmsl2jsro%3D
    • Zhang Y, Breevoort SR, Angdisen J, et al. Liver LXRα expression is crucial for whole body cholesterol homeostasis and reverse cholesterol transport in mice. J Clin Invest. 2012;122(5):1688-99.
    • (2012) J Clin Invest , vol.122 , Issue.5 , pp. 1688-1699
    • Zhang, Y.1    Breevoort, S.R.2    Angdisen, J.3
  • 55
    • 80054971110 scopus 로고    scopus 로고
    • Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides
    • 22012398 10.1038/nature10486 1:CAS:528:DC%2BC3MXhtlChtL%2FK
    • Rayner KJ, Esau CC, Hussain FN, et al. Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides. Nature. 2011;478(7369):404-7.
    • (2011) Nature , vol.478 , Issue.7369 , pp. 404-407
    • Rayner, K.J.1    Esau, C.C.2    Hussain, F.N.3
  • 57
    • 79955880471 scopus 로고    scopus 로고
    • Lecithin cholesterol acyltransferase: An anti- or pro-atherogenic factor?
    • 21331766 10.1007/s11883-011-0171-6 1:CAS:528:DC%2BC3MXlsFKht7g%3D
    • Rousset X, Shamburek R, Vaisman B, et al. Lecithin cholesterol acyltransferase: an anti- or pro-atherogenic factor? Curr Atheroscler Rep. 2011;13(3):249-56.
    • (2011) Curr Atheroscler Rep , vol.13 , Issue.3 , pp. 249-256
    • Rousset, X.1    Shamburek, R.2    Vaisman, B.3
  • 59
    • 70350480977 scopus 로고    scopus 로고
    • In vivo quantification of carotid artery wall dimensions: 3.0-Tesla MRI versus B-mode ultrasound imaging
    • 19808598 10.1161/CIRCIMAGING.108.788059 1:STN:280:DC%2BD1MnnsVSrtA%3D%3D
    • Duivenvoorden R, De Groot E, Elsen BM, et al. In vivo quantification of carotid artery wall dimensions: 3.0-Tesla MRI versus B-mode ultrasound imaging. Circ Cardiovasc Imaging. 2009;2(3):235-42.
    • (2009) Circ Cardiovasc Imaging , vol.2 , Issue.3 , pp. 235-242
    • Duivenvoorden, R.1    De Groot, E.2    Elsen, B.M.3
  • 60
    • 82455194933 scopus 로고    scopus 로고
    • Carriers of lecithin cholesterol acyltransferase gene mutations have accelerated atherogenesis as assessed by carotid 3.0-T magnetic resonance imaging [corrected]
    • 22133847 10.1016/j.jacc.2010.11.092 1:CAS:528:DC%2BC38XhtlOnsro%3D
    • Duivenvoorden R, Holleboom AG, Van den Bogaard B, et al. Carriers of lecithin cholesterol acyltransferase gene mutations have accelerated atherogenesis as assessed by carotid 3.0-T magnetic resonance imaging [corrected]. J Am Coll Cardiol. 2011;58(24):2481-7.
    • (2011) J Am Coll Cardiol , vol.58 , Issue.24 , pp. 2481-2487
    • Duivenvoorden, R.1    Holleboom, A.G.2    Van Den Bogaard, B.3
  • 61
    • 84869497153 scopus 로고    scopus 로고
    • Patients with low HDL-cholesterol caused by mutations in LCAT have increased arterial stiffness
    • 23078883 10.1016/j.atherosclerosis.2012.09.022
    • Van den Bogaard B, Holleboom AG, Duivenvoorden R, et al. Patients with low HDL-cholesterol caused by mutations in LCAT have increased arterial stiffness. Atherosclerosis. 2012;225(2):481-5.
    • (2012) Atherosclerosis , vol.225 , Issue.2 , pp. 481-485
    • Van Den Bogaard, B.1    Holleboom, A.G.2    Duivenvoorden, R.3
  • 62
    • 84878115658 scopus 로고    scopus 로고
    • AlphacorePharma, Press release October 9 2012
    • AlphacorePharma, Press release October 9 2012. Available from: www.alphacorepharm/in-the-news.
  • 63
    • 84857632360 scopus 로고    scopus 로고
    • Role of plasma phospholipid transfer protein in lipid and lipoprotein metabolism
    • 21736953 10.1016/j.bbalip.2011.06.013 1:CAS:528:DC%2BC38XjtFWnsrc%3D
    • Albers JJ, Vuletic S, Cheung MC. Role of plasma phospholipid transfer protein in lipid and lipoprotein metabolism. Biochim Biophys Acta. 2012;1821(3):345-57.
    • (2012) Biochim Biophys Acta , vol.1821 , Issue.3 , pp. 345-357
    • Albers, J.J.1    Vuletic, S.2    Cheung, M.C.3
  • 64
    • 79955928267 scopus 로고    scopus 로고
    • Role of phospholipid transfer protein in high-density lipoprotein- mediated reverse cholesterol transport
    • 21365262 10.1007/s11883-011-0172-5 1:CAS:528:DC%2BC3MXlsFKht7k%3D
    • Yazdanyar A, Yeang C, Jiang X-C. Role of phospholipid transfer protein in high-density lipoprotein- mediated reverse cholesterol transport. Curr Atheroscler Rep. 2011;13(3):242-8.
    • (2011) Curr Atheroscler Rep , vol.13 , Issue.3 , pp. 242-248
    • Yazdanyar, A.1    Yeang, C.2    Jiang, X.-C.3
  • 65
    • 60549106823 scopus 로고    scopus 로고
    • Human plasma phospholipid transfer protein specific activity is correlated with HDL size: Implications for lipoprotein physiology
    • 19162221 10.1016/j.bbalip.2008.12.010 1:CAS:528:DC%2BD1MXisFWqt7Y%3D
    • Cheung MC, Wolfbauer G, Deguchi H, et al. Human plasma phospholipid transfer protein specific activity is correlated with HDL size: implications for lipoprotein physiology. Biochim Biophys Acta. 2009;1791(3):206-11.
    • (2009) Biochim Biophys Acta , vol.1791 , Issue.3 , pp. 206-211
    • Cheung, M.C.1    Wolfbauer, G.2    Deguchi, H.3
  • 66
    • 77955423268 scopus 로고    scopus 로고
    • Genetic variation at the phospholipid transfer protein locus affects its activity and high-density lipoprotein size and is a novel marker of cardiovascular disease susceptibility
    • 20644014 10.1161/CIRCULATIONAHA.109.912519 1:CAS:528:DC%2BC3cXpslWnt7c%3D
    • Vergeer M, Boekholdt SM, Sandhu MS, et al. Genetic variation at the phospholipid transfer protein locus affects its activity and high-density lipoprotein size and is a novel marker of cardiovascular disease susceptibility. Circulation. 2010;122(5):470-7.
    • (2010) Circulation , vol.122 , Issue.5 , pp. 470-477
    • Vergeer, M.1    Boekholdt, S.M.2    Sandhu, M.S.3
  • 67
    • 77951034342 scopus 로고    scopus 로고
    • Genetic and nongenetic sources of variation in phospholipid transfer protein activity
    • 19965587 10.1194/jlr.M000125 1:CAS:528:DC%2BC3cXltlWktrY%3D
    • Jarvik GP, Rajagopalan R, Rosenthal EA, et al. Genetic and nongenetic sources of variation in phospholipid transfer protein activity. J Lipid Res. 2010;51(5):983-90.
    • (2010) J Lipid Res , vol.51 , Issue.5 , pp. 983-990
    • Jarvik, G.P.1    Rajagopalan, R.2    Rosenthal, E.A.3
  • 68
    • 46249107650 scopus 로고    scopus 로고
    • Acute elevation of plasma PLTP activity strongly increases pre-existing atherosclerosis
    • 18421000 10.1161/ATVBAHA.108.165084 1:CAS:528:DC%2BD1cXmvFehtr8%3D
    • Moerland M, Samyn H, Van Gent T, et al. Acute elevation of plasma PLTP activity strongly increases pre-existing atherosclerosis. Arterioscler Thromb Vasc Biol. 2008;28(7):1277-82.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , Issue.7 , pp. 1277-1282
    • Moerland, M.1    Samyn, H.2    Van Gent, T.3
  • 69
    • 77249177694 scopus 로고    scopus 로고
    • Pharmacologic inhibition of phospholipid transfer protein activity reduces apolipoprotein-B secretion from hepatocytes
    • 19933370 10.1124/jpet.109.161232 1:CAS:528:DC%2BC3cXivFCjsbo%3D
    • Luo Y, Shelly L, Sand T, et al. Pharmacologic inhibition of phospholipid transfer protein activity reduces apolipoprotein-B secretion from hepatocytes. J Pharmacol Exp Ther. 2010;332(3):1100-6.
    • (2010) J Pharmacol Exp Ther , vol.332 , Issue.3 , pp. 1100-1106
    • Luo, Y.1    Shelly, L.2    Sand, T.3
  • 71
    • 84863789387 scopus 로고    scopus 로고
    • Cholesteryl ester transfer protein inhibition as a strategy to reduce cardiovascular risk
    • 22550134 10.1194/jlr.R024075 1:CAS:528:DC%2BC38Xht1Ghs7bO
    • Barter PJ, Rye K-A. Cholesteryl ester transfer protein inhibition as a strategy to reduce cardiovascular risk. J Lipid Res. 2012;53(9):1755-66.
    • (2012) J Lipid Res , vol.53 , Issue.9 , pp. 1755-1766
    • Barter, P.J.1    Rye, K.-A.2
  • 72
    • 0029948968 scopus 로고    scopus 로고
    • Increased coronary heart disease in Japanese-American men with mutation in the cholesteryl ester transfer protein gene despite increased HDL levels
    • Zhong S, Sharp DS, Grove JS, et al. Increased coronary heart disease in Japanese-American men with mutation in the cholesteryl ester transfer protein gene despite increased HDL levels. J Clin Invest. 1996;97(12):2917-23. (Pubitemid 26197108)
    • (1996) Journal of Clinical Investigation , vol.97 , Issue.12 , pp. 2917-2923
    • Zhong, S.1    Sharp, D.S.2    Grove, J.S.3    Bruce, C.4    Yano, K.5    Curb, J.D.6    Tall, A.R.7
  • 74
    • 84868530968 scopus 로고    scopus 로고
    • Genetic inhibition of CETP, ischemic vascular disease and mortality, and possible adverse effects
    • 23083790 10.1016/j.jacc.2012.07.045 1:CAS:528:DC%2BC38Xhs1OlurnM This is an interesting study in the light of recent CETP inhibitor drug development. This study showed a significant association between genetic inhibition of CETP and CVD risk
    • Johannsen TH, Frikke-Schmidt R, Schou J, et al. Genetic inhibition of CETP, ischemic vascular disease and mortality, and possible adverse effects. J Am Coll Cardiol. 2012;60(20):2041-8. This is an interesting study in the light of recent CETP inhibitor drug development. This study showed a significant association between genetic inhibition of CETP and CVD risk.
    • (2012) J Am Coll Cardiol , vol.60 , Issue.20 , pp. 2041-2048
    • Johannsen, T.H.1    Frikke-Schmidt, R.2    Schou, J.3
  • 77
    • 67649367650 scopus 로고    scopus 로고
    • Polymorphism in the CETP gene region, HDL cholesterol, and risk of future myocardial infarction: Genomewide analysis among 18 245 initially healthy women from the Women's Genome Health Study
    • 20031564 10.1161/CIRCGENETICS.108.817304 1:CAS:528:DC%2BD1MXhtVymt77I
    • Ridker PM, Paré G, Parker AN, et al. Polymorphism in the CETP gene region, HDL cholesterol, and risk of future myocardial infarction: Genomewide analysis among 18 245 initially healthy women from the Women's Genome Health Study. Circ Cardiovasc Genet. 2009;2(1):26-33.
    • (2009) Circ Cardiovasc Genet , vol.2 , Issue.1 , pp. 26-33
    • Ridker, P.M.1    Paré, G.2    Parker, A.N.3
  • 78
    • 84868552674 scopus 로고    scopus 로고
    • Will cholesteryl ester transfer protein inhibition succeed primarily by lowering low-density lipoprotein cholesterol? Insights from human genetics and clinical trials
    • 23083775 10.1016/j.jacc.2012.08.967 1:CAS:528:DC%2BC38Xhs1OlurnN
    • Kathiresan S. Will cholesteryl ester transfer protein inhibition succeed primarily by lowering low-density lipoprotein cholesterol? Insights from human genetics and clinical trials. J Am Coll Cardiol. 2012;60(20):2049-52.
    • (2012) J Am Coll Cardiol , vol.60 , Issue.20 , pp. 2049-2052
    • Kathiresan, S.1
  • 79
    • 78651352098 scopus 로고    scopus 로고
    • Genetic variant of the scavenger receptor BI in humans
    • 21226579 10.1056/NEJMoa0907687 1:CAS:528:DC%2BC3MXmvFarsQ%3D%3D This was the first study to report SR-B1 variants in humans associated with HDL-C and reduced macrophage cholesterol efflux
    • Vergeer M, Korporaal SJA, Franssen R, et al. Genetic variant of the scavenger receptor BI in humans. N Engl J Med. 2011;364(2):136-45. This was the first study to report SR-B1 variants in humans associated with HDL-C and reduced macrophage cholesterol efflux.
    • (2011) N Engl J Med , vol.364 , Issue.2 , pp. 136-145
    • Vergeer, M.1    Korporaal, S.J.A.2    Franssen, R.3
  • 80
    • 79955597630 scopus 로고    scopus 로고
    • Novel mutations in scavenger receptor BI associated with high HDL cholesterol in humans
    • 21480869 10.1111/j.1399-0004.2011.01682.x 1:CAS:528:DC%2BC3MXnvFKrtLY%3D
    • Brunham LR, Tietjen I, Bochem AE, et al. Novel mutations in scavenger receptor BI associated with high HDL cholesterol in humans. Clin Genet. 2011;79(6):575-81.
    • (2011) Clin Genet , vol.79 , Issue.6 , pp. 575-581
    • Brunham, L.R.1    Tietjen, I.2    Bochem, A.E.3
  • 81
    • 84866661659 scopus 로고    scopus 로고
    • Functional characterization of newly-discovered mutations in human SR-BI
    • 23029167 10.1371/journal.pone.0045660 1:CAS:528:DC%2BC38XhsVelsb7E
    • Chadwick AC, Sahoo D. Functional characterization of newly-discovered mutations in human SR-BI. PLoS One. 2012;7(9):e45660.
    • (2012) PLoS One , vol.7 , Issue.9 , pp. 45660
    • Chadwick, A.C.1    Sahoo, D.2
  • 82
    • 84878041582 scopus 로고    scopus 로고
    • The impact of partial and complete loss of function mutations in endothelial lipase on HDL levels and functionality in humans
    • doi: 10.1161/CIRCGENETICS.111.962613
    • Singaraja RR, Sivapalaratnam S, Hovingh K, et al. The impact of partial and complete loss of function mutations in endothelial lipase on HDL levels and functionality in humans. Circ Cardiovasc Genet. 2012. doi: 10.1161/CIRCGENETICS. 111.962613.
    • (2012) Circ Cardiovasc Genet
    • Singaraja, R.R.1    Sivapalaratnam, S.2    Hovingh, K.3
  • 83
    • 77955281827 scopus 로고    scopus 로고
    • Lack of association between common genetic variation in endothelial lipase (LIPG) and the risk for CAD and DVT
    • 20466371 10.1016/j.atherosclerosis.2010.04.004 1:CAS:528: DC%2BC3cXps1Cls7g%3D
    • Vergeer M, Cohn DM, Boekholdt SM, et al. Lack of association between common genetic variation in endothelial lipase (LIPG) and the risk for CAD and DVT. Atherosclerosis. 2010;211(2):558-64.
    • (2010) Atherosclerosis , vol.211 , Issue.2 , pp. 558-564
    • Vergeer, M.1    Cohn, D.M.2    Boekholdt, S.M.3
  • 84
    • 65249186429 scopus 로고    scopus 로고
    • Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans
    • 19287092 1:CAS:528:DC%2BD1MXktlSntLg%3D
    • Edmondson AC, Brown RJ, Kathiresan S, et al. Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans. J Clin Invest. 2009;119(4):1042-50.
    • (2009) J Clin Invest , vol.119 , Issue.4 , pp. 1042-1050
    • Edmondson, A.C.1    Brown, R.J.2    Kathiresan, S.3
  • 85
    • 67650092295 scopus 로고    scopus 로고
    • The T111I variant in the endothelial lipase gene and risk of coronary heart disease in three independent populations
    • 19411665 10.1093/eurheartj/ehp145 1:CAS:528:DC%2BD1MXosVant7o%3D
    • Jensen MK, Rimm EB, Mukamal KJ, et al. The T111I variant in the endothelial lipase gene and risk of coronary heart disease in three independent populations. Eur Heart J. 2009;30(13):1584-9.
    • (2009) Eur Heart J , vol.30 , Issue.13 , pp. 1584-1589
    • Jensen, M.K.1    Rimm, E.B.2    Mukamal, K.J.3
  • 87
    • 78149245489 scopus 로고    scopus 로고
    • Genetic variants influencing circulating lipid levels and risk of coronary artery disease
    • 20864672 10.1161/ATVBAHA.109.201020 1:CAS:528:DC%2BC3cXhtlSqtb3O
    • Waterworth DM, Ricketts SL, Song K, et al. Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arterioscler Thromb Vasc Biol. 2010;30(11):2264-76.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , Issue.11 , pp. 2264-2276
    • Waterworth, D.M.1    Ricketts, S.L.2    Song, K.3
  • 88
    • 84866866856 scopus 로고    scopus 로고
    • Association of genetic variants influencing lipid levels with coronary artery disease in Japanese individuals
    • 23050023 10.1371/journal.pone.0046385 1:CAS:528:DC%2BC38XhsVOlsr3I
    • Takeuchi F, Isono M, Katsuya T, et al. Association of genetic variants influencing lipid levels with coronary artery disease in Japanese individuals. PLoS One. 2012;7(9):e46385.
    • (2012) PLoS One , vol.7 , Issue.9 , pp. 46385
    • Takeuchi, F.1    Isono, M.2    Katsuya, T.3
  • 89
    • 84865247399 scopus 로고    scopus 로고
    • Genome-wide association study validation identifies novel loci for atherosclerotic cardiovascular disease
    • 22702842 10.1111/j.1538-7836.2012.04815.x 1:CAS:528:DC%2BC38XhsVeht7zM
    • Chen X, Li S, Yang Y, et al. Genome-wide association study validation identifies novel loci for atherosclerotic cardiovascular disease. J Thromb Haemost. 2012;10(8):1508-14.
    • (2012) J Thromb Haemost , vol.10 , Issue.8 , pp. 1508-1514
    • Chen, X.1    Li, S.2    Yang, Y.3
  • 90
    • 79957607662 scopus 로고    scopus 로고
    • Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes
    • 21572415 10.1038/ng.833 1:CAS:528:DC%2BC3MXmtV2htLo%3D
    • Small KS, Hedman AK, Grundberg E, et al. Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes. Nat Genet. 2011;43(6):561-4.
    • (2011) Nat Genet , vol.43 , Issue.6 , pp. 561-564
    • Small, K.S.1    Hedman, A.K.2    Grundberg, E.3
  • 91
    • 79953204259 scopus 로고    scopus 로고
    • Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
    • 21378990 10.1038/ng.784 1:CAS:528:DC%2BC3MXivVSntLg%3D
    • Schunkert H, König IR, Kathiresan S, et al. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet. 2011;43(4):333-8.
    • (2011) Nat Genet , vol.43 , Issue.4 , pp. 333-338
    • Schunkert, H.1    König, I.R.2    Kathiresan, S.3
  • 92
    • 84871969762 scopus 로고    scopus 로고
    • Large-scale association analysis identifies new risk loci for coronary artery disease
    • 23202125 10.1038/ng.2480 This is the largest and most recent meta-analysis on the genetic background of coronary artery disease risk
    • •• Deloukas P, Kanoni S, Willenborg C, et al. Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet. 2012;45:25-33. This is the largest and most recent meta-analysis on the genetic background of coronary artery disease risk.
    • (2012) Nat Genet , vol.45 , pp. 25-33
    • Deloukas, P.1    Kanoni, S.2    Willenborg, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.